Based on the lectures given at the Seminaire de Theorie des Nombres de Paris in 1990-1991, this collection of papers reflects work in many areas of number theory, including: cubic exponential sums; Riemann's period relations; and Galois representations attached to points on Shimura varieties.
It is now clear that a binary evolutionary pathway is responsible for a significant fraction of all planetary nebulae, with some authors even going so far as to claim that binarity may be a near requirement for the formation of an observable nebula. This has led to the requirement that textbooks most likely need to be rewritten. Building upon the review of Jones and Boffin in Nature Astronomy (2017), this Springer Brief takes a first step in this direction. It offers the first expanded presentation of all the theoretical and observational support for the importance of binarity in the formation of planetary nebulae, initially focusing on common envelope evolution but also covering wider binaries. This book emphasises the wider impact of the field, highlighting the critical role binary central stars of planetary nebulae have in understanding a plethora of astrophysical phenomena, including type Ia supernovae, chemically peculiar stars and circumbinary exoplanets.
Being change capable is the "new normal" for today’s growth-minded organizations. The "do more with less" strategies of the past are no longer effective in preparing organizations to meet the increasing challenges for growth, competitiveness and innovation required of them in this new era. Business change challenges including customer and market shifts, legal and regulatory requirements, strategic redirection, acquisitions, strategic partnerships, and cultural transformation are demanding that organizations effectively and efficiently manage change across multiple dimensions. To reach this level of change capability, organizations must adopt an integrated, balanced and customized approach to change management. Change management is addressed from the unique perspective of both its foundational concepts as well as practical application. Using an integrated, scalable and flexible framework, this book provides tools which can be readily customized and applied to initiatives across or within stages of the business change management lifecycle, from assessing the need for change, through planning the change initiative, designing a balanced change solution which integrates the people, process, and project management elements, through deploying and institutionalizing the change. Common risks associated with failed or stalled change initiatives are presented with best practices and key topics associated with change management are explored and illustrated through real-life case studies. Aimed at both the professionals within organizations and post graduate students and researchers within business strategy, organizational behaviour and change management disciplines, this book will provide a conceptual understanding of change management and a roadmap with a supporting toolbox for leading and implementing change that sticks.
In the midst of an addiction epidemic, this newly updated edition of The American Society of Addiction Medicine Principles of Addiction Medicine, 5th edition is the sought-after text every addiction researcher and care provider needs. This comprehensive reference text dedicates itself to both the science and treatment of addiction. You’ll receive a thorough grounding in both the scientific principles behind the causes of addiction and the practical aspects of clinical care. Chapters are written by recognized experts, covering areas such as the basic science of addiction medicine; diagnosis, assessment and early intervention; pharmacologic and behavioral interventions; mutual help and twelve-step; and co-occurring addiction, medical and psychiatric disorders—backed by the latest research data and successful treatment methods. Features: Numerous figures, tables and diagrams elucidate the text Chapters include case examples List of data research reports provided at end of each chapter NEW material on Prescription Drug Abuse, Club Drugs, Nursing Roles in Addressing Addiction, Conceptual and Treatment Issues in Behavioral Addictions, Rehabilitation Approaches to Pain Management, Comorbid Pain and Addiction, Pharmacotherapy for Adolescents with Substance Use Disorders, Preventing and Treating Substance Use Disorders in Military Personnel, and more.
The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things atthe molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair,among other subjects. The second edition captures these and other advances, and broadens its scope to address the experimental science of toxicology. The first edition of Molecular Toxicology has become an indispensable resource for graduate students in molecular and biochemical toxicology courses,as well as academic researchers and industrial researchers in toxicology. Rigorously updated and revised, the new edition commands an unrivaled authority in the field of molecular toxicology.
There is a long history of the involvement of animals for tourism purposes in circuses, zoos, fairs, ecotourism and wildlife tourism, using animals as the prime focus of their experience. The wave of responsibility and sustainability that currently permeates the tourism field is catalyzing deeper moral questions about equity, equality, rights, justice, and values in regards to what constitutes acceptable tourism practice. Tourism and Animal Ethics represents a required extension of the sustainability imperative and environmental theory by providing a critical account of the role that animals play in tourism. This book explores the rich history of animal ethics research that lies outside the field of tourism for the purpose of providing greater theoretical, empirical and conceptual guidance inside the field. It examines historical and current practices of the use of animals in the tourism industry from both in situ to ex situ consumption and production perspectives, identifying a range of ethical issues associated with such use. This detailed examination of current animal ethics theories will be instrumental in determining the rightness or wrongness of these practices, and hence allow tourism practitioners and theorists to think about these issues and practices in a different light, minimizing the impact that the industry has on animals. This text provides an interdisciplinary overview of the moral issues related to the use of animals in tourism, and contains cutting edge research and boxed international case studies throughout. It will appeal to students, academics and researchers interested in Tourism Ethics, Sustainable Tourism and Wildlife Tourism.
A compilation of 45 African-American cemeteries in Jackson and Sandy Ridge Townships in Union Co., NC, with eight surrounding townships, in North and South Carolina.
Co-published with the Denver Museum of Nature & Science. Thoroughly revised and updated, Mammals of Colorado, Second Edition is a comprehensive reference on the nine orders and 128 species of Colorado's recent native fauna, detailing each species' description, habitat, distribution, population ecology, diet and foraging, predators and parasites, behavior, reproduction and development, and population status. An introductory chapter on Colorado's environments, a discussion of the development of the fauna over geologic time, and a brief history of human knowledge of Coloradan mammals provide ecological and evolutionary context. The most recent records of the state's diverse species, rich illustrations (including detailed maps, skull drawings, and photographs), and an extensive bibliography make this book a must-have reference. Amateur and professional naturalists, students, vertebrate biologists, and ecologists as well as those involved in conservation and wildlife management in Colorado will find value in this comprehensive volume.
Breast Cancer, Second Editionis intended to provide a comprehensive description of current and evolving aspects of breast cancer including the biologic basis of disease, epidemiology, risk assessment, diagnostic evaluation, treatment strategies, and surveillance measures. The second edition expands considerably on the first edition, containing greater emphasis on issues relevant to medical oncology and the broader oncology community. New to this edition are chapters on the male breast, breast cancer in the augmented breast and breast cancer in multiethnic/multiracial populations. Part of the American Cancer Society’s acclaimedAtlas of Clinical Oncology series, this volume offers an expert overview of breast cancer. Topics range from epidemiology and genetics to diagnosis, management and reconstruction. Post-treatment care, as well as male breast cancer, is also discussed.
Apply engineering and design principles to revitalize the healthcare delivery system Healthcare Systems Engineering is the first engineering book to cover this emerging field, offering comprehensive coverage of the healthcare system, healthcare delivery, and healthcare systems modeling. Written by leading industrial engineering authorities and a medical doctor specializing in healthcare delivery systems, this book provides a well-rounded resource for readers of a variety of backgrounds. Examples, case studies, and thoughtful learning activities are used to thoroughly explain the concepts presented, including healthcare systems, delivery, quantification, and design. You'll learn how to approach the healthcare industry as a complex system, and apply relevant design and engineering principles and processes to advance improvements. Written with an eye toward practicality, this book is designed to maximize your understanding and help you quickly apply toward solutions for a variety of healthcare challenges. Healthcare systems engineering is a new and complex interdisciplinary field that has emerged to address the myriad challenges facing the healthcare industry in the wake of reform. This book functions as both an introduction and a reference, giving you the knowledge you need to move toward better healthcare delivery. Understand the healthcare delivery context Use appropriate statistical and quantitative models Improve existing systems and design new ones Apply systems engineering to a variety of healthcare contexts Healthcare systems engineering overlaps with industrial engineering, operations research, and management science, uniting the principles and practices of these fields together in pursuit of optimal healthcare operations. Although collaboration is focused on practitioners, professionals in information technology, policy and administration, public health, and law all play crucial roles in revamping health care systems. Healthcare Systems Engineering is a complete and authoritative reference for stakeholders in any field.
Nuclear medicine is the bridge between a particular clinical problem and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book to approach the subject from a clinical standpoint, including where necessary relevant physiological material. There exist many excellent texts which cover the basic science and technology of nuclear medicine. We have, therefore, severely limited our coverage of these aspects of the subject to matters which we felt to be essential, particularly those which have been less well covered in other texts - for example, the contents of Chapter 21 on Quantitation by Royal and McNeil. Similarly, we have included at the end of some chapters descriptions of particular techniques where we and the authors felt that it would be helpful. In order to emphasize the clinical approach of this book we have inverted the traditional sequence of material in chapters, presenting the clinical problems first in each instance.
One hundred and five species of mammals are native to the Trans-Pecos region of Texas. The greatly varied terrain, climate, and vegetation make its mammalian life exceptionally varied, ranging from tiny shrews to great elks, from bats to aquatic beavers and muskrats, from desert-dwelling kangaroo rats to forest-loving chipmunks, and from an assortment of mice and rats to predatory cougars and coyotes. This fully revised and updated edition of The Mammals of Trans-Pecos Texas provides a guide to the identification of these animals and summarizes important facts about their lives. With nearly every species illustrated with accurate, detailed pen-and-ink drawings by artist Chester O. Martin and color plates of some of the most iconic mammals that live in the Trans-Pecos region, it exemplifies how biologists integrate art with science to develop a wider appreciation for nature. The account of each species is arranged to contain a brief description of the animal, the geographic distribution of the species, and a discussion of the natural history of the mammal. This authoritative work brings together an appreciation for and understanding of the diversity of fauna, life histories, and ecologies within a unique and fascinating landscape.
This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials. Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods. - Written by leaders in the field of clinical research who have published extensively with authorship of hundreds of articles in medical journals. - The authorship includes one of the three authors of the CONSORT guidelines for the reporting of randomized controlled trials. - The book presents the essential concepts to a wide array of topics including randomized control trials, descriptive studies, cohort studies, case-control studies, bias, and screening tests. - The book utilises a readable and humorous prose style, lightening what can be a difficult area for clinical readers. - Derived from decades of teaching clinical research in seminar settings the book will empower clinicians to make sense of, and critically appraise, current medical research and will enable researchers to enrich the quality of their work. For this Second Edition, the authors have revised and updated the original 16 chapters and added six new chapters. For busy clinicians and active researchers interested in research methods, this book provides helpful tools to derive satisfaction - indeed, fun - from clinical science.
For this issue, Drs. David Della-Giustina and Katja Goldflam have provided an excellent array of topics and authors concerning Orthopedic Emergencies. Articles include: Evaluation and Treatment of the Neck and Cervical Spine, Evaluation and Treatment of Hand Injuries,Evaluation and Treatment of Wrist Injuries,Evaluation and Treatment of Elbow and Forearm Injuries,Evaluation and Treatment of the Shoulder and Humerus, Evaluation and Treatment of Pelvic Injuries, Evaluation and Treatment of Foot and Ankle Injuries, and more!
This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
In spite of improved access to psychosocial interventions, many people with psychosis continue to experience persistent problems which act as significant barriers to their recovery. This book investigates risk and problem behaviours in psychosis including staff and service factors that can impede the delivery of effective care. Working with Problematic Behaviour in Psychosis provides a new approach for assessment formulation and intervention with such problem behaviours in a team context. Of particular interest will be: an outline of the SAFE (Shared Assessment, Formulation and Education) approach an integrative model for understanding risk and problematic behaviour shared risk assessment and management processes the use of CBT in day-to-day interactions with clients a set of formulation driven strategies for managing problematic behaviours case studies and vignettes providing guidance and highlighting the benefits of the approach. This book will have particular appeal to professionals working in residential care for those with complex mental health problems as well as those working in intensive community based services. It is also an excellent resource for those training in psychological therapies for complex mental health problems, risk assessment and management"--Provided by publisher
Providing the academic community with a robust and highly practical insight into the importance of implementing relationship building into the learning environment and experiences of all students, underpinned by current research, this innovative volume explores intercultural learning and critical pedagogy in the borderless university. By revealing cutting-edge theoretical perspectives and practice which can facilitate critical connections between diverse students, their learning, curriculum, each other, and their communities, Learner Relationships in Global Higher Education integrates academic and student perspectives on relationship development into academic practice. Drawing upon case studies and examples of good practice from across the globe, this book illustrates how practitioners in diverse contexts are designing student experiences in face-to-face and online contexts on- and off-campus to advance learner relationships. By situating this work in a critical pedagogy perspective, the book advances internationalisation in and for a global and multicultural world. In the changing contexts of global higher education, this book is a valuable tool for higher education researchers and practitioners at all stages of their careers.
Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Psychiatric comorbidities such as depression, anxiety and substance use are extremely common amongst people with schizophrenia. They add to poor clinical outcomes and disability, yet are often not at the forefront of the minds of clinicians, who tend to concentrate on assessing and treating the core symptoms of schizophrenia, notably delusions and hallucinations. There is an imperative to assess every patient with schizophrenia for psychiatric comorbidities, as they might masquerade as core psychotic symptoms and also because they warrant treatment in their own right. This volume addresses these issues using a clinical lens informed by the current literature. Published as part of the Oxford Psychiatry Library series, the book serves as a concise and practical reference for busy clinicians.
An authoritative resource that offers the statistical tools and software needed to design and plan valid clinical studies Now in its fourth and extended edition, Sample Sizes for Clinical, Laboratory and Epidemiology Studiesincludes the sample size software (SSS) and formulae and numerical tables needed to design valid clinical studies. The text covers clinical as well as laboratory and epidemiology studies and contains the information needed to ensure a study will form a valid contribution to medical research. The authors, noted experts in the field, explain step by step and explore the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their when planned study. The book contains sets of sample size tables with companion explanations and clear worked out examples based on real data. In addition, the text offers bibliography and references sections that are designed to be helpful with guidance on the principles discussed. This revised fourth edition: Offers the only text available to include sample size software for use in designing and planning clinical studies Presents new and extended chapters with many additional and refreshed examples Includes clear explanations of the principles and methodologies involved with relevant practical examples Makes clear a complex but vital topic that is designed to ensure valid methodology and publishable results Contains guidance from an internationally recognised team of medical statistics experts Written for medical researchers from all specialities and medical statisticians, Sample Sizes for Clinical, Laboratory and EpidemiologyStudies offers an updated fourth edition of the important guide for designing and planning reliable and evidence based clinical studies.
Textbook of Clinical Neuropsychiatry provides a comprehensive, encyclopedic and up to date coverage of the complete range of neuropsychiatric disorders. The text is clearly written and well organized, utilizing a consistent and easy to read format throughout. Part I describes the diagnostic assessment of patients and details the interview, mental s
Physiotherapy is arriving at a critical point in its history. Since World War I, physiotherapy has been one of the largest allied health professions and the established provider of orthodox physical rehabilitation. But ageing populations of increasingly chronically ill people, a growing scepticism towards biomedicine and the changing economy of healthcare threaten physiotherapy’s long-held status. Paradoxically, physiotherapy’s affinity for treating the ‘body-as-machine’ has resulted in an almost complete inability to identify the roots of the profession’s present problems, or define possible ways forward. Physiotherapists need to engage in critically informed theoretical discussion about the profession’s past, present and future - to explore their practice from economic, philosophical, political and sociological perspectives. The End of Physiotherapy aims to explain how physiotherapy has arrived at this critical point in its history, and to point to a new future for the profession. The book draws on critical analyses of the historical and social conditions that have made present-day physiotherapy possible. Nicholls examines some of the key discourses that have had a positive impact on the profession in the past, but now threaten to derail it. This book makes it possible for physiotherapists to think otherwise about their profession and their day-to-day practice. It will be essential reading for scholars and students of physiotherapy, interprofessional and community rehabilitation, as well as appealing to those working in medical sociology, the medical humanities, medical history and health care policy.
A new view of the economy as an evolving, complex system has been pioneered at the Santa Fe Institute over the last ten years, This volume is a collection of articles that shape and define this view?a view of the economy as emerging from the interactions of individual agents whose behavior constantly evolves, whose strategies and actions are always adapting.The traditional framework in economics portrays activity within an equilibrium steady state. The interacting agents in the economy are typically homogenous, solve well-defined problems using perfect rationality, and act within given legal and social structures. The complexity approach, by contrast, sees economic activity as continually changing?continually in process. The interacting agents are typically heterogeneous, they must cognitively interpret the problems they face, and together they create the structures?markets, legal and social institutions, price patters, expectations?to which they individually react. Such structures may never settle down. Agents may forever adapt and explore and evolve their behaviors within structures that continually emerge and change and disappear?structures these behaviors co-create. This complexity approach does not replace the equilibrium one?it complements it.The papers here collected originated at a recent conference at the Santa Fe Institute, which was called to follow up the well-known 1987 SFI conference organized by Philip Anderson, Kenneth Arrow, and David Pines. They survey the new study of complexity and the economy. They apply this approach to real economic problems and they show the extent to which the initial vision of the 1987 conference has come to fruition.
Learn the fundamentals and foundations of modern organic chemistry with this comprehensive guide Foundations of Organic Chemistry: Unity and Diversity of Structures, Pathways, and Reactions, 2nd Edition, is a substantive guide for students beginning their study of organic chemistry and instructors, as well as senior undergraduates and graduate students seeking to further their understanding of the subject. Foundations of Organic Chemistry is a serious attempt to show students who want to learn organic chemistry how we know what we know about the subject and to guide them to learn. In this work, the emphasis of the discussion of structures, pathways, and reactions is placed on the original literature and the fundamentals and use of spectroscopic and kinetic tools. Application of the resulting working knowledge of the substance of organic chemistry will lead the serious student to ask additional questions and, ultimately, to solve problems we face. The book also includes solutions guides for instructors and lecturers, as well as access to a companion website for furthering the reader’s knowledge of organic chemistry.
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