The second son of Johann Sebastian Bach, C.P.E. Bach was an important composer in his own right, as well as a writer and performer on keyboard instruments. He composed roughly a thousand works in all the leading genres of the period, with the exception of opera, and Haydn, Mozart and Beethoven all acknowledged his influence. He was also the author of a two-volume encyclopedic book about performance on keyboard instrument. C.P.E. Bach and his music have always been the subject of significant scholarship and publication but interest has sharply increased over the past two or three decades from performers as well as music historians. This volume incorporates important writings not only on the composer and his chief works but also on theoretical issues and performance questions. The focus throughout is on relatively recent scholarship otherwise available only in hard-to-access sources.
Published in conjunction with a New York Historical Society exhibition, this photo-filled, pocket-sized guidebook by a "New York Times reporter covers 1,079 houses of worship in New York City. 899 photos & 24 maps.
The thousands uprooted and displaced by the Holocaust had a profound cultural impact on the countries in which they sought refuge, with numerous Holocaust escapees attaining prominence as scientists, writers, filmmakers and artists. But what is less well known is the way in which this refugee diaspora shaped the scholarly culture of their new-found homes and international policy. In this unique work, David Simon explores the pioneering role played by mostly Jewish refugee scholars in the creation of development studies and practice following the Second World War, and what we can learn about the discipline by examining the social and intellectual history of its early practitioners. Through in-depth interviews with key figures and their relatives, Simon considers how the escapees' experiences impacted their scholarship, showing how they played a key role in shaping their belief that ‘development’ really did hold the potential to make a better world, free from the horrors of war, genocide and discrimination they had experienced under Nazi rule. In the process, he casts valuable new light on the origins and evolution of development studies, policy and practice from this formative postwar period to the present.
Bach has remained a figure of continuous fascination and interest to scholars and readers since the original Master Musicians Bach volume's publication in 1983 - even since its revision in 2000, understanding of Bach and his music's historical and cultural context has shifted substantially. Reflecting new biographical information that has only emerged in recent decades, author David Schulenberg contributes to an ongoing scholarly conversation about Bach with clarity and concision. Bach traces the man's emergence as a startlingly original organist and composer, describing his creative evolution, professional career, and family life from contemporary societal and cultural perspectives in early modern Europe. His experiences as student, music director, and teacher are examined alongside the music he produced in each of these roles, including early compositions for keyboard instruments, the great organ and harpsichord works of later years, vocal music, and other famous instrumental works, including the Brandenburg Concertos. Schulenberg also illuminates how Bach incorporated his contemporary environment into his work: he responded to music by other composers, to his audiences and employment conditions, and to developments in poetry, theology, and even the sciences. The author focuses on Bach's evolution as a composer by ultimately recognizing "Bach's world" in the specific cities, courts, and environments within and for which he composed. Dispensing with biographical minutiae and more closely examining the interplay between his life and his music, Bach presents a unique, grounded, and refreshing new framing of a brilliant composer.
Through the story of Lucy a woman born of rape, this narrative sensitively explores racism, poverty and oppression in a tumultuous cosmopolitan society which, redolent of genteel pretensions and human tragedy, searches for catharsis through annual carnival abandon. Spanning 150 years from post slavery to post-colonial times, this shimmering yet gritty tale unfolds against the background of declining old cocoa and sugar plantations and gushing new oil wells in the tropical Caribbean island of Trinidad. A fascinating amalgam of history and heart-wrenching drama skilfully woven together by author Bertille David-Allahar, this novel captures the odyssey of Lucy and other women of colour, through an intimate portraiture of awakening, endurance and coming of age in a stratified island society still haunted by the shadows of slavery.
The first book in nearly a century dedicated to a close examination of the musical works of Wilhelm Friedemann Bach, first son of Johann Sebastian Bach.
The “gripping” true story of the founder of psychoanalysis—and how he made it out of Austria after the Nazi takeover (The Independent). Sigmund Freud was not a practicing Jew, but that made no difference to the Nazis as they burned his books in the early 1930s. Goebbels and Himmler wanted all psychoanalysts, especially Freud, dead, and after the annexation of Austria, it became clear that Freud needed to leave Vienna. But a Nazi raid on his house put the Freuds’ escape at risk. With never-before-seen material, this biography reveals details of the last two years of Freud’s life, and the people who helped him in his hour of need—among them Anton Sauerwald, who defied his Nazi superiors to make the doctor’s departure possible. The Escape of Sigmund Freud also delves into the great thinker’s work, and recounts the arrest of Freud’s daughter, Anna, by the Gestapo; the dramatic saga behind the signing of Freud’s exit visa and his eventual escape to London; and how the Freud family would have an opportunity to save Sauerwald’s life in turn. “Full of fascinating insights and anecdotes . . . Cohen draws copiously on the correspondence between Freud and [his nephew] Sam to paint a vivid picture of their complex and deeply troubled family.” —Daily Mail “An illuminating look at the end of the life of a giant of psychology.” —Kirkus Reviews
State police officer Lt. Tom Provens is the lead officer investigating a brutal child prostitution ring. The investigation begins with a desperate 911 call and the discovery of the bodies of three young girls in an abandoned mansion in Massachusetts. Provens enters the evil universe of Sir William, a world of heartless enforcers, greedy landlords, and tortured children abducted off the streets and forced to become sex slaves. Unraveling this web takes Provens and the father of a missing ten-year-old girl on a desperate international journey, ending in the unforgiving jungles of the Amazon Valley.
General Circulation Models (GCMs) are rapidly assuming widespread use as powerful tools for predicting global events on time scales of months to decades, such as the onset of EL Nino, monsoons, soil moisture saturation indices, global warming estimates, and even snowfall predictions. While GCMs have been praised for helping to foretell the current El Nino and its impact on droughts in Indonesia, its full power is only now being recognized by international scientists and governments who seek to link GCMs to help them estimate fish harvests, risk of floods, landslides, and even forest fires.Scientists in oceanography, hydrology, meteorology, and climatology and civil, ocean, and geological engineers perceive a need for a reference on GCM design. In this compilation of information by an internationally recognized group of experts, Professor Randall brings together the knowledge base of the forerunners in theoretical and applied frontiers of GCM development. General Circulation Model Development focuses on the past, present, and future design of numerical methods for general circulation modeling, as well as the physical parameterizations required for their proper implementation. Additional chapters on climate simulation and other applications provide illustrative examples of state-of-the-art GCM design.Key Features* Foreword by Norman Phillips* Authoritative overviews of current issues and ideas on global circulation modeling by leading experts* Retrospective and forward-looking chapters by Akio Arakawa of UCLA* Historical perspectives on the early years of general circulation modeling* Indispensable reference for researchers and graduate students
An “entertaining and informative” comprehensive guide to 240 classical composers and their music—from the medieval era to the modern age (Library Journal). Music, according to Aaron Copland, can thrive only if there are “gifted listeners.” But today’s listeners must choose between classical and rock, opera and rap, and the choices can seem overwhelming at times. In The Essential Canon of Classical Music, David Dubal comes to the aid of the struggling listener and provides a cultural-literacy handbook for classical music. Dubal identifies the 240 composers whose works are most important to an understanding of classical music and offers a comprehensive, chronological guide to their lives and works. He has searched beyond the traditional canon to introduce readers to little—known works by some of the most revered names in classical music—Bach, Haydn, Mozart, Schubert—as well as to the major works of lesser-known composers. In a spirited and opinionated voice, Dubal seeks to rid us of the notion of “masterpieces” and instead to foster a new generation of master listeners. The result is an uncommon collection of the wonders classical music has to offer.
Featuring Contributions by: Will Murray, Brenda Seabrooke, Arthur Hall, Steven Philip Jones, Dan Rowley and Don Baxter, David Marcum, Hugh Ashton, Sonya Kudei, Barry Clay, DJ Tyrer, Mark Wardecker, Paul Hiscock, Tom Turley, Brett Fawcett, Martin Daley, Bob Byrne, Tracy J. Revels, James Gelter, and Matthew White, with a poem by Kevin Patrick McCann, and forewords by Michael Sims, Roger Johnson, Emma West, Steve Emecz, and David Marcum. 59 New Traditional Canonical Holmes Adventures Collected in Three Companion Volumes In 2015, the first three volumes of The MX Book of New Sherlock Holmes Stories arrived, containing over 60 stories in the true traditional Canonical manner, revisiting Holmes and Watson in those days where it is "always 1895" . . . or a few decades on either side of that. That was the largest collection of new Holmes stories ever assembled, and originally planned to be a one-time event. But readers wanted more, and the contributors had more stories from Watson's Tin Dispatch Box, so the fun continued. Now, with the release of Parts XXXVII, XXXVIII, and XXXIX, the series has grown to over 800 new Holmes adventures by over 200 contributors from around with world. Since the beginning, all contributor royalties go to the Undershaw school for special needs children, located at one of Sir Arthur Conan Doyle's former homes, and to date the project has raised over $110,000 for the school. This new collection of 59 adventures features Holmes and Watson carrying out their masterful investigations from the early days of their friendship in Baker Street to the post-War years during Holmes's retirement. Along the way, Our Heroes are involved in dozens of fascinating mysteries - some relating Untold Cases, sequels to Canonical adventures, and a number or others that progress along completely unexpected lines. Join us as we return to Baker Street and discover more authentic adventures of Sherlock Holmes, described by the estimable Dr. Watson as "the best and wisest . . . whom I have ever known.
The 1970s: Vietnam, Watergate, inflation, and social unrest. Those were the days! On January 12, 1971, a new television series premiered that would address such topics in a comical and satirical manner. The series would sit at the top of the ratings for the majority of its run, redefining the structure of situation comedy, and would go on to be one of the most influential sitcoms in television history. All in the Family dominated the airwaves in the 1970s and reflected an ever-changing society during one of America’s most challenging decades. David Maska assesses the entire series, season by season, and how it continued to evolve and fit into television’s landscape from its inception in the late 1960s as a pilot that nobody wanted to touch, through its celebrated run as the number one show in America, and finally its demise as Archie Bunker’s Place in the early 1980s. With an annotated episode guide for all 13 total seasons (over 300 episodes!), this is a book you can keep next to you for reference while you watch and enjoy this classic series.
The Jewish Labor Bund was one of the major political forces in early twentieth-century Eastern Europe. But the decades after the Second World War were years of enormous difficulty for Bundists. Like millions of other European Jews, they faced the challenge of resurrecting their lives, so gravely disrupted by the Holocaust. Not only had the organization lost many members, but its adherents were also scattered across many continents. In this book, David Slucki charts the efforts of the surviving remnants of the movement to salvage something from the wreckage. Covering both the Bundists who remained in communist Eastern Europe and those who emigrated to the United States, France, Australia, and Israel, the book explores the common challenges they faced—building transnational networks of friends, family, and fellow Holocaust survivors, while rebuilding a once-local movement under a global umbrella. This is a story of resilience and passion—passion for an idea that only barely survived Auschwitz.
Griffith's work results from many interviews with side-men in big bands of the early 1930's and early 40's, including Curtis Jones, Bill Dillard and Cliff Olson. Here the author brings a fresh perspective to the rich legacy they left behind them.
Praise for Amish Grace "A story our polarized country needs to hear: It is still grace that saves." —BILL MOYERS, Public Affairs Television "In a world where repaying evil with evil is almost second nature, the Amish remind us there's a better way. In plain and beautiful prose, Amish Grace recounts the Amish witness and connects it to the heart of their spirituality." —SISTER HELEN PREJEAN, author, Dead Man Walking "Faced with the notorious Amish aversion to publicity, reporter after reporter turned to the authors...to answer one question: How could the Nickel Mines Amish so readily, so completely, forgive ? While the text provides a detailed account of the tragedy, its beauty lies in its discovery of forgiveness as the crux of Amish culture. Never preachy or treacly, it suggests a larger meditation more than apt in our time." —Philadelphia Magazine "This balanced presentation . . .blends history, current evaluation of American society, and an examination of what builds community into a seamless story that details the shootings while it probes the religious beliefs that led to such quick forgiving. Recommended." —Library Journal "Professors Kraybill, Nolt, and Weaver-Zercher have written a superb book—a model of clear, forceful writing about a tragedy and its aftermath. They have an obvious affection for the Amish yet ask tough questions, weigh contradictions, and explore conundrums such as how a loving God could permit schoolgirls to be massacred." —National Catholic Reporter Visit the authors' Web site at www.amishgrace.com
Why," an exasperated Jonathan Edwards asked, "can't we be contented with. . . the canon of Scripture?" Edwards posed this query to the religious enthusiasts of his own generation, but he could have just as appropriately put it to people across the full expanse of early American history. In the minds of her critics, Anne Hutchinson's heresies threatened to produce "a new Bible." Ethan Allen insisted that a revelation which spoke to every circumstance of life would require "a Bible of monstrous size." When the African-American prophetess Rebecca Jackson embarked on a spiritual journey toward Shakerism, she dreamt of a home in which she could find multiple books of scripture. Orestes Brownson explained to his skeptical contemporaries that the idea drawing him to Catholicism was the prospect of an "ever enlarging volume" of inspiration. Early Americans of every color and creed repeatedly confronted the boundaries of scripture. Some fought to open the canon. Some worked to keep it closed. Sacred Borders vividly depicts the boundaries of the biblical canon as a battleground on which a diverse group of early Americans contended over their differing versions of divine truth. Puritans, deists, evangelicals, liberals, Shakers, Mormons, Catholics, Seventh-day Adventists, and Transcendentalists defended widely varying positions on how to define the borders of scripture. Carefully exploring the history of these scriptural boundary wars, Holland offers an important new take on the religious cultures of early America. He presents a colorful cast of characters-including the likes of Franklin and Emerson along with more obscure figures--who confronted the intellectual tensions surrounding the canon question, such as that between cultural authority and democratic freedom, and between timeless truth and historical change. To reconstruct these sacred borders is to gain a new understanding of the mental world in which early Americans went about their lives and created their nation.
A comprehensive guide to the world's largest financial market Foreign exchange is the world's largest financial market and continues to grow at a rapid pace. As economies intertwine and currencies fluctuate there is hardly a corporate entity that doesn't need to use options on foreign exchange to hedge risk or increase returns. Moreover, currency options, both vanilla and exotic, are part of standard toolkit of professional portfolio managers and hedge funds. Written by a practitioner with real-world experience in this field, the Third Edition of Options on Foreign Exchange opens with a substantive discussion of the spot and forward foreign exchange market and the mechanics of trading currency options. The Black-Scholes-Merton option-pricing model as applied to currency options is also covered, along with an examination of currency futures options. Throughout the book, author David DeRosa addresses the essential elements of this discipline and prepares you for the various challenges you could face. Updates new developments in the foreign exchange markets, particularly regarding the volatility surface Includes expanded coverage of the currency crises and capital controls, electronic trading, forward contracts, exotic options, and more Employs real-world terminology so you can a firm understanding of this dynamic marketplace The only way to truly succeed in today's foreign exchange market is by becoming more familiar with currency options. The Third Edition of Options on Foreign Exchange will help you achieve this goal and put you in better position to make more profitable decisions in this arena.
It was a hot summer day, and a boy is playing on the steps of a local church in his neighborhood. He checks the door to see if it's open, looking for a drink of water or a temporary escape from the heat of the day. The door opens, introducing a beautiful garden. As he begins to explore, he meets talking animals and the first man. Later he meets the Creator Himself and discovers that the Creator had been looking for him. He also meets a serpent-type creature that follows him out of the garden and tries to make his life a wreck. A venture into an unknown garden forever changes the lives of so many when a boy discovers Abba's Garden.
Numerical weather prediction models play an increasingly important role in meteorology, both in short- and medium-range forecasting and global climate change studies. The most important components of any numerical weather prediction model are the subgrid-scale parameterization schemes, and the analysis and understanding of these schemes is a key aspect of numerical weather prediction. This book provides in-depth explorations of the most commonly used types of parameterization schemes that influence both short-range weather forecasts and global climate models. Several parameterizations are summarised and compared, followed by a discussion of their limitations. Review questions at the end of each chapter enable readers to monitor their understanding of the topics covered, and solutions are available to instructors at www.cambridge.org/9780521865401. This will be an essential reference for academic researchers, meteorologists, weather forecasters, and graduate students interested in numerical weather prediction and its use in weather forecasting.
Northern Exposures' is an important and thought-provoking book that shows how the labor movement has embraced environmental protection and is beginning to create a new and more sustainable vision for the future. Dave Bennett's knowledge and commitment shine through. He is, by turns, the skeptical philosopher sifting the evidence and the passionate partisan arguing for the rights of the people. It makes for a rich and exhilarating mixture.-Nigel Crisp, Permanent Secretary, U.K. Department of Health, and Chief Executive, National Health Service (2000-2006), Author, Turning the World Upside Down: The Search for Global Health in the 21st Century (Royal Society of Medicine Press, 2010)
Originally published in 1985, and available for the first time in paperback, Bondmen & Rebels provides a pioneering study of slave resistance in the Americas. Using the large-scale Antigua slave conspiracy of 1736 as a window into that society, David Barry Gaspar explores the deeper interactive character of the relation between slave resistance and white control.
1936: Harald Mason, a German-born naturalised British airman, is sent by a concerned Foreign Office to Berlin to unearth Luftwaffe expansion plans and investigate the sustainability of high-octane aviation fuel supply in time of war. Werner Scribner, a technical draftsman at the new Luftwaffe Air Ministry in Berlin, is determined to bring down the Anti-Christ Hitler. A narrative of disparate characters, from the leonine intelligence chief Major Alastair Cartwright MC in London to the clever and elegant Elisabeth Schneider, economist and Soviet spy, this is a story of American business funding Nazi Germany and the rebuilding of Soviet Russia, as part of President Franklin D. Roosevelt's New Deal programme.
Is death inevitable? Until now, the history of mankind has been marked by this fatal fact. Religions, borders and progress are born from an ancient fear of death, comfort from this fear man often found only in religious paradigms. But according to José Luis Cordeiro and David Wood, the incontrovertible fact of death is no longer an absolute certainty - science and technology are preparing to tear down the final frontier: that of immortality. This accessible book provides insight into recent exponential advances in artificial intelligence, tissue regeneration, stem cell treatment, organ printing, cryopreservation, and genetic therapies that, for the first time in human history, offer a realistic chance to solve the problem of the aging of the human body. In this book, Cordeiro and Wood not only present all the major developments, initiatives, and ideas for eternal life, they also show why there are a number of good arguments for seeing death for what it is: the last undefeated disease. Enter any drugstore or bookstore, and we confronted with a mountain of nonsense concerning the aging process. Society seems obsessed with aging. That is why The Death of Death is such a refreshing delight, able to cut through the hype and reveal a balanced, authoritative, and lucid discussion of this controversial topic. It summarizes the astonishing breakthroughs made recently in revealing how science may one day conquer the aging process. Michio Kaku, theoretical physicist and author of The God Equation: The Quest for a Theory of Everything We are entering a Fantastic Voyage into life extension, crossing different bridges that will take us to indefinite life spans. The Death of Death explains clearly how we might soon reach longevity escape velocity and live long enough to live forever. Ray Kurzweil, co-author of Fantastic Voyage: Live Long Enough to Live Forever and co-founder of Singularity University The Death of Death is a truly revolutionary book. This is a visionary book that confronts us with the terrible reality of aging, and its authors are friends and connoisseurs of the subject. I believe that the authoritative and exhaustive description of this crusade that José and David make in this excellent book will accelerate this process. Forward! Aubrey de Grey, founder of LEV (Longevity Escape Velocity) Foundation and co-author of Ending Aging
The Brontës of Haworth: Yorkshire's Literary Giants - Their Lives, Works, Influences and Inspirations has been designed by a retired teacher of English as a general, overall guide and reference for use by highschool teachers, college and university professors, students and Brontë enthusiasts The functional layout of the book in three parts allows readers and researchers to obtain a quick, thumbnail sketch of the lives of each of the Brontës, each of their seven major adult works, and the various influence and inspirations which affected their short, tragic lives and led them into careers in writing. Each chapter in each section has been designed so that the brief background sketches of their lives and works can be read as an entity in itself, and from there, readers can choose which area they would like to pursue further through additional studies and research. The amount of research material on the Brontës is overwhelming, and it was the author's intention to briefly sort out various areas of potential interest for those just being introduced to this great family of English writers.
Within the Italian city states of the fifteenth and sixteenth centuries, a relatively high degree of mutual tolerance and tranquility existed between the enlightened Christian majority and the small Jewish minority. With the prevalence of favorable political, social, and economic circumstances for Jewish life in Italy, a considerable number of Jews participated freely in Renaissance culture while upholding an intense awareness of their own particular identity. This work is a study of the life and thought of one such Jew, Abraham b. Mordecai Farissol (1452-ca. 1528). While born in Avignon, Farissol spent most of his life in Italy close to the cultural centers of Renaissance society, primarily in Ferrara, but also in Mantua, Florence, and other Italian cities. As scribe, educator, cantor, communal leader, polemicist, Biblical exegete, and geographer, Farissol developed variegated interests and associations which provide exciting vantage points from which to view his cultural and social world. As one of the first comprehensive studies of any Italian Jewish figure of the period, this book represents an important contribution to an understanding of Jewish society and culture. But the significance of this study of Farissol's life extends beyond what can be learned about the man and his immediate community of co-religionists. Utilizing the life and thought of one person, it explores and explicates the dialogue between Judaism and the culture of the Italian Renaissance. Despite its intrinsic interest, Jewish intellectual history in the Renaissance has remained an underdeveloped field. Many sources still remain unexamined; monographs on specific themes and figures have yet to be written. David Ruderman's study breaks new ground by making use of extensive, yet previously unpublished sources on Farissol and his society and by integrating them into the broader context of Jewish and Renaissance culture. The work is of particular interest to historians of the Jews and of Renaissance Italy. It also offers the general reader an excellent case study of the symbiotic relationship between Western culture and its Jewish minority in one of the most fertile periods of European civilization. In dramatic fashion it illustrates how Jews not only survived but creatively flourished in a pluralistic setting by appropriating from the outside new forms and ideas which they integrated into their own vital cultural experience.
As Americans, liberty is an inalienable right that is granted to us by God, protected by the Constitution, and upheld by our government. Yet, Barack Obama doesn’t seem to share that view. To him, liberty is a threat to the government’s power and something to be squashed by any means possible, as bestselling author David Limbaugh shows to devastating affect in his new book, Crimes Against Liberty. Laying out his case like he would a criminal complaint, Limbaugh presents the evidence—count-by-count—against Obama. From exploiting the financial crisis for political gain, to restricting our personal freedoms through invasive healthcare and “green” policies, to endangering America with his feckless diplomacy and reckless dismantlement of our national security systems, Limbaugh proves—beyond a reasonable doubt—that Obama is guilty of crimes against liberty.
In this pioneering and original book, Anthony Seldon and David Walsh study the impact that the public schools had on the conduct of the Great War, and vice versa. Drawing on fresh evidence from 200 leading public schools and other archives, they challenge the conventional wisdom that it was the public school ethos that caused needless suffering on the Western Front and elsewhere. They distinguish between the younger front-line officers with recent school experience and the older 'top brass' whose mental outlook was shaped more by military background than by memories of school.??The Authors argue that, in general, the young officers' public school education imbued them with idealism, stoicism and a sense of service. While this helped them care selflessly for the men under their command in conditions of extreme danger, it resulted in their death rate being nearly twice the national average.??This poignant and thought-provoking work covers not just those who made the final sacrifice, but also those who returned, and?whose lives were shattered as a result of their physical and psychological wounds. It contains a wealth of unpublished detail about public school life before and during the War, and how these establishments and the country at large coped with the devastating loss of so many of the brightest and best. Seldon and Walsh conclude that, 100 years on, public school values and character training, far from being concepts to be mocked, remain relevant and that the present generation would benefit from studying them and the example of their predecessors.??Those who read Public Schools and the Great War will have their prevailing assumptions about the role and image of public schools, as popularised in Blackadder, challenged and perhaps changed.
Responsible Conduct of Research provides an overview of ethical, legal, and social issues in scientific research for science students, trainees and professional scientists. Written by two leading scholars in the field of research ethics, one with a background in natural science and the other with a background in philosophy and law, the book incorporates insights from these diverse disciplines throughout the text. The book provides in-depth analyses of a wide array of topics, including ethical theory and decision-making, misconduct, questionable research practices, research record-keeping, data sharing, data auditing, reproducibility, authorship, publication, peer review, intellectual property, conflict of interest, mentoring, safe research environment, animal experimentation, research with human subjects, and social responsibility. The book also includes interesting case studies and provocative questions at the end of each chapter that can serve as a basis for further analysis and discussion. The concluding chapter of the book describes some steps that researchers, institutional officials, government agencies, and scientific organizations can take to promote ethical conduct in scientific research. The 4th edition of Responsible Conduct of Research includes updated references and discussions of new and evolving topics, such as digital image manipulation, self-plagiarism, retractions, publication on pre-print servers, harassment, research with human biological samples, revisions to the Common Rule for research with human subjects, dual use research, the COVID-19 pandemic, providing science advise, and interactions with the media"--
Interesting and important ethical questions confront researchers, regulators, institutional review boards, support personnel, and research participants committed to the ethical conduct of human subjects research at all stages of research. Questions encompass - but are not limited to - study design, enrolling participants, balancing the clinical needs of participants against the research agenda, ending trials, discharging post-trial obligations, and resolving conflicts. Straightforward solutions to these types of questions are often not found in regulations, ethics codes, or the bioethics literature. These resources may leave room for interpretation, offer conflicting guidance, or simply fail to address particular questions. Ethics consultation, which has been offered in clinical care settings with regularity since the 1980s, has since the turn of the century increasingly been sought in the clinical research context. Because there has only lately been recognition that ethics consultants can play a valuable role helping the research community conduct research in the most ethically informed way, there are many open questions in the field of research ethics consultation including the appropriate role of consultants and the best methods of consultation. The Clinical Center Bioethics Consultation Service has been serving the NIH community of researchers, administrators, healthcare providers, and research participants for more than a decade, conducting nearly 1,000 consultations in that time. In this book, members of the Bioethics Consultation Service reflect on this long track-record and unparalleled range of research ethics consultations to share a collection of their most interesting and informative research ethics consultations and to start a dialogue on remaining open questions. Although the NIH experience is unique, this book focuses on cases - and associated lessons - that are generalizable and valuable for the entire clinical research community. This book will be valuable to ethics consultants, clinical investigators, students and teachers, and others desiring insight into clinical research ethics and ethics consultation.
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