This Intergovernmental Panel on Climate Change Special Report is the most comprehensive assessment available on the effects of aviation on the global atmosphere. The report considers all the gases and particles emitted by aircraft that modify the chemical properties of the atmosphere, leading to changes in radiative properties and climate change, and modification of the ozone layer, leading to changes in ultraviolet radiation reaching the Earth. This volume provides accurate, unbiased, policy-relevant information and is designed to serve the aviation industry and the expert and policymaking communities.
There are few episodes in American history as interesting and controversial as the Salem Witch Trials. This work provides a revealing analysis of what it was like to live in Massachusetts during that time, creating a nuanced profile of New England Puritans and their culture. What was it like to live in the colony of Massachusetts during the last decade of the 17th century, the decade famed for the Salem Witch Trials? Daily Life during the Salem Witch Trials answers that question, offering a vivid portrait essential to anyone seeking to understand the traumatic events of the time in their proper historical context. The book begins with a historical overview tracing the development of the Puritan experiment in the Massachusetts colony from 1620 to 1692. It then explores the cultural values and day-to-day concerns of Puritan society in the late-17th century, including trends and patterns of behavior in family life, household activities, business and economics, political and military responsibilities, and religious belief. Each chapter interprets a different aspect of daily life as it was experienced by those who lived through the social crisis of the witch trials of 1692–93, helping readers better comprehend how the history-making events of those years could come to pass.
A candid explanation of how the labor market really works and is central to everything—and why it is not as healthy as we think Relying on unemployment numbers is a dangerous way to gauge how the labor market is doing. Because of a false sense of optimism prior to the COVID-19 shock, the working world was more vulnerable than it should have been. Not Working is about how people want full-time work at a decent wage and how the plight of the underemployed contributes to widespread despair, a worsening drug epidemic, and the unchecked rise of right-wing populism. David Blanchflower explains why the economy since the Great Recession is vastly different from what came before, and calls out our leaders for their continued failure to address one of the most unacknowledged social catastrophes of our time. This revelatory and outspoken book is his candid report on how the young and the less skilled are among the worst casualties of underemployment, how immigrants are taking the blame, and how the epidemic of unhappiness and self-destruction will continue to spread unless we deal with it. Especially urgent now, Not Working is an essential guide to strengthening the labor market for all when we need it most.
To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.
How do volcanoes erupt, what makes earthquakes so destructive, and why do tsunamis happen? Volcanoes, Earthquakes and Tsunamis answers these questions and more, giving you everything you need to know about these powerful natural phenomena. It covers the plate tectonic background to Earth processes, where magma is made and how it erupts, volcano types, eruption hazards and how they are monitored, faults and earthquakes, the causes of tsunamis and tsunami preparedness. You will examine many examples of these frightening events, find out to what extent they can be predicted and mitigated against, and come to realize how they are related and the impact they have on human society and the natural world. Written by Dr David Rothery, a volcanologist, geologist, planetary scientist and Professor of Planetary Geosciences at the Open University, Volcanoes, Earthquakes and Tsunamis: A Complete Introduction is designed to give you everything you need to know, all in one place. It covers the key areas that students are expected to be confident in, outlining the basics in clear English and providing added-value features like a glossary of essential terms and even examples of questions you might be asked in your seminar or exam. The book covers the essentials of most university courses, with an introduction on how the Earth moves, followed by separate sections on volcanoes (including eruptions, types of volcano, volcanic hazards, volcanoes and climate, monitoring volcanoes, predicting eruptions and living with volcanoes), earthquakes (including faults, measurement, seismic monitoring, prediction, prevention and preparedness) and tsunamis. The colour plates referred to in the book can be downloaded from the Teach Yourself online library or accessed through the Teach Yourself Library app.
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
One of nature's most awesome phenomena, volcanoes are endlessly fascinating. Now you don't have to be a scientist to understand the different types of volcanoes. Teach Yourself Volcanoes explains why eruptions occur, how volcanoes are monitored, how eruptions are predicted, and more. Includes suggested destinations for viewing real-life volcanic activity.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
This fifth edition of a classic and comprehensive resource presents an applied, realistic view of entrepreneurial finance for today’s entrepreneurs, completely updated to address the latest trends and technologies. The book provides an integrated set of concepts and applications, drawing from entrepreneurship, finance and accounting, that will prepare aspiring entrepreneurs for the world they will most likely face as they start their new businesses. The contents are designed to follow the life cycle of a new business venture. Topics are presented in logical order, as entrepreneurs will likely face them as they begin the process of business start-up and move into growing the business. Both undergraduate and graduate students will appreciate the clear presentation of complex issues, and this book is an essential resource for budding entrepreneurs as well. A comprehensive spreadsheet financial template is included with the book, and an all-new case study provides questions that will help students learn the template as they proceed through the book. This tool allows for the application of many of the concepts to actual businesses and can be a valuable supplement to the process of developing a full business plan. The spreadsheet financial template is available for unlimited free downloads at Professor Cornwall’s blog site: www.drjeffcornwall.com.
This preeminent book in the field of Neurology has been extensively updated and expanded by 70 leading authorities, providing a single, encyclopedic summary the scientific advances and new clinical practices that can be immediately considered for your patients. It brings together nearly the entire spectrum of motor disorders and Neurology into one convenient resource to aid in a comprehensive evaluation, diagnosis, distinction, and treatment of various disorders. Additionally, by using the perspectives of different subspecialties, the book also provides a comprehensive yet concise account of any disorder with motor manifestations. This new edition now includes the following content and features: Edited by David S. Younger, MD, a highly respected practitioner and researcher, with scholarly chapters by leaders in the field and more international authors than other texts. Up-to-date articles on highly changing subjects related to Neurogenetics. Chapters on Neurorehabilitation – coverage not usually found in other neurological textbooks. Advances in Alzheimer Disease, Parkinson Disease, Amyotophic Lateral Sclerosis. Both adult and pediatric topics in one book. High quality figures of neuroimaging and neuropathology.
Facioscapulohumeral muscular dystrophy (FSHD) is a genetic disorder involving slowly progressive muscle degeneration in which the muscles of the face, shoulder blades and upper arms are among the most severely affected. It is the third most common inherited muscular dystrophy, affecting 1 in 20,000. The search for the molecular basis of the disease is of interest to all genetic researchers, involving a deletion outside a coding region resulting in over-expression of adjacent genes. This volume summarizes the current understanding of the disorder, including clinical, molecular and therapeutic aspects.
The definitive guide to trauma surgery—now in full color! The seventh edition, Trauma reaffirms its status as the leading comprehensive textbook in the field. With a new full-color design and a rich atlas of anatomic drawings and surgical approaches, Trauma, 7e takes you through the full range of injuries the trauma surgeon is likely to encounter. The book also features timely coverage that explains how to care for war victims who may require acute interventions such as amputation. Supported by numerous x-rays, CT scans, plus informative tables throughout, this trusted reference begins with an informative look at kinematics and the mechanisms of trauma injury. Subsequent chapters provide useful background information on the epidemiology of trauma; injury prevention; the basics of trauma systems, triage, and transport; and much more. The next section meticulously reviews generalized approaches to the trauma patient, from pre-hospital care and managing shock, to emergency department thoracotomy and the management of infections. Trauma then delivers a clear organ-by-organ survey of treatment protocols designed to help you respond to any critical care situation with confidence, no matter what body system is involved. The remaining sections of the book will help you successfully handle specific challenges in trauma—including alcohol and drug abuse, and combat-related wounds—in addition to post-traumatic complications such as multiple organ failure. FEATURES NEW! Trauma Atlas contains precise, concept-clarifying anatomical illustrations and proven surgical techniques that make common procedures more accessible than ever before High-yield section on specific approaches to the trauma patient prepares you for the wide spectrum of cases in trauma/critical surgery care, including: Disaster and mass casualty; Rural trauma;Management of shock;Post-injury hemotherapy and hemostasis;Emergency department thoracotomy; Diagnostic and interventional radiology; Surgeon-performed ultrasound;Anesthesia and pain management;Infection; A-to-Z overview of the management of specific traumatic injuries; Detailed discussion of the management of complications
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