With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery.Setting the stage for subsequent material, the firs
Do Not Go Gentle, first published in 1960, is a poignant novel about the U.S. Marines in World War II. The book focuses on Norman MacLeod, growing up in the tough Depression-era town of Butte, Montana. After his father succumbs to a mining-related disease, young Norman leaves school and also begins working in the copper mines. Following the death of his closest friend in an mine accident and the moving of his mother and sister to relatives back East, Norman enlists in the Marines. The book follows MacLeod through boot camp, life on and off base, and then to the South Pacific where MacLeod and his fellow Marines face both their fears and the Japanese. On leave in the U.S., Norm visits the wife of a killed comrade, and begins a relationship with her. Filled with gritty scenes and no-holds-barred dialog, Do Not Go Gentle remains a minor classic in the field of novels about men at war.
Tracing the legacies of the small farmers displaced and scattered in nineteenth-century Scotland, this is “a powerful, poetic, personal Highland Odyssey” (Times Literary Supplement). In the Clearances of the nineteenth century, crofts—once the mainstay of Highland life in Scotland—were swept away as the land was put over to sheep grazing. Many of the people of the Highlands and islands of Scotland were forced from their homes by landowners in the Clearances. Some fled to Nova Scotia and beyond. In this book, David Craig sets out to discover how many of their stories survive in the memories of their descendants. He travels through twenty-one islands in Scotland and Canada, many thousands of miles of moor and glen, and presents the words of men and women of both countries as they recount the suffering of their forebears. “[David] has the eye, the imagination and the descriptive density of early Bruce Chatwin.” —Toronto Globe & Mail
The ESC Textbook of Thrombosis is the third iteration of Therapeutic Advances in Thrombosis. Now a new addition to the European Society of Cardiology (ESC) publications portfolio, it is informed by the work of the ESC's Working Group on Thrombosis. Written by internationally renowned experts in the field of thrombosis, the textbook presents an up-to-date and in-depth review of all aspects of thrombosis and antithrombotic therapies. Not only does it reflect contemporary European guidelines from the ESC but also it also summarizes the latest evidence from clinical trials. Covering the topic in great detail with thirty-one chapters, the textbook is split into four sections: Pathophysiology of thrombosis, Clinical pharmacology of antithrombotic drugs, Therapeutic strategies, and Special situations. Appealing to the large community of cardiovascular healthcare specialists in Europe and across the world, the textbook is a must read for cardiologists dealing with acute and chronic coronary syndromes, atrial fibrillation, artificial heart valves and pulmonary embolism. It will also appeal to cardiac surgeons, cardiovascular researchers, and general physicians alike.
Meant for quick retrieval of vital information regarding the management of nutritional issues in patients with gastroenterological problems--either primary or as the consequence of other medical disorders, such as diabetes, hyperlipidemia and obesity. The book addresses normal physiology and pathophysiology, and offers chapters on diseases that can lead to specific nutritional problems. The clinical focus is on therapeutic nutrition and dietary management.
This is the first book to take a comprehensive view of the historical geography of Scotland since the Union. The period is divided into sections separated by the Napoleonic Wars and the First World War, and each section offers a general view followed by detailed studies giving a balanced coverage of regional and urban-rural criteria, and the economic infrastructure. The book contains a number of original researches and Dr Turnock attempts to set the Scottish experience in a framework of general ideas on modernisation.
This completely revised and updated Fourth Edition of the Atlas of Diabetes Mellitus provides a broad coverage of all aspects of diabetes mellitus and an extensive collection of common and rare clinical images. It aims to provide an invaluable resource for anyone interested in the management of this ubiquitous clinical condition including primary care/ family physicians, endocrinologists, physicians in training, diabetic specialist nurses and other key professionals who are likely to be involved in the care of patients with diabetes mellitus.
Providing clinicians with the latest developments in research, this new edition of Type 1 Diabetes is a succinct and practical guide to the diagnosis, evaluation, and management of Type 1 diabetes. Part of the Oxford Diabetes Library series, this pocketbook contains 12 fully updated chapters on key topics such as history, epidemiology, aetiology, presentation, insulin treatment, and microvascular and macrovascular complications. It also features new chapters on technology, diet and lifestyle, and pregnancy planning to ensure the reader is fully equipped with the latest understanding of Type 1 diabetes.
This updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors — Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong — head the sixth edition of this classic text, which is authored by the world’s foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use.
Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use. Combat stroke with the most comprehensive and updated multimedia resource on the pathophysiology, diagnosis, and management of stroke from leaders in the field
Smith, Hogan, & Ormerod's Criminal Law is rightly regarded as the leading doctrinal textbook on criminal law in England and Wales. The book owes its consistent popularity to its depth of analysis, breadth of coverage, and accessible style. Over fifty years since the publication of the first edition, Professor David Ormerod and Karl Laird continue the tradition set down by Professors Sir John Smith and Brian Hogan by producing a textbook of unrivalled quality. The text continues to be an invaluable resource for undergraduate students and an essential reference source for criminal law practitioners. Digital formats and resources The sixteenth edition is available for students and institutions to purchase in a variety of formats, and is supported by online resources. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks A selection of online resources accompany this text, including: - A selection of additional online chapters - A full bibliography arranged alphabetically and by chapter - Annual updates
Smith, Hogan, & Ormerod's Criminal Law is rightly regarded as the leading doctrinal textbook on criminal law in England and Wales. Published in its first edition over fifty years ago, it continues to be a key text for undergraduates and an essential reference source for practitioners.
Criminal Law' is written with the needs of the student foremost in mind to provide, more than ever, as modern and as comprehensive an exposition of the criminal law as he or she could possibly require.
Another title in the award winning ‘Practical Manual’ series from Wiley-Blackwell, following on from Edmonds, Foster and Sanders‘ A Practical Manual of Diabetic Foot Care – winner of the British Medical Association’s Medical Book of the Year Award 2004. This practical clinical manual covers the diagnosis, treatment and long-term management of eye problems in people with diabetes, with a strong emphasis on the importance of early diagnosis. Edited and authored by world-renowned experts from leading centres, A Practical Manual of Diabetic Retinopathy Management presents evidence-based guidance relevant for a global audience. High quality photographs uniquely illustrate the lesions that occur in diabetic retinopathy and diagrams show the surgical techniques involved in vitreoretinal surgery for advanced stages of the disease Numerous real life case histories demonstrate the scenarios that one is likely to come across in a clinic treating patients with diabetic retinopathy The best colour guide to the spectrum of changes that occur in diabetic retinopathy This bookis a richly illustrated manual on the management of all stages of diabetic retinopathy, ideal for diabetologists, general endocrinologists who see patients with diabetes, retinal screeners, ophthalmologists and any other healthcare professionals involved in the care and management of diabetes.
As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.
Stay on the cutting edge of today’s most promising trends in complementary and alternative medical treatments with Dr. David Rakel’s Integrative Medicine, 4th Edition. Written by physicians who are experts in both traditional and integrative medicine, this highly regarded, evidence-based reference covers therapies such as botanicals, supplements, mind-body, lifestyle choices, nutrition, exercise, spirituality, and more. Integrative Medicine, 4th Edition uses a clinical, disease-oriented approach, offering practical guidance for reducing costs and improving patient care. Helps you safely and effectively incorporate complementary and alternative therapies into your everyday practice, while focusing on prevention and wellness for a better quality of life. Uses the reliable SORT method (Strength of Recommendation Taxonomy) to provide evidence-based ratings, grading both the evidence and the relative potential harm. Explains how to make the best use of integrative medicine and the mechanisms by which these therapeutic modalities work, keeping you at the forefront of the trend toward integrative health care. Includes 13 brand-new chapters, covering hot topics such as personalized medicine, MTHFR mutation, food allergy and intolerance, the gut-immune influence on systemic inflammation and disease, chelation therapy, testosterone deficiency, adrenal fatigue, and much more. Features more than 100 significantly revised chapters and hundreds of new figures and tables throughout.
Counterstrain -- Acupuncture for headache -- Acupuncture for nausea and vomiting -- Saline nasal irrigation -- Bioenergetics -- Integrating spiritual assessment and care -- Therapeutic homeopathy -- Human energetic therapies -- Other therapeutic considerations -- Creating a greener clinic: the impact of global warming on health -- Creating ceremony and ritual in the medical encounter -- Appendix: laboratory testing resources in integrative medicine.
With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery.Setting the stage for subsequent material, the firs
Do Not Go Gentle, first published in 1960, is a poignant novel about the U.S. Marines in World War II. The book focuses on Norman MacLeod, growing up in the tough Depression-era town of Butte, Montana. After his father succumbs to a mining-related disease, young Norman leaves school and also begins working in the copper mines. Following the death of his closest friend in an mine accident and the moving of his mother and sister to relatives back East, Norman enlists in the Marines. The book follows MacLeod through boot camp, life on and off base, and then to the South Pacific where MacLeod and his fellow Marines face both their fears and the Japanese. On leave in the U.S., Norm visits the wife of a killed comrade, and begins a relationship with her. Filled with gritty scenes and no-holds-barred dialog, Do Not Go Gentle remains a minor classic in the field of novels about men at war.
This book is written to break the greatest deception the devil (or adversary of God) has ever accomplished among Christians and nations. The devil is known as the Deceiver of Nations. KJV Revelation 12: And the great dragon was cast out, that old serpent, called the Devil, and Satan, which deceiveth the whole world: he was cast out into the earth, and his angels were cast out with him. This specific deception has been missed by every nation. The devil (adversary of God) worked this deception with his usual intent. KJV John 10: The thief cometh not, but for to steal, and to kill, and to destroy: I am come that they might have life, and that they might have it more abundantly. The devils MO or Mode of Operation is to steal, kill and destroy. It was his intent to hide the Eleventh Commandment, just so he (the devil), could steal, kill, and destroy God-kind. But God came that you might have life and have it more abundantly. Which would you rather have? Did you know that if you a leader of the church you will be responsible for breaking commandments of God (Exodus 32)? This is call to break the deception devil has woven. My impression from the Lord is over a Billion souls at stake. There are over a Billion souls both in the churches and still lost that this can and will affect.
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