This is the ideal resource for all those requiring an authoritative and up-to-date review of imaging appearances of diseases of the lung, pleura and mediastinum. Chest radiography and CT are integrated with other imaging techniques, including MRI and PET, where appropriate. The clinical and pathologic features of different diseases are provided in varying degrees of detail with more in depth coverage given to rarer and less well understood conditions. A single volume, comprehensive reference text on chest radiology.Provides in a single resource all of the information a generalist in diagnostic radiology needs to know. Concisely and clearly written by a team of 4 internationally recognized authors.Avoids the inconsistency, repetition, and unevenness of coverage that is inherent in multi-contributed books. Multimodality coverage integrated throughout every chapter.All of the applicable imaging modalities are covered in a clinically relevant, diagnostically helpful way. Approximately 3,000 high quality, good-sized images.Provides a complete visual guide that the practitioner can refer to for help in interpretation and diagnosis. Covers both common and uncommon disorders.Provides the user with a single comprehensive resource, no need to consult alternative resources. Access the full text online and download images via Expert Consult Access the latest version of the Fleischner Society's glossary of terms for thoracic imaging. Outlines, summary boxes, key points used throughout.Makes content more accessible by highlighting essential information. Brand new color images to illustrate Functional imaging techniques.Many of the new imaging techniques can provide functional as well as anatomic information. Introduction of a second color throughout in summary boxes in order to better highlight key information. There’s a wealth of key information in the summary boxes—will be highlighted more from the narrative text and will therefore be easier to access. Practical tips on identifying anatomic variants and artefacts in order to avoid diagnostic pitfalls.Many misdiagnoses are the result of basic errors in correlating the anatomic changes seen with imaging to their underlying pathologic processes. Latest techniques in CT, MRI and PET as they relate to thoracic diseases. The pace of development in imaging modalities and new applications/refined techniques in existing modalities continues to drive radiology forward as a specialty. Emphasis on cost-effective image/modality selection.Addresses the hugely important issue of cost-containment by emphasizing which imaging modality is helpful and which is not in any given clinical diagnosis. COPD and Diffuse Lung Disease, Small Airway disease chapters extensively up-dated. Access the full text online and download images via Expert Consult Access the latest version of the Fleischner Society's glossary of terms for thoracic imaging.
Polycystine radiolaria are exclusively marine protists and are found in all ocean waters, from polar regions to the tropics, and at all water depths. There are approximately 600 distinct described living species and several thousand fossil species of polycystines. Radiolarians in general, and polycystines in particular, have recently been shown to be a major component of the living plankton and important to the oceanic carbon cycle. As fossils radiolarians are also fairly common, and often occur in sediments where other types of fossils are absent. This has made them very valuable for certain types of geologic research, particularly estimating the geologic age of the sediments containing them, and as guides to past oceanic water conditions. As our current understanding of the biology, and even taxonomy of the living fauna is still very incomplete, evolutionary studies based on living polycystines are still rare. However, the common occurrence of numerous specimens for many species, and in a wide variety of oceanic environments, provides an excellent opportunity to study the processes of biologic evolution in the fossil record. Paleobiology of the Polycystine Radiolaria is the first major book on radiolarians to appear in the western literature since 2001. Focusing on living and fossil siliceous shelled radiolarians, it is notable for its emphasis not upon morphologic or taxonomic detail but on concepts and applications. The book attempts to provide a balanced, critical review of what is known of the biology, ecology, and fossil record of the group, as well as their use in evolutionary, biostratigraphic and paleoceanographic research. Full chapters on the history of study, and molecular biology, are the first ever in book form. Written for an audience of advanced undergraduate to doctoral students, as well as for a broad range of professionals in the biological and Earth sciences, Paleobiology of the Polycystine Radiolaria summarizes current understanding of the marine planktonic protist group polycystine radiolaria, both in living and fossil form.
Introducing an all-inclusive guide to imaging of the diseased lung. Fr om start to finish, this text takes the reader from fundamental princi ples to sophisticated imaging techniques. Topics covered include the i maging of diffuse infiltrative lung disease; airway disease; emphysema; pulmonary vascular disease; and pediatric diffuse lung disease. The text also discussed the clinical-radiologic consultation.
Published in 1981, this book describes and critically examines the standardised tests and modes of assessment available and most commonly used by speech therapists, psychologists and educationalists. Tests and other assessment procedures are discussed and therapeutic strategies suggested. Thus, psycholinguistic approaches such as ITPA, the Reynell Developmental Language Scales and the Aston Index; linguistic techniques such as LARSP and phonological assessments are described, and adult disorders as well as childhood problems, are reviewed. There is also a brief consideration of the problem of assessing the language of those not speaking English as a first language. The book serves as a core text for student speech therapists and also as a reference for those practicing or researching in speech therapy, special education and linguistic pathology.
A collection of the theories, practices, and policies of vocational education and training written by international experts The Wiley Handbook of Vocational Education and Training offers an in-depth guide to the theories, practices, and policies of vocational education and training (VET). With contributions from a panel of leading international scholars, the Handbook contains 27 authoritative essays from a wide range of disciplines. The contributors present an integrated analysis of the complex and dynamic field of VET. Drawing on the most recent research, thinking, and practice in the field, the book explores the key debates about the role of VET in the education and training systems of various nations. The Handbook reveals how expertise is developed in an age of considerable transformation in work processes, work organization, and occupational identities. The authors also examine many of the challenges of vocational education and training such as the impact of digital technologies on employment, the demand for (re)training in the context of extended working lives, the emergence of learning regions and skill ecosystems, and the professional development of vocational teachers and trainers. This important text: Offers an original view of VET’s role in both the initial and continuing development of expertise Examines the theories and concepts that underpin international perspectives and explores the differences about the purposes of VET Presents various models of learning used in VET, including apprenticeship, and their relationship with general education Explores how VET is shaped in different ways by the political economy of different countries Reviews how developments in digital technologies are changing VET practice Discusses the challenges for universities offering higher vocational education programs Draws on both recent research as well as historical accounts Written for students, researchers, and scholars in the fields of educational studies, human resource development, social policy, political economy, labor market economics, industrial relations, sociology, The Wiley Handbook of Vocational Education and Training offers an international perspective on the topic of VET.
South Africa in Transition utilises new theoretical perspectives to describe and explain central dimensions of the democratic transition in South Africa during the late 1980s and early 1990s, covering changes in the politics of gender and education, the political discourses of the ANC, NP and the white right, constructions of identity in South Africa's black townships and rural areas, the role of political violence in the transition, and accounts of the democratization process itself.
This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.
With the newer ablative and non-ablative techniques offering precise methods for improving photo-aged skin, facial skin rejuvenation is particularly popular. Ablative and Non-Ablative Facial Skin Rejuvenation discusses the various lasers, light sources, and radio-frequency devices currently used. Each chapter analyzes one of the available technolog
Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain. Who should buy this book? Pharmacology of Pain is a particularly useful resource for: Basic researchers and clinicians, including physicians, dentists, pharmacists, nurses, and physical therapists Other professionals in the field of pain research and treatment Students and trainees
The writings of Newton, Leibniz, Pascal, Riemann, Bernoulli, and others in a comprehensive selection of 125 treatises dating from the Renaissance to the late 19th century — most unavailable elsewhere. Grouped in five sections: Number; Algebra; Geometry; Probability; and Calculus, Functions, and Quaternions. Includes a biographical-historical introduction for each article.
Molecular biology is one of the most rapidly growing developing and at the same time most exciting disciplines. The key to molecular biology lies in the understanding of nucleic acids - their structure, function, and interaction with proteins. Nucleic Acids in Molecular Biology keeps scientists informed of the explosively growing information and complies with the great interest in this field by offering a continued high standard of review.
High Resoultion CT of the lung is the market leading reference for HRCT of the lung. Its easy-to-use format includes illustrated "quick-reference guide" to help readers navigate the text along with diagnostic algorithms and numerous tables to identify key findings, abbreviations used, and other essential information. The book guides the reader through the details of the numerous HRCT findings and their differential diagnosis and reviews characteristics of the common lung diseases. Discussion includes normal anatomy, HRCT findings, multiple examples of disease entities, radiologic-pathologic correlations, and rare diseases and their differential diagnosis.
This work brings together a selection of Clinical Forum features from the journal "Aphasiology". The fora are designed to cover issues in clinical aphasiology which are central, topical and controversial. Each forum concerns a main article and a number of commentaries.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.
The Second Edition of Pharmacotherapy for Child and Adolescent Psychiatric Disorders contains new and expanded chapters on combination therapy pharmacoepidemiology pharmacoeconomics current social, ethical, and legal issues surrounding the administration of psychostimulants and antidepressants to children and teenagers serotonin reuptake inhibitors and discusses techniques to select the most appropriate drug and dosing schedule methods to adjust safely and tailor medical treatments for children during various stages of growth and development the effect of psychoactive drugs on cardiac function Offering nearly 3000 contemporary references to facilitate further research, Pharmacotherapy for Child and Adolescent Psychiatric Disorders, Second Edition is a timely and authoritative guide suitable for psychiatrists, psychologists, pediatricians, pharmaceutical and behavioral scientists, clinical neurologists, primary care physicians, social workers, and graduate and medical school students in these disciplines.
A comparison of the cultural and political/institutional dimensions of war's impact on Greece during the Peloponnesian War, and the United States and the two Koreas, North and South, during the Korean War. It demonstrates the many underlying similarities between the two wars.
This two-volume text provides a summary of studies relating to the use of photosensitizing agents in the diagnosis and therapy of cancer. This interesting work describes synthesis of new sensitizers, photochemical and photobiological properties of dyes currently used for photodynamic therapy, plus those being examined with a view toward providing therapeutic advantages. It contains results and methodology from leading experts on the use of porphyrins and other photosensitizers for detection of neoplastic disease and for photodynamic therapy of neoplastic disease. The volumes focus on the major clinical and pre-clinical research groups. They also include an appended bibliography which lists all pertinent publications in this field. This easy-to-understand book is written for all workers in the field of photodynamic therapy and provides an introduction to those beginning research on some aspect of tumor photosensitization.
Understanding the molecular mechanism of muscle contraction started with the discovery that striated muscle is composed of interdigitating filaments which slide against each other. Sliding filaments and the working-stroke mechanism provide the framework for individual myosin motors to act in parallel, generating tension and loaded shortening with an efficient use of chemical energy. Our knowledge of this exquisitely structured molecular machine has exploded in the last four decades, thanks to a bewildering array of techniques for studying intact muscle, muscle fibres, myofibrils and single myosin molecules. After reviewing the mechanical and biochemical background, this monograph shows how old and new experimental discoveries can be modelled, interpreted and incorporated into a coherent mathematical theory of contractility at the molecular level. The theory is applied to steady-state and transient phenomena in muscle fibres, wing-beat oscillations in insect flight muscle, motility assays and single-molecule experiments with optical trapping. Such a synthesis addresses major issues, most notably whether a single myosin motor is driven by a working stroke or a ratchet mechanism, how the working stroke is coupled to phosphate release, and whether one cycle of attachment is driven by the hydrolysis of one molecule of ATP. Ways in which the theory can be extended are explored in appendices. A separate theory is required for the cooperative regulation of muscle by calcium via tropomyosin and troponin on actin filaments. The book reviews the evolution of models for actin-based regulation, culminating in a model motivated by cryo-EM studies where tropomyosin protomers are linked to form a continuous flexible chain. It also explores muscle behaviour as a function of calcium level, including emergent phenomena such as spontaneous oscillatory contractions and direct myosin regulation by its regulatory light chains. Contraction models can be extended to all levels of calcium-activation by embedding them in a cooperative theory of thin-filament regulation, and a method for achieving this grand synthesis is proposed. Dr. David Aitchison Smith is a theoretical physicist with thirty years of research experience in modelling muscle contractility, in collaboration with experimental groups in different laboratories.
Interest in the humane and scientifically justifiable use of research animals has intensified since the publication of the 2nd edition of Animal Models in Cardiovascular Research. This completely revised and updated edition will provide information essential to any researcher interested in using animal models for cardiovascular research, or any research which requires normal cardiovascular function. The format and presentation will be changed to make the text more easy to read and use: (1) This edition is in outline format, for ease and utility. (2) The opening chapter includes more information on the cardiovascular effects of post-operative analgesia and will address the recognition of pain behavior in species commonly used in research settings, particularly rats and mice. (3) New edition includes reference material more useful to researchers using transgenic and naturally occurring animal models to dissect these mechanisms.
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.
Newly updated, this full-color resource offers a systematic approach to performing a neuromusculoskeletal assessment with rationales for various aspects of the assessment. This comprehensive text covers every joint of the body, head and face, gait, posture, emergency care, the principles of assessment, and preparticipation evaluation. The latest edition of this core text is the essential cornerstone in the new four-volume musculoskeletal rehabilitation series. Thorough, evidence-based content provides the information and detail you need to select the best diagnostic tests. Extensively updated information incorporates the latest research and most current practices. Case Studies help you apply what you learn from the book to real life situations. Tables and boxes throughout the text organize and summarize important information and highlight key points. Chapter Summaries review the assessment procedures for each chapter to help you find important information quickly. Case Histories in each chapter demonstrate assessment skills to help you apply them in practice. Reliability and validity of tests and techniques included throughout help you choose assessment methods supported by current evidence. A new full-color design clearly demonstrates assessment methods, a variety of tests, and causes of pathology. A Companion CD-ROM with all of the references from the text linked to MedLine abstracts reinforces concepts from the book. Primary Care Assessment chapter includes the latest information on the constantly evolving state of physical therapy practice. Includes the most current information on the assessment of the cervical spine, hip, posture, and foot and ankle to keep you up to date on current methods of practice.
Transplant Infections is a practical, clinically focused reference covering the common and more unusual bacterial, viral, and fungal infections affecting patients who have received stem cell or solid organ transplants. It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. Highlights of the Third Edition include a chapter on new immunosuppressive agents and expanded coverage of tropical infections and West Nile virus.
Highly Commended, BMA Medical Book Awards 2013Previously published as Textbook of Clinical Neuropsychiatry, this book has been re-titled and thoroughly updated, redesigned, and enhanced to include the fundamentals of neuroscience. This highly acclaimed text provides a definitive, clinically oriented, yet comprehensive book covering neuropsychiatry
Providing a solid foundation in clinical medicine for optometrists and optometry students, Clinical Medicine for Optometrists covers the systemic medical conditions that have serious impacts on ocular health and function, as well as the ocular exam findings that may be an early indication of significant systemic disease. This unique text explains important medical considerations for optometric practice, meeting the needs of clinical medicine courses in optometry programs, and also serving as a practical reference for optometrists in practice.
Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.
Over the past 30 years high-resolution CT (HRCT) has matured to become an integral part of the multidisciplinary evaluation in diffuse lung disease. In this regard, Webb, Muller and Naidich’s High-Resolution CT of the Lung, 6th Edition, is a ‘gold standard’ reference that aims to keep radiologists and pulmonologists alike at the cutting edge of the ever-evolving field of thoracic imaging. The new US-European author team continues the tradition of excellence which readers have come to expect while the underlying layout and ethos — established by the ‘founding’ author team — remain. The new edition aims to brings readers up to date not only with recent advances but also with the important conceptual changes in thinking in various fields of thoracic imaging. Also featured in this updated edition is authoritative guidance on HRCT findings and differential diagnosis, as well as the characteristics of the common lung diseases assessed using HRCT, all enhanced by a multitude of new images and updated content throughout.
After diabetic retinopathy, the varieties of retinal vein occlusion constitute the most prevalent category of retinal vascular disease. For macular edema associated with central retinal vein occlusion (CRVO), no effective therapy existed until 2009, despite decades of research and failed pilot therapies. This comprehensive, illustrated text integrates recent advances in treatments with the parallel progress in understanding of disease mechanisms. Complete with case studies, this text is perfect for retina specialists, ophthalmologists, optometrists, and residents and fellows in these fields.
For 125 years, physicians have relied on Manson's Tropical Diseases for a comprehensive clinical overview of this complex and fast-changing field. The fully revised 24th Edition, Dr. Jeremy Farrar, along with an internationally recognized editorial team, global contributors, and expert authors, delivers the latest coverage on parasitic and infectious diseases from around the world. From the difficult to diagnose to the difficult to treat, this highly readable, award-winning reference prepares you to effectively handle whatever your patients may have contracted. - Covers all of tropical medicine in a comprehensive manner, general medicine in the tropics, and non-clinical issues regarding public health and ethics. - Serves as an indispensable resource for physicians who treat patients with tropical diseases and/or will be travelling to the tropics, or who are teaching others in this area. - Contains a new section on 21st Century Drivers of Tropical Medicine, with chapters covering Poverty and Inequality, Public Health in Settings of Conflict and Political Instability, Climate Change, and Medical Product Quality and Public Health. - Includes all-new chapters on Surgery in the Topics, Yellow Fever, Systemic Mycoses, and COVID-19. - Covers key topics such as drug resistance; emerging and reemerging infections such as Zika, Ebola, and Chikungunya; novel diagnostics such as PCR-based methods; point-of care-tests such as ultrasound; public health in settings of conflict and political instability; and much more. - Differentiates approaches for resource-rich and resource-poor areas. - Includes reader-friendly features such as highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.
Metabolic and cellular engineering, as presented in this book, is a powerful alliance of two technologies: genetics-molecular biology and fermentation technology. Both are driven by continuous refinement of the basic understanding of metabolism, physiology and cellular biology (growth, division, differentiation), as well as the development of new mathematical modeling techniques. The authors' approach is original in that it integrates several disciplines into a coordinated scheme, i.e. microbial physiology and bioenergetics, thermodynamics and enzyme kinetics, biomathematics and biochemistry, genetics and molecular biology. Thus, it is called a transdisciplinary approach (TDA). The TDA provides the basis for the rational design of microorganisms or cells in a way that has rarely been utilized to its full extent.
“French Nobel Laureate Claude Cohen-Tannoudji is second to none in his understanding of the modern theory and application of atom-photon interactions. He is also known for his lucid and accessible writing style … Advances in Atomic Physics is an impressive and wonderful-to-read reference text … Certainly researchers in the fields of atom-photon interactions and atom traps will want it as a reference on their bookshelves … A selection of chapters may be of benefit to students: the early chapters for those entering the field, the later chapters for those already doing atom-laser PhD thesis work.”Physics TodayThis book presents a comprehensive overview of the spectacular advances seen in atomic physics during the last 50 years. The authors explain how such progress was possible by highlighting connections between developments that occurred at different times. They discuss the new perspectives and the new research fields that look promising. The emphasis is placed, not on detailed calculations, but rather on physical ideas. Combining both theoretical and experimental considerations, the book will be of interest to a wide range of students, teachers and researchers in quantum and atomic physics.
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