A century and a half before the modern information technology revolution, machinists in the eastern United States created the nation's first high technology industries. In iron foundries and steam-engine works, locomotive works, machine and tool shops, textile-machinery firms, and firearms manufacturers, these resourceful workers pioneered the practice of dispersing technological expertise through communities of practice. In the first book to study this phenomenon since the 1916 classic, English and American Tool Builders, David R. Meyer examines the development of skilled-labor exchange systems, showing how individual metalworking sectors grew and moved outward. He argues that the networked behavior of machinists within and across industries helps explain the rapid transformation of metalworking industries during the antebellum period, building a foundation for the sophisticated, mass production/consumer industries that figured so prominently in the later U.S. economy.
Aune's comprehensive study of early Christian prophecy includes a review of its antecedents (Greco-Roman oracles, ancient Israelite prophecy, prophecy in early Judaism), a discussion of Jesus as prophet, and analyses of Christian prophetic speeches from Paul to the middle of the second century A.D. The most detailed study of early Christian prophecy written, Aune's book places the phenomenon of early Christian prophecy within the larger Greco-Roman world.
This unique textbook focuses exclusively on wound healing of the face and neck, integrating scientific principle with state-of-the-art clinical precept. Detailed, step-by-step surgical techniques demonstrate the best methods of repair of tissue. Contemporary healing concepts encompass the structures of the skin, cartilage, bone, nerve, oral mucosa, middle ear mucosa and airway mucosa. The book benefits from the diverse backgrounds and expertise of each of its authors bringing the reader new insights to the question of why some facial and neck wounds heal satisfactorily and others do not. Dr. Hom suggests a holistic approach to surgery of the face and neck that includes the healing process. Future directions for wound healing of the face and neck are also illuminated. The first section describes the healing aspects of the structures of the face and neck the second section addresses common clinical tissue healing problems encountered and methods to treat them. The third section discusses specific therapies used to optimize healing.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background* Contains twice the number of chapters of the first edition* Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
This book provides an understanding of the role of human activities in accelerating change in global carbon cycling summarizes current knowledge of the contemporary carbon budget. Starting from the geological history, this volume follows a multidisciplinary approach to analyze the role of human activities in perturbing carbon cycling by quantifying changes in different reservoirs and fluxes of carbon with emphasis on the anthropogenic activities, especially after the industrial revolution. It covers the role of different mitigation options – natural ecological, engineered, and geoengineered processes as well as the emerging field of climate engineering in avoiding dangerous abrupt climate change. Although the targeted audience is the educators, students, researchers and scientific community, the simplified analysis and synthesis of current and up to date scientific literature makes the volume easier to understand and a tool policy makers can use to make an informed policy decisions.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
This is the third volume of the immensely useful "Nag Hammadi Bibliography," the first volume of which covered 1948a "1969 and was the first publication in the Nag Hammadi Studies series. The second volume covered 1970a "1994. This third volume provides a complete integration of Supplements II/1a "II/8 to the Bibliography as published in "Novum Testamentum" 1998a "2008, with additions and corrections. This latest update contains 3,063 entries, with the set of three volumes containing 11,580 entries. Nag Hammadi and Gnostic studies continue to be of critical importance for the study of ancient religions in the Graeco-Roman world and for the study of the world of early Christianity, and the present bibliography provides an indispensable reference tool for work in these fields.
In the interstellar medium - which occupies the space between the stars in galaxies - new stars are born from material that is replenished by the debris ejected by stars when they die. This book presents a detailed account of the atomic and molecular processes that give rise to the radiation we observe from the interstellar medium, knowledge that is essential to understanding star formation in our own and other galaxies. This Second Edition has been thoroughly updated and extended to cover related topics in radiation theory. It considers the chemistry of the interstellar medium, both in the present epoch and the early Universe. The book discusses the physics and chemistry of shock waves, which are produced by the jets of matter generated as a consequence of star formation. The methods for calculating rates of collisional excitation of interstellar molecules and atoms are explained, with emphasis on the quantum mechanical method. A comprehensive manual for studying collisional and radiative processes in the interstellar medium, this book will be ideal for researchers involved in calculating the rates of such processes, for those studying the interstellar medium and star formation, as well as for physical chemists specializing in collision theory or in the measurement of the rates of collision processes. Book jacket.
This is a quick-reference guide for psychiatrists, therapists, social workers, and other practitioners about each group of medications. This guide, which discusses the use of psychiatric drugs in patients under 18, accompanies the author team's complete book Textbook of Pharmacotherapy for Child and Adolescent Psychiatric Disorders.; Clinical indications, dosage guidelines, side-effects, common drug interactions and most tables are retained and updated in this guide. the guide provides the reader with the practical guidelines to safely and effectively prescribe medication.
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
Hong Kong has remained the global metropolis for Asia since its founding in the 1840s following the Opium Wars between Britain and China. David Meyer traces its vibrant history from the arrival of the foreign trading firms, when it was established as one of the leading Asian business centres, to its celebrated handover to China in 1997. Throughout this period, Hong Kong has been prominent as a pivotal meeting place of the Chinese and foreign social networks of capital and as such has been China's window on to the world economy, dominating other financial centers such as Singapore and Tokyo. Looking into the future, the author presents an optimistic view of Hong Kong in the twenty-first century, challenging those who predict its decline under Chinese rule. This accessible and broad-ranging look at the story of Hong Kong's success will interest anyone concerned with its past, present and future.
Farms that were on poor soil and distant from markets declined, whereas other farms successfully adjusted production as rural and urban markets expanded and as Midwestern agricultural products flowed eastward after 1840. Rural and urban demand for manufactures in the East supported diverse industrial development and prosperous rural areas and burgeoning cities supplied increasing amounts of capital for investment.
Stream Ecology: Structure and Function of Running Waters is designed to serve as a textbook for advanced undergraduate and graduate students, and as a reference source for specialists in stream ecology and related fields. This Third Edition is thoroughly updated and expanded to incorporate significant advances in our understanding of environmental factors, biological interactions, and ecosystem processes, and how these vary with hydrological, geomorphological, and landscape setting. The broad diversity of running waters – from torrential mountain brooks, to large, lowland rivers, to great river systems whose basins occupy sub-continents – makes river ecosystems appear overwhelming complex. A central theme of this book is that although the settings are often unique, the processes at work in running waters are general and increasingly well understood. Even as our scientific understanding of stream ecosystems rapidly advances, the pressures arising from diverse human activities continue to threaten the health of rivers worldwide. This book presents vital new findings concerning human impacts, and the advances in pollution control, flow management, restoration, and conservation planning that point to practical solutions. Reviews of the first edition: ".. an unusually lucid and judicious reassessment of the state of stream ecology" Science Magazine "..provides an excellent introduction to the area for advanced undergraduates and graduate students..." Limnology & Oceanography "... a valuable reference for all those interested in the ecology of running waters." Transactions of the American Fisheries Society Reviews of the second edition: "Overall, a must for the field centre and a good starter text in stream ecology." (TEN News, October, 2007) "Highly recommended. Upper-division undergraduates through faculty." (P. R. Pinet, CHOICE, Vol. 45 (7), 2008) "... a very good, fluidly readable book which contains the latest key scientific knowledge of the ecology of running waters." (Daniel Graeber, International Review of Hydrobiology, Vol. 94 (2), 2009)
Now in vibrant full color throughout, Rogers’ Textbook of Pediatric Intensive Care, 5th Edition, continues its tradition of excellence as the gold standard in the field. For more than 25 years, readers have turned to this comprehensive resource for clear explanations of both the principles underlying pediatric critical care disease and trauma as well as how these principles are applied in clinical practice. In the 5th Edition, more than 250 global contributors bring you completely up to date on today’s understanding, treatments, technologies, and outcomes regarding critical illness in children.
Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
It is widely recognized nowadays that conical intersections ofmolecular potential-energy surfaces play a key mechanistic role in thespectroscopy of polyatomic molecules, photochemistry and chemicalkinetics. This invaluable book presents a systematic exposition of thecurrent state of knowledge about conical intersections, which has beenelaborated in research papers scattered throughout the chemicalphysics literature.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.
This book develops tools to handle C*-algebras arising as completions of convolution algebras of sections of line bundles over possibly non-Hausdorff groupoids. A fundamental result of Gelfand describes commutative C*-algebras as continuous functions on locally compact Hausdorff spaces. Kumjian, and later Renault, showed that Gelfand's result can be extended to include non-commutative C*-algebras containing a commutative C*-algebra. In their setting, the C*-algebras in question may be described as the completion of convolution algebras of functions on twisted Hausdorff groupoids with respect to a certain norm. However, there are many natural settings in which the Kumjian–Renault theory does not apply, in part because the groupoids which arise are not Hausdorff. In fact, non-Hausdorff groupoids have been a source of surprising counterexamples and technical difficulties for decades. Including numerous illustrative examples, this book extends the Kumjian–Renault theory to a much broader class of C*-algebras. This work will be of interest to researchers and graduate students in the area of groupoid C*-algebras, the interface between dynamical systems and C*-algebras, and related fields.
The United States government invests billions each year on equipping armed forces with the most advanced military equipment. The root of the American defense acquisition system is driven by a combination of national interests and domestic political requirements. While fundamentally the defense acquisition system has produced results for the United States military, improvements are needed in order to continue to move forward in advancing military tactics and technology. Exploring both the systemic and political levels of the system, Sorenson argues that the United States will fall behind if the current defense acquisition system is not reformed. This book brings together elements of this complicated system, such as national security requirements, and the changes that are needed in both the structural and political pillars. A combination of political interests and the needs of the military, serviced by an ever-shrinking defense industry, make a genuine acquisition reform even more difficult, resulting in reform that is more symbolic than genuine.
The Handbook of Mushroom Poisoning provides an in-depth examination of mushroom poisoning, including case examples for each toxic class. The book contains specific chapters on mushroom poison pharmacology and approaches to treatment of cases caused by an unknown mushroom or unknown poison. For those who want a broader background, there are sections on gross and microscopic mushroom identification, general information about the types of toxic substances found in various mushroom families, and tables detailing the results of various field and laboratory tests. For those interested in learning more about mushroom poisonings and how to treat them, this book is a must.
Lawrie's Meat Science has established itself as a standard work for both students and professionals in the meat industry. Its basic theme remains the central importance of biochemistry in understanding the production, storage, processing and eating quality of meat. At a time when so much controversy surrounds meat production and nutrition, Lawrie's meat science, written by Lawrie in collaboration with Ledward, provides a clear guide which takes the reader from the growth and development of meat animals, through the conversion of muscle to meat, to the point of consumption.The seventh edition includes details of significant advances in meat science which have taken place in recent years, especially in areas of eating quality of meat and meat biochemistry. - A standard reference for the meat industry - Discusses the importance of biochemistry in production, storage and processing of meat - Includes significant advances in meat and meat biochemistry
Gold has traditionally been regarded as inactive as a catalytic metal. However, the advent of nanoparticulate gold on high surface area oxide supports has demonstrated its high catalytic activity in many chemical reactions. Gold is active as a heterogeneous catalyst in both gas and liquid phases, and complexes catalyse reactions homogeneously in solution. Many of the reactions being studied will lead to new application areas for catalysis by gold in pollution control, chemical processing, sensors and fuel cell technology. This book describes the properties of gold, the methods for preparing gold catalysts and ways to characterise and use them effectively in reactions. The reaction mechanisms and reasons for the high activities are discussed and the applications for gold catalysis considered./a
A controversial exploration of the origin of religion in the neurology of the human brain. In this book the noted cognitive archaeologist David Lewis-Williams confronts a question that troubles many people in the world today: Is there a supernatural realm that intervenes in the material world of daily life and leads to the evolution of religions? Professor Lewis-Williams first describes how science developed within the cocoon of religion and then shows how the natural functioning of the human brain creates experiences that can lead to belief in a supernatural realm, beings, and interventions. Once people have these experiences, they formulate beliefs about them, and thus creeds are born. Forty thousand years ago, people were leaving traces in the archaeological record of activities that we can label religious, and Lewis-Williams discusses in detail the evidence preserved in the Volp Caves in France. He also shows that mental imagery produced by the functioning of the human brain can be detected in widely separated religious communities such as Hildegard of Bingen’s in medieval Europe or the San hunters of southern Africa.
Proceedings of a SLU-GTE Conference, Held July 27-29, 1987, with Support from St. Lawrence University and General Telephone and Electronics Corporation
Proceedings of a SLU-GTE Conference, Held July 27-29, 1987, with Support from St. Lawrence University and General Telephone and Electronics Corporation
Contains an array of both expository and research articles which represents the proceedings of a conference on commutative harmonic analysis, held in July 1987 and sponsored by St Lawrence University and GTE Corporation. This book is suitable for those beginning research in commutative harmonic analysis.
This book presents papers given at a Conference on Inverse Scattering on the Line, held in June 1990 at the University of Massachusetts, Amherst. A wide variety of topics in inverse problems were covered: inverse scattering problems on the line; inverse problems in higher dimensions; inverse conductivity problems; and numerical methods. In addition, problems from statistical physics were covered, including monodromy problems, quantum inverse scattering, and the Bethe ansatz. One of the aims of the conference was to bring together researchers in a variety of areas of inverse problems which have seen intensive activity in recent years. scattering
The transport system is central to our lives as our means to travel, but also has major impact on our environment. This has become most salient in recent years through its contribution to climate change. However, this perspective has only had a minor impact on the conventional economic analysis and modelling of transport investments, creating a dissonance between the traditional objectives of investment and the strategic need to reduce carbon emissions to Net Zero by 2050. Travel Behaviour Reconsidered in an Era of Decarbonisation argues that our transport networks are mature, and the objective should be to improve operational efficiency. Over the past half century, large public expenditures in roads and railways were justified by an analytic approach to the benefits of investment, primarily the value of the time saved through faster travel, to both business and non-business users of the networks. However, average travel time has not changed over this period. People have taken the benefit of faster travel as better access to people, places, activities and services, with the ensuing enhanced opportunities and choices. This book argues that the basis of orthodox transport economic analysis has been misconceived and a fresh perspective on economic analysis is now needed.
This book examines the coordination of renewable energy policies in the European Union using an innovative theoretical approach to explain national policy making. David Jacobs asks, why are national support instruments for electricity from renewable energy sources converging, even though the harmonisation of these frameworks at the European level has failed? Which causal mechanisms lead to cross-national policy similarities? And what are the implications for policy coordination in the EU? The author traces the evolution of feed-in tariffs - the most successful and most widely used support mechanism for renewable electricity - in Germany, Spain and France. He reveals increasing cross-national policy similarities in feed-in tariff design - despite the failure of harmonizing instruments at the European level. He explains these increasing policy similarities by applying policy convergence theory. Policy convergence can occur voluntarily, based on transnational communication, regulatory competition and technological innovations and these findings have important implications for European policy steering. The key to this book is the interrelation of an innovative theoretical concept (coordination of policies in the international arena via voluntary cooperation) with a very topical empirical research focus - the promotion of renewable energies in the EU. It will be essential reading for scholars and students of environmental policy, comparative politics and European studies.
The book deals with the role of both oxygen- and nitrogen-centred free radicals in inflammatory diseases such as rheumatoid arthritis. The well-known involvement of the superoxide anion radical in the bactericidal action of inflammatory cells suggests that radicals and the inflammatory response are inextricably linked. The widespread involvement of radicals in human disease seems inevitable, because inflammation is such a conspicuous component of human disease. For the first time, the present text integrates contributions from leading research groups who have been investigating the role of radicals within the context of all stages of inflammtion, such as the recruitment of inflammatory cells, their bactericidal action, inflammatory tissue destruction and inflammatory cell death by apoptosis. The chapters are broadly organised so that they trace the clinical course of the acute and chronic inflammtory response, emphasising the therapeutic implications of recent data on the contribution of nitric oxide and related nitrogen-centred species. The book will be of interest to academic and industrial researchers and clinicians with interests in the fields of inflammation or free radical biology.
This updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors — Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong — head the sixth edition of this classic text, which is authored by the world’s foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use.
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.
Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use. Combat stroke with the most comprehensive and updated multimedia resource on the pathophysiology, diagnosis, and management of stroke from leaders in the field
The Handbook of Crime Correlates, Second Edition summarizes more than a century of worldwide research on traits and social conditions associated with criminality and antisocial behavior. Findings are provided in tabular form, enabling readers to determine at a glance the nature of each association. Within each table, results are listed by country, type of crime (or other forms of antisocial behavior), and whether each variable is positively, negatively, or insignificantly associated with offending behavior. Criminal behavior is broken down according to major categories, including violent crime, property crime, drug offenses, sex offenses, delinquency, and recidivism. This book provides a resource for practitioners and academics who are interested in criminal and antisocial behavior. It is relevant to the fields of criminology/criminal justice, sociology, and psychology. No other publication provides as much information about how a wide range of variables—e.g., gender, religion, personality traits, weapons access, alcohol and drug use, social status, geography, and seasonality—correlate with offending behavior. - Includes 600+ tables regarding variables related to criminal behavior - Consolidates 100+ years of academic research on criminal behavior - Findings are identified by country and world regions for easy comparison - Lists criminal-related behaviors according to major categories - Identifies universal crime correlates
Provide optimal anesthetic care to your young patients with A Practice of Anesthesia in Infants and Children, 5th Edition, by Drs. Charles J. Cote, Jerrold Lerman, and Brian J. Anderson. 110 experts representing 10 different countries on 6 continents bring you complete coverage of the safe, effective administration of general and regional anesthesia to infants and children - covering standard techniques as well as the very latest advances. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Find authoritative answers on everything from preoperative evaluation through neonatal emergencies to the PACU. Get a free laminated pocket reference guide inside the book! Quickly review underlying scientific concepts and benefit from expert information on preoperative assessment and anesthesia management, postoperative care, emergencies, and special procedures. Stay on the cutting edge of management of emergence agitation, sleep-disordered breathing and postoperative vomiting; the use of new devices such as cuffed endotracheal tubes and new airway devices; and much more. Familiarize yourself with the full range of available new drugs, including those used for premedication and emergence from anesthesia. Benefit from numerous new figures and tables that facilitate easier retention of the material; new insights from neonatologists and neonatal pharmacologists; quick summaries of each chapter; and more than 1,000 illustrations that clarify key concepts. Access the entire text online, fully searchable, at www.expertconsult.com, plus an extensive video library covering simulation, pediatric airway management, burn injuries, ultra-sound guided regional anesthesia, and much more; and new online-only sections, tables and figures.
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