Every day companies leave billions of dollars in invisible, unrealized savings on the table because of poor supply chain management practices. Now supply management experts Dave Nelson, Patricia E. Moody, and Jonathan Stegner show not only how leading companies recoup these savings through their mastery of target costing, value engineering, and supplier development, but how supply chain management -- the discipline of acquiring and moving material -- has become a manufacturing company's hottest competitive weapon. Based on a survey of 247 purchasing managers and more than 1,000 hours of interviews and on-site visits, the authors have selected ten top firms whose supply management pioneers excel at twenty "best practices." With cases and stories, Nelson, Moody, and Stegner show how these leading-edge purchasing departments at American Express, SmithKline Beecham, DaimlerChrysler, Harley-Davidson, Honda of America, IBM, John Deere, Whirlpool, Flextronics, and Sun Microsystems have put into place pathbreaking processes and procedures. Here, for example, described in step-by-step detail, are Chrysler's SCORE program and Honda's strategic sourcing strategy that saved the companies billions. The book also includes a crucial section on the next stage of supplier development that will involve the sourcing and allocation of ideas as well as materials. The authors provide concrete, practical steps to improvement that any supply chain manager can take to successfully implement these best practices. The Purchasing Machine will be required reading for logistics, purchasing, and procurement managers in hundreds of thousands of companies. The authoritative nature of the authors' source material is certain to make this the single most important and practical reference on best purchasing practices for years to come.
Induction of drug (xenobiotic)-metabolizing enzymes is a common biological response to xenobiotics, the mechanisms and consequences of which are important in academic, industrial, and regulatory areas of pharmacology and toxicology. This monograph, for the first time, has brought together researchers who deal specifically with drug-metabolizing enzymes and peroxisome proliferators. It contains an up-to-date review of peroxisome proliferation, with detailed tables on the 100 known peroxisome proliferators and studies on their hepatocarcinogic capacity. It provides current material from 12 different laboratories doing cutting-edge research on the effect of peroxisome proliferators on drug-metabolizing enzymes.The book covers the response of cytochrome P450s, UDP-glucuronosyltransferases, epoxide hydrolases, glutathione S-transferase, DT-diaphorase, and other enzymes.
A HIGH PERFORMANCE STRATEGY DEVELOPMENT PROCESS FOR MID-TIER COMPANIES Luck is not enough. You can create your future with radical thinking and a high performance process. Good processes will produce predictable results in terms of quality, innovation, performance and strategy. Superior processes will raise the bar even higher. Poor processes will reduce results significantly. The strategic processes currently available to small and medium sized businesses were designed for large corporations. They are driven by intense analytics. Their goal is to protect and optimize what already exists. This does not match the needs or the resources of mid-tier companies. This book proposes a high performance strategic planning process for small and mid-sized firms. It starts from the premise that 60 to 80% of the information required to formulate strategy is already present inside the organizaation. Generally, that is sufficent. The challenge is to design a process and develop specific tools or methodologies that are aligned to this approach for mid-tier comanies. Such tools, validated by solid field experience, are presented in the book as well as the culture and the mindset that are required to apply them successfully.
The idea of covenant was at the heart of early New England society. In this singular book David Weir explores the origins and development of covenant thought in America by analyzing the town and church documents written and signed by seventeenth-century New Englanders. Unmatched in the breadth of its scope, this study takes into account all of the surviving covenants in all of the New England colonies. Weir's comprehensive survey of seventeenth-century covenants leads to a more complex picture of early New England than what emerges from looking at only a few famous civil covenants like the Mayflower Compact. His work shows covenant theology being transformed into a covenantal vision for society but also reveals the stress and strains on church-state relationships that eventually led to more secularized colonial governments in eighteenth-century New England. He concludes that New England colonial society was much more "English" and much less "American" than has often been thought, and that the New England colonies substantially mirrored religious and social change in Old England.
THE TRUTH ABOUT THE BLACK LIVES MATTER MARTYRS “This book is essential. Don’t miss it.” —MARK LEVIN “A brilliant examination of the actual facts of the George Floyd case and the subsequent exploitation of his death by Black Lives Matter.” —LEO TERRELL, civil rights attorney & commentator In his latest salvo in the battle for America’s survival, David Horowitz exposes the racial hoax that is spawning riots and dividing the nation. Examining the twenty-six most notorious cases of police “racism”— from Trayvon Martin and Michael Brown to George Floyd and Breonna Taylor—Horowitz demonstrates that Black Lives Matter has lied about every one of them in its quest to undermine law and order, fuel race hatred, and destroy America. In case after case, the lies and mythmaking break down under Horowitz’s scrutiny. Even the chief prosecutor in the George Floyd case was forced to admit that he had no evidence of racial bias, while Breonna Taylor, the longtime accomplice of a major drug dealer, was killed when she and her boyfriend resisted arrest. The unchallenged myths about racist murders by the police have brought mayhem and crime to our cities, where the victims are predominantly black. They are also a slander against the United States, the least racist country in history, and against black Americans, the vast majority of whom are successful and law-abiding citizens. Now the Biden administration has embraced the false narrative of “systemic racism” and “white supremacy,” which supposedly infect every aspect of American life, using it to justify a witch hunt for “domestic terrorists.” Most Americans, black and white, know in their bones that this portrayal of their country is a lie. An unflinching and courageous accounting, I Can’t Breathe is the urgently needed proof that they are right.
The right to keep and bear arms evokes great controversy. To some, it is a bulwark against tyranny and criminal violence; to others, it is an anachronism and serious danger.Firearms Law and the Second Amendment is the leading casebook and scholarly treatise on arms law. It provides a comprehensive domestic and international treatment of the history of arms law. In-depth coverage of modern federal and state laws and litigation prepare students to be practice-ready for firearms cases. The book covers legal history from ninth-century England through the United States in 2021. It examines arms laws and culture in broad social context, ranging from racial issues to technological advances. Seven online chapters cover arms laws in global historical context, from Confucian times to the present. The online chapters also discuss arms law and policy relating to race, gender, sexual orientation, and other statuses and how firearms and ammunition work. New to the Third Edition: Important cases and new regulatory issues since the 2017 second edition, including public carry, limits on in-home possession, bans on types of arms, non-firearm arms (like knives or sprays), Red Flag laws, and restoration of firearms rights Expanded social science and criminological data about firearms ownership and crimes Deeper coverage of state arms control laws and constitutional provisions Extended analysis of how Native American firearm policies and skills shaped interactions with European-Americans, provided the tools for three centuries of resistance, and became a foundation of American arms culture The latest research on English legal history, which is essential to modern cases on the right to bear arms Professors, students, and practicing lawyers will benefit from: Practical advice and resource guides for lawyers, like early career prosecutors or defenders, who will soon practice firearms law Five chapters on the diverse approaches of lower courts in applying the Supreme Court precedents in Heller and McDonald to contemporary laws Historical sources that shaped, and continue to influence, the right to arms
This series provides an unequalled source of information on an area of chemistry that continues to grow in importance. Divided into sections mainly according to the particular spectroscopic technique used, coverage in each volume includes: NMR (with reference to stereochemistry, dynamic systems, paramagnetic complexes, solid state NMR and Groups 13-18); nuclear quadrupole resonance spectroscopy; vibrational spectroscopy of main group and transition element compounds and coordinated ligands; and electron diffraction. Reflecting the growing volume of published work in the field, researchers will find this an invaluable source of information on current methods and applications. Volume 39 provides a critical review of the literature published up to late 2004.
The first edition, published in 1973, has become a classicreference in the field. Now with the second edition, readers willfind information on key new topics such as neural networks andstatistical pattern recognition, the theory of machine learning,and the theory of invariances. Also included are worked examples,comparisons between different methods, extensive graphics, expandedexercises and computer project topics. An Instructor's Manual presenting detailed solutions to all theproblems in the book is available from the Wiley editorialdepartment.
The nine colleges of colonial America confronted the major political currents of the seventeenth and eighteenth centuries, while serving as the primary intellectual institutions for Puritanism and the transition to Enlightenment thought. The colleges also confronted the most partisan and divisive cultural movement of the eighteenth century--the Great Awakening. Creating the American Mind is the first book to present a synthetic treatment of the colonial colleges, tracing their role in the intellectual development of early Americans through the Revolution. Distinguished historian J. David Hoeveler focuses on Harvard, William and Mary, Yale, the College of New Jersey (Princeton), King's College (Columbia), the College of Philadelphia (University of Pennsylvania), Queen's College (Rutgers), the College of Rhode Island (Brown), and Dartmouth. Hoeveler pays special attention to the collegiate experience of prominent Americans, including Jefferson, Hamilton, and Madison. Written in clear and engaging prose, Creating the American Mind will be of great value to historians and educators interested in rediscovering the institutions that first fostered American intellectual thought.
A single source of much of the information that doctors and other health care workers need in order to learn if a birth defect or genetic condition can be diagnosed prenatally." -- American Journal of Human Genetics
Organized by application areas, rather than by specific network architectures or learning algorithms, Building Neural Networks shows why certain networks are more suitable than others for solving specific kinds of problems. Skapura also reviews principles of neural information processing and furnishes an operations summary of the most popular neural-network processing models.
Distinguished by the critical value it assigns to law in Puritan society, this study describes precisely how the Massachusetts legal system differed from England's and how equity and an adapted common law became so useful to ordinary individuals. The author discovers that law gradually replaced religion and communalism as the source of social stability, and he gives a new interpretation to the witchcraft prosecutions of 1692. Originally published 1979. A UNC Press Enduring Edition -- UNC Press Enduring Editions use the latest in digital technology to make available again books from our distinguished backlist that were previously out of print. These editions are published unaltered from the original, and are presented in affordable paperback formats, bringing readers both historical and cultural value.
Presents a comprehensive introduction to the selection,operation, and testing of infrared devices, including adescription of modern detector assemblies and theiroperation This book discusses how to use and test infrared and visibledetectors. The book provides a convenient reference for thoseentering the field of IR detector design, test or use, those whowork in the peripheral areas, and those who teach and train othersin the field. Chapter 1 contains introductory material. Radiometry is coveredin Chapter 2. The author examines Thermal detectors in Chapter 3;the “Classical” photon detectors – simplephotoconductors and photovoltaics in Chapter 4; and “ModernPhoton Detectors” in Chapter 5. Chapters 6 through 8consider respectively individual elements and small arrays ofelements the “readouts” (ROICs) used with large imagingarrays; and Electronics for FPA Operation and Testing. The Test Setand The Testing Process are analyzed in Chapters 9 and 10, withemphasis on uncertainty and trouble shooting. Chapters 11 through15 discuss related skills, such as Uncertainty, Cryogenics, Vacuum,Optics, and the use of Fourier Transforms in the detector business.Some highlights of this new edition are that it Discusses radiometric nomenclature and calculations, detectormechanisms, the associated electronics, how these devices aretested, and real-life effects and problems Examines new tools in Infrared detector operations,specifically: selection and use of ROICs, electronics for FPAoperation, operation of single element and very small FPAs,microbolometers, and multi-color FPAs Contains five chapters with frequently sought-after informationon related subjects, such as uncertainty, optics, cryogenics,vacuum, and the use of Fourier mathematics for detectoranalyses Fundamentals of Infrared and Visible Detector Operation andTesting, Second Edition, provides the background and vocabularynecessary to help readers understand the selection, operation, andtesting of modern infrared devices.
Annotation. Offers annotated references to some 800 recent publications on this African country, in sections on economy, ethnic groups, mass media, religion, banking, and science and technology. Includes a chronology, and an introductory essay providing background on Nigeria's history and contemporary issues. This revised bibliography updates the first edition, which was published in 1989. Annotation copyrighted by Book News, Inc., Portland, OR.
SUPPLY CHAIN MANAGEMENT BEST PRACTICES Although the fundamentals of the supply chain industry remain constant, massive shifts in the demands of the marketplace and powerful new technologies have changed the way supply chain and transportation companies must engage with and deliver solutions to their clients. In the newly revised Third Edition of Supply Chain Management Best Practices, noted journalist and supply chain expert David Blanchard delivers a compelling and comprehensive overview of the new technologies shaping the transportation and supply chain industries today and the processes that will transform them tomorrow. You’ll discover a thorough introduction to supply chain management, along with examples of best-in-class supply chains in a variety of industries. You’ll also find proven methods and KPIs for measuring the performance of a supply chain. The author presents the traditional core processes of supply chain management and discusses the techniques used by individual and trendsetting companies from around the world. Finally, you’ll learn about the strategies, solutions, and technologies used by leading companies to design their global organizations. From drones and the Internet of Things to same-day delivery, omni-channel distribution, artificial intelligence, Uber-style freight transportation apps, blockchain, and robotics, the book discusses how the transfer of computing power from central mainframes into smartphones and cloud-based services has enabled game-changing technologies to reach companies of all shapes and sizes. Perfect for supply chain managers and professionals, chief financial officers, chief information officers, and controllers, Supply Chain Management Best Practices will also earn a place in the libraries of manufacturing, warehouse, and purchasing managers who seek a one-stop resource to help them understand the latest trends and the enduring foundations of the supply chain industry. BUILD BEST-IN-CLASS SUPPLY CHAIN CAPABILITIES IN YOUR ORGANIZATION WITH THIS NEWLY UPDATED RESOURCE FROM AN INDUSTRY LEADER The revised and updated Third Edition of Supply Chain Management Best Practices offers readers an insightful and comprehensive take on the concepts, processes, and technologies that define today’s supply chain and transportation industries. You’ll discover must-know information about traditional and core processes, as well as new technologies like drones, the Internet of Things, same-day delivery, and artificial intelligence that are transforming the industry. The book contains valuable case studies, stories, and recent examples from real organizations implementing exciting new supply chain initiatives that are changing the way professionals think about their field. You’ll find proven methods for measuring the performance of supply chains and insights into the strategies, solutions, and technologies used by trendsetting companies across the world. Finally, you’ll learn why the transfer of computing power from central mainframes to the cloud and handheld devices has fundamentally changed the supply chain industry. Ideal for executives, controllers, supply chain managers and professionals, as well as manufacturing, warehouse, and purchasing managers, the Third Edition of Supply Chain Management Best Practices remains an indispensable resource for anyone seeking to maintain and optimize a supply chain that functions as a competitive advantage.
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