A fresh look at the world’s water crises, and the existing and emerging solutions that can be used to solve them It is not your imagination: water crises are more frequent. Our twentieth-century systems for providing the water that grows food, sustains cities, and supports healthy ecosystems are failing to meet the demands of growing population and the challenges brought on by climate change. But the grim news reports—of empty reservoirs, withering crops, failing ecosystems—need not be cause for despair, argues award-winning author David Sedlak. Communities on the front lines of previous water crises have pioneered approaches that are ready to be applied elsewhere. Some have resolved shortages by enhancing water-use efficiency, and others have used moments of crisis to resolve historic disagreements over water rights. Still others have employed treatment technologies that unlock vast quantities of untapped water resources. Sedlak identifies the challenges that society faces, including ineffective policies and outdated infrastructure, and the myriad of tools at our disposal—from emerging technologies in desalination to innovations for recycling wastewater and capturing more of the water that falls on fields and cities. He offers an informed and hopeful approach for rethinking our assumptions about the way that water is managed. With this knowledge we can create a future with clean, abundant, and affordable water for all.
The book covers an extensive range of psychotropic drugs and a number of adjunctive medications. Completely up-to-date, it has been written in accordance with the DSM-IV.
Molecular biology is one of the most rapidly developing and at the same time most exciting disciplines. The key to molecular biology lies in the understanding of nucleic acids - their structure, function, and interaction with proteins. Nucleic Acids and Molecular Biology keeps scientists informed of the explosively growing information and complies with the great interest in this field by offering a continued high standard of review. A substantial part of this volume has been devoted to the analysis of different aspects of nucleic acid-protein-interactions including RNA-protein-interaction.
In the midst of an addiction epidemic, this newly updated edition of The American Society of Addiction Medicine Principles of Addiction Medicine, 5th edition is the sought-after text every addiction researcher and care provider needs. This comprehensive reference text dedicates itself to both the science and treatment of addiction. You’ll receive a thorough grounding in both the scientific principles behind the causes of addiction and the practical aspects of clinical care. Chapters are written by recognized experts, covering areas such as the basic science of addiction medicine; diagnosis, assessment and early intervention; pharmacologic and behavioral interventions; mutual help and twelve-step; and co-occurring addiction, medical and psychiatric disorders—backed by the latest research data and successful treatment methods. Features: Numerous figures, tables and diagrams elucidate the text Chapters include case examples List of data research reports provided at end of each chapter NEW material on Prescription Drug Abuse, Club Drugs, Nursing Roles in Addressing Addiction, Conceptual and Treatment Issues in Behavioral Addictions, Rehabilitation Approaches to Pain Management, Comorbid Pain and Addiction, Pharmacotherapy for Adolescents with Substance Use Disorders, Preventing and Treating Substance Use Disorders in Military Personnel, and more.
Consulting Editor, Dr. Bonita Stanton has worked closely with Guest Editors Drs. David R. Rosenberg and Leslie H. Lundahl to create a current issue devoted to substance abuse in children. Expert authors have written clinical review articles with the goal of providing the pediatrician with the latest information on substances and addiction medicine. The first half of the issue focuses on the following substances: Nicotine Use Disorders in Adolescents; Alcohol Use Disorders in Adolescents; Cannabis Use and Consequences; Medical and Non-Medical Use of Opiates; Stimulant Use and Cognitive Enhancement; and Club Drugs. The second half of the issue focuses on special topics important to pediatricians: Contingency Management for Substance Use Disorders; Behavioral Addictions: Gambling, Gaming, Internet; Juvenile Drug Court: Novel Approach to Treatment; Computer-Assisted Approaches to Substance Abuse Treatment; Co-Morbid Substance Use and Other Psychiatric Disorders; and Drug Use in Pregnant Teens. Readers will come away with the information they need to stay current on this changing field and to improve patient outcomes.
Focusing on cancer in dogs and cats, this extensively updated 4th edition provides comprehensive coverage of the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. Ideal for students, practitioners, and those involved in academic research, this book's full-color images and user-friendly format provide quick and easy access to today's most important information on cancer in the small animal patient. Full-color format throughout and full-color illustrations make information more accessible and provide accurate representations of clinical appearance. Chapters are clustered into four major sections: The Biology and Pathogenesis of Cancer, Diagnostic Procedures for the Cancer Patient, Therapeutic Modalities for the Cancer Patient, and Specific Malignancies in the Small Animal Patient. The consistent format includes incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies in the small animal cancer patient. Features cutting edge information on the complications of cancer, pain management, and the latest treatment modalities. The latest information on the etiology of cancer, including genetic, chemical, physical, and hormonal factors, as well as cancer-causing viruses. Coverage of molecular-targeted therapy of cancer, plus new and emerging therapeutic techniques. New information on molecular diagnostic procedures for the cancer patient. The latest diagnostic imaging techniques in clinical oncology. Discussions of compassion and supportive care, from chronic pain management and nutrition to end-of-life issues and grief support.
Lévi-Strauss is one of the intellectual giants of the twentieth century yet he is a very private and isolated figure, who has been reticent about himself. This book, first published in 1983,provides a fascinating insight into his character through a careful reading of the more speculative passages of his books and interviews. His personal existential and psychological orientation is explored through a structural analysis of Tristes Tropiques, his most personal book, and his writings on art, nature and civilization and through a consideration of his debt to Rousseau. Dr Pace examines in depth Lévi-Strauss’s critique of cultural evolutionism and his attack on the notion of world history. He assesses the political implications of Lévi-Strauss’s own interpretation of human progress through an examination of his debates with Sartre and other Marxists in the 1950s and 1960s and his subsequent movement to the right. The author’s concern throughout is to place the world-view of this great French anthropologist in the context of twentieth-century intellectuals’ struggle to come to grips with cultural relativism and the ‘problem’ of the primitive.
Evolutionary cmputation is one of the fastest growing areas of computer science, partly because of its broad applicability to engineering problems. The methods can be applied to problems as diverse as supply-chain optimization, routing and planning, task assignment, pharmaceutical design, interactive gaming, and many others within the signal processing domain.
Twenty years ago, researchers wishing to identify contaminated areas in aquatic environments generally took water samples, and analysed them badly (as we have since discovered) for a few "pollutants" which were of topical note at the time (and which could be quantified by the methods then available). Today, the use of aquatic organisms as biomonitors in preference to water analysis has become commonplace, and many national and interna tional programmes exist around the world involving such studies. We believe that this trend will continue, and have complete faith in the methodology (when it is employed correctly). We hope that the following text assists in some part in attaining this goal, such that the quality of our most basic global resource -water - is adequately protected in the future. DAVE PHILLIPS, PHIL RAINBOW England, March 1992 vii Acknowledgements Our thanks for contributions to this book are due to several individuals and groups, for varying reasons. Firstly, a co-authored book is always a triumph, and we trust that the following text is an acceptable compromise of the views of two individual authors, on a complex and developing topic. Secondly, many of the ideas herein have crystallised over the last two decades as the field has grown, and we are individually and collectively grateful to a number of researchers for their insight and assistance.
Our knowledge of postoperative thromboembolic complications has increased enormously over the past 2 decades, particularly where diag nosis and prophylaxis are concerned. The 125 I-fibrinogen method of diagnosing thrombosis has completely changed our concept of the frequency, occurrence, and natural course of thrombosis, and it has formed the basis of most thromboprophylactic studies. Concurrently with the development of this diagnostic method, two methods for the prophylaxis of thrombosis have come into vo gue, namely low-dose heparin and dextran. Both these methods were tested in very extensive studies during the seventies, and their value has been unequivocally proved, for reducing both the frequency of thrombosis with and without symptoms, and the frequency of fatal pulmonary embolism. Thromboprophylaxis is not particularly common in surgery; how ever, and its general use is far from uncontested. It has been argued that not only does it complicate surgical activities and make them mo re expensive, but it also involves an unacceptable number of other complications.
With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.
Provide optimal anesthetic care to your young patients with A Practice of Anesthesia in Infants and Children, 5th Edition, by Drs. Charles J. Cote, Jerrold Lerman, and Brian J. Anderson. 110 experts representing 10 different countries on 6 continents bring you complete coverage of the safe, effective administration of general and regional anesthesia to infants and children - covering standard techniques as well as the very latest advances. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Find authoritative answers on everything from preoperative evaluation through neonatal emergencies to the PACU. Get a free laminated pocket reference guide inside the book! Quickly review underlying scientific concepts and benefit from expert information on preoperative assessment and anesthesia management, postoperative care, emergencies, and special procedures. Stay on the cutting edge of management of emergence agitation, sleep-disordered breathing and postoperative vomiting; the use of new devices such as cuffed endotracheal tubes and new airway devices; and much more. Familiarize yourself with the full range of available new drugs, including those used for premedication and emergence from anesthesia. Benefit from numerous new figures and tables that facilitate easier retention of the material; new insights from neonatologists and neonatal pharmacologists; quick summaries of each chapter; and more than 1,000 illustrations that clarify key concepts. Access the entire text online, fully searchable, at www.expertconsult.com, plus an extensive video library covering simulation, pediatric airway management, burn injuries, ultra-sound guided regional anesthesia, and much more; and new online-only sections, tables and figures.
Fjords are both an interface and a buffer between glaciated continents and the oceans. They exhibit a very wide range in environmental conditions, both in dynamics and geography. Some are truly wonders of the world with their dizzying mountain slopes rising sharply from the ocean edge. Others represent some of the harshest conditions on earth, with hurricane winds, extremes in temperature, and catastrophic earth and ice movements. Fjords are unique estuaries and represent a large portion of the earth's coastal zone. Yet they are not very well known, given the increasing population and food pressures, and their present industrial and strategic importance. Temperate zone estuaries have had many more years of intense study, with multiyear data available. Most fjords have not been impacted by man but, if history repeats itself, that condition will not last long. Fjords present some unique environmental problems, such as their usually slow flushing time, a feature common to many silled environments. Thus there is presently a need for management guidelines, which can only be based on a thorough knowledge of the way fjords work. Fjords are, in many respects, perfect natural oceanographic and geologic lab oratories. Source inputs are easily identified and their resulting gradients are well developed. Throughout this book, we emphasize the potential of modeling pro cesses in fjords, with comparisons to other estuary, lake, shelf and slope, and open ocean environments.
Using an integrated, "team" approach, leading authority David N. Herndon, MD, FACS explains how to meet the clinical, physical, psychological, and social needs of every burn patient - and thus achieve optimal recovery and rehabilitation. The 3rd Edition of this definitive reference covers all of the latest advances in the treatment of burns...features new a full-color layout with new color illustrations and clinical photographs. Compiled and edited by one of the world's leading authorities on the management of patients with burns. Discusses the management of burn patients from their initial presentation through long-term rehabilitation. Addresses the clinical, physical, and social needs of the burn patient and emphasizes a multi-faceted, "team approach" to treatment. Covers how to devise integrated treatment programs for different groups of patients, such as elderly and pediatric patients. Uses color illustrations and clinical photographs throughout for the first time-incorporating the illustrative strengths of Barret & Herndon's Color Atlas of Burn Care to provide you with a single source of definitive guidance on diagnosis and management. Presents new chapters on barotrauma and inhalation injury - the tissue bank - the role of exercise - and the use of dermal templates and burn scar resurfacing. Offers fresh perspectives from more than 50% new authors. With more than 100 additional contributing experts
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
This practical and comprehensive casebook illustrates principles of forensic assessment using relevant real-world case material. The author's report and commentary povide "teaching points" that are built around actual case reports from expert forensic psychologists and psychiatrists. Including 43 cases in 23 chapters, the volume examines a broad range of civil, criminal, and family legal questions. Topics include Miranda rights waiver, competence to act as one's own attorney, competence to stand trial, juvenile commitment, sanity at the time of the offense, child custody, termination of parental rights, guardianship, and malpractice.
The Pocket Guide for the Textbook of Pharmacotherapy for Child and Adolescent Psychiatric Disorders is a quick reference guide for psychiatrists, therapists, social workers, and other practitioners to give them the bottom line about each group of medications. This guide, which discusses the use of psychiatric drugs in patients under 18, accompanies this author team's complete book, Textbook of Pharmacotherapy for Child and Adolescent Psychiatric Disorders. Clinical indications, dosage guidelines, side effects, common drug interactions and most tables are retained and updated in this new guide. In addition, the guide includes new research findings that have been published recently. This guide assumes the reader has done a complete assessment of all non-pharmacologic methods before treating the patient with medication. It also assumes that the reader has a working knowledge of the types of medication available for treating psychiatric illnesses. Once everything is taken into account, the practitioner can accurately determine the advantages and disadvantages of a specific treatment and relay that to the patient. Above all, the Pocket Guide for the Textbook of Pharmacotherapy for Child and Adolescent Psychiatric Disorders provides the reader with the practical guidelines to safely and effectively prescribe medication.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Rehabilitation of the geriatric patient poses a unique set of challenges and conditions often not seen in younger patients, but which are common among older adults. This quick, practical resource helps physiatrists and other members of the rehabilitation team overcome these challenges, covering the wide range of topics necessary to provide the highest level of care to this rapidly increasing population. - Presents practical guidance on arthritis and joint replacement, polypharmacy and mobility, swallowing dysfunction, nutritional recommendations, psychiatric and cognitive disorders, assistive technology, and more. - Covers the physiologic changes and epidemiology of aging, osteoporosis and fragility fractures, fall prevention and intervention, and prevention of hospital-acquired deconditioning. - Consolidates today's available information on geriatric rehabilitation into one convenient resource.
The Second Edition of Pharmacotherapy for Child and Adolescent Psychiatric Disorders contains new and expanded chapters on combination therapy pharmacoepidemiology pharmacoeconomics current social, ethical, and legal issues surrounding the administration of psychostimulants and antidepressants to children and teenagers serotonin reuptake inhibitors and discusses techniques to select the most appropriate drug and dosing schedule methods to adjust safely and tailor medical treatments for children during various stages of growth and development the effect of psychoactive drugs on cardiac function Offering nearly 3000 contemporary references to facilitate further research, Pharmacotherapy for Child and Adolescent Psychiatric Disorders, Second Edition is a timely and authoritative guide suitable for psychiatrists, psychologists, pediatricians, pharmaceutical and behavioral scientists, clinical neurologists, primary care physicians, social workers, and graduate and medical school students in these disciplines.
Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.
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