Human Intestinal Microflora in Health and Disease deals with human indigenous intestinal flora, the vast assemblage of microorganisms that reside in the intestinal tract. It contains information on the composition of the flora, its development, metabolic activities, importance to the host, and the consequences of upsetting its ecology. The book is organized into four parts. Part I examines the composition and development of intestinal flora. Part II deals with the metabolic activities of intestinal microflora. These include studies on carbohydrate metabolism in the human colon; the compounds used as nitrogen sources by gastrointestinal tract bacteria; and metabolic transformations of xenobiotic compounds carried out by intestinal flora. Part III examines the importance of intestinal microflora, including its role in intestinal structure and function and in suppressing the growth of pathogens. Part IV discusses the factors that can disrupt the ecology of intestinal microflora, such as antimicrobial agents, pseudomembranous colitis, and dietary and environmental stress. The research presented in this book will be of interest to both basic scientists and physicians concerned with the effects of the intestinal flora on human life.
This introduction to one of the twentieth century's most important writers examines Yeats's poems, plays and stories in relation to biographical, literary, and historical contexts. Yeats wrote with passion and eloquence about personal disappointments, his obsession with Ireland, and the modern era's loss of faith in traditional beliefs about art, religion, empire, social class, gender and sex. His works uniquely reflect the gradual transition from Victorian aestheticism to the modernism of Pound, Eliot and Joyce. This is the first introductory study to consider his work in all genres in light of the latest biographies, new editions of his letters and manuscripts, and recent accounts by feminist and postcolonial critics. While using this introduction, students will have instant access to the world of current Yeats scholarship as well as being provided with the essential facts about his life and literary career and suggestions for further reading.
Reno County was founded in 1871, and immediately settlers began arriving to break ground on a new frontier. Life here progressed as in most other Kansas counties until the discovery of salt in 1887. Three railroads competed to establish routes to bring the coal in for the manufacturing process and to ship the salt out. The growth of railroads and the central location of Reno County in Kansas created a hub of activity for the grain industry. Hutchinson became the first town founded in Reno County in 1872 when the Atchison, Topeka & Santa Fe Railroad reached the banks of the Arkansas River. Shortly after, Hutchinson became the county seat and from then on has been at the center of the dramatic changes that have come to the county. Throughout the 20th century, fortunes and empires were built on wheat and salt. Celebrating its 150th anniversary in 2021, Reno County continues to make a national impact with these two industries.
How does one culture 'read' another? In Literature and Religion, two scholars, one from China and one from the West, each read texts from the other's culture as a means of dialogue. A key issue in such an enterprise is the nature of religion and what we understand by that term in a world in which ancient religious customs seem to be dying or under threat. Does a comparative study of religious literature offer a way towards mutual understanding - or merely illustrate our differences? Underpinned by their own friendship, these two partners in conversation show what is possible.
In the world of plentiful, cheap food that so many of us in the Western World have come to accept as our birthright, it takes sensational journalism and horrific television coverage to make us realise that not all of the world's population shares this abundance. Visits to the Soviet Bloc countries, to China, most African states and various other coun tries of the Third World make one quickly realise that widespread shortage of food is just over the horizon and would be common experi ence to all were it not for the advanced technologies of Western agricul ture, food production and food manufacture. Without doubt, pesticides and other agricultural chemicals have made enormous contributions to world food production - and indeed to world peace. The introduction of many food additives, especially antioxidants, has also contributed greatly to the amount and quality of food which is available, preventing early spoilage and waste, and possibly indirectly contributing to man's health, as these antioxidants have been shown to have beneficial proper ties in the prevention of experimental malignancy and cardiovascular disease. Nevertheless, despite the enormous benefits derived from the use of agrochemicals and food additives, it is essential to remember that these are all selectively toxic chemicals, with no absolute guarantee of safety, and where the benefit to risk ratio is always a compromise adjusted by the expediency of political and financial aspects of food production.
This issue will focus on the global state of hematology and will include articles such as: The Global Burden of Anemia, Iron Deficiency Anemia: Problems in Diagnosis and Therapy, Progress Towards the Control and Management of the Thalassemias, Problems and Approaches for Blood Transfusion in the Developing Countries, and many more!
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivity and resolution have facilitated the analysis of cross-linked products. Updated to reflect the advances of the 21st century, this book offers: An overview of the chemical principles underlying the processes of cross-linking and conjugation A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations
First published in 1994. This fully revised and updated edition of the bestselling Textual Scholarship covers all aspects of textual theory and scholarly editing for students and scholars. As the definitive introduction to the skills of textual scholarship, the new edition addresses the revolutionary shift from print to digital textuality and subsequent dramatic changes in the emphasis and direction of textual enquiry.
This pioneering book introduces students to the practice and art of creative writing and creative reading. It offers a fresh, distinctive and beautifully written synthesis of the discipline. David Morley discusses where creative writing comes from, the various forms and camouflages it has taken, and why we teach and learn the arts of fiction, poetry and creative nonfiction. He looks at creative writing in performance; as public art, as visual art, as e-literature and as an act of community. As a leading poet, critic and award-winning teacher of the subject, Morley finds new engagements for creative writing in the creative academy and within science. Accessible, entertaining and groundbreaking, The Cambridge Introduction to Creative Writing is not only a useful textbook for students and teachers of writing, but also an inspiring read in its own right. Aspiring authors and teachers of writing will find much to discover and enjoy.
Recent critical studies of late modernism have explored the changing sense of both history and artistic possibility that emerged in the years surrounding World War II. However, relatively little attention has been devoted to the impact of poets' theological deliberations on their visions of history and their poetic strategies. Divine Cartographies: God, History, and Poiesis in W. B. Yeats, David Jones, and T. S. Eliot triangulates key texts as attempts to map theologically driven visions of the relation between history and eternity. W. David Soud considers several poems of Yeats's final and most fruitful engagement with Indic traditions, Jones's The Anathemata, and Eliot's Four Quartets. For these three poets, working at the height of their powers, that project was inseparable from reflection on the relation between the individual self and God; it was also bound up with questions of theodicy, subjectivity, and the task of the poet in the midst of historical trauma. Drawing on the fields of Indology, theology, and history of religions as well as literary criticism, Soud explores in depth and detail how, in these texts, theology is poetics.
Emergency management university programs have experienced dramatic and exponential growth over the last twelve years. This new, fully updated edition introduces majors and minors to the field and provides content accessible to those students taking introductory emergency management courses. The book’s student-centered focus looks at the regional, state, and local level response, as well as some of the often misunderstood or overlooked social aspects of disasters. Real-world cases are described throughout including considerations of international emergency management and disasters alongside features from former students now working as professionals in the field of emergency management.
Since the attacks of 9/11, billions of dollars and countless resources have been committed and expended in the attempt to make the nation more secure. Introduction to Homeland Security: Second Edition is written by a team of homeland security and justice professionals on the cutting edge of the field. The text is a comprehensive examination of current and future challenges and explores how the United States has chosen to confront these threats with both its military and civilian agencies. Topics include: A history of homeland security in the United States The mission of the various agencies in the Department of Homeland Security and Department of Defense The foundations of emergency management: mitigation/prevention, preparedness, response, and recovery Inter-agency planning and cooperation and private partnership A survey of the most significant natural disasters and accidents, explored through case studies International and domestic terrorism and threat groups The impact of transportation and border security issues and the violence occurring in the Southwest Globalization and the role of intelligence in homeland security Future challenges in the field of homeland security Each chapter begins with objectives and ends with a summary, key terms, and discussion questions. Ample references encourage further study and research. The book is a premier text for criminal justice, homeland security, national security, and intelligence programs in universities and an ideal reference for professionals as well as policy and research institutes.
Events such as the 2004 Indian Ocean Tsunami, Hurricane Katrina in 2005 and the Japanese earthquakes and tsunamis in 2011 have provided unfortunate reminders of the susceptibility of many communities to devastating losses from natural hazards. These events provided graphic illustrations of how extreme hazard events adversely impact on people, affect communities and disrupt the community and societal mechanisms that serve to organize and sustain community capacities and functions. However, there is much that communities can do to mitigate their risk and manage disaster consequences. The construct that epitomizes how this is done is resilience. The contents of this volume provide valuable insights into how societal resilience can be developed and sustained. This considerably expanded new edition presents major topics of: Coexisting with Natural Hazards; Urban Resilience in Asia; Lifelines and Urban Resilience; Business Continuity in Disaster; Hazard Mitigation in Communities; Hazard Readiness and Resilience; Child Citizenship in Disaster Risk; Old Age and Resilience; Gender and Disaster Resilience; Impact of High Functionality on Resilience; Art and Resilience; Cross-Cultural Perspectives and Coping with Hazards; Religious Practices and Resilience; Living in Harmony with our Environment; Critical Incidence Response; Governance; Heat Wave Resilience; Wildfire Disaster Resilience; and Progress and Challenges to Disaster Risk Reduction and Resilience. This exceptional book brings together contributions from international experts in core areas and includes chapters that provide and overarching framework within which the need for interrelationships between levels to be developed is discussed. The book will be an outstanding resource for those researching or teaching courses in emergency management, disaster management, community development, environmental planning and urban development. In addition, it will serve law enforcement and emergency agencies, welfare agencies, and professionals in applied psychology.
Only 15 years ago a conference on dietary fiber, let alone an international conference, would have been considered an extremely unlikely, and in fact an unthinkable, event. Yet in recent years a number of such conferences have taken place at the international level and in different parts of the world; the conference of which the present volume is an outgrowth is the second to have been held in Washington, D. C. This extraordinary development of interest in a hitherto largely neglected component of diet has been reflected by a veritable explosion of scientific literature, with published articles increasing 40-fold, from around ten to over 400 per year, within the decade 1968-1978. Not only has the growth of interest in and knowledge of fiber made it perhaps the most rapidly developing aspect of nutritional science in recent history if not in all time, but epidemiologic studies relating fiber intake to disease patterns, subsequently broadened to include other food components, have been largely responsible for the current concept of diseases characteristic of modern Western culture and lifestyle. The potential importance of this realization is forcefully underlined by the considered judgment of Thomas MacKeown, epidemiologist and medical historian of Birmingham University, England.
A compelling account of Protestant loss of power and self-confidence in Ireland since 1795, illustrating how 'descendancy' was experienced and perceived.
Since the attacks of 9/11, billions of dollars and countless resources have been committed and expended in the attempt to make the nation more secure. Introduction to Homeland Security: Second Edition is written by a team of homeland security and justice professionals on the cutting edge of the field. The text is a comprehensive examination of curr
Oral Colon-Specific Drug Delivery covers approaches used to deliver a variety of drugs to the colon. Anatomy and physiology of the gastrointestinal tract as it affects colonic drug delivery and pharmacokinetics are reviewed, as well as drug absorption from the colon. The book presents valuable information on a variety of topics, including oral peptide/protein delivery, dextran-based delivery systems, glycoside/glycosidase-based delivery, azo-bond prodrugs, hydroxypropyl methacrylamide copolymers for colonic delivery, and matrices for colonic drug delivery. Special emphasis is placed on delivery systems, especially biochemical approaches to delivery, such as the use of degradable polymers and both low and high molecular weight prodrugs. Oral Colon-Specific Drug Delivery will provide a valuable reference resource for gastroenterologists, pharmaceutical scientists, and other researchers working with drug delivery to the colon.
This is basically an account of Davids combat experience with the US Marine Corps infantry in Vietnam. Through the years, David often spoke of these experiences, only to hear others tell his stories with various discrepancies. David wrote this book to help others keep the details accurate. The war experience is bracketed by information of his life before and after Vietnam.
The story of one Mennonite family that chose to leave the Soviet Union when others were choosing to remain, not realizing this was the last opportunity. They left everything familiar and dear, for an unknown future in a land where they knew no one. They had a deep trust in God and after a long and prosperous life in Canada, they were quick to acknowedge God's faithfulness throughout their life's journey. Also contains a Loewen genealogy, 1735 - 2015.
Most scientists and many of the world's farmers have abandoned traditional farming practices and systems in an effort to increase production and to improve the efficiency of land and labor use. The resulting "modern" systems largely ignore many of the sustainable pest management practices that have evolved among farmers over centuries. In this book
Malpractice settlements are large for undetected hydroxychloroquine and chloroquine toxicity which, if untreated, can lead to permanent loss of central vision. Knowledge of the ocular toxicity of these drugs has increased during the past fifty years as their use has expanded. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why the drugs are prescribed and dosing considerations. Additionally, the book addresses practice management considerations, including coding, reimbursement and equipment costs, and the medico-legal responsibilities of the rheumatologist and of the ophthalmologist. Guidelines for the management of hydroxychloroquine and chloroquine vary around the world and differences between the guidelines of the United Kingdom, the United States, and other countries are identified. The book concludes with a collection of case examples illustrating common clinical scenarios and their management. This book is a “must-have” resource for physicians who use these drugs.
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
The most comprehensive and authoritative reference available today on colorectal surgery This revised fourth edition of Gordon and Nivatvongs' Principles and Practice of Surgery for the Colon, Rectum, and Anus edited by David Beck, Steven Wexner, and Janice Rafferty strikes a perfect balance between evidence-based medicine, in-depth details, and clinical pearls. The result is a highly engaging and authoritative tome in the grand tradition of Philip Gordon and Santhat Nivatvongs. Building on the widely acclaimed previous editions' reputation for superb quality and reader-friendliness, the fourth edition includes contributions from an expanded cadre of internationally known experts. Significant advances have been made in this field since the third edition was published. The latest diagnostic modalities are highlighted such as MRI, CT angiography, and enterography. The first section covers essentials such as anatomy, physiology, diagnosis, colonoscopy, and patient management. Sections two through four discuss a full spectrum of anorectal diseases, colorectal disorders, trauma, unexpected challenges, and complications. Among the additions are expanded sections on transanal total mesorectal excision, genetics, personalized medicine, "wait and watch" principles, outpatient management of anorectal surgery, and large bowel obstruction. Key Highlights Thirty-seven chapters cover a wide array of gastrointestinal disorders such as fecal incontinence, ulcerative colitis, Crohn's disease, diverticulitis, carcinomas, and other malignant lesions A multidisciplinary team approach to rectal cancer encompasses rectal cancer protocol MRI, synoptic reporting, and various neoadjuvant therapy protocols The use of cutting-edge approaches including laparoscopy, robotics, hyperbaric oxygen, and radiofrequency tissue remodeling Superb full-color plates, illustrations, photographs, diagrams, detailed tables, graphics, and surgical videos elucidate underlying disease and management As the most comprehensive resource on colorectal surgery available on the market today, this is a must-have for every colon and rectal surgeon – from residents to veteran practitioners.
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