David Hurst has a unique knowledge of organizationsÑtheir function and their failureÑboth in theory and in practice. He has spent twenty-five years as an operating manager, often in crises and turnaround conditions, and is also a widely experienced consultant, teacher, and writer on business. This book is his innovative integration of management practice and theory, using a systems perspective and analogies drawn from nature to illustrate groundbreaking ideas and their practical application. It is designed for readers unfamiliar with sophisticated management concepts and for active practitioners seeking to advance their management and leadership skills. HurstÕs objective is to help readers make meaning from their own management experience and education, and to encourage improvement in their practical judgment and wisdom. His approach takes an expansive view of organizations, connecting their development to humankindÕs evolutionary heritage and cultural history. It locates the origins of organizations in communities of trust and follows their development and maturation. He also crucially tracks the decline of organizations as they age and shows how their strengths become weaknesses in changing circumstances. HurstÕs core argument is that the human mind is rational in an ecological, rather than a logical, sense. In other words, it has evolved to extract cues to action from the specific situations in which it finds itself. Therefore contexts matter, and Hurst shows how passion, reason, and power can be used to change and sustain organizations for good and ill. The result is an inspirational synthesis of management theory and practice that will resonate with every readerÕs experience.
For the first time, a seasoned business executive and avid golfer combines these two passions to explore what makes for top performance in each field. Management consultant David K. Hurst explores compelling links relating the two activities to explain clearly what every manager who plays golf may feel only intuitively: that there is a deep systemic connection between them. For on the tee, as in the boardroom, a player can't just hit and hope -- he or she must continually think ahead, contemplate multiple scenarios, and consider the downside of every decision. And then everything depends on execution. In Learning from the Links, Hurst clarifies muddled thinking in both management and golf: he deals squarely with the challenge of implementing a game plan and seeing it through. Hurst takes to task the current "head-down" instructional model used to teach golf and management. He addresses the huge gulf between knowing what to do in a given situation and knowing how to do it. This chasm is an ever-present hazard both on the course and in an organization: it keeps people from solving their problems and achieving their goals. By examining golfers' and managers' struggles for improvement, Hurst shows us why complex systems are so hard to change and how to set about changing them -- systematically. Using the latest thinking from fields as diverse as neuroscience, artificial intelligence, art, and anthropology, Hurst's primary purpose is to help his readers make sense of their own experience -- to help them learn more effectively. His practical advice is profusely illustrated with examples from both golf and management, allowing the reader to move back and forth between his or her experiences in both activities. Part business management book, part strategy guide, these are more than just lessons for one's game or one's office: these are lessons for life.
There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional genomics. This is followed by a series of disease-specific chapters that review epidemiology, natural history, monogenic determinants, complex disease components, disease management, and likely future developments. Respiratory Genetics is an essential reference for pulmonologists, translational researchers, and clinical geneticists, and the text will also be a useful library reference.
Changes in sea level caused by global warming can be disastrous to modern civilization. Therefore, it is important to use accurate and reliable methods to monitor any change. During this century, and, in particular, the last three decades, tide-gauge records have been used to show these changes related to the world's oceans. Aubrey and Emery suggest, however, that tidal gauges should not be used unquestioningly as a benchmark for measuring eustatic sea-level changes. Tectonism, subsidence, ocean current variability, and human activity can, and do, affect the accuracy of these records. Understanding the reasons for changes in land and sea levels is essential for the proper development of coastal regions. The results of this study provide guiding data for scientific, engineering, and policy solutions to coastal flooding. Determining the true causes of relative subsidence, and how to use geological and oceanological controls, will allow us to exist within our natural environment, rather than force nature to conform to our legal and temporary 'remedies.
Fundamentals of Molecular Mycology provides a complete overview of recent developments and applications in molecular mycology. It serves as a comprehensive guide for the identification of fungi and the application of fungal biomolecules in agriculture, food, environment, and pharmaceutical sectors by providing detailed information about application
The landmark text that belongs in the hands of every cardiologist―fully updated and reorganized to make it more patient-centric than ever A Doody's Core Title for 2023! World-famous for its authority and clinical relevance, Fuster and Hurst’s The Heart is cardiology’s longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classic offers a solid foundation in cardiovascular medicine and complete coverage of all major cardiovascular topics. This fifteenth edition presents a greater focus on the practicalities of patient care. Additionally, the content is ordered in a more methodical pattern, from mechanism to management. Reflecting the latest technical, therapeutic, and clinical advances, Fuster and Hurst’s The Heart provides invaluable concise summaries of major new trials and guidelines. Authoritative Coverage and Unmatched Utility: Central Illustrations New section on cardiovascular critical care New chapter "Cardiovascular Disease and COVID-19" Chapter summaries ACC/AHA/ESC guidelines in all chapters 1,200+ photos and illustrations Sections Include: Risk Factors for Cardiovascular Disease Atherosclerosis and Coronary Heart Disease Diseases of the Great Vessels and Peripheral Vessels Valvular Heart Disease Rhythm and Conduction Abnormalities Heart Failure Diseases of the Pericardium Cardiopulmonary Disease Critical Cardiovascular Care Adult Congenital Heart Disease Special Populations and Topics in Cardiovascular Disease
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
For the first time, a seasoned business executive and avid golfer combines these two passions to explore what makes for top performance in each field. Management consultant David K. Hurst explores compelling links relating the two activities to explain clearly what every manager who plays golf may feel only intuitively: that there is a deep systemic connection between them. For on the tee, as in the boardroom, a player can't just hit and hope -- he or she must continually think ahead, contemplate multiple scenarios, and consider the downside of every decision. And then everything depends on execution. In Learning from the Links, Hurst clarifies muddled thinking in both management and golf: he deals squarely with the challenge of implementing a game plan and seeing it through. Hurst takes to task the current "head-down" instructional model used to teach golf and management. He addresses the huge gulf between knowing what to do in a given situation and knowing how to do it. This chasm is an ever-present hazard both on the course and in an organization: it keeps people from solving their problems and achieving their goals. By examining golfers' and managers' struggles for improvement, Hurst shows us why complex systems are so hard to change and how to set about changing them -- systematically. Using the latest thinking from fields as diverse as neuroscience, artificial intelligence, art, and anthropology, Hurst's primary purpose is to help his readers make sense of their own experience -- to help them learn more effectively. His practical advice is profusely illustrated with examples from both golf and management, allowing the reader to move back and forth between his or her experiences in both activities. Part business management book, part strategy guide, these are more than just lessons for one's game or one's office: these are lessons for life.
David Hurst has a unique knowledge of organizationsÑtheir function and their failureÑboth in theory and in practice. He has spent twenty-five years as an operating manager, often in crises and turnaround conditions, and is also a widely experienced consultant, teacher, and writer on business. This book is his innovative integration of management practice and theory, using a systems perspective and analogies drawn from nature to illustrate groundbreaking ideas and their practical application. It is designed for readers unfamiliar with sophisticated management concepts and for active practitioners seeking to advance their management and leadership skills. HurstÕs objective is to help readers make meaning from their own management experience and education, and to encourage improvement in their practical judgment and wisdom. His approach takes an expansive view of organizations, connecting their development to humankindÕs evolutionary heritage and cultural history. It locates the origins of organizations in communities of trust and follows their development and maturation. He also crucially tracks the decline of organizations as they age and shows how their strengths become weaknesses in changing circumstances. HurstÕs core argument is that the human mind is rational in an ecological, rather than a logical, sense. In other words, it has evolved to extract cues to action from the specific situations in which it finds itself. Therefore contexts matter, and Hurst shows how passion, reason, and power can be used to change and sustain organizations for good and ill. The result is an inspirational synthesis of management theory and practice that will resonate with every readerÕs experience.
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