This volume offers a comprehensive history of the Mount Desert Island Biological Laboratory (MDIBL), one of the major marine laboratories in the United States and a leader in using marine organisms to study fundamental physiological concepts. Beginning with its founding as the Harpswell Laboratory of Tufts University in 1898, David H. Evans follows its evolution from a teaching facility to a research center for distinguished renal and epithelial physiologists. He also describes how it became the site of major advances in cytokinesis, regeneration, cardiac and vascular physiology, hepatic physiology, endocrinology and toxicology, as well as studies of the comparative physiology of marine organisms. Fundamental physiological concepts in the context of the discoveries made at the MDIBL are explained and the social and administrative history of this renowned facility is described.
Personality, psychopathology and emotional factors are intimately related to smoking, yet there are few efforts to integrate relevant findings in these areas. Taking a comprehensive, current and detailed view, this text develops an empirically-based model that reflects the multi-dimensional, individual-difference-related causal paths associated with smoking and its reinforcing and affect-modulating effects.; Starting with a review of models of smoking motivation, this volume then goes on to discuss effect and emotion, and the nature, biological bias and relationships among personality, temperament and psychopathology. Other chapters focus attention on questions of when, in whom and what mechanisms promote and reinforce smoking and tobacco use such as gender differences. Utilising the findings of these chapters, the integrative biopsychosocial STAR Model Of Smoking Effects And Motivation Is Presented And Its Implications are examined.; As the percentage of smokers in the general population decreases, a growing number of those continuing to smoke will be even more difficult to reach. Such individuals will benefit from the individualised and intensive interventions suggested here. This text is intended to be of use to psychologists, psychiatrists, physicians, epidemiologists, sociologists and other health professionals.
Analysis and insights from top thought leaders on a pivotal topic in investing and asset management Valuation is the cornerstone for investment analysis, and a thorough understanding and correct application of valuation methodologies are critical for long-term investing success. Edited by two leading valuation experts from CFA Institute, this book brings together the insights and expertise of some of the most astute and successful investment minds of the past 50 years. From Benjamin Graham, the “father of value investing,” to Aswath Damodaran, you’ll learn what these investment luminaries have to say about investment valuation techniques, including earnings and cash flow analysis. Features the best thinking on valuation from the industry’s masters on the topic, supplemented with dozens of fascinating and instructive real-world examples Comprehensively discusses special valuation situations, such as real options, employee stock options, highly leveraged firms, corporate takeovers, and more Supplies you with the tools you need to successfully navigate and thrive in the ever-changing financial markets Is being produced with the full support and input of CFA Institute, the world’s leading association of investment professionals
Although E. coli is primarily a commensal of mammals, and to a lesser extent birds, it can be isolated from a variety of host species as well as soil, sediments, and water. It has long been recognized that E. coli exhibits quite extensive substructuring and that the relative abundance of the most common phylo-groups varies with respect to host age and sex, host species, as well as geographical location. Strains belonging to some phylo-groups are much more frequently encountered in water samples than strains belonging to other phylo-groups. The extent to which strain survival in the external environment has determined the evolutionary origins of the various diarrheal pathotypes is unknown. There is a growing body of evidence that indicates commensal E. coli, like the diarrheal pathotypes, exhibits at some tissue specificity within the gastrointestinal tract. However, there is little evidence to suggest that commensal E. coli exhibit extensive host specificity as is the case with many of the diarrheal pathotypes.
The volume offers essential reading for undergraduates who need an introduction to the field, for graduate students who wish to broaden their understanding of stratification research, and for advanced scholars who seek a basic reference guide. Although most of the selections are middle-range theoretical pieces suitable for introductory courses, the anthology also includes advanced contributions on the cutting edge of research. The editor outlines a modified study plan for undergraduate students requiring a basic introduction to the field.
This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.
This critique of Reaganomics attempts to provide alternatives to both the supply experiments of the 1980s and neoliberal strategies of austerity. It presents arguments for economic democracy with a worker-oriented blueprint for improving productivity, growth, employment and economic justice.
In Beyond the Wasteland three highly respected economists trace the causes of America's declining productivity, show how the accepted economic prescriptions fail to address the central crises of the system, and propose a programme for a fully democratic reform designed to regenerate the world economy . English readers will find the analysis highly relevant to their own situation.
Since the early 1980s, economic experts have recommended "downsizing" as the best way for U.S. corporations to remain competitive. Reducing unnecessary staff would lower costs, increase profits, and transform these companies into lean, mean production machines. As many American businesses pursued this strategy—often in the wake of mergers and acquisitions that left them with an unwieldy layer of middle management—and raised their bottom line, it seemed the experts were right. Yet as David M. Gordon shows in this iconoclastic book, most of them have really only gone halfway. They are "mean," but far from lean. Tracing the overall employment patterns of the past decade, Gordon shows that most American companies actually employ more managers and supervisors than ever before. These ever-increasing functionaries control company payrolls and pay themselves generous salaries—at the expense of average workers. For despite a steadily growing economy the real wages of the American worker have been falling for the past 20 years. To explain this decline and the much-debated "wage gap" that resulted, pundits and professors invoke various causes ranging from the flow of production jobs overseas to the average worker's lack of the technological skills needed in today's "knowledge economy." But Gordon exposes the single greatest factor in this decline, a corporate strategy that penalizes line workers and hinders businesses from competing effectively in world markets: the simultaneous overstaffing of management hierarchies and the inadequate compensation of workers. Instead of sharing profits with their employees, thus encouraging them to work harder, management has more often opted to prod workers by instilling fear of layoffs. Gordon unerringly plots the shortsighted and disastrous course of U.S. corporations, and documents the tremendous social and personal costs to their employees. Yet in addition to telling the harsh truth about downsizing, he suggests policies to ensure fairer business practices. Wages can increase— indeed, they must—as the economy begins to perform more efficiency. U.S. corporations have become fat and mean. They need to become lean and decent—not just for the sake of their workers, but for the sake of their competitive advantage. This provocative and original book shows how they can.
Oriented toward the introductory student, The Inequality Reader is the essential textbook for today's undergraduate courses. The editors, David B. Grusky and Szonja Szelenyi, have assembled the most important classic and contemporary readings about how poverty and inequality are generated and how they might be reduced. With thirty new readings, the second edition provides new materials on anti-poverty policies as well as new qualitative readings that make the scholarship more alive, more accessible, and more relevant. Now more than ever, The Inequality Reader is the one-stop compendium of all the must-read pieces, simply the best available introduction to the stratifi cation canon.
In An All-Surpassing Fellowship, David P. Beaty introduces us to the spiritual life of Robert Murray M‘Cheyne. After giving an overview of the life of this remarkable Scottish pastor, Beaty analyzes M‘Cheyne’s study of the Bible, prayer life, pursuit of holiness, eternal perspective, and dependence on the Holy Spirit to see the rich contribution they made to his communion with God. Yet Beaty conducts these investigations with a view toward application—learning from M‘Cheyne that which will help us walk more closely with Christ. See why M‘Cheyne’s communion with God has encouraged many believers over the years, and be encourage yourself to seek that same sweet fellowship with the Lord. Table of Contents: Part 1: Robert Murray M‘Cheyne 1. M’Cheyne’s Early Life and Preparation for Ministry 2. Pastoral Ministry 3. Preaching, Theology, and Pastoral Letters 4. The Mission of Discovery 5. Revival and M‘Cheyne’s Final Days Part 2: M‘Cheyne’s Communion with God 6. Communion with God by His Word 7. Communion with God in Prayer 8. The Joy of Holiness 9. Eternal Perspective 10. Communion with the Holy Spirit Part 3: Learning from M‘Cheyne 11. Really understanding the Gospel 12. Pleasure and Power in Prayer 13. The Purposeful Pursuit of Holiness 14. Passion and Power for Evangelism 15. Preparation for Revival
Covering the full spectrum of rehabilitation after traumatic brain injury, this practical reference by Drs. Blessen C. Eapen and David X. Cifu presents best practices and considerations for numerous patient populations and their unique needs. In an easy-to-read, concise format, it covers the key information you need to guide your treatment plans and help patients relearn critical life skills and regain their independence. - Covers neuroimaging, neurosurgical and critical care management, management of associated complications after TBI, pharmacotherapy, pain management, sports concussion, assistive technologies, and preparing patients for community reintegration. - Discusses special populations, including pediatric, geriatric, and military and veteran patients. - Consolidates today's available information and guidance in this challenging and diverse area into one convenient resource.
Nachituti’s Gift challenges conventional theories of economic development with a compelling comparative case study of inland fisheries in Zambia and Congo from pre- to postcolonial times. Neoclassical development models conjure a simple, abstract progression from wealth held in people to money or commodities; instead, Gordon argues, primary social networks and oral charters like “Nachituti’s Gift” remained decisive long after the rise of intensive trade and market activities. Interweaving oral traditions, songs, and interviews as well as extensive archival research, Gordon’s lively tale is at once a subtle analysis of economic and social transformations, an insightful exercise in environmental history, and a revealing study of comparative politics. Honorable Mention, Melville J. Herskovits Award, African Studies Association “A powerful portrayal of the complexity, fluidity, and subtlety of Lake Mweru fishers’ production strategies . . . . Natchituti’s Gift adds nuance and evidence to some of the most important and sophisticated conversations going on in African studies today.”—Kirk Arden Hoppe, International Journal of African Historical Studies “A lively and intelligent book, which offers a solid contribution to ongoing debates about the interplay of the politics of environment, history and economy.”—Joost Fontein, Africa “Well researched and referenced . . . . [Natchituti’s Gift] will be of interest to those in a wide variety of disciplines including anthropology, African Studies, history, geography, and environmental studies.”—Heidi G. Frontani, H-SAfrica
Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequences. Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures, a combination of factors that we choose and do not choose. Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics. In the decade since the first edition published, knowledge of genetic influences on the neurogenetic underpinnings of behavior has been transformed by genomic technologies. Genome-Wide Association studies, for example, have revealed that hundreds of genes influence vulnerability to psychiatric disease and innate predisposition to risk-taking behaviors. This new edition has been thoroughly revised to focus on free will and its neurogenetic origins. In addition, the use of polygenic scores for behavioral prediction are discussed in-depth, reflecting the GWAS (Genome-Wide Association Study) revolution and combined use of genetic predictors in polygenic scores. Sections on epigenetics are also substantially expanded throughout, better defined, and tied to neuroplasticity and gene-environment interaction. Figures and illustrations have been added or improved throughout, and disease nosology and terminology has been updated. - Updates on the previous edition which was the First Prize winner of the 2013 BMA Medical Book Award for Basic and Clinical Sciences - Poses and resolves challenges to moral responsibility raised by modern genetics and neuroscience - Analyzes the neurogenetic origins of human behavior and free will - Features expanded sections on the neurogenetic basis of free will, polygenic risk scores, and epigenetic influence over behavior, as well as improved figures and updated terminology
This title is the second volume in a four volume series on the cemeteries of Jackson and Sandy Ridge Townships in Union County, North Carolina. It contains information on 144 cemeteries and 27,524 graves.
An Adjunct Provider's Guide to Driving With Care: Education and Treatment of the Impaired Driving Offender--Strategies for Responsible Living and Change
An Adjunct Provider's Guide to Driving With Care: Education and Treatment of the Impaired Driving Offender--Strategies for Responsible Living and Change
This supplementary guide to the Driving with Care series examines the reasons behind adolecent and young adult drink driving offences and how they differ from the adult offender.
Youth have nearly always exhibited behaviors that frustrate adults. It can be diffi cult to understand why young people engage in risky or destructive behavior, and it is challenging to develop strategies to encourage more healthy and responsible behavior among our youth. However, it is helpful to realize that despite the fact that large numbers of youth engage in frightful and destructive behaviors for pe riods of time during adolescence and early adulthood, a large proportion of youth find a way not only to survive but also to bounce back and contribute significantly to the furtherance of human development. We are not the first generation of adults to experience the pain, fear, and frustration of dealing with our youth. More important, we recognize that we are not helpless when faced with the problems youth experience. While it is true that adolescents have always exhibited problem behaviors, a number of effective tools and approaches have always been at our disposal to assist with appropriate youth development. Of course, the most effective approaches require a tremendous amount of focused time and energy.
Written by recognized experts in their respective fields, the books of the Series in Specialty Competencies in Professional Psychology are comprehensive, up-to-date, and accessible. These volumes offer invaluable guidance to not only practicing mental health professionals, but those training for specialty practice as well.
Valence bond (VB) theory, which builds the descriptions of molecules from those of its constituent parts, provided the first successful quantum mechanical treatments of chemical bonding. Its language and concepts permeate much of chemistry, at all levels. Various modern formulations of VB theory represent serious tools for quantum chemical studies of molecular electronic structure and reactivity. In physics, there is much VB-based work (particularly in semi-empirical form) on larger systems. Importance of TopicThe last decade has seen significant advances in methodology and a vast increase in the range of applications, with many new researchers entering the field.Why This TitleValence Bond Theory succeeds in presenting a comprehensive selection of contributions from leading valence bond (VB) theory researchers throughout the world. It focuses on the vast increase in the range of applications of methodology based on VB theory during the last decade and especially emphasizes recent advances.
Volume Four of this series contains the alphabetical rosters of each of the 144 cemeteries in the study area of Jackson and Sandy Ridge Townships, Union Co., NC. It includes over 27,524 graves.
The creation of plant-based foods is one of the most rapidly advancing areas in the modern food industry. Many consumers are adopting more plant-based foods in their diets because of concerns about global warming and its devastating impacts on the environment and biodiversity. In addition, consumers are adopting plant-based diets for ethical and health reasons. As a result, many food companies are developing plant-based analogs of animal-based foods like dairy, egg, meat, and seafood products. This is extremely challenging because of the complex structure and composition of these animal-based foods. Next-Generation Plant-based Foods: Design, Production and Properties presents the science and technology behind the design, production, and utilization of plant-based foods. Readers will find a review of ingredients, processing operations, nutrition, quality attributes, and specific plant-based food categories such as milk and dairy products, egg and egg products, meat and seafood products, providing the fundamental knowledge required to create the next generation of healthier and more sustainable plant-based food alternatives.
New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future.* Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields
The BBC's Jazz Book of the Year for 2008. Few jazz musicians have had the lasting influence or attracted as much scholarly study as John Coltrane. Yet, despite dozens of books, hundreds of articles, and his own recorded legacy, the "facts" about Coltrane's life and work have never been definitely established. Well-known Coltrane biographer and jazz educator Lewis Porter has assembled an international team of scholars to write The John Coltrane Reference, an indispensable guide to the life and music of John Coltrane. The John Coltrane Reference features a a day-by-day chronology, which extends from 1926-1967, detailing Coltrane's early years and every live performance given by Coltrane as either a sideman or leader, and a discography offering full session information from the first year of recordings, 1946, to the last, 1967. The appendices list every film and television appearance, as well as every recorded interview. Richly illustrated with over 250 album covers and photos from the collection of Yasuhiro Fujioka, The John Coltrane Reference will find a place in every major library supporting a jazz studies program, as well as John Coltrane enthusiasts.
Accommodating the diversity of learners in mainstream schooling and providing high quality education for all, inclusive education is prioritised at international and European levels as a human rights issue and as a reform strategy which tackles inequalities and promotes social cohesion within both schools and wider society. This book advances critical realist ideas in empirical research in order to close the theory–practice gap and shift the emphasis from epistemology to ontology with regard to teachers’ empowerment to provide inclusive education. With a focus on the school context rather than the agency of the individual teacher, the authors use empirical data from case studies to demonstrate teachers’ disempowerment as real, and rooted in features of reality. Offering a unified critical realist model, the book challenges taken-for-granted ideas and practices concerning the empowerment of teachers in inclusive education and seeks to set the ground for a more holistic and inclusive educational change.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.