Robert Beale (15411601) was a diplomat and administrator who worked at the heart of Elizabethan governance and international policymaking. In spite or perhaps because of the voluminous record he left behind, he has never been the subject of a dedicated biography, and his remarkable life and influence have therefore remained hidden. By thoroughly investigating Beales personal reference archive, which remains largely intact at the British Library, and additional material from archives across the UK, mainland Europe, and the USA, this book brings Beales life into sharp focus: from his shadowy upbringing in Coventry and London, through his first trips to the European mainland in the 1550s, and to his prominent roles in Queen Elizabeths government. By reconstructing the complex web of transnational connections he forged throughout Europe, David Scott Gehring demonstrates for the first time the extent to which these networks and his experiences abroad made him an invaluable agent of the Elizabethan regime. In the process, Gehring reveals Beales broader significance for our understanding of the workings of Elizabethan government, especially the role of second- and third-level players within it, and he recognizes the impossibility of truly understanding Elizabethan England without considering its interactions with and connections to the rest of Europe. The book makes a range of novel contributions, including to understandings of Elizabethan foreign policy, the succession, religion, political life, and intelligence gathering.
Shedding critical new light on the diverse forms of Puritan belief and practice in England, Scotland, and New England, Hall provides a multifaceted account of a cultural movement that judged the Protestant reforms of Elizabeth's reign to be unfinished"--Provided by publisher.
Challenging accepted notions of Elizabethan foreign policy, Gehring argues that the Queen’s relationship with the Protestant Princes of the Holy Roman Empire was more of a success than has been previously thought. Based on extensive archival research, he contends that the enthusiastic and continual correspondence and diplomatic engagement between Elizabeth and these Protestant allies demonstrate a deeply held sympathy between the English Church and State and those of Germany and Denmark.
Robert Beale (15411601) was a diplomat and administrator who worked at the heart of Elizabethan governance and international policymaking. In spite or perhaps because of the voluminous record he left behind, he has never been the subject of a dedicated biography, and his remarkable life and influence have therefore remained hidden. By thoroughly investigating Beales personal reference archive, which remains largely intact at the British Library, and additional material from archives across the UK, mainland Europe, and the USA, this book brings Beales life into sharp focus: from his shadowy upbringing in Coventry and London, through his first trips to the European mainland in the 1550s, and to his prominent roles in Queen Elizabeths government. By reconstructing the complex web of transnational connections he forged throughout Europe, David Scott Gehring demonstrates for the first time the extent to which these networks and his experiences abroad made him an invaluable agent of the Elizabethan regime. In the process, Gehring reveals Beales broader significance for our understanding of the workings of Elizabethan government, especially the role of second- and third-level players within it, and he recognizes the impossibility of truly understanding Elizabethan England without considering its interactions with and connections to the rest of Europe. The book makes a range of novel contributions, including to understandings of Elizabethan foreign policy, the succession, religion, political life, and intelligence gathering.
Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. - Major families of eukaryotic transcription factors described - Mechanisms of gene activation and repression analysed - Structure-function relationships indicated - Interaction between transcription factors and chromatin structure described - Roles in inducible and cell type-specific gene expression - Roles in development, differentiation and human diseases including cancer - Methods of study in vitro and in vivo
As a result of the molecular genetic analysis of development similar mechanisms for the regulation of gene expression are found in a wide range of organisms. In "Development - the Molecular Genetic Approach" these common mechanisms as well as the specific events leading to a differentiated cell are described. Particular items treated are, for example, how asymmetry is achieved, how cell size is determined, how cell division is controlled, how cell lineage influences development, how cells know their position, and how cells communicate during development.
Risks are increasingly regulated by international standards, and scientists play a key role in standardisation. This fascinating book exposes the action of 'invisible colleges' of scientists - loose groups of prominent scientific experts who combine practical experience of risk and control with advisory responsibility - in the formulation of international standards. Drawing upon the domains of medicines, 'novel foods' and food hygiene, David Demortain investigates new regulatory concepts emerging from invisible colleges, highlighting how they shape consensus and pave the way for international.
DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription. - Genetic assays of chromatin modification and remodeling - Histone modifying enzymes - ATP-dependent chromatin remodeling enzymes
If the made-for-television movie has long been regarded as a poor stepchild of the film industry, then telefilm horror has been the most uncelebrated offspring of all. Considered unworthy of critical attention, scary movies made for television have received little notice over the years. Yet millions of fans grew up watching them--especially during the 1970s--and remember them fondly. This exhaustive survey addresses the lack of critical attention by evaluating such films on their own merits. Covering nearly 150 made-for-TV fright movies from the 1970s, the book includes credits, a plot synopsis, and critical commentary for each. From the well-remembered Don't Be Afraid of the Dark to the better-forgotten Look What's Happened to Rosemary's Baby, it's a trustworthy and entertaining guide to the golden age of the televised horror movie.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a 16-chapter reference source on chemical structures and reactions of living cells. The first three chapters of this book contain introductory material on cell structure, molecular architecture, and energetic. The subsequent chapters examine the allosteric effect of the binding structures of oligomeric enzymes, microtubules, viruses, and muscle. These chapters also describe the structures and chemical properties of membranes and of the surrounding cell coats. The discussions then shift to the general properties of enzymes, the kinetics of chemical reactions, and the various mechanisms employed in enzymatic catalysis. Considerable chapters are devoted to the reaction sequences found in metabolism. These chapters particularly examine the carbohydrate and lipid metabolism; photosynthesis; and biosynthesis and catabolism of an enormous number of nitrogenous compounds. The final chapters highlight the genetic and hormonal control of metabolism, development, and brain function. Biochemistry teachers and students will find this book of great value.
For most Americans, the savings and loan industry is defined by the fraud, ineptitude and failures of the 1980s. However, these events overshadow a long history in which thrifts played a key role in helping thousands of households buy homes. First appearing in the 1830s savings and loans, then known as building and loans, encourage their working-class members to adhere to the principles of thrift and mutual co-operation as a way to achieve the 'American Dream' of home ownership. This book traces the development of this industry from its origins as a movement of a loosely affiliated collection of institutions into a major element of America's financial markets. It also analyses how diverse groups of Americans, including women, ethnic Americans and African Americans, used thrifts to improve their lives and elevate their positions in society. Finally the overall historical perspective sheds new light on the events of the 1980s and analyses the efforts to rehabilitate the industry in the 1990s.
The aim of the book is to lay out the foundations and provide a detailed treatment of the subject. It will focus on two main elements in dual phase evolution: the relationship between dual phase evolution and other phase transition phenomena and the advantages of dual phase evolution in evolutionary computation and complex adaptive systems. The book will provide a coherent picture of dual phase evolution that encompasses these two elements and frameworks, methods and techniques to use this concept for problem solving.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Examines the life and accomplishments of this powerful actor through a review of the roles he has played and awards he has received while delving into his personal life and the dramas he managed off-stage, including a sexual harrassment suit and an affair with Ava Gardner.
Fully revised, updated, and extended, the fifth edition of Hollywood’s America provides an important compilation of interpretive essays and primary documents that allows students to read films as cultural artifacts within the contexts of actual past events. A new edition of this classic textbook, which ties movies into the broader narrative of US and film history This fifth edition contains nine new chapters, with a greater overall emphasis on recent film history, and new primary source documents which are unavailable online Entries range from the first experiments with motion pictures all the way to the present day Well-organized within a chronological framework with thematic treatments to provide a valuable resource for students of the history of American film
This book presents a technical review of ecological and life history information on a range of Bornean wildlife species, aimed at identifying what makes these species sensitive to timber harvesting practices and associated impacts. It addresses three audiences: 1) those involved in assessing and regulating timber harvesting activities in Southeast Asia, 2) those involved in trying to achieve conservation goals in the region, and 3) those undertaking research to improve multipurpose forest management. This book shows that forest management can be improved in many simple ways to allow timber extraction and wildlife conservation to be more compatible than under current practices. The recommendations can also be valuable to the many governmental and non-governmental organisations promoting sustainable forest management and eco-labelling. Finally, it identifies a number of shortcomings and gaps in knowledge, which the hope can interest the scientific community and promote further research. This review is, an important scientific step toward understanding and improving sustainable forestry practices for long-term biodiversity conservation. Even in the short term, however, significant improvements can be made to improve both conservation and the efficiency of forest management, and there is no need to delay action due to a perceived lack of information. In the longer term it is expected that the recommendations from this review will be implemented, and that further research will continue to help foster an acceptable balance among the choices needed to maintain healthy wildlife populations and biodiversity in a productive forest estate.
Forensic Pathology is a comprehensive reference that uses a case-oriented format to address, explain and guide the reader through the varied topics encountered by forensic pathologists. Developed in response to a severe void in the literature, the book addresses topics ranging from medicolegal investigation of death to death scene investigation, forensic autopsy, and artifacts of resuscitation as well as complications of medical therapy, forensic osteology, forensic odontology, forensic photography, and death certification. The book includes various types of cases, including sudden natural death, asphyxia, motor vehicle collisions, death in custody, child abuse and elder abuse, acute psychiatric and emotional deaths, and pregnancy. It contains sample descriptions of pathological lesions which serve to aid pathologists in reporting their findings to law enforcement agencies, attorneys, and others involved in investigations of sudden death. The concepts outlined in the text are beautifully illustrated by large, colorful photographs. There are also "Do and Don't" sections at the end of each chapter that provide guidance for handling the types of cases examined. This work will benefit not only experienced forensic pathologists, but also hospital pathologists who occasionally performs medicolegal autopsies; doctors in training; medical examiners; law enforcement personnel; crime scene investigators; attorneys; and fellows and students of the medical sciences. - Large, colorful photographs which beautifully illustrate the concepts outlined in the text. - Sample descriptions of pathological lesions which serve to aid pathologists in reporting their findings to law enforcement agencies, attorneys, and others involved in investigations of sudden death. - 'Do and Don't' sections at the end of each chapter which provide guidance for handling the types of cases examined within preceding sections.
Film is an art form with a language and an aesthetic all its own. Since 1979, David Bordwell and Kristin Thompson's Film Art has been the best-selling and most widely respected introduction to the analysis of cinema. Taking a skills-centered approach supported by examples from many periods and countries, the authors help students develop a core set of analytical skills that will enrich their understanding of any film, in any genre. In-depth examples deepen students’ appreciation for how creative choices by filmmakers affect what viewers experience and how they respond. Film Art is generously illustrated with more than 1,000 frame enlargements taken directly from completed films, providing concrete illustrations of key concepts.
The Texture of Contact is a landmark study of Iroquois and European communities and coexistence in eastern North America before the American Revolution. David L. Preston details the ways in which European and Iroquois settlers on the frontiers creatively adapted to each other’s presence, weaving webs of mutually beneficial social, economic, and religious relationships that sustained the peace for most of the eighteenth century. Drawing on a wealth of previously unexamined archival research, Preston describes everyday encounters between Europeans and Indians along the frontiers of the Iroquois Confederacy in the St. Lawrence, Mohawk, Susquehanna, and Ohio valleys. Homesteads, taverns, gristmills, churches, and markets were frequent sites of intercultural exchange and negotiation. Complex diplomatic and trading relationships developed as a result of European and Iroquois settlers bartering material goods. Innovative land-sharing arrangements included the common practice of Euroamerican farmers living as tenants of the Mohawks, sometimes for decades. This study reveals that the everyday lives of Indians and Europeans were far more complex and harmonious than past histories have suggested. Preston’s nuanced comparisons between various settlements also reveal the reasons why peace endured in the Mohawk and St. Lawrence valleys while warfare erupted in the Susquehanna and Ohio valleys. One of the most comprehensive studies of eighteenth-century Iroquois history, The Texture of Contact broadens our understanding of eastern North America’s frontiers and the key role that the Iroquois played in shaping that world.
Stay on the cutting edge of today’s most promising trends in complementary and alternative medical treatments with Dr. David Rakel’s Integrative Medicine, 4th Edition. Written by physicians who are experts in both traditional and integrative medicine, this highly regarded, evidence-based reference covers therapies such as botanicals, supplements, mind-body, lifestyle choices, nutrition, exercise, spirituality, and more. Integrative Medicine, 4th Edition uses a clinical, disease-oriented approach, offering practical guidance for reducing costs and improving patient care. Helps you safely and effectively incorporate complementary and alternative therapies into your everyday practice, while focusing on prevention and wellness for a better quality of life. Uses the reliable SORT method (Strength of Recommendation Taxonomy) to provide evidence-based ratings, grading both the evidence and the relative potential harm. Explains how to make the best use of integrative medicine and the mechanisms by which these therapeutic modalities work, keeping you at the forefront of the trend toward integrative health care. Includes 13 brand-new chapters, covering hot topics such as personalized medicine, MTHFR mutation, food allergy and intolerance, the gut-immune influence on systemic inflammation and disease, chelation therapy, testosterone deficiency, adrenal fatigue, and much more. Features more than 100 significantly revised chapters and hundreds of new figures and tables throughout.
CO-PUBLISHED BY SINAUER ASSOCIATES, INC., AND W. H. FREEMAN AND COMPANY. LIFE HAS EVOLVED. . . from its original publication to this dramatically revitalized Eighth Edition. LIFE has always shown students how biology works, offering an engaging and coherent presentation of the fundamentals of biology by describing the landmark experiments that revealed them. This edition builds on those strengths and introduces several innovations.. As with previous editions, the Eighth Edition will also be available in three paperback volumes: • Volume I The Cell and Heredity, Chapters 1-20 • Volume II Evolution, Diversity and Ecology, Chapters 1, 21-33, 52-57 • Volume III Plants and Animals, Chapters 1, 34-51
From his first appearance in 1912, Tarzan became a multimedia franchise whose cultural influence extended well beyond mere entertainment. The original 20th century superhero, the Lord of the Apes was the inspiration behind such early archetypes as The Shadow and Doc Savage, themselves the basis for heroes like Batman and Superman. Long before Comic-Cons and Trekkies, the first Tarzan fan club was formed in America in 1916, pioneering the fandom movement that pervades modern pop culture. This book examines Tarzan in his various media representations--hunter, warrior, secret agent, fighter of communists and Nazis--and in his numerous story arcs, including crossover adventures featuring historical characters like Arthur Conan Doyle and Nikola Tesla.
**Selected for Doody's Core Titles® 2024 in Veterinary Medicine** Designed for the mixed practice large animal veterinarian, veterinary students, and camelid caretakers alike, Llama and Alpaca Care covers all major body systems, herd health, physical examination, nutrition, reproduction, surgery, anesthesia, and multisystem diseases of llamas and alpacas. Written by world-renowned camelid specialists and experts in the field, this comprehensive and uniquely global text offers quick access to the most current knowledge in this area. With coverage ranging from basic maintenance such as restraint and handling to more complex topics including anesthesia and surgery, this text provides the full range of knowledge required for the management of llamas and alpacas. "..an essential text for anyone working with South American camelids." Reviewed by Claire E. Whitehead on behalf of Veterinary Record, July 2015 - Over 500 full-color images provide detailed, highly illustrated coverage of all major body systems, physical examination, nutrition, anesthesia, fluid therapy, multisystem diseases, and surgical disorders. - World-renowned camelid experts and specialists in the field each bring a specific area of expertise for a uniquely global text. - Comprehensive herd health content includes handling techniques, vaccinations, biosecurity, and protecting the herd from predators. - Coverage of anesthesia and analgesia includes the latest information on pharmacokinetics of anesthetic drugs, chemical restraint, injectable and inhalation anesthesia, neuroanesthesia, and pain management. - Reproduction section contains information on breeding management, lactation, infertility, and embryo transfer. - Nutrition information offers detailed nutritional requirements and discusses feeding management systems and feeding behavior.
This tried and tested introduction to Paul needs little introduction of its own. After considering Paul's importance and influence, and the important sources for the study of Paul, the volume covers the following key topics: the earliest period of Christianity - from Jesus to Paul; Paul's life before and after his 'conversion'; his individual letters; the major elements of his theology; his attitude to Israel and the Jewish law; perspectives on the Pauline assemblies, including their socio-economic location, meeting places, and attitudes towards women; and Paul's legacy in the New Testament and beyond. The volume has been revised throughout and fully updated with respect to bibliography, and to presenting the latest debates surrounding Paul's thought in a manageable format - including those around 'old' and 'new' perspectives, with a new section on the 'radical' new Jewish perspective, and those related to the socio-economic status and character of the Pauline assemblies. The helpful study questions and reading lists have also been revised.
Certain Hollywood movies are now so deeply woven into the cultural fabric that lines of their dialogue - for example, 'Make him an offer he can't refuse' - have been incorporated into everyday discourse. The films explored in this book, which include The Godfather, Jaws, The Big Lebowski, Field of Dreams and The Village, have become important cultural myths, fascinating windows into the schisms, tensions, and problems of American culture. Hollywood Blockbusters: The Anthropology of Popular Movies uses anthropology to understand why these movies have such enduring appeal in this age of fragmented audiences and ever-faster spin cycles. Exploring key anthropological issues from ritual, kinship, gift giving and totemism to literacy, stereotypes, boundaries and warfare, this fascinating book uncovers new insights into the significance of modern film classics for students of Film, Media, Anthropology and American Cultural Studies.
Vermittelt ein umfassendes Verständnis sämtlicher Krankheiten, die bei Ziegen in unterschiedlichen geographischen Lagen und unter einem breiten Spektrum von Haltungsbedingungen auftreten können, von der extensiven Weidehaltung über die intensive Milchproduktion bis zur Heimtierhaltung. Die dritte Auflage von Goat Medicine ist ein umfassendes Referenzwerk für Ziegenkrankheiten in allen Ländern der Welt. Die beiden Autoren ? approbierte Tierärzte mit weltweiter Erfahrung im Bereich Ziegenzucht und -gesundheit ? präsentieren in diesem Werk die neusten Fortschritte bei Diagnose- und Therapieverfahren sowie eine umfassende Betrachtung aller wesentlichen Krankheiten der Ziege. Das Buch enthält maßgebliche, klinisch relevante Informationen zur Erkennung, Diagnose, Behandlung, Bekämpfung und Vorbeugung von Ziegenkrankheiten beim Einzeltier, bei einer Herde oder sogar auf nationaler Ebene. Zum leichteren Verständnis und um die Inhalte des Buchs mühelos erlernbar zu machen, ist das Buch logisch nach Körpersystemen gegliedert und durchgängig mit farbigen Abbildungen illustriert. Behandelt werden u.a. die folgenden Themen: * Bekämpfung wirtschaftlich relevanter Infektionskrankheiten wie der Caprinen Arthritis-Encephalitis, der Paratuberkulose und der Pest der kleinen Wiederkäuer sowie innerer und äußerer Parasiten * Differenzialdiagnose bei chronischem Gewichtsverlust und plötzlichem Tod, Anästhesie und Enthornung/Drüsenentfernung * Ernährung und Stoffwechselkrankheiten, Management der Herdengesundheit und Präventivmedizin * Arzneimittelliste für Ziegen mit empfohlenen Dosierungen sowie Möglichkeiten der Alternativmedizin Wissenschaftler, Forscher, Amtstierärzte, Labordiagnostiker, Industrietierärzte, Veterinärtechniker und behandelnde Tierärzte in aller Welt können sich mit gutem Gewissen auf dieses Buch verlassen und es bei Bedarf jederzeit als umfassendes Referenzwerk zu sämtlichen Themen rund um die Gesundheit und die Krankheiten von Ziegen verwenden.
This text aims to establish biology as a discipline not just a collection of facts. Life develops students' understanding of biological processes with scholarship, a smooth narrative, experimental contexts, art and effective pedagogy.
Lehninger Principles of Biochemistry is the #1 bestseller for the introductory biochemistry course because it brings clarity and coherence to an often unwieldy discipline, offering a thoroughly updated survey of biochemistry’s enduring principles, definitive discoveries, and groundbreaking new advances with each edition. This new Seventh Edition maintains the qualities that have distinguished the text since Albert Lehninger’s original edition—clear writing, careful explanations of difficult concepts, helpful problem-solving support, and insightful communication of contemporary biochemistry’s core ideas, new techniques, and pivotal discoveries. Again, David Nelson and Michael Cox introduce students to an extraordinary amount of exciting new findings without an overwhelming amount of extra discussion or detail. And with this edition, W.H. Freeman and Sapling Learning have teamed up to provide the book’s richest, most completely integrated text/media learning experience yet, through an extraordinary new online resource: SaplingPlus.
An exposition of current understanding of the way that hierarchies of genes control aspects of animal development. Emphasis is placed on the best studied systems, nameley "Drosophila" and the nematode "Caenorhabditis".
In this sweeping, foundational work, Pulitzer Prize–winning historian David Hackett Fischer draws on extensive research to show how enslaved Africans and their descendants enlarged American ideas of freedom in varying ways in different regions of the early United States. African Founders explores the little-known history of how enslaved people from different regions of Africa interacted with colonists of European origins to create new regional cultures in the colonial United States. The Africans brought with them linguistic skills, novel techniques of animal husbandry and farming, and generations-old ethical principles, among other attributes. This startling history reveals how much our country was shaped by these African influences in its early years, producing a new, distinctly American culture. Drawing on decades of research, some of it in western Africa, Fischer recreates the diverse regional life that shaped the early American republic. He shows that there were varieties of slavery in America and varieties of new American culture, from Puritan New England to Dutch New York, Quaker Pennsylvania, cavalier Virginia, coastal Carolina, and Louisiana and Texas. This landmark work of history will transform our understanding of America’s origins.
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