Some think that liturgy is formal, public, and for ordinary people, while mysticism is uncontrollable, private, and for extraordinary saints. Is there a connection between the two? In this volume, David Fagerberg proposes that mysticism is the normal crowning of the Christian life, and the Christian life is liturgical. We intuitively sense that liturgy and theology and mysticism have an affinity. Liturgical theology should reveal liturgy’s mystical heart. Liturgical theology asks “What happens in liturgy?” and liturgical mysticism asks “What happens to us in liturgy?”, and perfects our interior liturgy. In Liturgical Mysticism, Fagerberg directs the reader to look fixedly at Christ, who is the Mystery present in liturgy, and who bestows his resurrection power upon his adopted children. “In a time where both too wild and too mild spiritualities abound, it is audacious to put forward a book on liturgical mysticism. [This book] continues to enrich liturgical theology by amplifying its horizon and solidifying the foundation on which it rests.” Joris Geldhof Katholieke Universiteit Leuven
In the new global economy, more countries have opened up to international competition and rapid capital flows. However, in the triad the process of globalization is rather asymmetric. With a rising role of multinational companies there are favorable prospects for higher global growth and economic catching-up, respectively. Theoretical analysis suggests key ingredients of sustained growth, but there is also a new concept of a long-term equilibrium income gap in which convergence is rather unlikely. The analysis also picks up European and US labor market issues in the context of economic globalization and raises the question of which EU policies in the field of labor market reform and of innovation policies are adequate.
This book gathers fourteen Catholic scholars to present, examine, and explain the often misunderstood process of "deification". The fifteen chapters show what "becoming God" meant for the early Church, for St. Thomas Aquinas and the greatest Dominicans, and for St. Francis and the early Franciscans. This book explains how this understanding of salvation played out during the Protestant Reformation and the Council of Trent. It explores the thought of the French School of Spirituality, various Thomists, John Henry Newman, John Paul II, and the Vatican Councils, and it shows where such thinking can be found today in the Catechism of the Catholic Church. No other book has gathered such an array of scholars or provided such a deep study into how humanity's divinized life in Christ has received many rich and various perspectives over the past two thousand years. This book seeks to bring readers into the central mystery of Christianity by allowing the Church's greatest thinkers and texts to speak for themselves, demonstrating how becoming Christ-like and the Body of Christ on earth, is the only ultimate purpose of the Christian faith.
The Stockholm Conference of 1972 drew the world’s attention to the global environmental crisis, but for people in Sweden the threat was nothing new. Anyone who read the papers or watched the television news was already familiar with the issues. Five years early, in the summer of 1967, the situation was very different. So what happened in between? This book explores the ‘environmental turn’ that took place in Sweden in the late-1960s. This radical change, the realisation that human beings were in the process of destroying their own environment, had major and far-reaching consequences. What was it that opened people’s eyes to the crisis? When did it happen? Who set the ball rolling? These are some of the questions the book addresses, shedding new light on the history of environmentalism.
Dramatic and controversial changes in the funding of science over the past two decades, towards its increasing commercialization, have stimulated a huge literature trying to set out an "economics of science". Whether broadly in favour or against these changes, the vast majority of these frameworks employ ahistorical analyses that cannot conceptualise, let alone address, the questions of "why have these changes occurred?" and "why now?" Nor, therefore, can they offer much insight into the crucial question of future trends. Given the growing importance of science and innovation in an age of both a globalizing knowledge-based economy (itself in crisis) and enormous challenges that demand scientific and technological responses, these are significant gaps in our understanding of important contemporary social processes. This book argues that the fundamental underlying problem in all cases is the ontological shallowness of these theories, which can only be remedied by attention to ontological presuppositions. Conversely, a critical realist approach affords the integration of a realist political economy into the analysis of the economics of science that does afford explicit attention to these crucial questions; a ‘cultural political economy of research and innovation’ (CPERI). Accordingly, the book sets out an introduction to the existing literature on the economics of science together with novel discussion of the field from a critical realist perspective. In arguing thus across levels of abstraction, however, the book also explores how concerted engagement with substantive social enquiry and theoretical debate develops and strengthens critical realism as a philosophical project, rather than simply ‘applying’ it. While the first of these two volumes argues how mainstream economics is inadequate to the task of an explanatory and critical ‘economics of science’, the challenge in this second volume is to examine the strengths and weaknesses of disciplines offering more promising starting points. Two social scientific disciplines are particularly promising candidates, starting from ‘economy’ or ‘science’, namely heterodox political economy and science & technology studies respectively. Synthesising these into an ‘economics of science’, however, still encounters considerable hurdles, in that there remain some fundamental and mutual philosophical incompatibilities. Formulating an ‘economics of science’ thus demands that both ‘economics’ and ‘science’ be redefined. The book explores how a critical realist approach affords some common ground upon which this productive synthesis may be pursued, in the form of a cultural political economy of research and innovation (CPERI).
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, and gene expression profiles of normal and diseased tissues are being rapidly generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industrial practitioners at the 5th Asia-Pacific Bioinformatics Conference held in Hong Kong in January 2007.
This book analyzes the role of institutions in conditioning entrepreneurship and innovation to achieve economic development. Set against the backdrop of populism, this book is based on the premise that formal and informal institutional factors and entrepreneurship are closely linked and that studying the economic development of both developed and emerging economies can help us disentangle the role of entrepreneurship and innovation in developing countries. Using institutional economics as a main theoretical framework and the sociotechnical subsystems as a complementary approach, the authors present a detailed literature review to demonstrate that it is possible to identify the true role of entrepreneurship and innovation in the economic development process. The book embraces complexity to better measure and comprehend economic development, bringing a more compelling perspective on the importance of entrepreneurship and innovation for different dimensions of development. A valuable resource for students, scholars, and policymakers, the authors offer clear recommendations for developing countries.
Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research. Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.
Sources of Knowledge and Entrepreneurial Behavior delves into the nature and importance of the relationship between sources of knowledge and entrepreneurial behavior, and should be of interest to both academics and policy-makers. David B. Audretsch and Albert N. Link use the Knowledge Spillover Theory of Entrepreneurship as the conceptual foundation for why individuals decide to become entrepreneurs. Then, using a database of more than 4,000 small and relatively new European companies from 10 different countries, called the AEGIS database, Audretsch and Link offer new insights about the relationship between knowledge sources and entrepreneurial behavior. In their analysis of the empirical evidence in support of the Knowledge Spillover Theory of Entrepreneurship, Audretsch and Link conclude that there is no singular source of knowledge driving entrepreneurship, but a plethora of knowledge sources, each associated with different dimensions of entrepreneurial activity. The intellectual breakthrough in this book is not that knowledge matters or that it especially matters for entrepreneurship. Rather, Audretsch and Link show that knowledge, and especially entrepreneurial knowledge, is not a homogeneous phenomenon. There are multiple sources of knowledge that act on entrepreneurial performance in a myriad of ways.
Provides a systematic overview, analysis, framework, research agenda, and strategic directions for the study of public sector innovation. The authors discuss: how public organizations and public sector employees can innovate, barriers and impediments, governments' role for innovation, sources of innovation, types of innovation, ethics.
Despite decades of effort and billions of dollars spent, two thirds of people in sub-Saharan Africa still lack access to electricity, a vital pre-cursor to economic development and poverty reduction. Ambitious international policy commitments seek to address this, but scholarship has failed to keep pace with policy ambitions, lacking both the empirical basis and the theoretical perspective to inform such transformative policy aims. Sustainable Energy for All aims to fill this gap. Through detailed historical analysis of the Kenyan solar PV market the book demonstrates the value of a new theoretical perspective based on Socio-Technical Innovation System Building. Importantly, the book goes beyond a purely academic critique to detail exactly how a Socio-Technical Innovation System Building approach might be operationalized in practice, facilitating both a detailed plan for future comparative research as well as a clear agenda for policy and practice. Chapter 1 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138656925_oachapter01.pdf Chapter 6 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138656925_oachapter06.pdf
In this book, the authors set forth a new model of globalization that lays claims to supersede existing models, and then use this model to assess the way the processes of globalization have operated in different historic periods in respect to political organization, military globalization, trade, finance, corporate productivity, migration, culture, and the environment. Each of these topics is covered in a chapter which contrasts the contemporary nature of globalization with that of earlier epochs. In mapping the shape and political consequences of globalization, the authors concentrate on six states in advanced capitalist societies (SIACS): the United States, the United Kingdom, Sweden, France, Germany, and Japan. For comparative purposes, other statesparticularly those with developing economicsare referred to and discussed where relevant. The book concludes by systematically describing and assessing contemporary globalization, and appraising the implications of globalization for the sovereignty and autonomy of SIACS. It also confronts directly the political fatalism that surrounds much discussion of globalization with a normative agenda that elaborates the possibilities for democratizing and civilizing the unfolding global transformation.
Foundations of Epidemiology has been widely used as an introductory text in a broad range of epidemiology courses. Minimal familiarity with statistics is assumed in the book. The text gives lucid, well-organized explanations of basic epidemiologic concepts such as rates and... FROM LONG DESCRIPTION.
What does strategy mean to the founder and CEO of a coaching and consulting company whose mission is to create inclusive and values-driven cultures where people can achieve their full potential while positively impacting society?How is sustainable strategic decision-making viewed by a former Member of the European Parliament?Developed in consultation with lecturers, students, and professionals, the research-driven process-practice model of strategy in Strategy: Theory, Practice, Implementation places implementation at its core, enabling students to develop a crystal-clear understanding of how strategy operates in aculture of dynamism, adaptability, and change.The authors' wealth of teaching, research, and practitioner experience shines through in their writing as they strike the perfect balance between clarity and rigour. They expertly cover all the core areas of strategy, using carefully paced, step-by-step guidance to apply theories and models ofstrategy to a diverse range of examples, making the text the most practical of its kind.Moving beyond the limits of traditional texts, Strategy offers unique Practitioner Insights (and accompanying video interviews) gathered from professionals engaged in a range of strategic roles, across multiple industries and sectors worldwide, to help students grasp the complex reality of strategicmanagement in practice.Strategy ultimately provides students with an empowering, critical, and highly practical approach to thinking, talking, and acting like a strategist.Online resources accompanying the textbook include:For registered adopters:- A test bank- PowerPoint slides- Answers to, or guidance on, the case study questions in the book- A series of 'Boardroom Challenges' for use in group role play exercises / action learning simulations- Teaching notes on using the 'Boardroom Challenges' in classFor students:- Practitioner insight video interviews, and further videos providing advice on how students can enhance their employability- Research Insights to broaden students' perspectives of academic research and its impact on strategic thinking- Links to articles, cases, chapters, or multimedia resources to support students' further reading- Additional case studies with exercises or discussion questions- MCQs- Guidance on how to analyse a case study- Flashcard glossary- Two additional chapters: Chapter 15 Designing effective strategy activities; Chapter 16 Strategy in practice: learning, reflecting, thinking
From the Department of Epidemiology at Johns Hopkins University and continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, comes the fully revised 6th Edition of Gordis Epidemiology. This bestselling text provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. New coverage includes expanded information on genetic epidemiology, epidemiology and public policy, and ethical and professional issues in epidemiology, providing a strong basis for understanding the role and importance of epidemiology in today's data-driven society. - Covers the basic principles and concepts of epidemiology in a clear, uniquely memorable way, using a wealth of full-color figures, graphs, charts, and cartoons to help you understand and retain key information. - Reflects how epidemiology is practiced today, with a new chapter organization progressing from observation and developing hypotheses to data collection and analyses. - Features new end-of-chapter questions for quick self-assessment, and a glossary of genetic terminology. - Provides more than 200 additional multiple-choice epidemiology self-assessment questions online. - Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.
The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.
The management of technological innovation (MTI) is one of the most important challenges facing businesses today. Innovation has become the fundamental driver of competitiveness for firms of all sizes in virtually all business sectors and nations. The first edition of this book has become one of the most popular texts for students of innovation and technology management. This new edition sees David Gann and Ammon Salter join Mark Dodgson as authors, drawing on their combined experience of 60 years of researching and teaching MTI. It combines the most relevant theoretical analysis with contemporary and historical empirical evidence to provide a comprehensive, yet concise and readable, guide to the challenges of MTI. By explaining the innovation process the book reveals the broad scope of MTI and its importance for company survival, growth and sustainability. It describes how MTI has to be managed strategically and how this is successfully achieved by formulating and implementing strategy and delivering value. Chapters provide frameworks, tools and techniques, and case studies on managing: innovation strategy, communities, and networks, R&D, design and new product and service development, operations and production, and commercialization. Based on robust analysis, the book provides a wide range of empirical evidence from a huge diversity of case studies, with around fifty case studies newly written for this edition. It analyses MTI in all parts of the world, in companies large and small, and in services, manufacturing, and resource-based business sectors. This new edition has been fully revised and updated to reflect the latest teaching and research, and to ensure its continuing relevance to the contemporary world of MTI. It will be an important resource for academics, students, and managers throughout the world, is a recommended text for students of innovation and technology management at postgraduate and undergraduate level, and is particularly valuable for MBA courses.
What is innovation? How is innovation used in business? How can we use it to succeed? Innovation - the ways ideas are made valuable - makes an important contribution to economic and social development, and is an increasingly topical issue. Not so long ago, there were no information technologies, commercial airlines, or television companies. Our parents were born into a world very different to today's, where television had yet to be invented, and there was no penicillin or frozen food. When our grandparents were born there were no internal combustion engines, aeroplanes, cinemas, or radios. In the last 150 years our world has been transformed - largely in part due to innovation. This Very Short Introduction looks at what innovation is and why it affects us so profoundly. It examines how it occurs, who stimulates it, how it is pursued, and what its outcomes are, both positive and negative. Innovation is hugely challenging and failure is common, yet it is essential to our social and economic progress. Mark Dodgson and David Gann consider the extent to which our understanding of innovation developed over the past century and how it might be used to interpret the global economy we all face in the future. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
The church in its first centuries split on whether Christ saved everyone or a few, Universalism versus Exclusivism. In the sixth century, the church settled the issue seemingly and held that Universalism was heresy. This book reviews this history as well as what provoked it--Scripture, on its face, gives two contradictory accounts of salvation's extent: everyone is ultimately saved and everyone is not. In contrast to both Exclusivism and Universalism, the book takes Scripture's two accounts of salvation's extent as true--that is, as a paradox. This is the approach the church has taken with other scriptural paradoxes. Saying one God is three, or one Son is both God and man, appeared to be contradictory too, but, to embrace Scripture entirely, these were seen as paradoxical. The Trinity modeled how one can be three, and the hypostatic union modeled how one can be two. For the paradox of salvation's extent, the answer lies in the individual's divisibility in the afterlife, one can be two. That is, in ultimate salvation, each individual can be both saved and unsaved.
In light of growing discourse on 'frugal innovation', this book offers novel approaches to innovation based on extensive empirical research. The study complements a decade of scholarly attention on frugal innovation by taking a research-based approach to innovation in resource-scarce and complex institutional contexts. The findings suggest that concepts such as frugal, reverse, jugaad, social, grassroots and inclusive innovation in fact represent heterogeneous assemblies of innovation for social, environmental and economic value. The conceptual framework invites attention to more plural sources and elements in the study of models of innovation to inspire further research in the fields of strategy, innovation, entrepreneurship, economic sociology and development studies. The design framework offers models, metrics and competencies for practitioners and policymakers to identify, evaluate and design frugal innovations. The comprehensive view of frugal innovation demonstrates how firms can implement globally competitive strategies by pursuing innovation for humanity to improve lives for everyone, everywhere.
We examine the extent to which developing countries that do little, if any, research and development themselves benefit from R&D that is performed in the industrial countries. By trading with an industrial country that has a large “stock of knowledge” from its cumulative R&D activities, a developing country can boost its productivity by importing a larger variety of intermediate products and capital equipment embodying foreign knowledge, and by acquiring useful information that would otherwise be costly to obtain. Our empirical results, which are based on observations over the 1971-90 period for 77 developing countries, suggest that R&D spillovers from the industrial countries in the North to the developing countries in the South are substantial.
This open access book offers a unique and practically oriented study of organisational and national conditions for implementing Responsible Research Innovation (RRI) policies and practices. It gives the reader a thorough understanding of the different aspects of RRI, and of barriers and drivers of implementation of RRI related policies. It shows how different organisational and national contexts provide unique challenges and opportunities for bringing RRI into practice. The book provides concrete examples and offers the reader both a theory-based understanding of the topic, as well as guidance for action. The target audience encompasses, in addition to RRI students and scholars in particular, all students and scholars in the field of Science and Technology Studies (STS). The book is also of interest to students and scholars in the fields of research ethics, philosophy of science, organisational governance in the research system and organisational theory more generally. Finally, the book is of use to practitioners in research conducting and funding organisations working to implement RRI.
How do firms grow? How do firms compete? An influential answer to these fundamental questions of business strategy lies in the concept of dynamic capabilities. David Teece provides a clear statement of his ideas, and a framework for managers wishing to assess their organization's strategy.
The innovation process is the most important of all business processes. Innovation is the means by which value is constructed and efficiencies are created. It is the source of sustainable competitive advantage. This book shows how the innovation process is changing profoundly. Part of the change results from the application of new technologies to the innovation process itself. A new category of technology has emerged which we call 'innovation technology'. This includes simulation and modelling, visualization, and rapid prototyping technologies. When used effectively, innovation technology makes the innovation process more economical and ameliorates some of its uncertainties. These technological changes are accompanied by changing organization structures and skills requirements. The technologies are used in fast moving, creative environments and are suited to project-based organization. They also require the development of new 'craft' skills to realize the possibilities created by the new 'code'. The book outlines a new way of thinking about innovation. Traditional definitions of 'research', 'development' and 'engineering', imply a progressive linearity which doesn't exist in reality. They are also associated with organizational departments, which are breaking down where once they existed, and are in any case non-existent in the vast majority of firms. They also fail to capture the central importance of design in innovation. We propose a new schema for the innovation process: Think, Play, Do. Innovation requires creating new ideas and thinking about new options, playing with them to see if they are practical, economical and marketable, and then doing: making the innovation real. This new schema captures the emerging innovation process using a more contemporary idiom. The book reports in-depth studies from a number of companies and sectors. Major case studies of Procter and Gamble and Arup Partners are presented. It reports on the use of innovation technology in a range of other companies and organizations, from pharmaceuticals in GSK, to engineering design in Ricardo engineering , and welding in TWI. We describe how innovation technology is used in traditional industries, such as in mining, and in public projects, such as the development of London's traffic congestion charge and the stabilization of the leaning tower of Pisa.
This title is a report of a follow up of a pan-Commonwealth forum of the same name held in Port of Spain Trinidad attended by over 28 Commonwealth small states. The study deals with the pressing economic policy question facing the world's smallest economies. Namely, how can small states enhance their industrial competitiveness and alleviate economic vulnerabilities associated with small country size.
This important book focuses on post-Lisbon Agenda issues of alignment and misalignment on different dimensions of European society and the European economy, including industrial systems, R&D systems, educational systems and job markets. It also looks in particular at the peripheral regions of Europe ? the less developed parts of ?old? Europe, the parts of old Europe that are outside or only half-inside the EU, the new member-states of the EU, and Turkey as the most important EU candidate country. It takes as its methodological starting point the theory of network alignment as developed in SPRU, notably by Nick von Tunzelmann, and builds on this to produce an incisive assessment of the institutions, individual actors and markets that drive the knowledge economy. In all of this, it sets the European picture firmly in the context of global developments in investment, labour and intellectual property flows. Key authors include the editor himself, von Tunzelmann, Andrea Salavetz of the Hungarian Academy of Sciences and Matija Rojec of the University of Ljubljana, Slovenia.
This book assesses the work, ideas, and influence of the doyen of business historians, Alfred Chandler, particularly on management innovation, strategy, organization, and finance.
What is going on when we are consciously aware of a visual scene, or hear sounds, or otherwise enjoy sensory experience? David Papineau argues controversially for a purely qualitative account: conscious sensory experiences are intrinsic states with no essential connection to external circumstances or represented properties.
This very valuable book collects together excellent empirical essays on what amounts to a silent majority in advanced industrial societies: low and medium tech manufacturing industries. Such industries employ more people and make a larger contribution to aggregate value creation than their more lauded high-tech counterparts and moreover, they constitute extremely important customer industries for such higher tech producers. They may be neglected, but they are not going away indeed, this volume shows that they are growing and adapting to the new competitive challenges of globalization. Attending to the dynamics of innovation and change in this large sector is crucial for understanding processes of social and economic restructuring in Europe today. The essays in this volume are the first place to look for insight into this extremely important area of political economic life in Europe. Gary Herrigel, University of Chicago, US Innovation in Low-Tech Firms and Industries challenges the currently fashionable notion that the advent of a knowledge-based economy demands that all social resources should be diverted to high-technology industries. Hirsch-Kreinsen and Jacobson point out these constitute a small part of even the most advanced economies. Attention has been diverted from the important innovation processes which occur in low and medium technology (LMT) sectors. This volume calls on us to achieve a much better and wiser balance in our industrial policy. Terrence McDonough, National University of Ireland, Galway The authors of this book make an urgently needed provocative point: ordinary engineering and technology ( low-tech ) continue to be of greater importance, in our knowledge society , than high-tech activities, and they may be similarly demanding by the competence they require and produce. This counteracts the exaggerated hype about high-tech firms or activities. The high-tech classification itself is highly arbitrary and often superficial. The authors show in what way low-tech activities and firms are important, and how they can be cultivated to buttress the economic strength of industrial and post-industrial nations. Researchers and policymakers, please take note! Arndt Sorge, Wissenschaftszentrum Berlin, Germany and University of Groningen, The Netherlands It is a general understanding that the advanced economies are currently undergoing a fundamental transformation into knowledge-based societies. There is a firm belief that this is based on the development of high-tech industries. Correspondingly, in this scenario low-tech sectors appear to be less important. A critique of this widely held belief is the starting point of this book. It is often overlooked that many of the current innovation activities are linked to developments inside the realm of low-tech. Thus the general objective of the book is to contribute to a discussion concerning the relevance of low-tech industries for industrial innovativeness in the emerging knowledge economy. Providing examples of both theoretical and empirical research in this area, Innovation in Low-tech Firms and Industries will be of great interest to postgraduate students and academic researchers in innovation studies. It will also appeal to policy makers in the field of innovation policy as well as industrial economists and sociologists interested in traditional industries in advanced economies.
The Lexicon brings together lexical material from a wide range of published and non-published sources to create an extensive compilation of the vocabulary of Fulfulde as it is spoken in that part of central Mali known as Masina (in Fulfulde, Maasina). The Lexicon is intended primarily for non-Fulfulde speakers who are learning the language at the intermediate or advanced levels and who need access to a comprehensive reference source on Fulfulde vocabulary. Scholars, development workers, and others whose research or fieldwork involves use of the Fulfulde of Masina may find it helpful as well in clarifying nuances of meaning and standardized spelling for the less familiar terms they might encounter. It is also intended that the present work, beyond the matter of organizing vocabulary, will contribute significantly to the expanding lexicographical and linguistic investigations of Fulfulde.
The authoritative guide for Data Monitoring Committees—fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim monitoring of data on safety and efficacy. Data Monitoring Committees (DMCs) are an essential component of many clinical trials, safeguarding trial participants and protecting the credibility and validity of the study. Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition offers practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees, providing a practical overview of the establishment, purpose, and responsibilities of these committees. Examination of topics such as the composition and independence of DMCs, statistical, philosophical and ethical considerations, and determining when a DMC is needed, presents readers with a comprehensive foundational knowledge of clinical trial oversight. Providing recent examples to illustrate DMC principles, this fully-updated guide reflects current developments and practices in clinical trial oversight and offers expanded coverage of emerging issues and challenges in the field. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. • Presents practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees • Illustrates the types of challenging issues Data Monitoring Committees face in practical situations • Provides updated and expanded coverage of topics including regulatory and funding agency guidelines and trial designs and their associated demands and limitations • Includes a new chapter addressing legal issues that affect DMC members and discusses general litigation concerns relevant to clinical research • Expands treatment of current journal publications addressing DMC issues Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition is a must-have text for anyone engaged in DMC activities as well as trial sponsors, clinical trial researchers, regulatory and bioethics professionals, and those associated with clinical trials in academic, government and industry settings.
This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart
A valuable resource for researchers and workers in the fields of both pharmaceuticals and biotechnology as well as undergraduates in biochemistry, applied biology, biomedical sciences and pharmacy, this book compares established techniques of antibody production with the new. Antibody structure and the implications of antibody engineering are fully discussed, and a case study approach illustrates how antibodies are finding increasing use in the diagnosis and treatment of disease. The volume ends with commercial expression, purification and large-scale manufacture of antibodies and their future potential, particularly as therapeutic agents.
Written by a team of leading international scholars, this new book treats entrepreneurship as an ever-evolving social phenomenon, and explores the recent trends that impact it, such as: digitisation; disruptive technologies; the rise of the ′gig′ economy and; the growing importance of community-based and social entrepreneurship. Including a mixture of case studies, examples, consideration of policy issues and exercises, this text provides practical perspectives of Entrepreneurship in support of key theory, while discussion questions, suggested reading and assignments help situate and test understanding.
Is neoclassical economics dead? Why have the biggest industrial economies stagnated since the financial crisis? Is the competitive threat from China a tired metaphor or a genuine danger to our standard of living? Lord David Sainsbury draws on his experience in business and government to assemble the evidence and comes to some startling conclusions. In Windows of Opportunity, he argues that economic growth comes not as a steady process, but as a series of jumps, based on investment in high value-added firms. Because these firms are engaged in winner-takes-all competition, rapid growth in one country can indeed come at the expense of growth in another, contrary to the standard models. He suggests a new theory of growth and development, with a role for government in 'picking winners' at the level of technologies and industries rather than individual firms. With the role of industrial policy at the centre of the Brexit debate, but a significant intellectual gap in setting out what that policy should be, this book could not be more timely.
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