David R. Bowman's Books

Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

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Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

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Page Count

719

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118210778

ISBN 13

9781118210772

Rehabilitation After Traumatic Brain Injury

By: Blessen C. Eapen,David X. Cifu

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Rehabilitation After Traumatic Brain Injury

By: Blessen C. Eapen,David X. Cifu

Covering the full spectrum of rehabilitation after traumatic brain injury, this practical reference by Drs. Blessen C. Eapen and David X. Cifu presents best practices and considerations for numerous patient populations and their unique needs. In an easy-to-read, concise format, it covers the key information you need to guide your treatment plans and help patients relearn critical life skills and regain their independence. - Covers neuroimaging, neurosurgical and critical care management, management of associated complications after TBI, pharmacotherapy, pain management, sports concussion, assistive technologies, and preparing patients for community reintegration. - Discusses special populations, including pediatric, geriatric, and military and veteran patients. - Consolidates today's available information and guidance in this challenging and diverse area into one convenient resource.

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Page Count

295

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323544576

ISBN 13

9780323544573

By Fire and Ice

Dismantling Chemical Weapons While Preserving the Environment

By: David A. Koplow

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By Fire and Ice

Dismantling Chemical Weapons While Preserving the Environment

By: David A. Koplow

This book, first published in 1997, examines the forced merger between national security interests and environmental policy makers arising from the Chemical Weapons Convention and its requirement to safely dismantle the world’s chemical weapons stockpiles. The two groups had to find a way to intersect and work together, and this book analyses the problems and politics involved.

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Page Count

269

Publisher

Routledge

Published Date

ISBN 10

1000261816

ISBN 13

9781000261813

Textbook of Malignant Haematology

By: Laurent Degos,David C Linch,Bob Löwenberg

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Textbook of Malignant Haematology

By: Laurent Degos,David C Linch,Bob Löwenberg

This textbook provides a concise overview of malignant haematology, including reviews of cell and molecular biology, and implications for new trends in treatment.

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Page Count

972

Publisher

CRC Press

Published Date

ISBN 10

1853173223

ISBN 13

9781853173226

Urban-Rural Interfaces

Linking People and Nature

By: David N. Laband,B. Graeme Lockaby

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Urban-Rural Interfaces

Linking People and Nature

By: David N. Laband,B. Graeme Lockaby

What is the urban–rural interface? Is it a visual phenomenon, a place where country gives way to neighborhoods and shopping areas in a startling way? Is it a simple factor of population density? There is nothing simple about the urban–rural interface—editors David Laband, Graeme Lockaby, and Wayne Zipperer present the broad spectrum of interdisciplinary complexities at play. Organized into three sections on changing ecosystems, changing human dimensions, and the dynamic integration of human and natural systems, this book is a must read for anyone who works in the real world, where natural and human systems are joined. This is the new sustainability science, an emerging discipline that integrates social and economic values with the physical, chemical, and ecological functions of ecosystems. The goal is optimal management, since our human impact is often significant and far-reaching in both space and time.

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Page Count

352

Publisher

John Wiley & Sons

Published Date

ISBN 10

0891186158

ISBN 13

9780891186151

Seemed Like a Good Idea

Alchemy versus Evidence-Based Approaches to Healthcare Management Innovation

By: Mark Pauly,Flaura Winston,Mary Naylor,Kevin Volpp,Lawton Robert Burns,Ralph Muller,David Asch,Rachel Werner,Bimal Desai,Krisda Chaiyachati,Benjamin Chartock

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Seemed Like a Good Idea

Alchemy versus Evidence-Based Approaches to Healthcare Management Innovation

By: Mark Pauly,Flaura Winston,Mary Naylor,Kevin Volpp,Lawton Robert Burns,Ralph Muller,David Asch,Rachel Werner,Bimal Desai,Krisda Chaiyachati,Benjamin Chartock

Consumers, public officials, and even managers of health care and insurance are unhappy about care quality, access, and costs. This book shows that is because efforts to do something about these problems often rely on hope or conjecture, not rigorous evidence of effectiveness. In this book, experts in the field separate the speculative from the proven with regard to how care is rendered, how patients can be in control, how providers should be paid, and how disparities can be reduced – and they also identify the issues for which evidence is currently missing. It provides an antidote to frustration and a clear-eyed guide for forward progress, helping health care and insurance innovators make better decisions on deciding whether to go ahead now based on current evidence, to seek and wait for additional evidence, or to move on to different ideas. It will be useful to practitioners in hospital systems, medical groups, and insurance organizations and can also be used in executive and MBA teaching.

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Page Count

425

Publisher

Cambridge University Press

Published Date

ISBN 10

1009019112

ISBN 13

9781009019118

Introduction to Wildlife and Fisheries

By: David Willis,Charles Scalet,Lester D. Flake

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Introduction to Wildlife and Fisheries

By: David Willis,Charles Scalet,Lester D. Flake

This book integrates the science of wildlife and fisheries. Updates include coverage of geographic information systems and biotelemetry; preferred structures for fish aging; information on diseases such as chronic wasting disease, avian flu, West Nile virus, viral haemorrhagic septicemia, and whirling disease.

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Page Count

480

Publisher

Macmillan

Published Date

ISBN 10

142920446X

ISBN 13

9781429204460

Reintroduction of Fish and Wildlife Populations

By: David S. Jachowski,Joshua J. Millspaugh,Paul L. Angermeier,Rob Slotow

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Reintroduction of Fish and Wildlife Populations

By: David S. Jachowski,Joshua J. Millspaugh,Paul L. Angermeier,Rob Slotow

Reintroduction of Fish and Wildlife Populations provides a practical step-by-step guide to successfully planning, implementing, and evaluating the reestablishment of animal populations in former habitats or their introduction in new environments. In each chapter, experts in reintroduction biology outline a comprehensive synthesis of core concepts, issues, techniques, and perspectives. This manual and reference supports scientists and managers from fisheries and wildlife professions as they plan reintroductions, initiate releases of individuals, and manage restored populations over time. Covering a broad range of taxonomic groups, ecosystems, and global regions, this edited volume is an essential guide for academics, students, and professionals in natural resource management.

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Page Count

408

Publisher

Univ of California Press

Published Date

ISBN 10

0520284615

ISBN 13

9780520284616

Biochemistry

The Chemical Reactions of Living Cells

By: David E. Metzler

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Biochemistry

The Chemical Reactions of Living Cells

By: David E. Metzler

The most comprehensive textbook/reference ever to cover the chemical basis of life, the "Green Bible of Biochemistry" has been a well-respected contribution to the field for more than twenty years. The complex structures that make up cells are described in detail, along with the forces that hold them together, and the chemical reactions that allow for recognition, signaling and movement. There is ample information on the human body, its genome, and the action of muscles, eyes, and the brain. The complete set deals with the natural world, treating the metabolism of bacteria, toxins, antibiotics, specialized compounds made by plants, photosynthesis, luminescence of fireflies, among many other topics.* The most comprehensive biochemistry text reference available on the market* Organized into two volumes, comprising 32 chapters and containing the latest research in the field* Biological content is emphasized: for example, macromolecular structures and enzyme action are discussed

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968

Publisher

Elsevier

Published Date

ISBN 10

0080924700

ISBN 13

9780080924700

Postimperialism and World Politics

By: David G. Becker,Richard L. Sklar

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Postimperialism and World Politics

By: David G. Becker,Richard L. Sklar

Postimperialism is a theory of political and social change inspired by the explosive growth of transnational corporate enterprise during the latter 20th century. Its foundations are derived from two primary sources: political theories of the modern business corporation and class-analytical theories of society. However, the postimperialist theory of class formation is predicated on power relations, a departure from conventional class analysis that renders the theory applicable universally to countries at different stages of economic development. Postimperialist thinkers contend that the formation of a global bourgeoisie, resulting from transnational class coalescence, coincides with the evolution of institutions and public policies that are compatible with socialist as well as capitalist principles. This book provides theoretical contributions to postimperialist theory as well as case studies of both individual countries (Britain, Cuba, the United States) and regions of the world (Africa, postcommunist Europe). It also contains historical analyses of the origins of postimperialist thought in Mexico and the United States. Topics considered include the transfer of cultural and ideological values, multilateral legal responses to transnational oligopolies, the problems of predatory corporate behavior and perceived neoimperial threats, working-class responses to the challenges of transnational enterprise, the effects of resistance to market-based economic reforms, opposition to imperial spheres of influence, and postimperialism's contributions to theories of international politics.

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Page Count

412

Publisher

Praeger

Published Date

ISBN 10

0275966135

ISBN 13

9780275966133

Fundamentals of Water Security

Quantity, Quality, and Equity in a Changing Climate

By: Jim F. Chamberlain,David A. Sabatini

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Fundamentals of Water Security

Quantity, Quality, and Equity in a Changing Climate

By: Jim F. Chamberlain,David A. Sabatini

FUNDAMENTALS OF WATER SECURITY Understand How to Manage Water Resources to Equitably Meet Both Human and Ecological Needs Burgeoning populations and the ever-higher standards of living for those in emerging countries increase the demand on our water resources. What is not increasing, however, is the supply of water and the total amount of water in earth’s biosphere—water that is integral to all standards of living. Fundamentals of Water Security provides a foundation for understanding and managing the quantity-quality-equity nexus of water security in a changing climate. In a broad sense, this volume explores solutions to water security challenges around the world. It is richly illustrated and pedagogically packed with up-to-date information. The text contains chapter learning objectives, foundation sections reviewing quantitative skills, case studies, and vignettes of people who have made important contributions to water security. To further aid comprehension, end-of-chapter problems are included—both qualitative and quantitative, with solutions available to instructors. Finally, extensive references feature books, journal articles, and government and NGO reports. Sample topics discussed include: How the study of water resources has evolved from a focus on physical availability to include social factors and governance How water security affects multiple disciplines across environmental science and engineering, hydrology, geography, water resources, atmospheric science, chemistry, biology, health science, and social and political science fields How to achieve a sufficient quantity and quality of water to equitably meet both immediate and long-term human and ecological needs Analysis of water security in an integrated manner by underscoring the complex interactions between water quantity, water quality, and society Students taking courses on hydrology, water security, and/or water resource management, along with scientists working in fields where water security is a factor will be able to use Fundamentals of Water Security as a comprehensive textbook to understand and achieve water security.

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Page Count

468

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119824664

ISBN 13

9781119824664

Mammals of Africa

By: Jonathan Kingdon,David Happold,Thomas Butynski,Michael Hoffmann,Meredith Happold,Jan Kalina

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Mammals of Africa

By: Jonathan Kingdon,David Happold,Thomas Butynski,Michael Hoffmann,Meredith Happold,Jan Kalina

Mammals of Africa (MoA) is a series of six volumes which describes, in detail, every currently recognized species of African land mammal. This is the first time that such extensive coverage has ever been attempted, and the volumes incorporate the very latest information and detailed discussion of the morphology, distribution, biology and evolution (including reference to fossil and molecular data) of Africa's mammals. With 1,160 species and 16 orders, Africa has the greatest diversity and abundance of mammals in the world. The reasons for this and the mechanisms behind their evolution are given special attention in the series. Each volume follows the same format, with detailed profiles of every species and higher taxa. The series includes some 660 colour illustrations by Jonathan Kingdon and his many drawings highlight details of morphology and behaviour of the species concerned. Diagrams, schematic details and line drawings of skulls and jaws are by Jonathan Kingdon and Meredith Happold. Every species also includes a detailed distribution map. Extensive references alert readers to more detailed information. Volume I: Introductory Chapters and Afrotheria (352 pages) Volume II: Primates (560 pages) Volume III: Rodents, Hares and Rabbits (784 pages) Volume IV: Hedgehogs, Shrews and Bats (800 pages) Volume V: Carnivores, Pangolins, Equids and Rhinoceroses (560 pages) Volume VI: Pigs, Hippopotamuses, Chevrotain, Giraffes, Deer and Bovids (704 pages)

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Page Count

3500

Publisher

A&C Black

Published Date

ISBN 10

1408189968

ISBN 13

9781408189962

The Post-corporate World

Life After Capitalism

By: David C. Korten

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The Post-corporate World

Life After Capitalism

By: David C. Korten

A noted social critic and the author of "When Corporations Rule the World" offers a practical, human-centered alternative to global capitalism run amok.

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348

Publisher

Berrett-Koehler Publishers

Published Date

ISBN 10

1576750515

ISBN 13

9781576750513

The Encyclopedia of American Law

By: David A. Schultz

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The Encyclopedia of American Law

By: David A. Schultz

There's an old saying: Ignorance of the law is no excuse for breaking it. Yet for most people

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561

Publisher

Infobase Publishing

Published Date

ISBN 10

1438109911

ISBN 13

9781438109916

Capital, Labor, and State

The Battle for American Labor Markets from the Civil War to the New Deal

By: David Brian Robertson

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Capital, Labor, and State

The Battle for American Labor Markets from the Civil War to the New Deal

By: David Brian Robertson

Capital, Labor, and State is a systematic and thorough examination of American labor policy from the Civil War to the New Deal. David Brian Robertson skillfully demonstrates that although most industrializing nations began to limit employer freedom and regulate labor conditions in the 1900s, the United States continued to allow total employer discretion in decisions concerning hiring, firing, and workplace conditions. Robertson argues that the American constitution made it much more difficult for the American Federation of Labor, government, and business to cooperate for mutual gain as extensively as their counterparts abroad, so that even at the height of New Deal, American labor market policy remained a patchwork of limited protections, uneven laws, and poor enforcement, lacking basic national standards even for child labor.

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324

Publisher

Rowman & Littlefield

Published Date

ISBN 10

0847697290

ISBN 13

9780847697298

The Neighborhood Project

Using Evolution to Improve My City, One Block at a Time

By: David Sloan Wilson

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The Neighborhood Project

Using Evolution to Improve My City, One Block at a Time

By: David Sloan Wilson

After decades studying creatures great and small, evolutionary biologist David Sloan Wilson had an epiphany: Darwin's theory won't fully prove itself until it improves the quality of human life in a practical sense. And what better place to begin than his hometown of Binghamton, New York? Making a difference in his own city would provide a model for cities everywhere, which have become the habitat for over half of the people on earth. Inspired to become an agent of change, Wilson descended on Binghamton with a scientist's eye and looked at its toughest questions, such as how to empower neighborhoods and how best to teach our children. He combined the latest research methods from experimental economics with studies of holiday decorations and garage sales. Drawing upon examples from nature as diverse as water striders, wasps, and crows, Wilson's scientific odyssey took him around the world, from a cave in southern Africa that preserved the dawn of human culture to the Vatican in Rome. Along the way, he spoke with dozens of fellow scientists, whose stories he relates along with his own. Wilson's remarkable findings help us to understand how we must become wise managers of evolutionary processes to accomplish positive change at all scales, from effective therapies for individuals, to empowering neighborhoods, to regulating the worldwide economy. With an ambitious scope that spans biology, sociology, religion, and economics, The Neighborhood Project is a memoir, a practical handbook for improving the quality of life, and an exploration of the big questions long pondered by religious sages, philosophers, and storytellers. Approaching the same questions from an evolutionary perspective shows, as never before, how places define us.

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Page Count

327

Publisher

Little, Brown

Published Date

ISBN 10

0316175250

ISBN 13

9780316175258

Melodrama Unveiled

American Theater and Culture, 1800-1850

By: David Grimsted

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Melodrama Unveiled

American Theater and Culture, 1800-1850

By: David Grimsted

David Grimsted's Melodrama Unveiled explores early American drama to try to understand why such severely limited plays were so popular for so long. Concerned with both the plays and the dramatic settings that gave them life, Grimsted offers us rich descriptions of the interaction of performers, audiences, critics, managers, and stage mechanics. Because these plays had to appeal immediately and directly to diverse audiences, they provide dramatic clues to the least common denominator of social values and concerns. In considering both the context and content of popular culture, Grimsted's book suggests how theater reflected the rapidly changing society of antebellum America.

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312

Publisher

Univ of California Press

Published Date

ISBN 10

0520059964

ISBN 13

9780520059962

Systems Biology of Tumor Physiology

Rethinking the Past, Defining the Future

By: David H. Nguyen

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Systems Biology of Tumor Physiology

Rethinking the Past, Defining the Future

By: David H. Nguyen

This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor microenvironment view. Reductionistic studies of one gene at a time have given way to systems biology approaches that analyze the whole genome (omics) at the same time. However, this text combines the complex levels studying cancer at the molecular biology level, endocrinology level, and transcriptomics level. What researchers are now realizing is that there is a need to combine omics with physiology concepts in order to better understand cancer and this book will give insight to the merging of these two fields in order to define how cancer is studied in the future.

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Springer

Published Date

ISBN 10

3319256017

ISBN 13

9783319256016

Understanding Media Psychology

By: Gayle S. Stever,David C. Giles,J. David Cohen,Mary E. Myers

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Understanding Media Psychology

By: Gayle S. Stever,David C. Giles,J. David Cohen,Mary E. Myers

Understanding Media Psychology is the perfect introductory textbook to the growing field of media psychology and its importance in society, summarizing key concepts and theories to provide an overview of topics in the field. Media is present in almost every area of life today, and is an area of study that will only increase in importance as the world becomes ever more interconnected. Written by a team of expert authors, this book will help readers to understand the structures, influences, and theories around media psychology. Covering core areas such as positive media psychology, the effects of gaming, violence, advertising, and pornography, the authors critically engage with contemporary discussions around propaganda, fake news, deepfakes, and the ways media have informed the COVID-19 pandemic. Particular care is also given to addressing the interaction between issues of social justice and the media, as well as the effects media has on both the members of marginalized groups and the way those groups are perceived. A final chapter addresses the nature of the field moving forward, and how it will continue to interact with closely related areas of study. Containing a range of pedagogical features throughout to aid teaching and student learning, including vocabulary and key terms, discussion questions, and boxed examples, this is an essential resource for media psychology courses at the undergraduate and introductory master’s level globally.

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Page Count

408

Publisher

Routledge

Published Date

ISBN 10

1000457877

ISBN 13

9781000457872

Book's by David R. Bowman

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