Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.
The Child Psychotherapy Treatment Planner, Fourth Edition provides treatment planning guidelines and an array of pre-written treatment plan components for behavioral and psychological problems, including blended family problems, children of divorce, ADHD, attachment disorder, academic problems, and speech and language disorders. Clinicians with adult clients will find this up-to-date revision an invaluable resource.
The Adolescent Psychotherapy Treatment Planner, Fourth Ediiton provides treatment planning guidelines and an array of pre-written treatment plan components for behavioral and psychological problems, including anger management, blended family conflicts, low self-esteem, chemical dependence, eating disorders, and sexual acting out. Clinicians with adolescent clients will find this up-to-date revision an invaluable resource.
Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.
Herodotus, one of the earliest and greatest of Western prose authors, set out in the late fifth century BC to describe the world as he knew it. This commentary by leading scholars, originally published in Italian, has been fully revised by the original authors and is now presented for English readers.
Drawing on a wide and rich array of sources, this book explores the nature and extent of Dutch trade and commerce in the Río de la Plata during three decades of the least-studied century (1650–1750) of Spain's rule in the Americas. In doing so, it raises important questions about trade in colonial South America and how it was impacted by the Dutch, suggesting that these transactions were carried out within the confines of the law, contradicting common beliefs among scholars that this trading was not regulated. The book contributes to a growing literature on contraband trade, administration, networks, and corruption while challenging narratives of exclusively Spanish influence on the Americas.
Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.
Almost from professional baseball's birth more than 130 years ago, the batting championship has been one of the sport's most highly coveted awards. Since 1949, the Louisville Slugger company has presented the man with the highest batting average at season's end with the Silver Bat Award, a regulation-sized metal bat plated in sterling silver with the winner's name and average engraved upon it. Throughout the years, heated battles for the Silver Bat Award have featured unusual machinations by players, managers, and entire teams, including allegations of cheating, bribery, deliberate misplays, and questionable strategies, and, in one especially bitter campaign, charges of racism. Here are the stories behind these races.
Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
This is a straightforward history of the Athletics franchise, from its Connie Mack years in Philadelphia with teams featuring Eddie Collins, Chief Bender, Jimmy Foxx, Mickey Cochrane and Lefty Grove, through its 13 years in Kansas City, under Arnold Johnson and Charles O. Finley, and on to its great years in Oakland--with the three World Series wins featuring Catfish Hunter, Reggie Jackson, Sal Bando and Vida Blue, and the conflicts with Finley--as well as the less successful seasons that followed, then the Series sweep in 1989, and ending up with the unusual operation of the club by Billy Beane.
What is known of the expansion of the Roman Empire in Asia and adjacent lands to the East between 133 B.C. and A.D. 285 is presented here in a comprehensive organization of all the existing scholarship. An authority in the field of ancient history and archaeology, Mr. Magie presents a thorough account of political and economic conditions in this period. Volume 2 contains the notes. Originally published in 1950. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
The book summarizes the important developments in blood banking and transfusion medicine made from the end of World War II in 1946 through to the impact of the pandemic in 2021. Some of the important topics covered include the development of component therapy, improvements in blood preservation, evolving clinical uses of blood components, policy debates, the impact of the emergence of HIV infection and blood safety, the rising influence of more “corporate” business models, and COVID-19 effects. The book surveys important developments over these 75 years, through four very different but intertwined lenses: the evolving science, the resulting evolution in medical practice, how the social environment and the blood banking field affected one another, and the political and public policy issues that arose. It is the social dimension in particular that distinguishes this work from other writings. Practitioners, scientists and scholars in transfusion medicine and blood banking will find the book useful, as will others in related fields such as oncology, emergency medicine, public health, and health care public policy.
Professor Whitehead has provided a new translation of the five surviving forensic speeches of the Athenian lawyer-politician Hypereides (390/89-322 BC). Hypereides' importance lies not only in his speeches, but also in his centrality in the political life of ancient Athens, as a contemporary of Demosthenes, and one of the canonical Ten Attic Orators. This book, which includes a general introduction and lavish historical and literary commentary, represents the first complete collection of Hypereides' works in any language.
Chemical and Molecular Basis of Nerve Activity contains 16 chapters that discuss the significant advances in the study of the molecular events underlying bioelectricity and nerve excitability. After briefly describing the physiology and mechanisms of the nervous system, this book goes on examining the physiologically significant features and nerve activity roles of acetylcholines and acetylcholinesterase. A chapter highlights the mechanism of acetylcholinerase inhibition by nerve gases and insecticides. Other chapters explore the characteristic properties of choline acetylase enzyme; the relationships between chemical forces and electrical activity; and the effect of acetylcholine and analog compounds on the isolation of receptor protein and on synaptic junctions. The remaining chapters deal with the essential role of acetylcholine in the generation of bioelectric current and the differences between axonal conduction and synaptic transmission. The supplementary texts look into the progress in the biochemistry of excitability and present an integral model of nerve excitability. This book will be of great benefit to biologists and neurologists.
A major scholarly and readable history of women in broadcast news, covering the broadcast journalistic roles of women from the 1920s through the mid-1980s. Authors Hosley and Yamada, both with extensive professional experience in broadcasting and broadcast news as well as serving on the faculty of Stanford University's Mass Media Institute, have produced a heavily researched and well-written book, which gives attention not only to the more familiar names but also to the many women whose pioneer work in broadcast journalism had led to gradual acceptance of women in what had been considerd a male field. Choice There are a lot of names in this book. Some are immediately recognizable . . . other names are virtually unknown, making this book a valuable reference text for students interested in researching the careers of women broadcasters who have been all but forgotten. The authors, both of whom have extensive backgrounds in broadcasting, have done a commendable job of identifying women who have pioneered in electronic journalism. . . Indeed, this book is so engrossing one only wishes that it were longer. The authors touch on complex issues--such as the impact of the Civil Rights Act of 1964 and the FCC's decision to mandate affirmative action programs to remedy past discrimination--that call for more complete treatment in future works. Yet this book is an excellent starting point for serious study of women and broadcast news. It is highly recommended for courses in communications history and broadcasting and women's studies. Journalism Quarterly This is the first book to tell the story of women in broadcast news. It presents a historical overview of how the evolution of women in news has contributed to, and reflected, changes in our society. It identifies the newswomen who were pioneers in radio and television's developing years and focuses on those whose careers have had the greatest influence on American society through their impact on radio and television. Included are profiles of the major trail-blazers in the industry, such as Sigrid Schultz, the first female radio foreign correspondent; Helen Sioussat, the first woman network news executive; Dorothy Fuldheim, the first woman to anchor a news program; and network correspondent Pauline Frederick, the dean of women electronic journalists.
The objective of this report is to summarize U.S. Department of Energy (DOE) supported studies in the Dixie Valley geothermal area and to relate the results of those studies to other, non-DOE-supported studies that have been done in the valley during the past 40 to 50 years. This compilation of past research includes new analysis resulting in a more in-depth understanding of the geothermal system in Dixie Valley. The focus is on the basin geology and structure, thermal regime, and geothermal system geochemistry. Reservoir studies are briefly discussed.
Now in vibrant full color throughout, Rogers’ Textbook of Pediatric Intensive Care, 5th Edition, continues its tradition of excellence as the gold standard in the field. For more than 25 years, readers have turned to this comprehensive resource for clear explanations of both the principles underlying pediatric critical care disease and trauma as well as how these principles are applied in clinical practice. In the 5th Edition, more than 250 global contributors bring you completely up to date on today’s understanding, treatments, technologies, and outcomes regarding critical illness in children.
Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process. This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority, cluster and stepped wedge trials. Other new chapters describe data and safety monitoring, biomarker studies, and feasibility studies. Updated and expanded sections discuss situations where multiple organs, different body locations or competing risks are involved, subgroup analysis, and multiple outcomes. Written by an author team with extensive experience in conducting clinical trials, this book: Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced Features several new chapters, updated case studies and examples, and references to changes in regulations Explains basic randomised trials, including the parallel two-group controlled trial with a single outcome measure Covers paired trial designs and trials with more than two interventions Includes a chapter on miscellaneous topics such as adaptive designs, large simple trials, Bayesian methods for very small trials, alpha-spending functions and the predictive probability test Randomised Clinical Trials is essential reading for clinicians, nurses, data managers, and medical statisticians involved in clinical trials, and for health practitioners responsible for direct patient care in a clinical trial setting.
Mollison's Blood Transfusion in Clinical Medicine is an icon in the field of transfusion and the first edition was published in 1951. The book arose from the concept of the transfusionist, as both scientist and expert consultant. For many years, this text has provided the primary, and often the sole, reference for detailed information and practical experience in blood transfusion. The book is completely revised and updated throughout to include the latest advances and developments in the field.
Over the past 30 years high-resolution CT (HRCT) has matured to become an integral part of the multidisciplinary evaluation in diffuse lung disease. In this regard, Webb, Muller and Naidich’s High-Resolution CT of the Lung, 6th Edition, is a ‘gold standard’ reference that aims to keep radiologists and pulmonologists alike at the cutting edge of the ever-evolving field of thoracic imaging. The new US-European author team continues the tradition of excellence which readers have come to expect while the underlying layout and ethos — established by the ‘founding’ author team — remain. The new edition aims to brings readers up to date not only with recent advances but also with the important conceptual changes in thinking in various fields of thoracic imaging. Also featured in this updated edition is authoritative guidance on HRCT findings and differential diagnosis, as well as the characteristics of the common lung diseases assessed using HRCT, all enhanced by a multitude of new images and updated content throughout.
Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. David J. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin’s lymphoma, and more. Additional features such as tables discussing antibody specifications, differential diagnosis boxes, ancillary anatomic molecular diagnostics, and full-color histological images ensure user-friendly coverage that makes key information easy to find and apply. This concise and complete resource is today’s indispensable guide to the effective use of immunohistochemical diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Presents chapters arranged by organ system for comprehensive coverage of all relevant information in a convenient and intuitive organization. Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors. Includes Key Diagnostic Points boxes in every chapter for a quick summary of text areas that are of particular importance. Features an expert author for each chapter to ensure coverage of the current state of the art. Provides guidance on the role of genomics in identifying genetic and molecular aspects of disease that may affect patient care and therapeutic approaches. Covers theranostic applications to enable you to evaluate therapeutic choices based on immunohistochemical results. Reflects the latest developments in the field through new chapters on molecular anatomic pathology and immunocytology, as well as updated chapters on immunohistology of the prostate, bladder, testis, and kidney and Non-Hodgkin’s lymphoma. Discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Presents key differential diagnoses boxes that provide tabular summaries of DDx and algorithms. Features discussions of ancillary anatomic molecular diagnostics as an adjunct to immunohistochemistry for a more well-rounded diagnostic approach.
It's been more than a century since Connecticut had big league baseball, but in the 1870s, Middletown, Hartford, and New Haven fielded professional teams that competed at the highest level. By the end of the decade, when the state's final big league team, Mark Twain's beloved Hartford Dark Blues, left the National League, baseball's transition from amateur pastime to major league sport had been accomplished. And Connecticut had played a significant role in its development. The history of the Nutmeg State's three major league teams is described here in full, and the author thoughtfully examines their influence within the regional baseball scene.
A Comparative History of Commerce and Industry, Volume II offers a subjective review of how the cultural, social and economic institutions of commerce and industry evolved in industrialized nations to produce the institution we now know as business enterprise.
Pesticide Formulation and Adjuvant Technology brings together experts from industry, academia, regulatory offices, and the legal profession to provide a complete and international reference on agrichemical formulations and modern adjuvant technology. Global specialists discuss key topics, from scientific and technical issues to regulatory and legal aspects, including:
Taking a practical, goal-oriented approach to teaching sales management skills and concepts, this text uses the steps along the typical career path of the sales manager, from field representative to upper management.
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