Caribbean Integration Law offers a comprehensive legal analysis of the current treaties and rules governing the two main regional organisations in the Caribbean, the Caribbean Community (CARICOM) and the Organisation of Eastern Caribbean States (OECS). Both organisations are operating under new treaties, the Revised Treaty of Chaguaramas and the Revised Treaty of Basseterre, respectively, which created the CARICOM Single Market and Economy, and the OECS Economic Union. The single market and economic union were built upon principles of free movement of goods, labour, and capital, and a common external tariff. This book reviews the foundations of Caribbean regional integration, the institutional frameworks of the two regional organisations, and fleshes out the scope and context of the legal systems created by the treaties. It also reviews the dispute settlement mechanisms under both treaties, including the increasingly active role of the Caribbean Court of Justice, which allows persons to enforce their treaty rights directly before the Court. The book offers selective comparisons to the current rules governing the European Union, and integrates crucial insights from the field of public international law, including the law of treaties and international institutional law.
Exploring the chromosomal imbalance (aneuploidy) theory of cancer, this volume describes how cancer is initiated and why progression takes years to decades. It clarifies why cancer cells often become drug resistant, provides objective, quantitative measures for detecting cancer and monitoring its progression, and suggests non-toxic strategies of cancer therapy and prevention. The book posits that the autocatalyzed progression of aneuploidy is carcinogenesis. The clarity and unifying simplicity of the theory of chromosomal imbalance has the potential to fundamentally alter the course of cancer research, prevention, diagnosis and treatment.
The old saying ‘safe as houses’ is being challenged around the world like never before. Over recent decades homeowners have experienced the devastating effects of defects like asbestos, leaky buildings, structural failings, and more recently the combustible cladding crisis. The provision of safe and secure housing is a critical starting point to ensure that social value can be delivered in the built environment. However, some of these dangerous defects have resulted in a lack of security, safety, health, well-being, and social value for households and the wider community. The problems homeowners experience go beyond the substantial financial costs for defect rectification. Too often there has been a lack of government and industry support to help the housing consumer through these issues or to prevent them from occurring to begin with. It is time for a rethink and restructure of government policy, support, and industry practices to better protect housing consumers and deliver high-quality and sustainable housing that creates social value. Through evidence-based research and international case studies, this book focuses on the effects that dangerous defects have on the housing consumer. The ongoing construction cladding crisis is used as a primary case study throughout to highlight these implications, with other previous large-scale defect examples, such as leaky buildings and asbestos. Based upon the range of emerging evidence, we propose ideas for policy makers, construction and built environment professionals, owners corporations, and households on how to move forward towards a higher-quality, sustainable, and socially valuable way of residential living. Government policy has long focused on ‘making industry work’ through building regulations and standards. It is now time for greater government and industry focus on the consumer to make ‘consumer protection work’ in the built environment. There is a need to prevent dangerous defects like combustible cladding, better support consumers when defects emerge, and to create buildings for social value rather than minimum standards. Now is the time to build a better future for the end-user.
This extraordinary resource celebrates and expands on Dr. David Spiegel's discovery that a shared intimacy with mortality creates very different concerns in the patient from those that apply in conventional settings. Spiegel and Classen introduce mental health professionals to the awareness as well as the tools they will need to facilitate groups coping with existential crises. The result is a model for helping that actually helps.
A single source of much of the information that doctors and other health care workers need in order to learn if a birth defect or genetic condition can be diagnosed prenatally." -- American Journal of Human Genetics
Here is the most comprehensive and authoritative work on radiologic diagnosis of pediatric gastrointestinal disorders. Packed with hundreds of outstanding clinical images, Pediatric Gastrointestinal Imaging and Intervention offers explicit, step-by-step instructions for performing and interpreting the latest diagnostic techniques. It discusses the imaging methods practitioners are likely to employ, including sonography, plain film and contrast radiography, endoscopy, CT, MRI, nuclear medicine, angiography, and interventional radiology.
Shaping Places explains how towns and cities can turn real estate development to their advantage to create the kind of places where people want to live, work, relax and invest. It contends that the production of quality places which enhance economic prosperity, social cohesion and environmental sustainability require a transformation of market outcomes. The core of the book explores why this is essential, and how it can be delivered, by linking a clear vision for the future with the necessary means to achieve it. Crucially, the book argues that public authorities should seek to shape, regulate and stimulate real estate development so that developers, landowners and funders see real benefit in creating better places. Key to this is seeing planners as market actors, whose potential to shape the built environment depends on their capacity to understand and transform the embedded attitudes and practices of other market actors. This requires planners to be skilled in understanding the political economy of real estate development and successful in changing its outcomes through smart intervention. Drawing on a strong theoretical framework, the book reveals how the future of places will come to be shaped through constant interaction between State and market power. Filled with international examples, essential case studies, color diagrams and photographs, this is essential reading for undergraduate and graduate students taking planning, property, real estate or urban design courses as well as for social science students more widely who wish to know how the shaping of place really occurs.
This book provides essential knowledge and skills to address all the new social work education requirements for placements and practice learning. It will help you successfully pass your compulsory social work placement whilst meeting the Professional Capabilities Framework (PCF) for Social Workers and developing their professional practice. Giving examples of the PCF plus clear exercises, strategies and tips, the book: -Introduces your students to social work in the context of contemporary reforms. -Takes you through each stage of the new placement structure explaining supervision, reflective practice and critical thinking in social work. -Addresses trouble shooting and problem solving on placement. -Helps you prepare for complex casework with individuals, families, groups and communities; address risk in social work; and engage with diverse groups and communities. By using this book, you′ll be armed with the tools you need to get the most out of your placement. David Edmondson is Senior Lecturer in Social Work at Manchester Metropolitan University
The American Civil War began with a laying down of arms by Union troops at Fort Sumter, and it ended with a series of surrenders, most famously at Appomattox Courthouse. But in the intervening four years, both Union and Confederate forces surrendered en masse on scores of other occasions. Indeed, roughly one out of every four soldiers surrendered at some point during the conflict. In no other American war did surrender happen so frequently. David Silkenat here provides the first comprehensive study of Civil War surrender, focusing on the conflicting social, political, and cultural meanings of the action. Looking at the conflict from the perspective of men who surrendered, Silkenat creates new avenues to understand prisoners of war, fighting by Confederate guerillas, the role of southern Unionists, and the experiences of African American soldiers. The experience of surrender also sheds valuable light on the culture of honor, the experience of combat, and the laws of war.
The authoritative guide for Data Monitoring Committees—fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim monitoring of data on safety and efficacy. Data Monitoring Committees (DMCs) are an essential component of many clinical trials, safeguarding trial participants and protecting the credibility and validity of the study. Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition offers practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees, providing a practical overview of the establishment, purpose, and responsibilities of these committees. Examination of topics such as the composition and independence of DMCs, statistical, philosophical and ethical considerations, and determining when a DMC is needed, presents readers with a comprehensive foundational knowledge of clinical trial oversight. Providing recent examples to illustrate DMC principles, this fully-updated guide reflects current developments and practices in clinical trial oversight and offers expanded coverage of emerging issues and challenges in the field. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. • Presents practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees • Illustrates the types of challenging issues Data Monitoring Committees face in practical situations • Provides updated and expanded coverage of topics including regulatory and funding agency guidelines and trial designs and their associated demands and limitations • Includes a new chapter addressing legal issues that affect DMC members and discusses general litigation concerns relevant to clinical research • Expands treatment of current journal publications addressing DMC issues Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition is a must-have text for anyone engaged in DMC activities as well as trial sponsors, clinical trial researchers, regulatory and bioethics professionals, and those associated with clinical trials in academic, government and industry settings.
Management of Cancer in the Older Patient, by Drs. Arash Naeim, David Reuben, and Patricia Ganz, offers the help you need to effectively diagnose, refer, and manage cancer in geriatric patients. You’ll see how to provide effective cancer screening; refer your patients to the right oncologist; deal with comorbidities, frailties, and other complications; navigate end-of-life issues; and much more. A templated, user-friendly format makes it easy to find and apply the answers you need. See how to best manage geriatric cancer patients with help from leading specialists in both geriatrics and oncology Make informed decisions as to when to refer patients to specialists. Provide the supportive care your patients and their families need on issues such as such as mental health, pain, fatigue, nausea, insomnia. Be prepared to help cancer survivors navigate their after-treatment care including adjuvant therapy, side effects, second cancers, quality of life, and other concerns. Offer accurate guidance on ethical issues like competency, end of life, hospice, the role of the caregiver, and more.
Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of established agents has continued to expand, and has permitted rational drug design to play a significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.
Pediatric Ophthalmology and Strabismus is your one-stop source for comprehensive coverage of all the pediatric ophthalmic conditions you are likely to encounter in practice. Extensively updated with expert contributions from leaders in the field and now featuring online instructional videos, this ophthalmology reference delivers all the state-of-the-art guidance you need to effectively diagnose and manage even the most challenging eye diseases and disorders seen in children. Take a holistic approach to patient management that considers the family and ensures optimal doctor-patient relationships.Get a balanced view of etiology, diagnosis, and management, and access unique guidance on the practical problems encountered in real-life clinical cases.Impresses the importance of systemic disease in diagnosis and management. Apply all the latest clinical advances through updated coverage of strabismus diagnosis, management and complications; retinal dystrophies; imaging & investigation; AIDS in children; developmental biology; cerebral visual impairment; child abuse; severe developmental glaucoma; and corneal dystrophies.Get rich visual guidance in diagnosis and management from over 1,700 full-color illustrations.Access advice from the experts with contributions from several new top researchers and clinicians.Find the answers you need quickly and easily through a consistent chapter organization and highly accessible clinical information. Browse the complete contents of Pediatric Ophthalmology and Strabismus online, download all the images, and watch brand-new procedural videos at www.expertconsult.com.
In connection with the recent treatment of radium and the actinides, the Gmelin Institute is carrying out the description of thorium and its compounds. The supplement volumes A 2, A 3 and A 4 with the history, isotopes, uses, the recovery of thorium and general properties of thorium atom and ions, the thermodynamics of its compounds and solutions, and spectroscopic data have already been published. The supplement vol- umes C 1, C 2 and C 3 describing the compounds with the noble gases, hydrogen, oxygen compounds and nitrogen compounds are also available; also has been pu- blished Supplement Volume C 5 describing the compounds with sulfur, selenium, tellurium, and boron. The Supplement Volume D 1 and D 2 describing the properties of thorium ions in solution and the solvent extraction of thorium as well as Supplement Volume E de- scribing the coordination compounds also have been published. The present supplement volume A 5 of the Gmelin Handbook "Thorium" is devoted to the analytical chem- istry of this element, to its biological behavior and to health protection and safety control, including the monitoring of occupational exposure received by personnel. The analytical chemistry of thorium relies mainly on the so-called "classical" determination methods like gravimetric, volumetric, and spectrometric methods. Radiometric methods find also large application in the analytical chemistry of thorium. Presently we have a good understanding of the biological behavior of this danger- ous radioelement, together with a broad knowledge of its metabolism and its effects on humans. The therapeutic decorporation of thorium is also treated in this volume.
Annotation. Offers annotated references to some 800 recent publications on this African country, in sections on economy, ethnic groups, mass media, religion, banking, and science and technology. Includes a chronology, and an introductory essay providing background on Nigeria's history and contemporary issues. This revised bibliography updates the first edition, which was published in 1989. Annotation copyrighted by Book News, Inc., Portland, OR.
This book provides, in a single cohesive source, all the information a health care professional needs to diagnose and select appropriate treatments for the patient with pain associated with cancer. Cancer Pain: Assessment, Diagnosis, and Management is clinically oriented and comprehensively addresses all the issues surrounding modern cancer pain management. The authors provide detailed information on common but difficult to treat cancer pain scenarios. Coverage includes state-of-the-art information on treatment options and discussions of the impact of radiation, chemotherapy, and surgery on pain management. This authoritative, comprehensive clinical reference is essential for all clinicians who treat patients with cancer, including medical oncologists, radiation oncologists, surgeons, pain specialists, anesthesiologists, primary care physicians, internists, and nurses.
Two key regional organisations in the Caribbean, the Caribbean Community and the Organisation of Eastern Caribbean States, had their roles fundamentally expanded in 2001 by treaties that developed a single market and a regional court. This book sets out the new roles of these organisations and their impact on regional integration in the Caribbean.
Microeconomics is a classroom-tested resource for learning the key concepts, essential tools, and applications of microeconomics. This leading textbook enables students to recognize and analyze significant data, patterns, and trends in real markets through its integrated, student-friendly approach to the subject — providing practice problems, hands-on exercises, illustrative examples, and engaging applications that ground theory firmly in the real world. Each chapter, opening with a set of clearly defined learning goals based on the Bloom Taxonomy, features numerous Learning-by-Doing (LBD) problems, mathematical and graphical data, and varied problem sets focused on current events. Now in its sixth edition, the text offers extensive new and revised content throughout. All applications reflect current data and important new developments in the field of economics, including behavioral economics, randomized controlled trials (RCTs) in policy evaluation and design, and computational-based microeconomics. Updated chapter openers, designed to increase student interest, cover topics including the economic impacts of climate change, U.S. household income and spending, surge pricing by Uber and Lyft, the effect of immigration on wages, and advances in robotics, automation, artificial intelligence, and more.
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