Nonlinear measurement data arise in a wide variety of biological and biomedical applications, such as longitudinal clinical trials, studies of drug kinetics and growth, and the analysis of assay and laboratory data. Nonlinear Models for Repeated Measurement Data provides the first unified development of methods and models for data of this type, with a detailed treatment of inference for the nonlinear mixed effects and its extensions. A particular strength of the book is the inclusion of several detailed case studies from the areas of population pharmacokinetics and pharmacodynamics, immunoassay and bioassay development and the analysis of growth curves.
The measured and passionate essays in this volume bring to contemporary debates about educational research both a first-hand familiarity with the practices and arguments of the educational research community and a clear grasp of the ways in which philosophical sources and analysis can inform them. It will be essential reading for researchers, masters and doctoral students who are coming to terms with educational research.
This book is a comprehensive treatment of fine particle magnetism and the magnetic properties of rocks. Starting from atomic magnetism and magneotistic principles, the authors explain why domains and micromagnetic structures form in ferrmagnetic crystals and how these lead to magnetic memory in the form of thermal, chemical and other remanent magnetizations. This book will be of value to graduate students and researchers in geophysics and geology, particularly in palemagnetism and rock magnetism, as well as physicists and electrical engineers interested in fine-particle magnetism and magnetic recording.
Repeated measures data arise when the same characteristic is measured on each case or subject at several times or under several conditions. There is a multitude of techniques available for analysing such data and in the past this has led to some confusion. This book describes the whole spectrum of approaches, beginning with very simple and crude methods, working through intermediate techniques commonly used by consultant statisticians, and concluding with more recent and advanced methods. Those covered include multiple testing, response feature analysis, univariate analysis of variance approaches, multivariate analysis of variance approaches, regression models, two-stage line models, approaches to categorical data and techniques for analysing crossover designs. The theory is illustrated with examples, using real data brought to the authors during their work as statistical consultants.
This monograph provides a careful review of the major statistical techniques used to analyze regression data with nonconstant variability and skewness. The authors have developed statistical techniques--such as formal fitting methods and less formal graphical techniques-- that can be applied to many problems across a range of disciplines, including pharmacokinetics, econometrics, biochemical assays, and fisheries research. While the main focus of the book in on data transformation and weighting, it also draws upon ideas from diverse fields such as influence diagnostics, robustness, bootstrapping, nonparametric data smoothing, quasi-likelihood methods, errors-in-variables, and random coefficients. The authors discuss the computation of estimates and give numerous examples using real data. The book also includes an extensive treatment of estimating variance functions in regression.
Drawing on the authors' varied experiences working and teaching in the field, Analysis of Multivariate Social Science Data, Second Editionenables a basic understanding of how to use key multivariate methods in the social sciences. With updates in every chapter, this edition expands its topics to include regression analysis, con
This chronologically organized book is the first to provide comprehensive coverage of forfeits and successful protests of major league baseball games, educating the reader on the rules and prevailing styles of play at the time that each of the games was played. In addition to the date, location, and source information, this work provides capsule biographies of many of the principal characters involved (including, for instance, the obscure one-game umpire who perpetrated the first forfeited game in major league history in 1871).
This monograph provides an up-to-date discussion of analysis strategies for regression problems in which predictor variables are measured with errors. The analysis of nonlinear regression models includes generalized linear models, transform-both-sides models and quasilikelihood and variance function problems. The text concentrates on the general ideas and strategies of estimation and inference rather than being concerned with a specific problem. Measurement error occurs in many fields, such as biometry, epidemiology and economics. In particular, the book contains a large number of epidemiological examples. An outline of strategies for handling progressively more difficult problems is also provided.
Professor Palliser focuses here on towns in England in the centuries between the Norman Conquest and the Tudor period, on which he is an acknowledged authority. Urban topography, archaeology, economy, society and politics are all brought under review, and particular attention is given to relationships between towns and the Crown, to the evidence for migration into towns, and to the vexed question of urban fortunes in the 15th and 16th centuries. Two essays set urban history in a broader framework by considering recent work on town and village formation and on the development of parishes. The collection includes two hitherto unpublished studies and is introduced and put in context by a new survey of English towns from the 7th to the 16th centuries.
Mania takes you into the world of the young rebels who transformed American culture in the 1950s-a world of sex, drugs, jazz, crime, insanity, and a defiant new literature. It tells the story of Lucien Carr's killing of David Kammerer, the car chase that led to Allen Ginsberg's committal to a mental asylum, William S. Burroughs' heroin addiction and deadly "William Tell act," Jack Kerouac's seven-year struggle to publish On The Road, and the creation of Ginsberg's ecstatic masterpiece "Howl," which the authorities declared obscene and fought fervently to suppress. It is a story too unbelievable to make up. Book jacket.
This book offers an introduction to the field of complexity and landscape ecology. It covers such topics as connectivity, criticality, feedback, and networks, as well as their impact on the stability and predictability of ecosystem dynamics.
Although a great deal has been published on the economic, social and engineering history of nineteenth-century railways, the work of historical geographers has been much less conspicuous. This overview by David Turnock goes a long way towards restoring the balance. It details every important aspect of the railway’s influence on spatial distribution of economic and social change, providing a full account of the nineteenth-century geography of the British Isles seen in the context of the railway. The book reviews and explains the shape of the developing railway network, beginning with the pre-steam railways and connections between existing road and water communications and the new rail lines. The author also discusses the impact of the railways on the patterns of industrial, urban and rural change throughout the century. Throughout, the historical geography of Ireland is treated in equal detail to that of Great Britain.
Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.
Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. - Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context - Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research - Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA
Burned in a barrel of tar! Brighton’s Historical Horrors Revealed! Brighton scandals including rioting rockers, military misdemeanours and three terrible trunk murders! Strike! Barbarity at the Battle of Lewes Road. Baptised then beheaded: Stories of Saxon savagery! Strafed by Nazi machine-gunners: The terrible true tale of the Brighton blitz! Containing more than 60 illustrations and 2,000 years of history, here is the dark and dreadful saga of Brighton. With bombs and battles, riots and rebellions, tidal waves, terrors, and some terrible true crimes, it is no wonder that the city was once dubbed ‘The Queen of Slaughtering Places’!
Since ROC curves have become ubiquitous in many application areas, the various advances have been scattered across disparate articles and texts. ROC Curves for Continuous Data is the first book solely devoted to the subject, bringing together all the relevant material to provide a clear understanding of how to analyze ROC curves.The fundamenta
How do quantitative methods help us to acquire knowledge of the real world? What are the `do′s′ and `don′ts′ of effective quantitative research? This refreshing and accessible book provides students with a novel and useful resource for doing quantitative research. It offers students a guide on how to: interpret the complex reality of the social world; achieve effective measurement; understand the use of official statistics; use social surveys; understand probability and quantitative reasoning; interpret measurements; apply linear modelling; understand simulation and neural nets; and integrate quantitative and qualitative modelling in the research process. Jargon-free and written with the needs of students in mind, the book will be required reading for students interested in using quantitative research methods.
One of the most compelling issues in public education involves what it means for schools to be public. Are they public in funding or public in oversight and control? Are they public in the values they convey or in the standards they set? Are they public in deciding curriculum or only in access to space? David Matthews probes these issues in 19th century Alabama in ways that no one else has attempted. And he provides lessons from the past that can inform the present and future.
This book examines key concepts and analytical approaches in complexity theory as it applies to landscape ecology, including complex networks, connectivity, criticality, feedback, and self-organisation. It then reviews the ways that these ideas have led to new insights into the nature of ecosystems and the role of processes in landscapes. The updated edition explores innovations in ecotechnology, including automated monitoring, big data, simulation and machine learning, and shows how they are revolutionizing ecology by making it possible to deal more effectively with complexity. Addressing the topic in a progression of ideas from small to large, and from simple to sophisticated, the book examines the implications of complexity for major environmental issues of our time, particularly the urgencies of climate change and loss of biodiversity. Understanding ecological complexity is crucial in today’s globalized and interconnected world. Successful management of the world’s ecosystems must combine models of ecosystem complexity with biodiversity, environmental, geographic, and socioeconomic data. The book examines the impact of humans on landscapes and ecosystems, as well as efforts to embed sustainability, commerce and industrial development in the larger context of ecosystem services and ecological economics. Well-established as researchers in the field, the authors provide a new perspective on current and future understanding of complexity in landscape ecology. The new edition offers a non-technical account of the topic, so it is both accessible and informative for general readers. For students of ecology, it provides a fresh approach to classical ideas.
Following in the footsteps of its bestselling predecessors, the Handbook of Parametric and Nonparametric Statistical Procedures, Fifth Edition provides researchers, teachers, and students with an all-inclusive reference on univariate, bivariate, and multivariate statistical procedures.New in the Fifth Edition:Substantial updates and new material th
The history of capitalism is not to be explained in mere economic terms. David Harris Sacks here demonstrates that the modern Western economy was ushered in by broad processes of social, political, and cultural change. His study of Bristol as it opened it gate to national politics and the Atlantic economy reveals capitalism to be not just a species of economic order but a distinct form of life, governed by its own ethical norms and cultural practices. Availing himself of the methods of "thick description," socio-economic analysis, and political theory, Sacks examines the dynamics by which early modern Bristol moved from a medieval commercial economy to an early capitalist one. Throughout the period, the life of the city depended heavily on the successes of its great overseas merchants. But their quest for a monopoly of trade with the outside world, from the Atlantic seaboard to the Levant, came into conflict with the concerns of Bristol's artisans and retail shopkeepers. The battles of the two factions conditioned social and cultural developments in Bristol for two centuries. Locally, the conflict set the terms for developing conceptions of justice and authority. On a larger scale, it drew the community firmly into the great affairs of the realm and the wider world of expanding markets beyond. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1992. The history of capitalism is not to be explained in mere economic terms. David Harris Sacks here demonstrates that the modern Western economy was ushered in by broad processes of social, political, and cultural change. His study of Bristol as it opened i
In medieval and early modern Britain, people would refer to their local district as their 'country', a term now largely forgotten but still used up until the First World War. Core groups of families that remained rooted in these 'countries', often bearing distinctive surnames still in use today, shaped local culture and passed on their traditions. In The Grass Roots of English History, David Hey examines the differing nature of the various local societies that were found throughout England in these periods. The book provides an update on the progress that has been made in recent years in our understanding of the history of ordinary people living in different types of local societies throughout England, and demonstrates the value of studying the varied landscapes of England, from towns to villages, farmsteads, fields and woods to highways and lanes, and historic buildings from cathedrals to cottages. With its broad coverage from the medieval period up to the Industrial Revolution, the book shows how England's socio-economic landscape had changed over time, employing evidence provided by archaeology, architecture, botany, cultural studies, linguistics and historical demography. The Grass Roots of English History provides an up-to-date account of the present state of knowledge about ordinary people in local societies throughout England written by an authority in the field, and as such will be of great value to all scholars of local and family history.
Of all the decisions a new parent makes, choosing that special name is the most significant and the most rewarding. A new reference book for prospective parents, this clear, helpful and easy-to-use A-Z guide gives you thousands of brilliant suggestions for picking the perfect name for your new arrival. It also includes appendices of the top ten names through the centuries and the most popular celebrity names.
This monograph contains many ideas on the analysis of survival data to present a comprehensive account of the field. The value of survival analysis is not confined to medical statistics, where the benefit of the analysis of data on such factors as life expectancy and duration of periods of freedom from symptoms of a disease as related to a treatment applied individual histories and so on, is obvious. The techniques also find important applications in industrial life testing and a range of subjects from physics to econometrics. In the eleven chapters of the book the methods and applications of are discussed and illustrated by examples.
An up-to-date, comprehensive account of major issues in finitemixture modeling This volume provides an up-to-date account of the theory andapplications of modeling via finite mixture distributions. With anemphasis on the applications of mixture models in both mainstreamanalysis and other areas such as unsupervised pattern recognition,speech recognition, and medical imaging, the book describes theformulations of the finite mixture approach, details itsmethodology, discusses aspects of its implementation, andillustrates its application in many common statisticalcontexts. Major issues discussed in this book include identifiabilityproblems, actual fitting of finite mixtures through use of the EMalgorithm, properties of the maximum likelihood estimators soobtained, assessment of the number of components to be used in themixture, and the applicability of asymptotic theory in providing abasis for the solutions to some of these problems. The author alsoconsiders how the EM algorithm can be scaled to handle the fittingof mixture models to very large databases, as in data miningapplications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and patternrecognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied andtheoretical statisticians as well as for researchers in the manyareas in which finite mixture models can be used to analyze data.
Buddhism is essentially a teaching about liberation - from suffering, ignorance, selfishness and continued rebirth. Knowledge of 'the way things really are' is thought by many Buddhists to be vital in bringing about this emancipation. This book is a philosophical study of the notion of liberating knowledge as it occurs in a range of Buddhist sources. Buddhism, Knowledge and Liberation assesses the common Buddhist idea that knowledge of the three characteristics of existence (impermanence, not-self and suffering) is the key to liberation. It argues that this claim must be seen in the context of the Buddhist path and training as a whole. Detailed attention is also given to anti-realist, sceptical and mystical strands within the Buddhist tradition, all of which make distinctive claims about liberating knowledge and the nature of reality. David Burton seeks to uncover various problematic assumptions which underpin the Buddhist worldview. Sensitive to the wide diversity of philosophical perspectives and interpretations that Buddhism has engendered, this book makes a serious contribution to critical and philosophically aware engagement with Buddhist thought. Written in an accessible style, it will be of value to those interested in Buddhist Studies and broader issues in comparative philosophy and religion.
Called the "bible of applied statistics," the first two editions of the Handbook of Parametric and Nonparametric Statistical Procedures were unsurpassed in accessibility, practicality, and scope. Now author David Sheskin has gone several steps further and added even more tests, more examples, and more background information-more than 200 pages of n
An Introduction to Universal Artificial Intelligence provides the formal underpinning of what it means for an agent to act intelligently in an unknown environment. First presented in Universal Algorithmic Intelligence (Hutter, 2000), UAI offers a framework in which virtually all AI problems can be formulated, and a theory of how to solve them. UAI unifies ideas from sequential decision theory, Bayesian inference, and algorithmic information theory to construct AIXI, an optimal reinforcement learning agent that learns to act optimally in unknown environments. AIXI is the theoretical gold standard for intelligent behavior. The book covers both the theoretical and practical aspects of UAI. Bayesian updating can be done efficiently with context tree weighting, and planning can be approximated by sampling with Monte Carlo tree search. It provides algorithms for the reader to implement, and experimental results to compare against. These algorithms are used to approximate AIXI. The book ends with a philosophical discussion of Artificial General Intelligence: Can super-intelligent agents even be constructed? Is it inevitable that they will be constructed, and what are the potential consequences? This text is suitable for late undergraduate students. It provides an extensive chapter to fill in the required mathematics, probability, information, and computability theory background.
In the Nature of Landscape presents regional cultural landscape as a new direction for research in cultural geography. Represents the first cultural geographic study of the Norfolk Broads region of eastern England Addresses regional cultural landscape through consideration of narratives of landscape origin, debates over human conduct, the animal and plant landscapes of the region, and visions of the ends of landscape through pollution and flood Draws upon in-depth original research, spanning almost two decades of archival work, interviews, and field study Covers a great diversity of topics, from popular culture to scientific research, folk song to holiday diaries, planning survey to pioneering photography, and ornithology to children’s literature Features a variety of illustrative material, including original photographs, paintings, photography, advertising imagery, scientific diagrams, maps, and souvenirs
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