This volume offers a comprehensive history of the Mount Desert Island Biological Laboratory (MDIBL), one of the major marine laboratories in the United States and a leader in using marine organisms to study fundamental physiological concepts. Beginning with its founding as the Harpswell Laboratory of Tufts University in 1898, David H. Evans follows its evolution from a teaching facility to a research center for distinguished renal and epithelial physiologists. He also describes how it became the site of major advances in cytokinesis, regeneration, cardiac and vascular physiology, hepatic physiology, endocrinology and toxicology, as well as studies of the comparative physiology of marine organisms. Fundamental physiological concepts in the context of the discoveries made at the MDIBL are explained and the social and administrative history of this renowned facility is described.
Master's Thesis from the year 2012 in the subject Law - Comparative Legal Systems, Comparative Law, grade: Super Distinction, School of Oriental and African Studies, University of London, language: English, abstract: This thesis studies Judicial Yuan Interpretation No.328 [1993] – the first constitutional court decision specifically relating to the use of the political question doctrine in Taiwan. Taiwan’s constitutional court, on the whole, does not refuse to involve itself in political questions, but this case represented an opportunity for the Justices of the Republic of China (Taiwan) to introduce the political question doctrine into Taiwan’s legal system. The Judicial Yuan’s previous and subsequent judicial reviews included cases in which the constitutional court dismissed the authoritarian congress for democratisation or struck down an unconstitutional constitutional amendment. It is therefore doubtful that the Justices would claim to be unable to determine the political question in Judicial Yuan Interpretation No.328 [1993]. The court had by then become too powerful to persuade people that it should address the political question doctrine. The Justices applied the political question doctrine in this case only because they wished to avoid becoming mired in political controversy.
Focusing on high-yield information, Musculoskeletal Imaging: The Core Requisites, 5th edition emphasizes the basics to help you establish a foundational understanding of musculoskeletal imaging during rotations, prepare for the core and certifying exams, refresh your knowledge of key concepts, and learn strategies to provide "value added reports to referring clinicians. This completely rewritten and reorganized edition emphasizes the essential knowledge you need in an easy-to-read format. - Emphasizes the essentials in a templated, quick-reference format that includes numerous outlines, tables, pearls, boxed material, and bulleted content for easy reading, reference, and recall. - Prioritizes and explains the key information that you will be tested on to help you efficiently and effectively prepare for board exams. - Helps you build and solidify core knowledge to prepare you for clinical practice with critical, up-to-date information on sports injuries and other trauma, joint diseases, musculoskeletal tumors and infection, bone marrow imaging, pediatric conditions, and basic image-guided musculoskeletal procedures. - Includes sample report templates and numerous tips on effective communication of imaging findings. - Features more than 1,200 high-quality images spanning the diagnosis of conditions and diseases of the musculoskeletal system. All imaging modalities are covered, including MRI, ultrasound, CT, radiography, and nuclear medicine. - Published as part of the newly reimagined Core Requisites series, an update to the popular Requisites series aimed at radiology trainees and today's busy clinicians. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Graphene supercapacitors, also called ultracapacitors or electrical double-layer capacitors, have increasingly begun to rival conventional batteries. They allow to manipulate the nanoscale structure of carbon-based supercapacitors and offer the additional advantage of sequestering increasing amounts of carbon from the environment, thus helping to limit global warming. The book focuses on the choice of electrode materials, their properties and methods of fabrication. It references 494 original resources with their direct web links for in-depth reading. Keywords: Graphene Supercapacitors, Micro-Supercapacitors, Oxides, Sulfides, Selenides, Hydroxides, Phosphates, Nitrides, Fabrication, Printing, Environmental Effects.
Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.
Classicists, historians of medicine, and working scientists collaborate to guide pharmaceutical researchers to the potential for rediscovering useful drugs from old texts. They discuss the medicines of Greco-Roman antiquity, a case study of the 1570 This Booke of Sovereigne Medicines, identifying plants in pre-Linnaean botanical literature, transforming plant lore into pharmacy, and determining whether a treatment works. Annotation copyrighted by Book News, Inc., Portland, OR
Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic scien
This book reviews the geochemical and petrological characteristics of potassic igneous rock complexes, and investigates the various tectonic settings in which these rocks occur. The authors provide an overview and classification of these rocks and elucidate the geochemical differences between barren and mineralized potassic igneous complexes. High-K rocks are genetically associated with a number of epithermal gold and porphyry copper-gold deposits. In recent years, there has also been growing recognition of an association of such rocks with iron-oxide copper-gold (IOCG) deposits, intrusion-related gold deposits (IRGDs) and Carlin-type gold deposits. This fifth updated and expanded edition incorporates new data and references from world-class copper and gold deposits worldwide. It also includes the latest publications on the petrogenesis of high-K magmatism and related mineral deposits. Numerous new representative ore photographs of the mineral deposits described are also included in the new edition. As such, the book offers a valuable guide not only for academic petrologists working on alkaline rocks, but also for exploration geologists prospecting for epithermal gold and/or porphyry copper-gold deposits in modern and ancient terrains.
Headache syndromes rank amongst the most common presenting symptoms in general practice and neurology, affecting up to 15% of the adult population. Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Headache Syndromes provides clinicians with a definitive resource for diagnosing and managing patients with primary and secondary forms of headaches, either as isolated complaints or as part of a more complex syndrome. Split into 7 key sections with 59 chapters, this comprehensive work discusses the scientific basis and practical management of headache syndromes in a logical format. Each chapter is written by international experts in neurology who share their research and extensive experience by providing a wealth of practical advice for use in clinical situations. In addition, all content is up-to-date and chapters incorporate discussions on the latest International Classification of Headache Disorders 3rd edition when relevant.
Werner & Ingbar’s The Thyroid: A Fundamental and Clinical Text, 10th Edition has been extensively revised and streamlined to deliver the most comprehensive coverage of the thyroid including anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. Entirely new chapters on the surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs are in this edition. New authors and an international group of contributors elevate this classic text that includes extensive clinical coverage of thyroid dysfunction’s effects on other organ systems. Also addressed are clinical controversies regarding the ageing thyroid, subclinical hypothyroidism and hyperthyroidism and thyroid disease in pregnancy. New to this edition: · Twenty-three chapters authored by new contributors and international experts · A companion website with fully searchable text for quick reference · Three new chapters discuss surgical management of thyroid cancer, thyroid disruptors, and thyroid hormone analogs to keep you up-to-date on the latest advances in the field
This series provides an unequalled source of information on an area of chemistry that continues to grow in importance. Divided into sections mainly according to the particular spectroscopic technique used, coverage in each volume includes: NMR (with reference to stereochemistry, dynamic systems, paramagnetic complexes, solid state NMR and Groups 13-18); nuclear quadrupole resonance spectroscopy; vibrational spectroscopy of main group and transition element compounds and coordinated ligands; and electron diffraction. Reflecting the growing volume of published work in the field, researchers will find this an invaluable source of information on current methods and applications. Volume 39 provides a critical review of the literature published up to late 2004.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Pediatric Surgery** Now in brilliant full color and reflecting recent significant changes in the field, Critical Heart Disease in Infants and Children, 3rd Edition, keeps you abreast of the skills and knowledge required to safely care for children with congenital and acquired heart disease in the ICU. Pediatric intensivists, cardiologists, cardiac surgeons, and anesthesiologists from leading centers around the world provide a well-rounded perspective on basic scientific principles, medical and pharmacologic treatments, surgical techniques, and equipment. - Features comprehensive updates throughout the text, including indications, techniques, potential complications in perioperative management of patients, and surgical techniques for congenital heart disease. - Covers recent advances in the treatment of pulmonary hypertension, developments in mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization. - Features an all-new, full-color format that speeds navigation and helps clarify complex concepts. - Contains 27 new chapters with an emphasis on the team approach to patient care in the ICU including creating multidisciplinary teams, quality and performance improvement, training , and challenges and solutions to developing a cohesive team environment. - Includes a detailed chapter on bedside ultrasound, walking you through the techniques you're most likely to encounter in the ICU. - Employs well-documented tables, text boxes, and algorithms to make clinical information easy to access, and more than two dozen video clips provide a more complete understanding of echocardiography, imaging modalities, pulmonary hypertension, and more. - Describes the basic pharmacology and clinical applications of new pharmacologic agents. - Examines issues affecting adults with congenital heart disease. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. - Offers four completely new chapters: Cardiac Trauma, Congenital Heart Disease in the Adult, Congenitally Corrected Transposition of the Great Arteries, and Outcome Evaluation. - Describes the basic pharmacology and clinical applications of all of the new pharmacologic agents. - Details important refinements and developments in surgical techniques, including the Ross pulmonary autograft replacement of the aortic valve, video-assisted fluoroscopy, and the extracardiac Fontan connection, and discusses their indications and potential complications. - Explores the latest advances in the treatment of pulmonary hypertension, new developments in mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization. - Examines issues affecting adults with congenital heart disease.
Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as a practical resource with "problems and pitfalls" highlighted throughout to aid laboratory diagnosis.
This handbook covers a number of the more recent developments regarding the mechanics of deforming solids. In recent years, much progress has been reported in the wide-ranging mechanical behaviour of solids under stress. Here the term stress in a solid arises from a number of external actions including direct tension, compression, pressure, bending, shear and torsion. Many of the topics covered are yet to find their way into the standard texts, which are often restricted to isotropic elasticity and plasticity.In this two-volume work, what might previously have been regarded as disparate, 'specialist' topics have been placed within a wider mechanics arena to emphasise their common, underlying principles. That arena is taken generally as one of inelasticity for dealing with the essential mechanics of these phenomena. Therein, this text brings together theory, experimental data, key references, examples and exercises, particularly those that relate to the important advances in the subject, both old and new. The presentation of material featured in this way anticipates that in their turn these additional topics will be recognised as essential material for study among engineers, physicists and applied mathematicians at undergraduate and postgraduate levels.
This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.
For the past decade, Chinese military strategists have keenly observed the changes in U.S. national strategy and military transformation. This report examines the constraints, facilitators, and potential options for Chinese responses to U.S. transformation efforts and offers possible U.S. counterresponses (particularly in light of whether Taiwan moves toward or away from formal independence).
Used by generations of physicians who encounter patients with dermatological diseases, Lever’s Dermatopathology: Histopathology of the Skin comprehensively covers skin disease in which histopathology plays an important role in diagnosis. The updated 12th Edition, edited by Drs. David E. Elder, Rosalie Elenitsas, George F. Murphy, Misha Rosenbach, Adam I. Rubin, John T. Seykora, and Xiaowei Xu, maintains the proven, clinicopathologic classification of cutaneous disease while incorporating a “primer” on pattern-algorithm diagnosis. It features larger images throughout, as well as thoroughly revised content with new diseases and new information on pathophysiology and molecular pathogenesis—all in an easy-to-navigate, highly readable format.
Provides a description of the thermodynamic model, data treatment procedures and the thermodynamic constants for hydrous ferric oxide. Includes detailed coverage of the model and the parameter extraction procedure.
The study of biofilm considers the close association of micro-organisms with each other at interfaces and is relevant to a variety of disciplines, including medicine, dentistry, bioremediation, biofouling, water technology, engineering and food science. Although the habitats studied differ widely, some common elements exist such as method of attachment, coadhesion and regulation of biofilm phenotype and architecture. This book aims to distil the common principles of biofilm physiology and growth for all interested disciplines.
Authored by a team of experts, the new edition of this bestseller presents practical techniques for managing inventory and production throughout supply chains. It covers the current context of inventory and production management, replenishment systems for managing individual inventories within a firm, managing inventory in multiple locations and firms, and production management. The book presents sophisticated concepts and solutions with an eye towards today’s economy of global demand, cost-saving, and rapid cycles. It explains how to decrease working capital and how to deal with coordinating chains across boundaries.
This book describes the experimental and theoretical bases for the development of specifically quantum-mechanical approaches to metrology, imaging, and communication. In particular, it presents novel techniques developed over the last two decades and explicates them both theoretically and by reference to experiments which demonstrate their principles in practice. The particular techniques explored include two-photon interferometry, two-photon optical aberration and dispersion cancellation, lithography, microscopy, and cryptography.
Presenting information typically not found in other books, the authors explore the numerous advantages of these antennas - including high-speed signal acquisition, fixed input impedance, low loss, and small footprint. Professionals find practical design examples, strategies, and optimization methods for designing economical switched parasitic antennas for applications such as direction finding and multibeam communications systems. Cutting-edge technologies and applications such as MEMs RF switches are also discussed."--Jacket.
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A "who’s who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers.
Written by one of the most distinguished experts on China's economic and business history, China and Capitalism provides a highly original and at the same time clear and readable approach to understanding the development of business in China from 1500 to the 1990s. David Faure then uses the picture he has assembled to shed new light on the strengths and weaknesses of Chinese business today. The book is written to be accessible to people with little background in China or Chinese business practice. Dr Faure describes three phases in the development of Chinese business from the sixteenth to the twentieth century. In the traditional phase, from the sixteenth to the eighteenth century, Chinese business relied on contracts as well as on ritual propriety. In the modernizing phase, from the second half of the nineteenth century to the first half of the twentieth century, Chinese business had to adapt to the introduction of company law and legal standards of accounting. In the contemporary phase, from the middle of the twentieth century to the present day, China emerged from a control economy to a vibrant market by embracing once again the changes introduced in the modernizing phase. General readers, including students and teachers in courses touching on but not primarily devoted to the Chinese experience, will find in this book the most comprehensive account of China's business development in the last five centuries and many insights into the workings of China's modern business scene. Specialist readers will find a highly original approach to the history of business in China.
Key imperial and royal courts--in Han, Tang, and Song dynasty China; medieval and renaissance Europe; and Heian and Muromachi Japan--are examined in this comparative and interdisciplinary volume as loci of power and as entities that establish, influence, or counter the norms of a larger society. Contributions by twelve scholars are organized into sections on the rhetoric of persuasion, taste, communication, gender, and natural nobility. Writing from the perspectives of literature, history, and philosophy, the authors examine the use and purpose of rhetoric in their respective areas. In Rhetoric of Persuasion, we see that in both the third-century court of the last Han emperor and the fourteenth-century court of Edward II, rhetoric served to justify the deposition of a ruler and the establishment of a new regime. Rhetoric of Taste examines the court’s influence on aesthetic values in China and Japan, specifically literary tastes in ninth-century China, the melding of literary and historical texts into a sort of national history in fifteenth-century Japan, and the embrace of literati painting innovations in twelfth-century China during a time when the literati themselves were out of favor. Rhetoric of Communication considers official communications to the throne in third-century China, the importance of secret communications in Charlemagne’s court, and the implications of the use of classical Chinese in the Japanese court during the eighth and ninth centuries. Rhetoric of Gender offers the biography of a former Han emperor’s favorite consort and studies the metaphorical possibilities of Tang palace plaints. Rhetoric of Natural Nobility focuses on Dante’s efforts to confirm his nobility of soul as a poet, surmounting his non-noble ancestry, and the development of the texts that supported the political ideologies of the fifteenth-century Burgundian dukes Philip the Good and Charles the Bold.
Neuroinflammation has long been studied for its connection to the development and progression of Multiple Sclerosis. In recent years, the field has expanded to look at the role of inflammatory processes in a wide range of neurological conditions and cognitive disorders including stroke, amyotrophic lateral sclerosis, and autism. Researchers have also started to note the beneficial impacts of neuroinflammation in certain diseases. Neuroinflammation: New Insights into Beneficial and Detrimental Functions provides a comprehensive view of both the detriments and benefits of neuroinflammation in human health. Neuroinflammation: New Insights into Beneficial and Detrimental Functions opens with two chapters that look at some fundamental aspects of neuroinflammation in humans and rodents. The remainder of the book is divided into two sections which examine both the detrimental and beneficial aspects of inflammation on the brain, spinal cord and peripheral nerves, on various disease states, and in normal aging. These sections provide a broad picture of the role neuroinflammation plays in the physiology and pathology of various neurological disorders. Providing cross-disciplinary coverage, Neuroinflammation: New Insights into Beneficial and Detrimental Functions will be an essential volume for neuroimmunologists, neurobiologists, neurologists, and others interested in the field.
This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
This comprehensive book describes the fundamental properties of soft X-rays and extreme ultraviolet (EUV) radiation and discusses their applications in a wide variety of fields, including EUV lithography for semiconductor chip manufacture and soft X-ray biomicroscopy. The author provides a wealth of useful reference material such as electron binding energies, characteristic emission lines and photo-absorption cross-sections. The book will be of great interest to graduate students and researchers in engineering, physics, chemistry, and the ...
Blockchain is transforming business. What's your strategy? Leaders of forward-thinking organizations are exploring how blockchain can transform the way they create and seek value. Whether it's used to streamline multiparty processes, create and trade new assets, or leverage artificial intelligence and the internet of things, blockchain enables entirely new business opportunities. This is just the start. As blockchain becomes more widely adopted, it has the potential to radically change the way companies and societies operate, as transformative a paradigm shift as the launch of the internet. The Real Business of Blockchain is one of the first books on this transformative technology written for business leaders. Authors David Furlonger and Christophe Uzureau--both of Gartner, the world-renowned research and advisory company--will help you: Assess how blockchain will impact your business Explore the value proposition that blockchain offers Make smart near- and midterm investments Position your organization in a new competitive landscape Timely, visionary, and accessible, The Real Business of Blockchain cuts through the hype and helps you unlock the vast capabilities of this powerful and potentially world-changing technology.
This book provides, in a single cohesive source, all the information a health care professional needs to diagnose and select appropriate treatments for the patient with pain associated with cancer. Cancer Pain: Assessment, Diagnosis, and Management is clinically oriented and comprehensively addresses all the issues surrounding modern cancer pain management. The authors provide detailed information on common but difficult to treat cancer pain scenarios. Coverage includes state-of-the-art information on treatment options and discussions of the impact of radiation, chemotherapy, and surgery on pain management. This authoritative, comprehensive clinical reference is essential for all clinicians who treat patients with cancer, including medical oncologists, radiation oncologists, surgeons, pain specialists, anesthesiologists, primary care physicians, internists, and nurses.
Greenfield's Neuropathology, the worlds leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis and their clinical manifestations. This account is underpinned throughout by a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. While this scientific content is of paramount importance, however, care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that also places the neuropathological findings within the context of a broader diagnostic process. The new eighth edition incorporates much new information, new illustrations and many new authors, while retaining the depth, breadth and quality of content so praised in previous editions. Each chapter opens with an introductory section designed to offer an integrated approach to diagnosis, taking account of clinical manifestations, neuroradiological and laboratory findings as well as the neuropathological and molecular genetic features of the diseases being considered. Strong emphasis has been placed on facilitating the retrieval of neuropathological information by non-neuropathologists grapping with differential diagnoses or seeking information on broad categories of neurological disease, and boxes and tables are used to present important symptoms and signs, patterns of disease and other features for ease of reference. High quality line and photographic illustrations, the majority in full colour, are all available on a companion CD, to complete the offering.
The text that bridges the gap between basic neuroscience and clinical practice – updated with the latest advances and full-color illustrations For more than twenty years, Clinical Neurology has helped students, residents, and clinicians understand the link between basic neuroscience and current approaches in diagnosis and treatment. Distinguished by its practice-oriented approach to neurology based on presenting symptoms, this trusted classic delivers the clearest and most concise introduction to the field available anywhere. Features: Essential concepts are presented within a framework of problems encountered in a clinical setting for greater relevance to real-world practice More than 200 tables and figures put key information at your fingertips Treatment protocols reflect the most recent advances in the field Advances in molecular biology and genetics are incorporated throughout NEW Introductory chapters on the neurologic history and examination and laboratory investigations NEW State-of-the-art discussions of the molecular basis of Alzheimer disease and other dementias, spinocerebellar ataxias, motor neuron disease, muscular dystrophies, Parkinson disease, Huntington disease, multiple sclerosis, epilepsy and stroke; and coverage of recent advances in the treatment of neurologic complications of general medical disorders, headache and facial pain, movement disorders, seizures, and cerebrovascular disease, and other conditions NEW Full-color illustrations that clarify neuroanatomic principles, clinical-anatomic correlations, pathophysiologic mechanisms, and clinical and radiological signs
Offering comprehensive coverage of this fast-changing field for more than 20 years, Urologic Surgical Pathology is an expert guide to all common and rare entities in the genitourinary system. The 4th Edition keeps you fully up to date with discussions of newly recognized tumors and terminologies, the latest classification schemes, current grading approaches, molecular alterations, and commonly used ancillary diagnostic techniques. With its clinical focus on day-to-day urological pathology sign-out and an emphasis on clinicopathologic and radiographic-pathologic correlations, this thoroughly revised uropathology reference is an excellent resource for diagnostic decision making. - Includes expanded coverage of differential diagnosis for all tumor types encountered in urological surgical pathology practice. - Incorporates the latest TNM staging and WHO classification systems, as well as new diagnostic biomarkers and their utility in differential diagnosis, newly described variants and new histologic entities. - Discusses advances in molecular diagnostic testing, its capabilities, and its limitations, including targeted therapy/personalized medicine. - Covers new developments in immunohistochemistry and the latest diagnostic tumor markers. - Features more than 1,600 high-quality images – all in color – including gross pictures, histopathologic and cytopathologic images, special stains, other ancillaries, drawings, and illustrations. - Helps you find information quickly with a consistent chapter format; an abundance of tables, diagrams and flowcharts; boxed lists of types and causes of diseases; differential diagnosis; characteristic features of diseases; complications; classifications; and staging. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Meant for quick retrieval of vital information regarding the management of nutritional issues in patients with gastroenterological problems--either primary or as the consequence of other medical disorders, such as diabetes, hyperlipidemia and obesity. The book addresses normal physiology and pathophysiology, and offers chapters on diseases that can lead to specific nutritional problems. The clinical focus is on therapeutic nutrition and dietary management.
This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.* Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems* Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory* Provides a balanced treatment of the strengths and weaknesses in modern experimental design
Biometrics-based authentication and identification are emerging as the most reliable method to authenticate and identify individuals. Biometrics requires that the person to be identified be physically present at the point-of-identification and relies on `something which you are or you do' to provide better security, increased efficiency, and improved accuracy. Automated biometrics deals with physiological or behavioral characteristics such as fingerprints, signature, palmprint, iris, hand, voice and face that can be used to authenticate a person's identity or establish an identity from a database. With rapid progress in electronic and Internet commerce, there is also a growing need to authenticate the identity of a person for secure transaction processing. Designing an automated biometrics system to handle large population identification, accuracy and reliability of authentication are challenging tasks. Currently, there are over ten different biometrics systems that are either widely used or under development. Some automated biometrics, such as fingerprint identification and speaker verification, have received considerable attention over the past 25 years, and some issues like face recognition and iris-based authentication have been studied extensively resulting in successful development of biometrics systems in commercial applications. However, very few books are exclusively devoted to such issues of automated biometrics. Automated Biometrics: Technologies and Systems systematically introduces the technologies and systems, and explores how to design the corresponding systems with in-depth discussion. The issues addressed in this book are highly relevant to many fundamental concerns of both researchers and practitioners of automated biometrics in computer and system security.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
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