Carefully coordinated, reliable, and accurate time synchronization is vital to a wide spectrum of fields—from air and ground traffic control, to buying and selling goods and services, to TV network programming. Ill-gotten time could even lead to the unimaginable and cause DNS caches to expire, leaving the entire Internet to implode on the root servers. Written by the original developer of the Network Time Protocol (NTP), Computer Network Time Synchronization: The Network Time Protocol on Earth and in Space, Second Edition addresses the technological infrastructure of time dissemination, distribution, and synchronization—specifically the architecture, protocols, and algorithms of the NTP. This system has been active in one form or another for almost three decades on the Internet and numerous private networks on the nether side of firewalls. Just about everything today that can be connected to a network wire has support for NTP. This book: Describes the principal components of an NTP client and how it works with redundant servers and diverse network paths Provides an in-depth description of cryptographic and other critical algorithms Presents an overview of the engineering principles guiding network configuration Evaluating historic events that have taken place since computer network timekeeping started almost three decades ago, the author details a number of systems and drivers for current radio, satellites, and telephone modem dissemination and explains how we reckon the time, according to the stars and atoms. The original 16 chapters of the first edition have been rewritten, updated, and enhanced with new material. Four new chapters cover new algorithms and previously uncovered concepts, including timekeeping in space missions. Praise for the first edition: "... For those that need an exhaustive tome on all of the minutiae related to NTP and synchronization, this is the source. ... definitive ... this book should be considered the last word on the topic." —Ben Rothke on Slashdot.org "... the bible of the subject... contains enough information to take you just as far as you want to go....Dr. Mills is the original developer of NTP." —Books On-Line
A study of the political reaction against the 18th Amendment, a response that led to its reversal 14 years later by the 21st Amendment. This work uses archival evidence to examine the liquor ban and to draw attention to the bi-partisan movement led by the Association Against Prohibition Amendment.
From the jungles of Vietnam, where he shot a photo of "the loneliness and desolation of war" that won a Pulitzer Prize, to the impeachment trial of President Bill Clinton, David Hume Kennerly witnessed and photographed most of the history-making moments of the last third of the twentieth century. As the millennium turned and he set out to cover his eighth presidential campaign, however, the veteran photojournalist sensed something missing. In his words, "I had the uneasy feeling that I couldn't focus only on the story at hand while bypassing the texture of life that surrounds it.... This time I wouldn't speed across that covered bridge to get to the big event on the other side, but instead I would slow down a bit, maybe even pause to take a picture of the bridge." Photo du Jour is Kennerly's visual diary of "the texture of life" at the start of the twenty-first century. As he traveled more than a quarter of a million miles across thirty-eight states and seven countries, Kennerly took a picture every single day in the year 2000, using just one camera and one lens. Some offer candid, behind-the-scenes glimpses of the men who would be president--John McCain, Al Gore, and George W. Bush. Most of the photographs, though, seek to capture not the big, historic moments but rather the ordinary, even whimsical moments when the essence of a person or a place reveals itself to the observer who takes the time and has the heart to really see. Travel with him from Beijing to Boston, Moose to Miami, and Whynot to Weimea in Photo du Jour, and you'll quickly discover that David Kennerly is just such an observer.
The experiences of the families rang true throughout. I have experienced many of these personally. ...It made me think differently about my personal experience as a parent of a child with cancer and my son's current social experiences." Macmillan Cancer Support This book offers a radical critique of existing psychosocial research on children’s experiences of cancer and proposes an alternative view informed by recent interpretive perspectives. Exploring topics from obtaining a diagnosis of childhood cancer through to sharing decision-making and communication, it reviews a wide-ranging body of research and theory on childhood, chronic illness, and cancer. The book also examines research that has focused on how parents and other family members experience childhood illness. Written by a sociologist, a psychologist and a practising paediatric oncologist, this book is unique in its approach and provides key reading across traditional disciplinary boundaries. In particular, the book highlights the emerging contribution of interpretive work to understanding chronic childhood illness and further develops the dialogue that has only recently emerged between the sociology of illness and the sociology of childhood. Rethinking Experiences of Childhood Cancer is aimed at researchers, students and practitioners in the fields of social science, childhood studies, nursing, medicine, mental health care, social work, clinical psychology and other professions allied to medicine, and will also be of interest to families who have been affected by childhood cancer.
Portraits in Steel is the authors' effort to help explain and to save something of the heritage of a once-vital company and to portray its wide-ranging impact on the local and national community."--BOOK JACKET.
Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain. Who should buy this book? Pharmacology of Pain is a particularly useful resource for: Basic researchers and clinicians, including physicians, dentists, pharmacists, nurses, and physical therapists Other professionals in the field of pain research and treatment Students and trainees
Cases in Business Ethics provides the opportunity for students not only to discuss the application of ethical theories in managerial situations, but also to apply judgment and make decisions in a real-world context. This collection of cases focuses on business decision-making, and includes both short and long, more complex cases that highlight the practicalities of business practice and ethical theory. A beneficial feature of Cases in Business Ethics is the variety of ways in which the cases can be organized to fit the course curriculum.
Dead zones are on the rise... Human activity has caused an increase in uninhabitable, oxygen-poor zones--also known as "dead zones"--in our waters. Oxygen is the third most abundant element in the universe, and it is a necessity for nearly all life on Earth. Yet many rivers, estuaries, coastal waters, and parts of the open ocean lack enough of it. In this book, David L. Kirchman explains the impacts of dead zones and provides an in-depth history of oxygen loss in water. He details the role the agricultural industry plays in water pollution, showcasing how fertilizers contaminate water supplies and kickstart harmful algal blooms in local lakes, reservoirs, and coastal oceans. Algae decomposition requires so much oxygen that levels drop low enough to kill fish, destroy bottom-dwelling biota, reduce biological diversity, and rearrange food webs. We can't undo the damage completely, but we can work together to reduce the size and intensity of dead zones in places like the Gulf of Mexico, Chesapeake Bay, and the Baltic Sea. Not only does Kirchman clearly outline what dead zones mean for humanity, he also supplies ways we can reduce their deadly impact on human and aquatic life. Nutrient pollution in some regions has already begun to decline because of wastewater treatment, buffer zones, cover crops, and precision agriculture. More needs to be done, though, to reduce the harmful impact of existing dead zones and to stop the thousands of new ones from cropping up in our waters. Kirchman provides insight into the ways changing our diet can reduce nutrient pollution while also lowering greenhouse gasses emitted by the agricultural industry. Individuals can do something positive for their health and the world around them. The resulting book allows readers interested in the environment--whether students, policymakers, ecosystem managers, or science buffs--to dive into these deadly zones and discover how they can help mitigate the harmful effects of oxygen-poor waters today.
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you’ll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski’s Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need.
Volume Four of this series contains the alphabetical rosters of each of the 144 cemeteries in the study area of Jackson and Sandy Ridge Townships, Union Co., NC. It includes over 27,524 graves.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you'll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski's Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. And, as an Expert Consult title, this thoroughly updated 7th edition comes with access to the complete contents online, fully searchable. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need. Provides access to the complete contents online, fully searchable, enabling you to consult it rapidly from any computer with an Internet connection. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Prove It With Figures displays some of the tools of the social and statistical sciences that have been applied in the courtroom and to the study of questions of legal importance. It explains how researchers can extract the most valuable and reliable data that can conveniently be made available, and how these efforts sometimes go awry. In the tradition of Zeisel's standard work "Say It with Figures," the authors clarify, in non-technical language, some of the basic problems common to all efforts to discern cause-and-effect relationships. Designed as a textbook for law students who seek an appreciation of the power and limits of empirical methods, this is also a useful reference for lawyers, policymakers, and members of the public who would like to improve their critical understanding of the statistics presented to them. The many case histories include analyses of the death penalty, jury selection, employment discrimination, mass torts, and DNA profiling.
From heat waves and wildfires to flooding and record droughts, the impacts of climate change are now obvious. While the primary cause is the rise in greenhouse gases mainly from the burning of fossil fuels such as coal and petroleum, the complete story behind greenhouse gases also involves microbes and what they are doing in natural ecosystems. Although microbes contribute to the problem by producing greenhouse gases, climate change would be even more severe if not for other microbes that consume greenhouse gases. Understanding and solving the biggest environmental problem facing us today depends on the smallest organisms, microbes.
Comprehensive, user-friendly, and up to date, Chestnut's Obstetric Anesthesia: Principles and Practice, 6th Edition, provides the authoritative clinical information you need to provide optimal care to your patients. This substantially revised edition keeps you current on everything from basic science to anesthesia techniques to complications, including coverage of new research that is paving the way for improved patient outcomes. An expert editorial team ensures that this edition remains a must-have resource for obstetric anesthesiologists and obstetricians, nurse anesthetists and anesthesiology assistants, and anesthesiology and obstetric residents and students. - Presents the latest information on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy, emphasizing the treatment of the fetus and the mother as separate patients with distinct needs. - Contains new chapters on shared decision-making in obstetric anesthesia and chronic pain during and after pregnancy. - Features extensive revisions from cover to cover, including consolidated information on maternal infection and postoperative analgesia. - Covers key topics such as neonatal assessment and resuscitation, pharmacology during pregnancy and lactation, use of nitrous oxide for labor analgesia, programmed intermittent epidural bolus (PIEB) technique, epidural analgesia-associated fever, the role of gastric ultrasonography to assess the risk of aspiration, sugammadex in obstetric anesthesia, the role of video laryngoscopy and new supraglottic airway devices, spinal dysraphism, and cardiac arrest in obstetric patients. - Incorporates the latest guidelines on congenital heart disease and the management of sepsis, as well as difficult airway guidelines that are specific to obstetric anesthesia practice. - Offers abundant figures, tables, and boxes that illustrate the step-by-step management of a full range of clinical scenarios. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health." Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
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