This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
David Herrmann's work is the most complete study to date of how land-based military power influenced international affairs during the series of diplomatic crises that led up to the First World War. Instead of emphasizing the naval arms race, which has been extensively studied before, Herrmann draws on documentary research in military and state archives in Germany, France, Austria, England, and Italy to show the previously unexplored effects of changes in the strength of the European armies during this period. Herrmann's work provides not only a contribution to debates about the causes of the war but also an account of how the European armies adopted the new weaponry of the twentieth century in the decade before 1914, including quick-firing artillery, machine guns, motor transport, and aircraft. In a narrative account that runs from the beginning of a series of international crises in 1904 until the outbreak of the war, Herrmann points to changes in the balance of military power to explain why the war began in 1914, instead of at some other time. Russia was incapable of waging a European war in the aftermath of its defeat at the hands of Japan in 1904-5, but in 1912, when Russia appeared to be regaining its capacity to fight, an unprecedented land-armaments race began. Consequently, when the July crisis of 1914 developed, the atmosphere of military competition made war a far more likely outcome than it would have been a decade earlier.
Winner of the BMA 2011 book awards: psychiatry category Winner of the Australian Journal of Ageing book of the year award This definitive work on dementia and related disorders has been fully updated and revised to reflect recent advances in this fast-moving field. The incidence of dementia continues to rise as the population of the world ages, and the condition represents one of the most significant challenges facing societies and health professionals in the next half-century. In this, the most comprehensive single volume work available on the subject, the editors have met this challenge by assembling a team of the world's leading experts on all aspects of the condition, from history, epidemiology and social aspects to the latest neurobiological research and advanced therapeutic strategies.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background* Contains twice the number of chapters of the first edition* Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
David Herrmann's work is the most complete study to date of how land-based military power influenced international affairs during the series of diplomatic crises that led up to the First World War. Instead of emphasizing the naval arms race, which has been extensively studied before, Herrmann draws on documentary research in military and state archives in Germany, France, Austria, England, and Italy to show the previously unexplored effects of changes in the strength of the European armies during this period. Herrmann's work provides not only a contribution to debates about the causes of the war but also an account of how the European armies adopted the new weaponry of the twentieth century in the decade before 1914, including quick-firing artillery, machine guns, motor transport, and aircraft. In a narrative account that runs from the beginning of a series of international crises in 1904 until the outbreak of the war, Herrmann points to changes in the balance of military power to explain why the war began in 1914, instead of at some other time. Russia was incapable of waging a European war in the aftermath of its defeat at the hands of Japan in 1904-5, but in 1912, when Russia appeared to be regaining its capacity to fight, an unprecedented land-armaments race began. Consequently, when the July crisis of 1914 developed, the atmosphere of military competition made war a far more likely outcome than it would have been a decade earlier.
The rising prevalence of dementia in the population continues to pose a serious public health challenge in both the developed and the developing world. Previous editions of Dementia have become acknowledged as a key 'gold standard' work in this field, and have had a genuinely international approach. The third edition has been fully revised and upda
In Origins of Agriculture in Western Central Asia, archaeologist David R. Harris addresses questions of when, how, and why agriculture and settled village life began east of the Caspian Sea. The book describes and assesses evidence from archaeological investigations in Turkmenistan and adjacent parts of Iran, Uzbekistan, and Afghanistan in relation to present and past environmental conditions and genetic and archaeological data on the ancestry of the crops and domestic animals of the Neolithic period. It includes accounts of previous research on the prehistoric archaeology of the region and reports the results of a recent environmental-archaeological project undertaken by British, Russian, and Turkmen archaeologists in Turkmenistan, principally at the early Neolithic site of Jeitun (Djeitun) on the southern edge of the Karakum desert. This project has demonstrated unequivocally that agropastoralists who cultivated barley and wheat, raised goats and sheep, hunted wild animals, made stone tools and pottery, and lived in small mudbrick settlements were present in southern Turkmenistan by 7,000 years ago (c. 6,000 BCE calibrated), where they came into contact with hunter-gatherers of the "Keltiminar Culture." It is possible that barley and goats were domesticated locally, but the available archaeological and genetic evidence leads to the conclusion that all or most of the elements of the Neolithic "Jeitun Culture" spread to the region from farther west by a process of demic or cultural diffusion that broadly parallels the spread of Neolithic agropastoralism from southwest Asia into Europe. By synthesizing for the first time what is currently known about the origins of agriculture in a large part of Central Asia, between the more fully investigated regions of southwest Asia and China, this book makes a unique contribution to the worldwide literature on transitions from hunting and gathering to agriculture.
This book covers the latest advances in non-muscle invasive bladder cancer care. It provides a review of the available evidence base for the efficacy of a range of therapeutic techniques, diagnostic procedures and risk factors. Management of Non-Muscle Invasive Bladder Cancer features detailed guidance in uniformly formatted chapters on how to properly apply a range of available therapeutic treatments relevant for patient care. It is a valuable resource for all trainee and practising medical professionals who treat these patients.
The iconic minaret of Jām stands in a remote mountain valley in central Afghanistan, the finest surviving monument of the enigmatic 12th-century Ghūrid dynasty. The re-discovery of the minaret half a century ago prompted renewed interest in the Ghūrids, and this has intensified since their summer capital at Jām became Afghanistan’s first World Heritage site in 2002. Two seasons of archaeological fieldwork at Jām, the detailed analysis of satellite images and the innovative use of Google Earth as a cultural heritage management tool have resulted in a wealth of new information about known Ghūrid sites, and the identification of hundreds of previously undocumented archaeological sites across Afghanistan. Drawing inspiration from the Annales School and the concept of an ‘archipelagic landscape’, Thomas has used these data to re-assess the Ghūrids and generate a more nuanced understanding of this significant Early Islamic polity. In addition to complementing the événements which form the focus of the urban-based historical sources, the new archaeological data are used by Thomas to reconsider the urban characteristics of the Ghūrids’ summer capital. Throughout The Ebb and Flow of the Ghūrid Empire, Thomas uses this to explore the issues of Ghūrid identity, ideology and the sustainability of their polity.
For one-semester, advanced undergraduate/graduate courses in Biotransport Engineering. Presenting engineering fundamentals and biological applications in a unified way, this text provides students with the skills necessary to develop and critically analyze models of biological transport and reaction processes. It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.
In the past, the prototypes for characterizing drug use were heroin and cocaine, so that research has focused on possible commonalities between any substance and these drugs. Addiction controversies explores the problems of the commonalities approach by looking at dissimilarities as well. The first chapters of Addiction Controversies trace the development of modern medical attitudes to drug use and the current controversy over its decriminalization. The second set of chapters examines the extent to which drugs have common biological and sociological mechanisms of action and contrasts these explanations. The final chapters consider the extent to which the desires for different substances are the same and the biological and social explanations of relapse. Clinicians, researchers and students in all areas of substance use will be stimulated by these challenges to current thinking and will enjoy the comparative approach that is taken by the contributors to Addiction Controversies.
In-depth study of internet-enhanced healthcare services Complete and thorough survey of the most promising e-health technologies Presents numerous real world examples Emphasis on international health-informatics topics, such as better access of states / countries to modern e-health technologies developed by leading centers
A comprehensive clinical reference on managing the entire spectrum of movement disorders NEW DVD with video clips Featuring contributions from more than one hundred leading experts, this full-color text covers pathophysiology, diagnosis, and management of all movement disorders - from ataxia to Parkinson's Disease. Movement Disorders examines the neurobehavioral changes and comorbidities that frequently occur and incorporates the latest genetic information and the most current references. Chapters cover Clinical Presentation and Course, Pathophysiology, Differential Diagnosis, Etiologies, and Treatment. The third edition is highlighted by a new full-color presentation, more than 240 color illustrations and photos, and a DVD with video clips of patients with movement disorders.
The Islamic world drew upon a myriad of pre-existing styles of fortification, taking Romano-Byzantine, Indian and Chinese ideas to create a highly effective and sophisticated hybrid fortification that was both new and distinctive. This book examines early Saracen fortifications, covering their historical background, socio-political circumstances, and their role in protecting industry, trade and the frontiers of the Islamic world. From the mayyad 'castles in the desert' of Jordan and Syria to the 'Round City of Baghdad' and the great gates of Cairo, this book provides an insight into the majesty of the Saracen forts, illustrated with specially commissioned artwork and cutaways, together with photographs of period engravings and images of the sites today.
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