This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-nineteenth century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of snakes belonging to this diverse, artificial family. There is a need for "one-stop shopping" offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. This book is the first synthesis of this information and includes evidence-based risk assessment, hazard rankings and specific recommendations regarding important species, many common in captivity. Fills a gap in the toxinological, medical and herpetological literature by providing a comprehensive review of this entire assemblage of snakes, with particular attention given to their capacity, real or rumored, to cause harm to humans A patient-centered, evidence-based approach is applied to analyzing documented case reports of bites inflicted by approximately 100 species. Clinical management of medically significant bites from non-front-fanged colubroids is methodically reviewed, and specific recommendations are provided
From poverty to immense wealth, from humble beginnings to international celebrity, George and Robert Stephenson's was an extraordinary joint career. Together they overshadow all other engineers, with the possible exception of Robert's friend Isambard Kingdom Brunel, for one vital reason: they were winners. For them it was not enough to follow the progress made by others. They had to be the best. Colossal in confidence, ability, energy and ambition, George Stephenson was also a man of huge rages and jealousies, determined to create his own legend. Brought up from infancy by his father, Robert was a very different person. Driven by the need to be the super-successful son his father wanted, he struggled with self-distrust and morbid depression. More than once his career and reputation teetered on the edge of disaster. But by being flawed, he emerges as a far more appealing and sympathetic figure than the conventional picture of the 'eminent engineer.' David Ross's new biography of George and Robert Stephenson sheds new light on these two giants of British engineering.
In this comprehensive final report David Ilan and 12 other contributing authors present the rich finds from the Iron Age I (circa 1200-950 BCE) levels at Tel Dan, gleaned in the course of Avraham Biran's 1966-1999 excavations at the site. The architecture, ceramics, metal, flint, bone and ground stone objects and ecofacts, all contribute to the portrayal of a cosmopolitan society that thrived, initially, under Egyptian imperial rule, subsequently forging its own way with the departure of Egyptian hegemony. The early Iron Age levels at Tel Dan show material evidence for the presence of local peoples, Egyptians, Cypriots, Aegeans, and Syrians, who together, negotiated a new identity, as Danites.
In the American imagination, the word Appalachia designates more than a geographical region. It evokes fiddle tunes, patchwork quilts, split-rail fences, and all the other artifacts that decorate a cherished romantic region of the American mind. Da
Greenfield's Neuropathology, the worlds leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis and their clinical manifestations. This account is underpinned throughout by a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. While this scientific content is of paramount importance, however, care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that also places the neuropathological findings within the context of a broader diagnostic process. The new eighth edition incorporates much new information, new illustrations and many new authors, while retaining the depth, breadth and quality of content so praised in previous editions. Each chapter opens with an introductory section designed to offer an integrated approach to diagnosis, taking account of clinical manifestations, neuroradiological and laboratory findings as well as the neuropathological and molecular genetic features of the diseases being considered. Strong emphasis has been placed on facilitating the retrieval of neuropathological information by non-neuropathologists grapping with differential diagnoses or seeking information on broad categories of neurological disease, and boxes and tables are used to present important symptoms and signs, patterns of disease and other features for ease of reference. High quality line and photographic illustrations, the majority in full colour, are all available on a companion CD, to complete the offering.
Greenfield's Neuropathology, the worlds leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis and their clinical manifestations. This account is underpinned throughout by a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. While this scientific content is of paramount importance, however, care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that also places the neuropathological findings within the context of a broader diagnostic process. The new eighth edition incorporates much new information, new illustrations and many new authors, while retaining the depth, breadth and quality of content so praised in previous editions. Each chapter opens with an introductory section designed to offer an integrated approach to diagnosis, taking account of clinical manifestations, neuroradiological and laboratory findings as well as the neuropathological and molecular genetic features of the diseases being considered. Strong emphasis has been placed on facilitating the retrieval of neuropathological information by non-neuropathologists grapping with differential diagnoses or seeking information on broad categories of neurological disease, and boxes and tables are used to present important symptoms and signs, patterns of disease and other features for ease of reference. High quality line and photographic illustrations, the majority in full colour, are all available on a companion CD, to complete the offering.
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