Not-a-pe-ka-gon was the Native American name given to the Ludington area and translates as "heads on sticks." The name refers to a battle between the Ottawa and Mascouten Indians in the 17th century that raged along the river toward Lake Michigan. The heads of the defeated Mascoutens were placed on sticks as a warning to all. Later a bluff overlooking the lake and river was the site of the 1675 death of Fr. Jacques Marquette, a Jesuit missionary and explorer. When the first settlers of European descent arrived, they gave the name of Pere Marquette to their village, lake, and river in honor of the fallen missionary. Eventually renamed after lumber baron James Ludington, the community became a bustling maritime port and the home of the largest car ferry fleet in the world. David K. Petersen is a local historian and collector of historical images. He has published two pictorial books of the Pere Marquette car ferries based on the photography of Erhardt Peters and currently writes a weekly history column for the Ludington Daily News. Petersen has selected many unique images from his collection to illustrate the maritime history of Ludington from its humble beginnings to an important port of call. The Images of America series celebrates the history of neighborhoods, towns, and cities across the country. Using archival photographs, each title presents the distinctive stories from the past that shape the character of the community today. Arcadia is proud to play a part in the preservation of local heritage, making history available to all.
Oceana County, named for the great freshwater ocean of Lake Michigan, was formed in 1831 and organized on February 13, 1855. The great forest seemed to be an ocean itself, a never-ending sea of green gold for the lumber barons to exploit. The harvest of these mammoth stands of pines brought men and their families to the area to work and build their fortunes. As with many of its immediate neighbors, Oceana County was forged from the exploits of trappers and lumbermen--it was sustained and nurtured by the farmers and businessmen who remained. They built communities on the pine-stumped fields that were left after the great stands of White Pine were shipped out to build the ever-expanding cities of a growing nation. ?
Focusing on cancer in dogs and cats, this extensively updated 4th edition provides comprehensive coverage of the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. Ideal for students, practitioners, and those involved in academic research, this book's full-color images and user-friendly format provide quick and easy access to today's most important information on cancer in the small animal patient. Full-color format throughout and full-color illustrations make information more accessible and provide accurate representations of clinical appearance. Chapters are clustered into four major sections: The Biology and Pathogenesis of Cancer, Diagnostic Procedures for the Cancer Patient, Therapeutic Modalities for the Cancer Patient, and Specific Malignancies in the Small Animal Patient. The consistent format includes incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies in the small animal cancer patient. Features cutting edge information on the complications of cancer, pain management, and the latest treatment modalities. The latest information on the etiology of cancer, including genetic, chemical, physical, and hormonal factors, as well as cancer-causing viruses. Coverage of molecular-targeted therapy of cancer, plus new and emerging therapeutic techniques. New information on molecular diagnostic procedures for the cancer patient. The latest diagnostic imaging techniques in clinical oncology. Discussions of compassion and supportive care, from chronic pain management and nutrition to end-of-life issues and grief support.
This Second Edition of the critically acclaimed, best-selling textbook retains all of the features of the first but with greater coverage and pedagogic focus than before. All chapters from the original edition have been substantially rewritten with the aim of greater clarity and provide updates of the latest research. Five new chapters have been added to reflect the expansion of health psychology and its increasing relevance to the world of health care.
Mason County: 1850-1950 portrays the settlement and growth of Mason County, Michigan, as the area transformed from a land covered in virgin pine and native settlements to communities of farmers and manufacturers. This history of the region begins with images of logging and mills and follows the growth of towns, villages, and individual townships. The adversity, struggles, successes, and joys of carving a new life from the wilderness are captured in more than 200 carefully selected images. These unique photographs illustrate a life of hardship, service, and dedication to faith, family, and community as the area transitioned and changed over the decades.
Focusing on the role that automorphisms and equivalence relations play in the algebraic theory of minimal sets provides an original treatment of some key aspects of abstract topological dynamics. Such an approach is presented in this lucid and self-contained book, leading to simpler proofs of classical results, as well as providing motivation for further study. Minimal flows on compact Hausdorff spaces are studied as icers on the universal minimal flow M. The group of the icer representing a minimal flow is defined as a subgroup of the automorphism group G of M, and icers are constructed explicitly as relative products using subgroups of G. Many classical results are then obtained by examining the structure of the icers on M, including a proof of the Furstenberg structure theorem for distal extensions. This book is designed as both a guide for graduate students, and a source of interesting new ideas for researchers.
MacFadyen shows that the works of John Donne, the existential philosophy of Kierkegaard and Sestov, and the cities of St Petersburg and Venice inspired in Brodsky a fundamentally Baroque evolution. He provides a compelling and comprehensive examination of Brodsky's poetry and prose in a fascinating overview of some problems of post-soviet aesthetics. The book concludes with a reassessment of Brodsky's final role, that of cross-cultural, bilingual essayist. Joseph Brodsky and the Baroque will appeal to students and scholars of Russian literature as well as the growing body of Brodsky's admirers.
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
The Structure of Rare-Earth Metal Surfaces introduces the concepts of surface crystallography and surface-structure determination, outlines the principles of the most widely used experimental techniques and theoretical simulations, and reviews their application to the surfaces of rare-earth metals. In particular, the results of quantitative low-energy electron-diffraction experiments and multiple-scattering calculations axe covered in some depth. The book is aimed at science graduates with an interest in surface crystallography.
From the Department of Epidemiology at Johns Hopkins University and continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, comes the fully revised 6th Edition of Gordis Epidemiology. This bestselling text provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. New coverage includes expanded information on genetic epidemiology, epidemiology and public policy, and ethical and professional issues in epidemiology, providing a strong basis for understanding the role and importance of epidemiology in today's data-driven society. - Covers the basic principles and concepts of epidemiology in a clear, uniquely memorable way, using a wealth of full-color figures, graphs, charts, and cartoons to help you understand and retain key information. - Reflects how epidemiology is practiced today, with a new chapter organization progressing from observation and developing hypotheses to data collection and analyses. - Features new end-of-chapter questions for quick self-assessment, and a glossary of genetic terminology. - Provides more than 200 additional multiple-choice epidemiology self-assessment questions online. - Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
Doubt is our product," a cigarette executive once observed, "since it is the best means of competing with the 'body of fact' that exists in the minds of the general public. It is also the means of establishing a controversy." In this eye-opening expose, David Michaels reveals how the tobacco industry's duplicitous tactics spawned a multimillion dollar industry that is dismantling public health safeguards. Product defense consultants, he argues, have increasingly skewed the scientific literature, manufactured and magnified scientific uncertainty, and influenced policy decisions to the advantage of polluters and the manufacturers of dangerous products. To keep the public confused about the hazards posed by global warming, second-hand smoke, asbestos, lead, plastics, and many other toxic materials, industry executives have hired unscrupulous scientists and lobbyists to dispute scientific evidence about health risks. In doing so, they have not only delayed action on specific hazards, but they have constructed barriers to make it harder for lawmakers, government agencies, and courts to respond to future threats. The Orwellian strategy of dismissing research conducted by the scientific community as "junk science" and elevating science conducted by product defense specialists to "sound science" status also creates confusion about the very nature of scientific inquiry and undermines the public's confidence in science's ability to address public health and environmental concerns Such reckless practices have long existed, but Michaels argues that the Bush administration deepened the dysfunction by virtually handing over regulatory agencies to the very corporate powers whose products and behavior they are charged with overseeing. In Doubt Is Their Product Michaels proves, beyond a doubt, that our regulatory system has been broken. He offers concrete, workable suggestions for how it can be restored by taking the politics out of science and ensuring that concern for public safety, rather than private profits, guides our regulatory policy. Named one of the best Sci-Tech books of 2008 by Library Journal!
In the midst of an addiction epidemic, this newly updated edition of The American Society of Addiction Medicine Principles of Addiction Medicine, 5th edition is the sought-after text every addiction researcher and care provider needs. This comprehensive reference text dedicates itself to both the science and treatment of addiction. You’ll receive a thorough grounding in both the scientific principles behind the causes of addiction and the practical aspects of clinical care. Chapters are written by recognized experts, covering areas such as the basic science of addiction medicine; diagnosis, assessment and early intervention; pharmacologic and behavioral interventions; mutual help and twelve-step; and co-occurring addiction, medical and psychiatric disorders—backed by the latest research data and successful treatment methods. Features: Numerous figures, tables and diagrams elucidate the text Chapters include case examples List of data research reports provided at end of each chapter NEW material on Prescription Drug Abuse, Club Drugs, Nursing Roles in Addressing Addiction, Conceptual and Treatment Issues in Behavioral Addictions, Rehabilitation Approaches to Pain Management, Comorbid Pain and Addiction, Pharmacotherapy for Adolescents with Substance Use Disorders, Preventing and Treating Substance Use Disorders in Military Personnel, and more.
A new edition of the definitive guide to logistic regression modeling for health science and other applications This thoroughly expanded Third Edition provides an easily accessible introduction to the logistic regression (LR) model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables. Applied Logistic Regression, Third Edition emphasizes applications in the health sciences and handpicks topics that best suit the use of modern statistical software. The book provides readers with state-of-the-art techniques for building, interpreting, and assessing the performance of LR models. New and updated features include: A chapter on the analysis of correlated outcome data A wealth of additional material for topics ranging from Bayesian methods to assessing model fit Rich data sets from real-world studies that demonstrate each method under discussion Detailed examples and interpretation of the presented results as well as exercises throughout Applied Logistic Regression, Third Edition is a must-have guide for professionals and researchers who need to model nominal or ordinal scaled outcome variables in public health, medicine, and the social sciences as well as a wide range of other fields and disciplines.
When Paul heard that a Christ-follower in Corinth was in an incestuous relationship with his stepmother, the apostle insisted the man be removed immediately from the congregation. This dramatic response is surprising, as Paul responds to other serious situations with much less vehemence. Why did Paul react to the immoral man with such urgency and severity? Using socio-cultural tools, this study explains the importance of group identity and witness for Paul’s ecclesiology. The argument lays a foundation for contemporary readers to appraise contexts where an expulsive response to sin might be appropriate.
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A "who’s who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers.
Cloud storage services and NoSQL systems typically offer only "Eventual Consistency", a rather weak guarantee covering a broad range of potential data consistency behavior. The degree of actual (in-)consistency, however, is unknown. This work presents novel solutions for determining the degree of (in-)consistency via simulation and benchmarking, as well as the necessary means to resolve inconsistencies leveraging this information.
Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!
Do humans have a special capacity designed to foster experiences of God? What role do specific bodily actions or emotions play in the cultivation of a divine experience? Prayer as Divine Experience in 4 Ezra and John’s Apocalypse: Emotion, Empathy, and Engagement with God explores these questions in a systematic study of the emotions in two apocalyptic texts. The book of 4 Ezra, an ancient Jewish apocalypse, and the book of Revelation, an ancient Christian Apocalypse written by John, are examined with a focus on the emotional language of the prayers and prayer preludes contained in this literature. Both texts were composed in the first-century of the Common Era, a time when most people exposed to literature heard the content as it was recited. The emotive language in these writings could potentially arouse similar emotions in the readers or hearers of these texts, allowing the person to have access to the divine experiences, which are described by the seer in 4 Ezra and are expressed by the angelic choir in John’s Apocalypse. Prior to examining the prayers, Prayer as Divine Experience will describe the neurological processes that cause a person to mirror the emotions expressed by another individual, thereby prompting an imitation of the experience that is perceived.
Osteoarthritis is a common disorder of the joints that affects more than 2 million people in the UK, and studies suggest that this number will double in the next 20 years. The condition is strongly associated with ageing and is believed to affect up to 30% of people over 60 years of age. There are a number of misconceptions surrounding osteoarthritis and this, combined with the lack of effective drug treatments, often leaves patients dispirited and confused about their condition. Osteoarthritis: The Facts helps patients and their carers better understand their condition with a view towards self-management. The text is designed to be easy to read and is organized into two main parts. Part 1 details what osteoarthritis is, what causes it, who it affects, what the main symptoms are, how it is diagnosed and what the long-term outcome is. Part 2 summarises the current management of osteoarthritis, including the role of exercise, diet, medication, "nutriceuticals", alternative therapies, and surgery. The book also includes a useful resources section, including information on support groups, websites, and further reading.
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
THE WORLD'S #1 SURGERY TEXT--UPDATED TO INCLUDE STATE-OF-THE-ART EVIDENCE-BASED SURGICAL CARE AND LEADERSHIP GUIDANCE FOR TRAINEES AND PRACTICING SURGEONS The Tenth Edition of Schwartz's Principles of Surgery maintains the book's unmatched coverage of the foundations of surgery while bringing into sharper focus new and emerging technologies. We have entered a new era of surgery in which minimally invasive surgery, robotic surgery, and the use of computers and genomic information have improved the outcomes and quality of life for patients. With these advances in mind, all chapters have been updated with an emphasis on evidence-based, state-of-the-art surgical care. An exciting new chapter, "Fundamental Principles of Leadership Training in Surgery," expands the scope of the book beyond the operating room to encompass the actual development of surgeons. This edition is also enriched by an increased number of international chapter authors and a new chapter on Global Surgery. More than ever, Schwartz's Principles of Surgery is international in scope--a compendium of the knowledge and technique of the world's leading surgeons. Features More clinically relevant than ever, with emphasis on high-yield discussion of diagnosis and treatment of surgical disease, arranged by organ system and surgical specialty Content is supported by boxed key points, detailed anatomical figures, diagnostic and management algorithms, and key references Beautiful full-color design
The #1 surgical practice and education resource -- completely updated and now in full-color! A Doody's Core Title ESSENTIAL PURCHASE for 2011! 4 STAR DOODY'S REVIEW! "In its evolution over nine editions, Schwartz's Principles of Surgery has reflected the latest in surgical practice. In the age of minimally invasive surgery, illustrations are important and these authors include a wealth of visual material of good to excellent quality."--Doody's Review Service Written by the world's foremost practitioners and instructors, this landmark reference logically progresses from basic science principles, including topics such as cells, genomics, and molecular surgery, to clinical areas such as pancreas. From cover to cover, the book reflects a distinctly modern approach in the dissemination of surgical knowledge, providing up-to-date coverage of all key surgical areas, from trauma and transplantation, to neurosurgery. In each chapter, this content is supported by a skill-building format that includes boxed key points, detailed anatomical figures, diagnostic and management algorithms, an abundance of informative tables, and key references. For every kind of procedure, this one-of-a-kind clinical companion helps you meet the sequential demands in the care of surgical patients, leading to the best possible outcomes. NEW TO THIS EDITION: Full color design for easier navigation 2 new chapters: “Accreditation Council for Graduate Medical Core Competencies,” examines the six areas designated as critical for general surgery resident training and “Ethics, Palliative Care, and Care at the End of Life,” offers an overview of biomedical ethics, and surveys specific issues in surgical and professional ethics, the general principles and considerations of palliative care, and care at the end of life Greater focus on evidence-based medicine with highlighted references in each chapter and separate key reference list Increased number of treatment and diagnostic algorithms Key points in every chapter International advisory board comprising renowned surgeons contributes important regional feedback on content and curricula Companion DVD of surgical video clips
Not-a-pe-ka-gon was the Native American name given to the Ludington area and translates as "heads on sticks." The name refers to a battle between the Ottawa and Mascouten Indians in the 17th century that raged along the river toward Lake Michigan. The heads of the defeated Mascoutens were placed on sticks as a warning to all. Later a bluff overlooking the lake and river was the site of the 1675 death of Fr. Jacques Marquette, a Jesuit missionary and explorer. When the first settlers of European descent arrived, they gave the name of Pere Marquette to their village, lake, and river in honor of the fallen missionary. Eventually renamed after lumber baron James Ludington, the community became a bustling maritime port and the home of the largest car ferry fleet in the world. David K. Petersen is a local historian and collector of historical images. He has published two pictorial books of the Pere Marquette car ferries based on the photography of Erhardt Peters and currently writes a weekly history column for the Ludington Daily News. Petersen has selected many unique images from his collection to illustrate the maritime history of Ludington from its humble beginnings to an important port of call. The Images of America series celebrates the history of neighborhoods, towns, and cities across the country. Using archival photographs, each title presents the distinctive stories from the past that shape the character of the community today. Arcadia is proud to play a part in the preservation of local heritage, making history available to all.
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