David M. Pollock's Books

Endothelin in the Kidney

By: David M. Pollock,Erika I. Boesen

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The discovery of a potent vasoconstrictor, endothelin (ET)-1, derived from vascular endothelial cells was among a variety of key lines of investigation that helped to fuel a major explosion of studies related to endothelial cell biology. This was particularly evident within the pharmaceutical industry where receptor antagonists were quickly developed and are now on the market for treatment of pulmonary hypertension and in development for other diseases such as diabetic nephropathy and cancer. Importantly, we know that the kidney contains the highest level of ET-1 production and receptor expression in the body where it has been demonstrated to function as a pro-natriuretic autocrine and paracrine factor that is activated in conditions of high salt intake. This eBook provides a review of the various mechanisms whereby ET-1 has been shown to function within the kidney through a wide range of actions that include direct effects on tubular transport, intrarenal hemodynamics, as well as neural and endocrine functions. Much has yet to be discerned, but it is clear that the ET system is a major physiological regulator of fluid-electrolyte balance and blood pressure through these renal actions. Table of Contents: Discovery of Endothelin / Basic Biology of the Endothelin System / Renal Localization / Renal Hemodynamics / Renal Tubular Actions of Endothelin / Endothelin in Neural Modulation of Renal Function / Physiological Role of Endothelin / Endothelin in Renal Pathology / References / Author Biographies

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Morgan & Claypool Publishers

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ISBN 10

1615042105

ISBN 13

9781615042104

Science in the Romantic Era

By: David Knight

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Science in the Romantic Era

By: David Knight

First published in 1998. The Romantic Era was a time when society, religion and other beliefs, and science were all in flux. The idea that the universe was a great clock, and that men were little clocks, all built by a divine watchmaker, was giving way to a more dynamic and pantheistic way of thinking. A new language was invented for chemistry, replacing metaphor with algebra; and scientific illustration came to play the role of a visual language, deeply involved with theory. A scientific community came gradually into being as the 19th century wore on. The papers which compose this book have appeared in a wide range of books and journals; together with the new introduction they illuminate science and its context in the Romantic Era and follow its effects in the 19th century.

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401

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Routledge

Published Date

ISBN 10

1317242181

ISBN 13

9781317242185

Speaking to power

Advocacy for health and social care

By: Donnison, David

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Speaking to power

Advocacy for health and social care

By: Donnison, David

Anyone working, or planning to work, as an advocate for people who need help in dealing with public services will want to read this book. Advocacy is an area of increasing importance in service provision, where new ways of working have to be found that increasingly create an enabling, rather than a providing, state. Advocacy has an important part to play in this shift. Based on the experience of real advocates, Speaking to power is written in a vivid, jargon-free style. As well as practical chapters on 'what advocates do', using case studies from Scotland where important developments are taking place, the book discusses how advocacy fits into the broader scheme of things. Donnison describes and discusses examples of advocacy, with chapters dealing with management, training and evaluation of the work. The book concludes with a thought-provoking discussion of various strategies which help vulnerable people speak to power on more equal terms. Speaking to power will be particularly helpful to advocates working with people who have mental health or learning difficulties, for doctors, nurses and social workers involved in advocacy, and for students preparing to enter those professions. It will also be of interest to students of social policy and other readers concerned about Britain's broader social and political development.

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177

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Policy Press

Published Date

ISBN 10

184742743X

ISBN 13

9781847427434

A Companion to the Physical Sciences

By: David Knight

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A Companion to the Physical Sciences

By: David Knight

First published in 1989, this dictionary of the whole field of the physical sciences is an invaluable guide through the changing terminology and practices of scientific research. Arranged alphabetically, it traces how the meaning of scientific terms have changed over time. It covers a wide range of topics including voyages, observations, magnetism and pendulums, and central subjects such as atom, valency and energy. There are also entries on more abstract terms such as hypothesis, theory, induction, deduction, falsification and paradigm, emphasizing that while science is more than ‘organized common sense’ it is not completely different from other activities. Science’s lack of innocence is also recognized in headings like pollution and weapons. This book will be a useful resource to students interested in the history of science.

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184

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Routledge

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ISBN 10

1317244141

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9781317244141

Teaching Primary English

Subject Knowledge and Classroom Practice

By: Eve Bearne,David Reedy

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Teaching Primary English

Subject Knowledge and Classroom Practice

By: Eve Bearne,David Reedy

Now in its second edition, Teaching Primary English is a bestselling, comprehensive, evidence-informed guide designed to support and inspire teaching and learning in the primary school. Written in a clear and accessible way, it draws on the very latest research and theory to describe and exemplify a full and rich English curriculum. It offers those on teacher training courses, as well as qualified teachers who are looking to develop their practice, invaluable subject knowledge and guidance for effective, enjoyable classroom practice. Throughout there is an emphasis on equity and inclusion. Advice and ideas are supported by explicit examples of good teaching linked to video clips filmed in real schools, reflective activities, observational tasks and online resources. Each chapter includes suggestions for great children’s literature, considers assessment throughout and offers support in planning for inclusion and special educational needs. New and expanded areas for this edition include: Multimodal texts Increased coverage of Early Years Dialogic learning and oracy Comprehensive companion website with revised and additional resources A new section on digital literacies Reading for pleasure Teaching grammar in context Critical literacy With a focus on connecting all modes of English, the global and the local, and home and school experience, this detailed, uplifting book, includes inspiring case studies throughout and will support you in developing a curious, critical approach to teaching and learning English. Additional content can be found on the fantastic supporting website. Features include: Video clips from within the classroom to demonstrate English teaching techniques Audio resources, including an interactive quiz, to check understanding and provide real-life examples and case studies Downloadable resources to support teaching and incorporate into lesson plans.

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656

Publisher

Taylor & Francis

Published Date

ISBN 10

1000887421

ISBN 13

9781000887426

Preparing For Pandemics: Lessons From The Global Financial Crisis And Covid-19

By: David Longworth,Frank Milne

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Preparing For Pandemics: Lessons From The Global Financial Crisis And Covid-19

By: David Longworth,Frank Milne

In far too many cases, recommendations of forensic reports on previous pandemics were ignored. Substantial weaknesses in the preparation by public health authorities and governments increased the health and economic costs of the COVID-19 pandemic relative to what they would have been if pre-existing recommendations had been followed and a wider set of plans had been put into place. We discuss parallels between the lack of preparation of financial system regulators prior to the global financial crisis and the lack of preparation by public health authorities and governments prior to COVID-19. These parallels relate to: required stocks (of capital or equipment), data collection and sharing, lending facilities, stress testing and war games, early warning indicators and systems, contagion from abroad, operational risks, a system-wide approach (including effects on the real economy), models incorporating the heterogeneity of individuals, and effects on less-regulated parts of the system. The recent COVID-19 crisis has demonstrated that, apart from the direct economic consequences from illness and death from the virus, the main costs have been due to the varying degrees of preventative measures taken by the public, firms, and governments that directly impacted health, as well as social, economic, and financial activity. We make recommendations for carrying out post mortems on the COVID-19 experience, planning for future pandemics, and establishing transparent and accountable governance systems. We then propose the use of regular, combined health, economic, and financial stress tests and exercises/war games in preparing for future pandemics and other major environmental shocks.

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196

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World Scientific

Published Date

ISBN 10

9811255946

ISBN 13

9789811255946

Police in a Multicultural Society

An American Story, Second Edition

By: David E. Barlow,Melissa Hickman Barlow

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Police in a Multicultural Society

An American Story, Second Edition

By: David E. Barlow,Melissa Hickman Barlow

Social, political, and economic relationships played key roles in the historical development of the police. The authors present policing strategies from the vantage points of marginalized communities and emphasize the intersection of attitudes about class, race/ethnicity, gender, and sexual orientation with policies. Police practices cannot be class neutral in a class society, nor can they be race neutral or gender neutral in a racist, sexist, and heterosexist society. The key to understanding the relationship between the police and society is to think critically about the role of power and interests. The second edition includes a new chapter in the section on the police and rebellion covering recent events. There is also a new chapter on Latino/a police officers and an expanded chapter on LGBTQ police officers. Without meaningful social change toward greater justice, police reforms such as community policing and training in cultural diversity will fall short of creating an institution characterized by fairness and equality for all members of society. A clear view of history is essential for understanding the challenges a more diverse police force faces in today’s multicultural environment.

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511

Publisher

Waveland Press

Published Date

ISBN 10

1478637382

ISBN 13

9781478637387

Development

The Molecular Genetic Approach

By: Vincenzo E.A. Russo,Stuart Brody,David Cove,Sergio Ottolenghi

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Development

The Molecular Genetic Approach

By: Vincenzo E.A. Russo,Stuart Brody,David Cove,Sergio Ottolenghi

As a result of the molecular genetic analysis of development similar mechanisms for the regulation of gene expression are found in a wide range of organisms. In "Development - the Molecular Genetic Approach" these common mechanisms as well as the specific events leading to a differentiated cell are described. Particular items treated are, for example, how asymmetry is achieved, how cell size is determined, how cell division is controlled, how cell lineage influences development, how cells know their position, and how cells communicate during development.

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633

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Springer Science & Business Media

Published Date

ISBN 10

3642770436

ISBN 13

9783642770432

Care of the Jaundiced Neonate

By: David K. Stevenson,M. Jeffrey Maisels,Jon F. Watchko

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Care of the Jaundiced Neonate

By: David K. Stevenson,M. Jeffrey Maisels,Jon F. Watchko

A complete, authoritative guide to the management and treatment of neonatal jaundice Care of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field’s most respected neonatal care experts, the book uniquely explains how the imbalance between bilirubin production and elimination leads to jaundice—and that hazardous levels of unconjugated bilirubin can cause kernicterus, or brain damage. In addition, you’ll find the most current and clinically relevant perspectives on the physiology, genetics, and treatment of neonatal jaundice and related hemolytic conditions. FEATURES Covers all aspects of neonatal jaundice—from the biochemistry of bilirubin production to kernicterus Begins with an in-depth examination of the complex gene-environment interactions of bilirubin-induced neurotoxicity and its role in neonatal jaundice Surveys bilirubin production and measurement, its various fractions, and the metabolism and transport of bilirubin Selected chapters highlight the physiology and epidemiology of neonatal unconjugated hyperbilirubinemia; bilirubin toxicity; prevention, screening, and postnatal management; phototherapy and other treatments; and prevention-related public policy. Concluding chapter provides an overview of the key issues surrounding the incidence of neonatal jaundice in low-middle income countries Includes informative review of risk assessment and treatment with phototherapy and other modalities provide key approaches to the effective clinical management of neonatal hyperbilirubinemia

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301

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McGraw Hill Professional

Published Date

ISBN 10

0071762892

ISBN 13

9780071762892

Handbook of Crime Correlates

By: Lee Ellis,David P. Farrington,Anthony W. Hoskin

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Handbook of Crime Correlates

By: Lee Ellis,David P. Farrington,Anthony W. Hoskin

The Handbook of Crime Correlates, Second Edition summarizes more than a century of worldwide research on traits and social conditions associated with criminality and antisocial behavior. Findings are provided in tabular form, enabling readers to determine at a glance the nature of each association. Within each table, results are listed by country, type of crime (or other forms of antisocial behavior), and whether each variable is positively, negatively, or insignificantly associated with offending behavior. Criminal behavior is broken down according to major categories, including violent crime, property crime, drug offenses, sex offenses, delinquency, and recidivism. This book provides a resource for practitioners and academics who are interested in criminal and antisocial behavior. It is relevant to the fields of criminology/criminal justice, sociology, and psychology. No other publication provides as much information about how a wide range of variables—e.g., gender, religion, personality traits, weapons access, alcohol and drug use, social status, geography, and seasonality—correlate with offending behavior. - Includes 600+ tables regarding variables related to criminal behavior - Consolidates 100+ years of academic research on criminal behavior - Findings are identified by country and world regions for easy comparison - Lists criminal-related behaviors according to major categories - Identifies universal crime correlates

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732

Publisher

Academic Press

Published Date

ISBN 10

0128044772

ISBN 13

9780128044773

Hubris: The Road to Donald Trump

Power, Populism, Narcissism

By: David Owen

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Hubris: The Road to Donald Trump

Power, Populism, Narcissism

By: David Owen

In Hubris: The Road to Donald Trump, David Owen analyses and describes the mental and physical condition of US Presidents and UK Prime Ministers with a particular view that what went before paved the way to President Trump. Of recent leaders there have been alcoholics, depressives, narcissists, populists and those affected by hubris syndrome and driven by their religious beliefs.

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184

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Methuen

Published Date

ISBN 10

0413778401

ISBN 13

9780413778406

Free Radicals and Inflammation

By: Paul G. Winyard,David R. Blake,C. H. Evans

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Free Radicals and Inflammation

By: Paul G. Winyard,David R. Blake,C. H. Evans

The book deals with the role of both oxygen- and nitrogen-centred free radicals in inflammatory diseases such as rheumatoid arthritis. The well-known involvement of the superoxide anion radical in the bactericidal action of inflammatory cells suggests that radicals and the inflammatory response are inextricably linked. The widespread involvement of radicals in human disease seems inevitable, because inflammation is such a conspicuous component of human disease. For the first time, the present text integrates contributions from leading research groups who have been investigating the role of radicals within the context of all stages of inflammtion, such as the recruitment of inflammatory cells, their bactericidal action, inflammatory tissue destruction and inflammatory cell death by apoptosis. The chapters are broadly organised so that they trace the clinical course of the acute and chronic inflammtory response, emphasising the therapeutic implications of recent data on the contribution of nitric oxide and related nitrogen-centred species. The book will be of interest to academic and industrial researchers and clinicians with interests in the fields of inflammation or free radical biology.

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280

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Springer Science & Business Media

Published Date

ISBN 10

3764358513

ISBN 13

9783764358518

Fundamentals of Clinical Trials

By: Lawrence M. Friedman,Curt D. Furberg,David L. DeMets,David M. Reboussin,Christopher B. Granger

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Fundamentals of Clinical Trials

By: Lawrence M. Friedman,Curt D. Furberg,David L. DeMets,David M. Reboussin,Christopher B. Granger

This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.

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563

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Springer

Published Date

ISBN 10

331918539X

ISBN 13

9783319185392

Schwartz's Principles of Surgery, 10th edition

By: F. Charles Brunicardi,Dana K. Andersen,Timothy R. Billiar,David L. Dunn,John G. Hunter,Jeffrey B. Matthews,Raphael E. Pollock

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Schwartz's Principles of Surgery, 10th edition

By: F. Charles Brunicardi,Dana K. Andersen,Timothy R. Billiar,David L. Dunn,John G. Hunter,Jeffrey B. Matthews,Raphael E. Pollock

THE WORLD'S #1 SURGERY TEXT--UPDATED TO INCLUDE STATE-OF-THE-ART EVIDENCE-BASED SURGICAL CARE AND LEADERSHIP GUIDANCE FOR TRAINEES AND PRACTICING SURGEONS The Tenth Edition of Schwartz's Principles of Surgery maintains the book's unmatched coverage of the foundations of surgery while bringing into sharper focus new and emerging technologies. We have entered a new era of surgery in which minimally invasive surgery, robotic surgery, and the use of computers and genomic information have improved the outcomes and quality of life for patients. With these advances in mind, all chapters have been updated with an emphasis on evidence-based, state-of-the-art surgical care. An exciting new chapter, "Fundamental Principles of Leadership Training in Surgery," expands the scope of the book beyond the operating room to encompass the actual development of surgeons. This edition is also enriched by an increased number of international chapter authors and a new chapter on Global Surgery. More than ever, Schwartz's Principles of Surgery is international in scope--a compendium of the knowledge and technique of the world's leading surgeons. Features More clinically relevant than ever, with emphasis on high-yield discussion of diagnosis and treatment of surgical disease, arranged by organ system and surgical specialty Content is supported by boxed key points, detailed anatomical figures, diagnostic and management algorithms, and key references Beautiful full-color design

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2098

Publisher

McGraw Hill Professional

Published Date

ISBN 10

0071800921

ISBN 13

9780071800921

Nathan and Oski's Hematology of Infancy and Childhood

By: Stuart H. Orkin,David G. Nathan

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Nathan and Oski's Hematology of Infancy and Childhood

By: Stuart H. Orkin,David G. Nathan

To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you'll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski's Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. And, as an Expert Consult title, this thoroughly updated 7th edition comes with access to the complete contents online, fully searchable. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need. Provides access to the complete contents online, fully searchable, enabling you to consult it rapidly from any computer with an Internet connection. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

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1868

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1416034307

ISBN 13

9781416034308

BIOS Instant Notes in Human Physiology

By: Daniel McLaughlin,Jonathan Stamford,David White

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BIOS Instant Notes in Human Physiology

By: Daniel McLaughlin,Jonathan Stamford,David White

Instant Notes in Human Physiology will be valuable to students in whatever context they are studying physiology. It explains fundamental concepts and the major physiological systems, showing how they are integrated, without overloading the reader with information.

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