This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available.Key Features* Chapter on the study of bioenergetics of mitochondria in the intact cell* Appendix listing protein structure resources* Additional colour plates of protein structures* Many newly drawn illustrations* Website
The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.
Using detailed, empirical examples, Structural Equation Modeling, Second Edition, presents a thorough and sophisticated treatment of the foundations of structural equation modeling (SEM). It also demonstrates how SEM can provide a unique lens on the problems social and behavioral scientists face. Intended Audience While the book assumes some knowledge and background in statistics, it guides readers through the foundations and critical assumptions of SEM in an easy-to-understand manner.
Written from an engineering standpoint, this book provides the theoretical background and physical insight needed to understand new and future developments in the modeling and design of n- and p-MOS nanoscale transistors. A wealth of applications, illustrations and examples connect the methods described to all the latest issues in nanoscale MOSFET design. Key areas covered include: • Transport in arbitrary crystal orientations and strain conditions, and new channel and gate stack materials • All the relevant transport regimes, ranging from low field mobility to quasi-ballistic transport, described using a single modeling framework • Predictive capabilities of device models, discussed with systematic comparisons to experimental results
Hannah Arendt's work inspires many to stand in solidarity against authoritarianism, racial or gender-based violence, climate change, and right-wing populism. But what if a careful analysis of her oeuvre reveals a darker side to this intellectual legacy? What if solidarity, as she conceives of it, is not oriented toward equality, freedom, or justice for all, but creates a barrier to intersectional coalition building? In Arendt's Solidarity, David D. Kim illuminates Arendt's lifelong struggle with this deceptively straightforward yet divisive concept. Drawing upon her publications, unpublished documents, private letters, radio and television interviews, newspaper clippings, and archival marginalia, Kim examines how Arendt refutes solidarity as an effective political force against anti-Semitism, racial injustice, or social inequality. As Kim reveals, this conceptual conundrum follows the arc of Arendt's forced migration across the Atlantic and is directly related to every major concern of hers: Christian neighborly love, friendship, Jewish assimilation, Zionism, National Socialism, the American republic, Black Power, revolution, violence, and the human world. Kim places these thoughts in dialogue with dissenting voices, such as Thomas Mann, Gershom Scholem, Jean-Paul Sartre, James Baldwin, Frantz Fanon, James Forman, and Ralph Ellison. The result is a full-scale reinterpretation of Arendt's oeuvre.
Cosmopolitan Parables explores the global rise of the heavily debated concept of cosmopolitanism from a unique German literary perspective. Since the early 1990s, the notion of cosmopolitanism has acquired a new salience because of an alarming rise in nationalism, xenophobia, migration, international war, and genocide. This upsurge has transformed how artists and scholars worldwide assess the power of international civil society and its moral obligation to unite regardless of cultural background, religious affiliation, or national citizenship. It rejuvenates an ancient yet timely framework within which contemporary political crises are to be overcome, especially after the collapse of communist states and the intersection of postwar and postcolonial trajectories. To exemplify this global challenge, Kim examines three internationally acclaimed writers of German origin—Hans Christoph Buch, Michael Krüger, and W. G. Sebald—joined by their own harrowing experiences and stunning entanglements with Holocaust memory, postcolonial responsibility, and communist legacy. This bold new study is the first of its kind, interrogating transnational memories of trauma alongside globally shared responsibilities for justice. More important, it addresses the question of remembrance—whether the colonial past or the postwar legacy serves as a proper foundation upon which cosmopolitanism is to be pursued in today's era of globalization.
The book begins with a summary of the psychopathology of OCD as well as a critical explication of the phenomenology of obsessions and compulsions.The first part of the book provides a working knowledge of the psychopathology of the disorder, as well as the theoretical and empirical basis of the cognitive and behavioral approach to OCD. The second part of the book updates the reader on current OCD theory and research, including ERP. The third part of the book offers detailed, practical, step-by-step instruction on how to conduct CBT for OCD. The final section consists of four new chapters of OCD symptom subtypes"--
The fourth in the readers' series Resources for the Knowledge-Based Economy, The Strategic Management of Intellectual Capital analyzes the link between the strategic and operational roles of intellectual capital in the organization. The Strategic Management of Intellectual Capital is the perfect resource for the growing number of companies pursuing a strategic approach to managing their intellectual capital and harnessing and leveraging their knowledge, experience, and expertise more systematically to attain a competitive advantage.
Liquid Crystal Display Drivers deals with Liquid Crystal Displays from the electronic engineering point of view and is the first expressively focused on their driving circuits. After introducing the physical-chemical properties of the LC substances, their evolution and application to LCDs, the book converges to the examination and in-depth explanation of those reliable techniques, architectures, and design solutions amenable to efficiently design drivers for passive-matrix and active-matrix LCDs, both for small size and large size panels. Practical approaches regularly adopted for mass production but also emerging ones are discussed. The topics treated have in many cases general validity and found application also in alternative display technologies (OLEDs, Electrophoretic Displays, etc.).
This book is the first, single-source guide to successful experiments using the local electrode atom probe (LEAP®) microscope. Coverage is both comprehensive and user friendly, including the fundamentals of preparing specimens for the microscope from a variety of materials, the details of the instrumentation used in data collection, the parameters under which optimal data are collected, the current methods of data reconstruction, and selected methods of data analysis. Tricks of the trade are described that are often learned only through trial and error, allowing users to succeed much more quickly in the challenging areas of specimen preparation and data collection. A closing chapter on applications presents selected, state-of-the-art results using the LEAP microscope.
Events such as the 2004 Indian Ocean Tsunami, Hurricane Katrina in 2005 and the Japanese earthquakes and tsunamis in 2011 have provided unfortunate reminders of the susceptibility of many communities to devastating losses from natural hazards. These events provided graphic illustrations of how extreme hazard events adversely impact on people, affect communities and disrupt the community and societal mechanisms that serve to organize and sustain community capacities and functions. However, there is much that communities can do to mitigate their risk and manage disaster consequences. The construct that epitomizes how this is done is resilience. The contents of this volume provide valuable insights into how societal resilience can be developed and sustained. This considerably expanded new edition presents major topics of: Coexisting with Natural Hazards; Urban Resilience in Asia; Lifelines and Urban Resilience; Business Continuity in Disaster; Hazard Mitigation in Communities; Hazard Readiness and Resilience; Child Citizenship in Disaster Risk; Old Age and Resilience; Gender and Disaster Resilience; Impact of High Functionality on Resilience; Art and Resilience; Cross-Cultural Perspectives and Coping with Hazards; Religious Practices and Resilience; Living in Harmony with our Environment; Critical Incidence Response; Governance; Heat Wave Resilience; Wildfire Disaster Resilience; and Progress and Challenges to Disaster Risk Reduction and Resilience. This exceptional book brings together contributions from international experts in core areas and includes chapters that provide and overarching framework within which the need for interrelationships between levels to be developed is discussed. The book will be an outstanding resource for those researching or teaching courses in emergency management, disaster management, community development, environmental planning and urban development. In addition, it will serve law enforcement and emergency agencies, welfare agencies, and professionals in applied psychology.
Next Generation Mobile Broadcasting provides an overview of the past, present, and future of mobile multimedia broadcasting. The first part of the book—Mobile Broadcasting Worldwide—summarizes next-generation mobile broadcasting technologies currently available. This part covers the evolutions of the Japanese mobile broadcasting standard ISDB-T One-Seg, ISDB-Tmm and ISDB-TSB; the evolution of the South Korean T-DMB mobile broadcasting technology AT-DMB; the American mobile broadcasting standard ATSC-M/H; the Chinese broadcasting technologies DTMB and CMMB; second-generation digital terrestrial TV European standard DVB-T2 and its mobile profile T2-Lite; and the multicast/broadcast extension of 4G LTE cellular standard E-MBMS. This part includes a chapter about a common broadcast specification of state-of-the-art 3GPP and DVB standards to provide a broadcast overlay optimized for mobile and operated in conjunction with a broadband unicast access. It also contains an overview chapter on a new High-Efficiency Video Coding (HEVC) standard that is expected to provide significantly improved coding efficiency compared to current MPEG-4 AVC video coding. The second part of the book—Next-Generation Handheld DVB Technology: DVB-NGH —describes the latest mobile broadcast technology known as Digital Video Broadcasting-Next-Generation Handheld (DVB-NGH), which is expected to significantly outperform all existing technologies in both capacity and coverage. DVB-NGH introduces new technological solutions that along with the high performance of DVB-T2 make DVB-NGH a powerful next-generation mobile multimedia broadcasting technology. In fact, DVB-NGH can be regarded as the first 3G broadcasting system because it allows for the possibility of using multiple input multiple output MIMO antenna schemes to overcome the Shannon limit of single antenna wireless communications. DVB-NGH also allows the deployment of an optional satellite component forming a hybrid terrestrial-satellite network topology to improve coverage in rural areas where the installation of terrestrial networks is economically unfeasible. Although the commercial deployment of DVB-NGH is nowadays unclear after its standardization, it will be a reference point for future generations of digital terrestrial television technologies. Edited by a member of the DVB-NGH standardization group, the book includes contributions from a number of standardization groups worldwide—including Digital Video Broadcasting (DVB) in Europe; Advanced Television Systems Committee (ATSC) in the US, Korea, Japan, and China; Third Generation Partnership Project (3GPP); and the Moving Picture Experts Group (MPEG).
A Complete Reference Covering the Latest Technology in Metal Cutting Tools, Processes, and Equipment Metal Cutting Theory and Practice, Third Edition shapes the future of material removal in new and lasting ways. Centered on metallic work materials and traditional chip-forming cutting methods, the book provides a physical understanding of conventional and high-speed machining processes applied to metallic work pieces, and serves as a basis for effective process design and troubleshooting. This latest edition of a well-known reference highlights recent developments, covers the latest research results, and reflects current areas of emphasis in industrial practice. Based on the authors’ extensive automotive production experience, it covers several structural changes, and includes an extensive review of computer aided engineering (CAE) methods for process analysis and design. Providing updated material throughout, it offers insight and understanding to engineers looking to design, operate, troubleshoot, and improve high quality, cost effective metal cutting operations. The book contains extensive up-to-date references to both scientific and trade literature, and provides a description of error mapping and compensation strategies for CNC machines based on recently issued international standards, and includes chapters on cutting fluids and gear machining. The authors also offer updated information on tooling grades and practices for machining compacted graphite iron, nickel alloys, and other hard-to-machine materials, as well as a full description of minimum quantity lubrication systems, tooling, and processing practices. In addition, updated topics include machine tool types and structures, cutting tool materials and coatings, cutting mechanics and temperatures, process simulation and analysis, and tool wear from both chemical and mechanical viewpoints. Comprised of 17 chapters, this detailed study: Describes the common machining operations used to produce specific shapes or surface characteristics Contains conventional and advanced cutting tool technologies Explains the properties and characteristics of tools which influence tool design or selection Clarifies the physical mechanisms which lead to tool failure and identifies general strategies for reducing failure rates and increasing tool life Includes common machinability criteria, tests, and indices Breaks down the economics of machining operations Offers an overview of the engineering aspects of MQL machining Summarizes gear machining and finishing methods for common gear types, and more Metal Cutting Theory and Practice, Third Edition emphasizes the physical understanding and analysis for robust process design, troubleshooting, and improvement, and aids manufacturing engineering professionals, and engineering students in manufacturing engineering and machining processes programs.
The concept of adiabatic electronic potential-energy surfaces, defined by the Born?Oppenheimer approximation, is fundamental to our thinking about chemical processes. Recent computational as well as experimental studies have produced ample evidence that the so-called conical intersections of electronic energy surfaces, predicted by von Neumann and Wigner in 1929, are the rule rather than the exception in polyatomic molecules. It is nowadays increasingly recognized that conical intersections play a key mechanistic role in chemical reaction dynamics. This volume provides an up-to-date overview of the multi-faceted research on the role of conical intersections in photochemistry and photobiology, including basic theoretical concepts, novel computational strategies as well as innovative experiments. The contents and discussions will be of value to advanced students and researchers in photochemistry, molecular spectroscopy and related areas.
When it comes to food, nature provides a wealth of delicious choices. But each one also supplies unique health benefits. Leading nutritionist David Grotto reveals a wealth of power foods, from apples to yogurt, and explains why • A handful of cherries before bed can help you sleep better • Hot peppers may fight skin cancer • Potatoes may reduce the risk of stroke • Grape juice may be as heart-healthy as red wine • Honey can help wounds heal faster Each entry features a history of a food’s origin, a list of therapeutic benefits, information on scientific research, tips for use and preparation, and an appetizing recipe from a leading chef or nutritionist. Prepare to awaken your taste buds, lose weight, and let the healing begin!
Bacterial Endotoxic Lipopolysaccharides provides an up-to-date, two-volume review of the latest information regarding bacterial lipopolysaccharide structure and activities. These volumes cover the biochemistry, pharmacology, and pathophysiologic properties of endotoxins. The volumes also thoroughly discuss the strengths and weaknesses of new therapies for septic shock that are based on an immunological attack on endotoxins and the cytokines induced by endotoxins. All scientists involved in endotoxin research, clinical infectious disease specialists, and medical students interested in the pathogenesis of septic shock will find Bacterial Endotoxic Lipopolysaccharides invaluable as a reference resource.
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.
David Knoke and Song Yang's Social Network Analysis, Third Edition provides a concise introduction to the concepts and tools of social network analysis. The authors convey key material while at the same time minimizing technical complexities. The examples are simple: sets of 5 or 6 entities such as individuals, positions in a hierarchy, political offices, and nation-states, and the relations between them include friendship, communication, supervision, donations, and trade. The new edition reflects developments and changes in practice over the past decade. The authors also describe important recent developments in network analysis, especially in the fifth chapter. Exponential random graph models (ERGMs) are a prime example: when the second edition was published, P* models were the recommended approach for this, but they have been replaced by ERGMs. Finally, throughout the volume, the authors comment on the challenges and opportunities offered by internet and social media data.
How scientists are unravelling one of the most tantalizing questions in paleontology Our understanding of dinosaur behavior has long been hampered by the inevitable lack of evidence from animals that went extinct more than sixty-five million years ago and whose daily behaviors are rarely reflected by the fossil record. Today, with the discovery of new specimens and the development of new and cutting-edge techniques, paleontologists are making major advances in reconstructing how dinosaurs lived and acted. Uncovering Dinosaur Behavior provides an unparalleled look at this emerging field of science, presenting the latest findings on dinosaur behavior and explaining how researchers interpret the often minimal and even conflicting information available to them. David Hone begins by introducing readers to the fundamentals of dinosaur biology, diversity, and evolution, and goes on to describe behaviors across the whole range of species and groups, from feeding and communication to reproduction, sociality, and combat. Speculation about dinosaur behavior goes back to the earliest scientific studies of these “terrible lizards.” Hone traces how pioneering science is opening a window into prehistoric life as never before, and discusses future directions of research in this thrilling and rapidly growing area of paleontology. Written by one of the world’s leading dinosaur experts and featuring accurate color recreations by paleoartist Gabriel Ugueto along with a wealth of photos and diagrams, Uncovering Dinosaur Behavior is a foundational work on the subject and an invaluable reference for anyone interested in these amazing creatures.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Emergency physicians assess and manage a wide variety of problems from patients presenting with a diversity of severities, ranging from mild to severe and life-threatening. They are expected to maintain their competency and expertise in areas where there is rapid knowledge change. Evidence-based Emergency Medicine is the first book of its kind in emergency medicine to tackle the problems practicing physicians encounter in the emergency setting using an evidence-based approach. It summarizes the published evidence available for the diagnosis and treatment of common emergency health care problems in adults. Each chapter contextualizes a topic area using a clinical vignette and generates a series of key clinically important diagnostic and treatment questions. By completing detailed reviews of diagnostic and treatment research, using evidence from systematic reviews, RCTs, and prospective observational studies, the authors provide conclusions and practical recommendations. Focusing primarily on diagnosis in areas where evidence for treatment is well accepted (e.g. DVTs), and treatment in other diseases where diagnosis is not complex (e.g. asthma), this text is written by leading emergency physicians at the forefront of evidence-based medicine. Evidence-based Emergency Medicine is ideal for emergency physicians and trainees, emergency department staff, and family physicians specialising in the acute care of medical and injured patients.
This Advanced Introduction is an accessible and critical review of the economic foundations of tourism. Taking a regional approach based in macro- and resource economics, David Marcouiller points to how the competitive aspect of tourism can be transformative to regional activity. Offering insight into the decision-making process among both private and public stakeholders, this book makes clear the increasing necessity of using sound planning principles and practice to shape tourism consumption and production.
Examines what we know about the relationship between organic chemicals and human disease Organic chemicals are everywhere: in the air we breathe, the water we drink, and the food we eat. They are also found in a myriad of common household and personal care products. Unfortunately, exposure to some organic chemicals can result in adverse health effects, from growth and developmental disorders to cancer and neurodegenerative diseases. This book examines how organic chemicals affect human health. It looks at the different diseases as well as how individual organ systems are affected by organic chemicals. Effects of Persistent and Bioactive Organic Pollutants on Human Health begins with an introductory chapter explaining why we should care about organic chemicals and their effect on human health. Next, the authors address such important topics as: Burden of cancer from organic chemicals Organic chemicals and obesity Effects of organic chemicals on the male reproductive system Organic chemicals and the immune system Intellectual developmental disability syndromes and organic chemicals Mental illness and exposure to organic chemicals The book ends with an assessment of how much human disease is caused by organic chemicals. Chapters have been contributed by leading international experts in public and environmental health and are based on the latest research findings. Readers will find that all of the contributions are clear and easy to comprehend, with extensive references for further investigation of individual topics. Effects of Persistent and Bioactive Organic Pollutants on Human Health is recommended for students and professionals in medicine as well as public and environmental health, bringing them fully up to date with what we know about the relationship between organic chemicals and human health.
Is the nation state under siege? A common answer is that globalization poses two fundamental threats to state sovereignty. The first concerns the unleashing of centrifugal and centripetal forces - such as increasing market integration and the activities of institutions like the IMF, World Bank, and WTO - that imperil state sovereignty from 'outside' the nation state. The second threat emanates from self-determination movements that jeopardize state sovereignty from 'inside'. Rigorously analyzing popular hypotheses on globalization's effect on state sovereignty from a broad social sciences perspective, the authors use empirical evidence to suggest that globalization's multilevel threats to state sovereignty have been overestimated. In most instances globalization is likely to generate pressure for increased government spending while only one form of market integration - foreign direct investment by multinational enterprises - appears to increase any feeling of economic insecurity. This volume will be invaluable to course instructors at both graduate and undergraduate levels, policy makers and members of the general public who are concerned about the effects of globalization on the nation-state.
Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.
In May 2006, The University of Utah hosted an NSF-funded minicourse on stochastic partial differential equations. The goal of this minicourse was to introduce graduate students and recent Ph.D.s to various modern topics in stochastic PDEs, and to bring together several experts whose research is centered on the interface between Gaussian analysis, stochastic analysis, and stochastic partial differential equations. This monograph contains an up-to-date compilation of many of those lectures. Particular emphasis is paid to showcasing central ideas and displaying some of the many deep connections between the mentioned disciplines, all the time keeping a realistic pace for the student of the subject.
Hospitality Marketing is an introductory textbook which shows readers how to apply the principles of marketing within the hospitality industry. The fourth edition contains examples and case studies exemplifying how ideas and concepts discussed within its chapters can be successfully applied to a real-life work situation, with an emphasis throughout on topical issues such as sustainable marketing, corporate social responsibility and relationship marketing. It also describes the impact that the Internet has had on both marketing and hospitality, using a variety of tools including a wide range of Internet learning activities. This fourth edition has been updated to include: New content on social media marketing, user-generated content, group-buying behaviour, franchising, internationalization, non-predictable factors affecting sales and marketing such as COVID-19, the role of marketing in creating a competitive advantage and the role of events and experiences in marketing New extensive exploration of the role of technology in marketing including the use of artificial intelligence, service robots and the metaverse to develop and deliver service and/or to measure customer experience Updated online resources including a PowerPoint deck, a test bank of questions and added links to YouTube and Instagram content New/updated international case studies including many more from Asian and African destinations This book is written specifically for students taking marketing modules within hospitality courses and is a valuable resource to promote learning.
Framboids may be the most astonishing and abundant natural features you've never heard of. These microscopic spherules of golden pyrite consist of thousands of even smaller microcrystals, often arranged in stunning geometric arrays. They are rarely more than twenty micrometers across, and often look like miniscule raspberries under the microscope. The formation of a framboid is the result of self-assembly of pyrite micro- and nano-crystals under the influence of surface forces. They can be found all around us in rocks of all ages and present-day sediments, soils, and natural waters. Our planet makes billions every second and has been doing so for most of recorded geologic time. As a result, there are more framboids on our planet than there are sand grains on Earth or stars in the observable universe. The microscopic size of framboids belies their importance to contemporary science. They help us better understand inorganic self-assembly and self-organization, and studying them illuminates Earth's evolutionary history. In this book, David Rickard explains what framboids are, how they are formed, and what we can learn from them. The book's thirteen chapters trace everything from their basic attributes and mineralogy to their biogeochemistry and paleoenvironmental significance. Rickard expands on the most updated research and recent developments in geology, chemistry, biology, materials science, biogeochemistry, mineralogy, and crystallography, making this a must-have guide for researchers.
Concise and portable, Braddom's Clinical Handbook of Physical Medicine and Rehabilitation, by Drs. David X. Cifu and Henry L. Lew, gives you dependable, up-to-date content in a handbook format ideally suited for use at the bedside or in outpatient clinics. This quick reference covers the everyday topics you need – assistive devices and orthoses, spasticity, pediatric, adult, and geriatric care, pain management, outcome measures, and much more – all derived from the most trusted name in the field of PM&R. - Reader-friendly format with succinct, templated chapters for ease of use. - Authoritative content derived from the #1 comprehensive reference in the field: Braddom's Physical Medicine and Rehabilitation. - An ideal resource for the entire rehabilitation team as a quick reference or study guide. - Highlights key concepts spanning the full spectrum of rehabilitation medicine to help optimize outcomes for patients with a range of chronic diseases, impairments, and disabilities. - Includes eSlides complied by internationally renowned experts to summarize key teaching points and clinical pearls.
Interest and research on regionalism has soared in the last decade. Local governments in metropolitan areas and civic organizations are increasingly engaged in cooperative and collaborative public policy efforts to solve problems that stretch across urban centers and their surrounding suburbs. Yet there remains scant attention in textbooks to the issues that arise in trying to address metropolitan governance. Governing Metropolitan Areas describes and analyzes structure to understand the how and why of regionalism in our global age. The book covers governmental institutions and their evolution to governance, but with a continual focus on institutions. David Hamilton provides the necessary comprehensive, in-depth description and analysis of how metropolitan areas and governments within metropolitan areas developed, efforts to restructure and combine local governments, and governance within the polycentric urban region. This second edition is a major revision to update the scholarship and current thinking on regional governance. While the text still provides background on the historical development and growth of urban areas and governments' efforts to accommodate the growth of metropolitan areas, this edition also focuses on current efforts to provide governance through cooperative and collaborative solutions. There is also now extended treatment of how regional governance outside the United States has evolved and how other countries are approaching regional governance.
This book contains the necessary knowledge and tools to incorporate nutrition into primary care practice. As a practical matter, this effort is led by a dedicated primary care physician with the help of motivated registered dietitians, nurses, psychologists, physical therapists, and office staff whether within a known practice or by referral to the community. It is essential that the nutrition prescription provided by the physician be as efficient as possible. While many team members have superior knowledge in the areas of nutrition, exercise, and psychology, the health practitioner remains the focus of patient confidence in a therapy plan. Therefore, the endorsement of the plan rather than the implementation of the plan is the most important task of the physician. This book proposes a significant change in attitude of primary health care providers in terms of the power of nutrition in prevention and treatment of common disease. It features detailed and referenced information on the role of nutrition in the most common conditions encountered in primary care practice. In the past, treatment focused primarily on drugs and surgery for the treatment of disease with nutrition as an afterthought. Advanced technologies and drugs are effective for the treatment of acute disease, but many of the most common diseases such as heart disease, diabetes, and cancer are not preventable with drugs and surgery. While there is mention of prevention of heart disease, this largely relates to the use of statins with some modest discussion of a healthy diet. Similarly, prevention of type 2 diabetes is the early introduction of metformin or intensive insulin therapy.
Thoroughly updated to reflect the latest advances and technologies, Braddom's Physical Medicine and Rehabilitation, 6th Edition, remains the market leader in the field of PM&R. For more than 20 years, this bestselling reference has been the go-to resource for the entire rehabilitation team, providing in-depth coverage of essential core principles along with the latest research, technologies, and procedures that enhance patient care and facilitate optimal return to function. In this edition, lead editor Dr. David X. Cifu and his team of expert associate editors and contributing authors employ a more succinct format that emphasizes need-to-know material, incorporating new key summary features, including high-yield information and study sheets for problem-based learning. - Focuses more heavily on rehabilitation, with case studies throughout and more comprehensive coverage of stroke evaluation, rehabilitation, and therapies. - Provides expanded information on key topics such as interventional pain management options, gait and prosthetics, USG, fluoroscopy, electrodiagnosis and more. - Features a new chapter on Occupational Medicine and Vocational Rehabilitation, plus enhanced coverage of the neurogenic bladder, rehabilitation and prosthetic restoration in upper limb amputation, and acute medical conditions including cardiac disease, medical frailty, and renal failure. - Discusses quality and outcome measures for medical rehabilitation, practical aspects of impairment rating and disability determination, integrative medicine in rehabilitation, and assistive technology. - Offers highly illustrated, templated chapters that are easy to navigate without sacrificing coverage of key topics. - Includes access to dozens of even more practical videos and hundreds of integrated self-assessment questions for more effective learning and retention. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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