David M. Jacobson's Books

Fundamentals of Industrial Problem Solving

A Practitioner's Guide

By: David M. Jacobson,Dana Livingston,J.P. Chauvel,Zdravko I. Stefanov,Eldad Herceg,Carla Schmidt,Sunil Kumar Chaudhary,Christopher Paul Christenson

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Fundamentals of Industrial Problem Solving

A Practitioner's Guide

By: David M. Jacobson,Dana Livingston,J.P. Chauvel,Zdravko I. Stefanov,Eldad Herceg,Carla Schmidt,Sunil Kumar Chaudhary,Christopher Paul Christenson

Teaches Readers How to Apply a Structured Problem-Solving Methodology for Industrial Fields Based on Sound Scientific Principles As modern industrial processes have become increasingly complex, complicated multi-factor problems have emerged. These complex problems end up costing companies millions of dollars every day. Existing problem-solving techniques are only effective to a certain point. This book provides a solution to a myriad of industrial problems by using first principles and rigorous hypothesis testing. Key topics covered within the work include: How to use the latest research, advanced modeling, big data mining, analytical testing, and many other techniques to systematically create and test hypotheses surrounding why a process is malfunctioning How to use scenario development to frame a team’s understanding of why a process is malfunctioning How to approach today’s lack of experienced industrial workers, whose failure to approach problem solving from first fundamentals are causing myriad of inefficiencies in industry How to use multiple methodologies together with an emphasis on first principles and mechanistic math modeling as a basis to industrial problem solving Engineers of any discipline working in both research and development of manufacturing environments, along with professionals in any industrial discipline looking to reduce costs will be able to use this work to both understand and pragmatically solve the pressing issues we see in today’s industrial market.

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Page Count

412

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119543193

ISBN 13

9781119543190

The 7 1/2 Habits of Highly Humorous People

By: David M. Jacobson

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The 7 1/2 Habits of Highly Humorous People

By: David M. Jacobson

The 7 1/2 Habits of Highly Humorous People" is an easy and fun book to read. The practical applications on how to improve your sense of humor make this a 'keeper.' This book reveals the mysteries to improving your sense of humor to be happier, healthier, have better relationships and make you a highly humorous person. This funny, uplifting and endearing book will teach you the secrets of using humor to decrease stress, cope with adversity and enhance the good times. It tells the story of one man's rise from the depths of illness and chronic pain to the heights of success attributable to his daily humor habits. He explains his discovery of how the simple use of HUMOR can transform your life and the world you live in. This book begins your journey of enhancing your Humor Horizons. James Brown "felt good," and so will you when you read this book and change the course of your life.

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Page Count

110

Publisher

David Jacobson

Published Date

ISBN 10

1602640378

ISBN 13

9781602640375

The Hellenistic Paintings of Marisa

By: David M. Jacobson

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The Hellenistic Paintings of Marisa

By: David M. Jacobson

In early June 1902, John Peters, an American theologian, and Hermann Thiersch, a German classical scholar, were alerted to the discovery of two painted burial caves at Marisa/Beit Jibrin, less than 40 miles (62 km) by road southwest from Jerusalem. Tomb robbers had, a short time previously, forced their way into the burial chambers and caused damage to their fabric. Realising that these splendid tombs dated to about 200 BCE and the importance of their painted interiors, the two scholars immediately commissioned a leading Jerusalem photographer, Chalil Raad, to record them. This was fortunate, because the paintings on the soft limestone walls rapidly deteriorated and now can no longer be seen. Peters and Thiersch published a monograph on the painted tombs, illustrated with hand-drawn copies of the photographs, but the original plates have lain all these years in the archives of the Palestine Exploration Fund in London, unpublished. The paintings are unique in the Greek pictorial repertoire and are among the most important surviving examples of Ptolemaic art. The remarkable painted frieze extending along the two long sides of the main chamber of Tomb I depicts 22 different animal species, drawn from the wild fauna of the Levant, the Nile basin and the Horn of Africa - as well as a few mythical beasts. This animal frieze attests to the interest in exotic animals shown in the Hellenistic period. Other remarkable subjects represented in the Marisa paintings include Cerberus, the three-headed guard-dog of Hades, and a pair of elegant musicians in Greek dress. Timed to coincide with the centenary of the discovery of the painted tombs, a new study on the paintings has been produced by David Jacobson. This study appears as Annual VII of the Palestine Exploration Fund. It contains, for the first time, high quality reproductions of the photographic plates taken in 1902, which are held in the PEF collections. Reproduced with the photographs are the proofs of the coloured lithographs, which are superior in quality to the versions that were published. The inaccuracies and loss of delicate detail of the originals in the coloured lithographs used by Peters and Thiersch for their 1905 publication are clearly apparent. The accompanying text includes an analysis of all the paintings in the light of a century of scholarship and an assessment is made of their religious and cultural significance. Each of the animals in the frieze is compared with descriptions given by ancient writers, and a new interpretation is presented of the cycle as a whole. An appraisal is made of the overall contribution of the Marisa paintings to our knowledge of the art and culture of the Levant in the Ptolemaic period. Included with this new study is facsimile reprint of the original 1905 publication, now long out of print, and it includes superior copies of the coloured lithographs from that edition. This new publication also reproduces a very rare addenda section prepared by R.A.S. Macalister after inspecting the Marisa tombs in October of that year.

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261

Publisher

Taylor & Francis

Published Date

ISBN 10

104028437X

ISBN 13

9781040284377

Critical Theory to Structuralism

Philosophy, Politics and the Human Sciences

By: David Ingram

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Critical Theory to Structuralism

Philosophy, Politics and the Human Sciences

By: David Ingram

Philosophy in the middle of the 20th Century, between 1920 and 1968, responded to the cataclysmic events of the time. Thinkers on the Right turned to authoritarian forms of nationalism in search of stable forms of collective identity, will, and purpose. Thinkers on the Left promoted egalitarian forms of humanism under the banner of international communism. Others saw these opposed tendencies as converging in the extinction of the individual and sought to retrieve the ideals of the Enlightenment in ways that critically acknowledged the contradictions of a liberal democracy racked by class, cultural, and racial conflict. Key figures and movements discussed in this volume include Schmitt, Adorno and the Frankfurt School, Arendt, Benjamin, Bataille, French Marxism, Black Existentialism, Saussure and Structuralism, Levi Strauss, Lacan and Late Pragmatism. These individuals and schools of thought responded to this 'modernity crisis' in different ways, but largely focused on what they perceived to be liberal democracy's betrayal of its own rationalist ideals of freedom, equality, and fraternity.

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Page Count

382

Publisher

Routledge

Published Date

ISBN 10

1317546865

ISBN 13

9781317546863

Braddom's Physical Medicine and Rehabilitation E-Book

By: David X. Cifu

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Braddom's Physical Medicine and Rehabilitation E-Book

By: David X. Cifu

Thoroughly updated to reflect the latest advances and technologies, Braddom's Physical Medicine and Rehabilitation, 6th Edition, remains the market leader in the field of PM&R. For more than 20 years, this bestselling reference has been the go-to resource for the entire rehabilitation team, providing in-depth coverage of essential core principles along with the latest research, technologies, and procedures that enhance patient care and facilitate optimal return to function. In this edition, lead editor Dr. David X. Cifu and his team of expert associate editors and contributing authors employ a more succinct format that emphasizes need-to-know material, incorporating new key summary features, including high-yield information and study sheets for problem-based learning. - Focuses more heavily on rehabilitation, with case studies throughout and more comprehensive coverage of stroke evaluation, rehabilitation, and therapies. - Provides expanded information on key topics such as interventional pain management options, gait and prosthetics, USG, fluoroscopy, electrodiagnosis and more. - Features a new chapter on Occupational Medicine and Vocational Rehabilitation, plus enhanced coverage of the neurogenic bladder, rehabilitation and prosthetic restoration in upper limb amputation, and acute medical conditions including cardiac disease, medical frailty, and renal failure. - Discusses quality and outcome measures for medical rehabilitation, practical aspects of impairment rating and disability determination, integrative medicine in rehabilitation, and assistive technology. - Offers highly illustrated, templated chapters that are easy to navigate without sacrificing coverage of key topics. - Includes access to dozens of even more practical videos and hundreds of integrated self-assessment questions for more effective learning and retention. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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1395

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323625401

ISBN 13

9780323625401

Emerging Respiratory Infections in the 21st Century, An Issue of Infectious Disease Clinics

By: Alimuddin Zumla,Wing-Wai Yew,David S.C. Hui

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Emerging Respiratory Infections in the 21st Century, An Issue of Infectious Disease Clinics

By: Alimuddin Zumla,Wing-Wai Yew,David S.C. Hui

Respiratory infections are among the most common causes of morbidity and mortality worldwide. These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB. For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

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320

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Elsevier Health Sciences

Published Date

ISBN 10

145570038X

ISBN 13

9781455700387

Cerebrospinal Fluid in Clinical Practice

By: David N. Irani

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Cerebrospinal Fluid in Clinical Practice

By: David N. Irani

Given the evolution of cerebrospinal testing (CSF) testing methods, the near future is certain to see an explosion of new CSF analysis methodologies. Broad-based and extensively illustrated, Cerebrospinal Fluid in Clinical Practice provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. It examines the alterations of the composition of CSF in relation to diseases and disorders of the nervous system, emphasizing the findings that are useful in clinical practice. This expansive reference is perfect regardless of your level of experience in central nervous system diseases. Provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. Explores the gamut of all CNS infections for a broad but detailed review of the scope of neurological disease. Contains detailed discussion on the proper use of specific diagnostic screens on CSF, so you may gain knowledge on how new diagnostic methods impact clinical medicine. Incorporates extensive illustrations and tables, with visual emphasis on diagnostic, laboratory, and anatomic data.

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329

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Elsevier Health Sciences

Published Date

ISBN 10

1437710727

ISBN 13

9781437710724

Psychosis in the Elderly

By: Anne M. Hassett,David Ames,Edmond Chiu

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Psychosis in the Elderly

By: Anne M. Hassett,David Ames,Edmond Chiu

Across the spectrum of psychopathology in later life, psychotic symptomatology has been the most neglected, and although literature in this area is increasing, this is the first book to address the need for an overarching framework to examine and understand late-life psychotic phenomena. Exploring the practical and ethical issues that arise when ma

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278

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CRC Press

Published Date

ISBN 10

0203336984

ISBN 13

9780203336984

Carbon Sequestration for Climate Change Mitigation and Adaptation

By: David A. N. Ussiri,Rattan Lal

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Carbon Sequestration for Climate Change Mitigation and Adaptation

By: David A. N. Ussiri,Rattan Lal

This book provides an understanding of the role of human activities in accelerating change in global carbon cycling summarizes current knowledge of the contemporary carbon budget. Starting from the geological history, this volume follows a multidisciplinary approach to analyze the role of human activities in perturbing carbon cycling by quantifying changes in different reservoirs and fluxes of carbon with emphasis on the anthropogenic activities, especially after the industrial revolution. It covers the role of different mitigation options – natural ecological, engineered, and geoengineered processes as well as the emerging field of climate engineering in avoiding dangerous abrupt climate change. Although the targeted audience is the educators, students, researchers and scientific community, the simplified analysis and synthesis of current and up to date scientific literature makes the volume easier to understand and a tool policy makers can use to make an informed policy decisions.

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554

Publisher

Springer

Published Date

ISBN 10

3319538454

ISBN 13

9783319538457

Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

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Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics

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3211

Publisher

CRC Press

Published Date

ISBN 10

1444147528

ISBN 13

9781444147520

Student Handbook of Criminal Justice and Criminology

By: John Muncie,David Wilson

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Student Handbook of Criminal Justice and Criminology

By: John Muncie,David Wilson

Written by some of the leading criminologists in the country, this new title is a 'one-stop shop' for those who teach, study or are interested in criminology and the criminal justice systems of the UK.

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411

Publisher

Routledge

Published Date

ISBN 10

1135334331

ISBN 13

9781135334338

Art and Technology of Entertainment Computing and Communication

By: Adrian David Cheok

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Art and Technology of Entertainment Computing and Communication

By: Adrian David Cheok

Art and Technology of Entertainment Computing and Communication takes a blue sky research perspective on the field of interactive media for entertainment computing. Adrian David Cheok argues that entertainment as an end-product is useful for interactive play, however it is also a powerful tool for learning and communication and it is also a key driver for the development of information technology. This book explores the future of entertainment technologies used for communication and describes quantum step research. It will inform and inspire readers to create their own radical inventions and innovations that are not incremental, but which break through ideas and non-obvious solutions. One of the main explorations is the examination of how new forms of computer interaction can lead to radical new forms of technology and art for entertainment computing. Art and Technology of Entertainment Computing and Communication is an informative and inspirational text for students and the next generation of researchers. It’s main aim is to provide information that will hopefully help change the world and society for the better, through new modes of entertainment and communication. Academics, researchers, engineers, game designers, and interaction designers, will find the content both interesting and valuable. Entertainment is the "engine" to inspire people and drive innovation in interactive digital media design. The pioneer of the field, Prof. Adrian David Cheok, takes you on an exciting tour of the future shaped by the Entertainment Technologies. Hiroshi ISHII, Muriel R. Cooper Professor of Media Arts and Sciences, MIT Media Laboratory.

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299

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1849961379

ISBN 13

9781849961370

A Hole in the Wind

A Climate Scientist's Bicycle Journey Across the United States

By: David Goodrich

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A Hole in the Wind

A Climate Scientist's Bicycle Journey Across the United States

By: David Goodrich

An epic bicycle journey across the American hinterland that explores the challenges of climate change alongside a diverse array of American voices. After a distinguished career in climate science as the Director of the UN Global Climate Observing System in Geneva, David Goodrich returned home to the United States to find a nation and a people in denial. Concerned that the American people are willfully deluded by the misinformation about climate that dominates media and politics, David thought a little straight talk could set things right. As they say in Animal House, he decided that "this calls for a stupid and futile gesture on someone's part, and I'm just the guy to do it." Starting on the beach in Delaware, David rode his bike 4,200 miles to Oregon, talking with the people he met on the ultimate road trip. Along the way he learned a great deal about why climate is a complicated issue for many Americans and even more about the country we all share. Climate change is the central environmental issue of our time. But A Hole in the Wind is also about the people Dave met and the experiences he had along the way, like the toddler's beauty pageant in Delaware, the tornado in Missouri, rust-belt towns and their relationship with fracking, and the mined-out uranium ghost town in Wyoming. As he rides, David will discuss the climate with audiences varying from laboratories to diners to elementary schools. Beautifully simple, direct, and honest, A Hole in the Wind is a fresh, refreshing ride through a difficult and controversial topic, and a rich read that makes you glad to be alive.

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Page Count

327

Publisher

Simon and Schuster

Published Date

ISBN 10

1681774852

ISBN 13

9781681774855

Brain-Gut Interactions

By: Yvette Tache,David L. Wingate

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Brain-Gut Interactions

By: Yvette Tache,David L. Wingate

Brain-Gut Interactions serves as a reference source and stimulus for expanded research efforts aimed at unravelling the pathophysiology of brain-gut interactions. Within the general framework of brain-gut interactions, it covers the various areas in which this growing interdisciplinary field has evolved. Topics discussed in this volume include the topography and morphology of afferent and efferent connections between the gut and the medulla and hypothalamic nuclei, the role of afferent and efferent pathways in the regulation of gastrointestinal function, the brain's regulation of gastrointestinal secretory and motor function, and the function of peripheral and central cholecystokinin in the mechanisms of satiety. The final section of this book focuses on topics such as stress, emesis, visceral pain, and brain-related disorders of the intestine based on experimental and clinical data. Students and investigators working with brain-gut interactions, gastroenterologists, psychologists, and psychiatrists will find this book to be an essential reference resource.

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Page Count

400

Publisher

CRC Press

Published Date

ISBN 10

0849353688

ISBN 13

9780849353680

Plant Secondary Metabolism

By: David S. Seigler

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Plant Secondary Metabolism

By: David S. Seigler

Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.

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Page Count

766

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461549132

ISBN 13

9781461549130

Principles of Criminology

By: Edwin H. Sutherland,Donald R. Cressey,David F. Luckenbill

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Principles of Criminology

By: Edwin H. Sutherland,Donald R. Cressey,David F. Luckenbill

This classic has been the most authoritative text in the field since 1924. The thoroughly revised Eleventh Edition continues to provide a sound, sophisticated, sociological treatment of the principal issues in criminology.

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708

Publisher

AltaMira Press

Published Date

ISBN 10

0759117896

ISBN 13

9780759117891

Effects of Persistent and Bioactive Organic Pollutants on Human Health

By: David O. Carpenter

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Effects of Persistent and Bioactive Organic Pollutants on Human Health

By: David O. Carpenter

Examines what we know about the relationship between organic chemicals and human disease Organic chemicals are everywhere: in the air we breathe, the water we drink, and the food we eat. They are also found in a myriad of common household and personal care products. Unfortunately, exposure to some organic chemicals can result in adverse health effects, from growth and developmental disorders to cancer and neurodegenerative diseases. This book examines how organic chemicals affect human health. It looks at the different diseases as well as how individual organ systems are affected by organic chemicals. Effects of Persistent and Bioactive Organic Pollutants on Human Health begins with an introductory chapter explaining why we should care about organic chemicals and their effect on human health. Next, the authors address such important topics as: Burden of cancer from organic chemicals Organic chemicals and obesity Effects of organic chemicals on the male reproductive system Organic chemicals and the immune system Intellectual developmental disability syndromes and organic chemicals Mental illness and exposure to organic chemicals The book ends with an assessment of how much human disease is caused by organic chemicals. Chapters have been contributed by leading international experts in public and environmental health and are based on the latest research findings. Readers will find that all of the contributions are clear and easy to comprehend, with extensive references for further investigation of individual topics. Effects of Persistent and Bioactive Organic Pollutants on Human Health is recommended for students and professionals in medicine as well as public and environmental health, bringing them fully up to date with what we know about the relationship between organic chemicals and human health.

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485

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118679547

ISBN 13

9781118679548

Tumorigenesis Research Advances

By: David K. Wong

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Tumorigenesis Research Advances

By: David K. Wong

Tumourigenesis is the formation of tumours in the body, often caused by oncogenes. These tumours are the result of uncontrollable reproduction (cell division) due to alterations in the cell's genetic code, creating lesions in the tissue where they reside. Tumourigenesis can be divided into tumour initiation, promotion and progression. Oncogenomics often studies tumours caused by such a condition in hope of pinpointing genes -- pieces of genetic information -- that are susceptible to being changed (mutated) by external factors like ultraviolet light, toxic chemicals, and other carcinogens. The range of normal genetic alterations that a person's DNA undergoes over time is extraordinarily large, so it is hard to detect exactly what cause tumourigenesis. This book presents the latest research advances in the field.

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256

Publisher

Nova Publishers

Published Date

ISBN 10

1600218172

ISBN 13

9781600218170

Clinical Nuclear Medicine

By: K. E. Britton,David Collier,Michael Maisey,Q. H. Siraj

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Clinical Nuclear Medicine

By: K. E. Britton,David Collier,Michael Maisey,Q. H. Siraj

Nuclear medicine is the bridge between a particular clinical problem and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book to approach the subject from a clinical standpoint, including where necessary relevant physiological material. There exist many excellent texts which cover the basic science and technology of nuclear medicine. We have, therefore, severely limited our coverage of these aspects of the subject to matters which we felt to be essential, particularly those which have been less well covered in other texts - for example, the contents of Chapter 21 on Quantitation by Royal and McNeil. Similarly, we have included at the end of some chapters descriptions of particular techniques where we and the authors felt that it would be helpful. In order to emphasize the clinical approach of this book we have inverted the traditional sequence of material in chapters, presenting the clinical problems first in each instance.

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Page Count

757

Publisher

Springer

Published Date

ISBN 10

1489933565

ISBN 13

9781489933560

Software Design

Creating Solutions for Ill-Structured Problems

By: David Budgen

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Software Design

Creating Solutions for Ill-Structured Problems

By: David Budgen

Software Design: Creating Solutions for Ill-Structured Problems, Third Edition provides a balanced view of the many and varied software design practices used by practitioners. The book provides a general overview of software design within the context of software development and as a means of addressing ill-structured problems. The third edition has been expanded and reorganised to focus on the structure and process aspects of software design, including architectural issues, as well as design notations and models. It also describes a variety of different ways of creating design solutions such as plan-driven development, agile approaches, patterns, product lines, and other forms. Features •Includes an overview and review of representation forms used for modelling design solutions •Provides a concise review of design practices and how these relate to ideas about software architecture •Uses an evidence-informed basis for discussing design concepts and when their use is appropriate This book is suitable for undergraduate and graduate students taking courses on software engineering and software design, as well as for software engineers. Author David Budgen is a professor emeritus of software engineering at Durham University. His research interests include evidence-based software engineering (EBSE), software design, and healthcare informatics.

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Page Count

365

Publisher

CRC Press

Published Date

ISBN 10

1315300060

ISBN 13

9781315300061

Biochemistry

The Chemical Reactions Of Living Cells

By: David Metzler

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Biochemistry

The Chemical Reactions Of Living Cells

By: David Metzler

Biochemistry: The Chemical Reactions of Living Cells is a 16-chapter reference source on chemical structures and reactions of living cells. The first three chapters of this book contain introductory material on cell structure, molecular architecture, and energetic. The subsequent chapters examine the allosteric effect of the binding structures of oligomeric enzymes, microtubules, viruses, and muscle. These chapters also describe the structures and chemical properties of membranes and of the surrounding cell coats. The discussions then shift to the general properties of enzymes, the kinetics of chemical reactions, and the various mechanisms employed in enzymatic catalysis. Considerable chapters are devoted to the reaction sequences found in metabolism. These chapters particularly examine the carbohydrate and lipid metabolism; photosynthesis; and biosynthesis and catabolism of an enormous number of nitrogenous compounds. The final chapters highlight the genetic and hormonal control of metabolism, development, and brain function. Biochemistry teachers and students will find this book of great value.

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1165

Publisher

Elsevier

Published Date

ISBN 10

0323141749

ISBN 13

9780323141741

Fields Virology: DNA Viruses

By: Peter M. Howley,David M. Knipe,Jeffrey L. Cohen,Blossom A. Damania

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Fields Virology: DNA Viruses

By: Peter M. Howley,David M. Knipe,Jeffrey L. Cohen,Blossom A. Damania

Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.

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Page Count

2429

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

197511258X

ISBN 13

9781975112585

Understanding Contemporary Strategy

By: David J. Lonsdale,Thomas M. Kane

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Understanding Contemporary Strategy

By: David J. Lonsdale,Thomas M. Kane

Understanding Contemporary Strategy provides an accessible and comprehensive introduction to the theory and practice of modern strategy. Covering all the main issues in the field, the book explores the major themes through a combination of classical and modern strategic theory, history and current practice. The book is split into three main sections: Definition and Context : including discussion of the human, technological, intelligence, ethical and grand-strategic dimensions Strategy in the Geographic Environments: land, sea, air and space Contemporary Strategic Challenges: terrorism, insurgency and nuclear strategy. Each chapter presents the reader with a succinct summary of the topic, but also provides a challenging analysis of current issues, supporting students with pedagogical features such as suggested further reading, boxed case studies and study questions. This book will be essential reading for upper-level students of strategic studies, war studies, military history and international security.

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381

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Routledge

Published Date

ISBN 10

1136622802

ISBN 13

9781136622809

Antineoplastic and Immunosuppressive Agents

Part II

By: Alan C. Sartorelli,David G. Johns

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Antineoplastic and Immunosuppressive Agents

Part II

By: Alan C. Sartorelli,David G. Johns

Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of established agents has continued to expand, and has permitted rational drug design to play a significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.

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1100

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642658067

ISBN 13

9783642658068

Managing the Drug Discovery Process

Insights and advice for students, educators, and practitioners

By: Susan Miller,Walter Moos,Barbara Munk,Stephen Munk,Charles Hart,David Spellmeyer

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Managing the Drug Discovery Process

Insights and advice for students, educators, and practitioners

By: Susan Miller,Walter Moos,Barbara Munk,Stephen Munk,Charles Hart,David Spellmeyer

Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters

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684

Publisher

Elsevier

Published Date

ISBN 10

0128243058

ISBN 13

9780128243053

Practical Toxicology

Evaluation, Prediction, and Risk, Third Edition

By: David Woolley,Adam Woolley

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Practical Toxicology

Evaluation, Prediction, and Risk, Third Edition

By: David Woolley,Adam Woolley

Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.

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553

Publisher

CRC Press

Published Date

ISBN 10

1498709303

ISBN 13

9781498709309

The Oxford Textbook on Criminology

By: Steve Case,David Manlow,Kate Williams,Philip Johnson,Roger Smith

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The Oxford Textbook on Criminology

By: Steve Case,David Manlow,Kate Williams,Philip Johnson,Roger Smith

First published in 2017, as: Criminology.

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1129

Publisher

Oxford University Press

Published Date

ISBN 10

0198835833

ISBN 13

9780198835837

Agrippa II

The Last of the Herods

By: David Jacobson

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Agrippa II

The Last of the Herods

By: David Jacobson

Agrippa II is the first comprehensive biography of the last descendant of Herod the Great to rule as a client king of Rome. Agrippa was the last king to assume responsibility for the management of the Temple in Jerusalem, and he ultimately saw its destruction in the Judaean-Roman War. This study documents his life from a childhood spent at the Imperial court in Rome and rise to the position of client king of Rome under Claudius and Nero. It examines his role in the War during which he sided with Rome, and offers fresh insights into his failure to intervene to prevent the destruction of Jerusalem and its Sanctuary, as well as reviewing Agrippa’s encounter with nascent Christianity through his famous interview with the Apostle Paul. Also addressed is the vexed question of the obscurity into which Agrippa II has fallen, in sharp contrast with his sister Berenice, whose intimate relationship with Titus, the heir to the Roman throne, has fired the imagination of writers through the ages. This study also includes appendices surveying the coins issued in the name of Agrippa II and the inscriptions from his reign. This volume will appeal to anyone studying Judaean-Roman relations and the Judaean-Roman War, as well as those working more broadly on Roman client kingship, and Rome’s eastern provinces. It covers topics that continue to attract general interest as well as stirring current scholarly debate. Maps 1 and 2 available in colour at www.routledge.com/9781138331815

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280

Publisher

Routledge

Published Date

ISBN 10

0429823576

ISBN 13

9780429823572

Introduction to Policing

By: Steven M. Cox,David Massey,Connie M. Koski,Ericka Wentz

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Introduction to Policing

By: Steven M. Cox,David Massey,Connie M. Koski,Ericka Wentz

Written by an author team that includes former and current law enforcement officers, Introduction to Policing focuses on the most thought-provoking, contemporary issues in the world of policing. The authors tackle complex issues that impact policing today, such as social diversity; advancements in technology; and global issues, such as terrorism and transnational organized crime. The Fifth Edition offers fully updated content in SAGE’s Vantage courseware platform. This title is accompanied by a complete teaching and learning package. Contact your SAGE representative to request a demo. Learning Platform / Courseware SAGE Vantage is an intuitive learning platform that integrates quality SAGE textbook content with assignable multimedia activities and auto-graded assessments to drive student engagement and ensure accountability. Unparalleled in its ease of use and built for dynamic teaching and learning, Vantage offers customizable LMS integration and best-in-class support. It’s a learning platform you and your students will actually love. Learn more. Assignable Video with Assessment Assignable video (available in SAGE Vantage) is tied to learning objectives and curated exclusively for this text to bring concepts to life. Watch a sample video now. LMS Cartridge: Import this title’s instructor resources into your school’s learning management system (LMS) and save time. Don’t use an LMS? You can still access all of the same online resources for this title via the password-protected Instructor Resource Site. Learn more.

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485

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SAGE Publications

Published Date

ISBN 10

1071838164

ISBN 13

9781071838167

The Archaeology of Daily Life

Ordinary Persons in Late Second Temple Israel

By: David A. Fiensy

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The Archaeology of Daily Life

Ordinary Persons in Late Second Temple Israel

By: David A. Fiensy

Have you ever wondered what it was like to live in the past? Did they experience reality in a much different way than we do now with our media, our fast travel, our fast food, and our leisure? Do you especially think about what it might have been like to have lived in Bible times? What would your childhood have been like? How would you have chosen a marriage partner? How would you probably have made a living? What sort of house would you have lived in? What diseases would have threatened your daily existence? How long would you have lived? How would you have practiced your religion? These are a few of the intriguing questions answered by this study. The book takes you on a journey into the past to view daily life through the lenses of not only texts but archaeological finds. The information from the past is also filtered through ethnographic studies of more contemporaneous, yet traditional, societies in the Middle East. The result is a presentation that may surprise you--even shock you--at times, but always will interest you.

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330

Publisher

Wipf and Stock Publishers

Published Date

ISBN 10

1532673094

ISBN 13

9781532673092

Book's by David M. Jacobson

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