Dr. Rubin has brought cognitive psychology into a wholly unprecedented dialogue with studies in oral tradition. The result is a truly new perspective on memory and the processes of oral tradition." --John Miles Foley, University of Missouri
Dr. Rubin has brought cognitive psychology into a wholly unprecedented dialogue with studies in oral tradition. The result is a truly new perspective on memory and the processes of oral tradition." --John Miles Foley, University of Missouri
A pathophysiologic model for Stage 4 DLK that challenges current dogma in refractive surgery and simultaneously refutes four (4) broadly held paradigms in Ophthalmology including: - The etiology and pathophysiology of DLK - The etiology and pathophysiology of CTK - The mechanism that defines control of interstitial fluid pressures in the cornea - The primary etiology and control of corneal biomechanics. The profoundly revolutionary concepts articulated in this textbook redefine nearly everything we 'know' about control of fluid dynamics and the biomechanical forces that shape in the cornea. This is particularly true with respect to understanding how and why the cornea responds to laser refractive surgery, collagen crosslinking and femtosecond laser photodisruption and the etiology of disorders such as keratoconus.
Endothelial cells are early targets of radiation injury. Because these cells are tissues easily damaged by radiation, if we can understand the causes of radiation injury, then normal cells can be well protected and tumors can be destroyed. The Radiation Biology of the Vascular Endothelium brings together expert reviews on the biology and radiobiology of the vasculature, with emphasis on the endothelial cell component of blood vessels. The book covers both the basic aspects of endothelial cell biology and the practical consequences of this for the oncologist, with special reference to the radiation oncologist. After reading The Radiation Biology of the Vascular Endothelium, no clinical or experimental oncologist should be able to ignore the intimate relationship between tumor and normal tissue cells and endothelial cells that form the barrier to, and are the bearers of, essential nutrient supplies.
From the bestselling author of Ecohouse, this fully revised edition of Adapting Buildings and Cities for Climate Change provides unique insights into how we can protect our buildings, cities, infra-structures and lifestyles against risks associated with extreme weather and related social, economic and energy events. Three new chapters present evidence of escalating rates of environmental change. The authors explore the growing urgency for mitigation and adaptation responses that deal with the resulting challenges. Theoretical information sits alongside practical design guidelines, so architects, designers and planners can not only see clearly what problems they face, but also find the solutions they need, in order to respond to power and water supply needs. Considers use of materials, structures, site issues and planning in order to provide design solutions. Examines recent climate events in the US and UK and looks at how architecture was successful or not in preventing building damage. Adapting Buildings and Cities for Climate Change is an essential source, not just for architects, engineers and planners facing the challenges of designing our building for a changing climate, but also for everyone involved in their production and use.
This book provides guidance to all professionals working with children who present with injuries, neglect, illness falsification and other forms of child abuse. Clinical findings and the current literature are analyzed. The author’s clinical experience is shared to assist the reader in diagnosing the cause of injury and other presentations. This text is the result of many years of experience in the UK working with children in an East London hospital (which receives over 1000 children a week through the children’s Emergency Department) and the analysis of over 400 cases for the Family and Crown Courts. Mainstream opinions, the medical literature, and examples from extensive experience on the wards and in Court are discussed. Pediatric Forensic Evidence is aimed at doctors, lawyers, the Courts, social workers, health visitors, teachers, the police and others, guiding them through the analysis of injury and when to raise concerns.
Examines what we know about the relationship between organic chemicals and human disease Organic chemicals are everywhere: in the air we breathe, the water we drink, and the food we eat. They are also found in a myriad of common household and personal care products. Unfortunately, exposure to some organic chemicals can result in adverse health effects, from growth and developmental disorders to cancer and neurodegenerative diseases. This book examines how organic chemicals affect human health. It looks at the different diseases as well as how individual organ systems are affected by organic chemicals. Effects of Persistent and Bioactive Organic Pollutants on Human Health begins with an introductory chapter explaining why we should care about organic chemicals and their effect on human health. Next, the authors address such important topics as: Burden of cancer from organic chemicals Organic chemicals and obesity Effects of organic chemicals on the male reproductive system Organic chemicals and the immune system Intellectual developmental disability syndromes and organic chemicals Mental illness and exposure to organic chemicals The book ends with an assessment of how much human disease is caused by organic chemicals. Chapters have been contributed by leading international experts in public and environmental health and are based on the latest research findings. Readers will find that all of the contributions are clear and easy to comprehend, with extensive references for further investigation of individual topics. Effects of Persistent and Bioactive Organic Pollutants on Human Health is recommended for students and professionals in medicine as well as public and environmental health, bringing them fully up to date with what we know about the relationship between organic chemicals and human health.
Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic scien
This chapter covers the chemistry of three-membered heterocycles, epoxides, aziridines, azirines, and oxaziridines for the calendar year 2012. For each of the different three-membered heterocycles, a listing of new methods of synthesis and new examples of reactions are presented. This review is not comprehensive for 2012 but covers methods and reactions that should be synthetically useful for the practicing chemist and those interested in the study of three-membered heterocyclic ring systems.
Looking beyond the communications technology horizon and projecting future competency-specific employment demand, this book presents an evaluation of desirable information systems enhancements by integrating two disparate-domain computer ontologies. It provides readers a fresh solutions approach based on dynamic modeling and methodological contributions to philosophical and assistive communications system development in healthcare, addressing the need for both demand intelligence and practical work environment support. The pace of change in redefining occupation-specific employee resourcing needs is unrelenting and continues to accelerate. And the exponential growth in the demand for healthcare service delivery is correspondingly daunting. As such, the public and private sectors are faced with the challenge of sustaining credible relevant demand intelligence and recruitment practices, while integration, expansion and enrichment of ostensibly unconnected ontologies represent key R&D issues.
Pediatric intensivists, cardiologists, cardiac surgeons, and anesthesiologists from the leading centers around the world present the collaborative perspectives, concepts, and state-of-the-art knowledge required to care for children with congenital and acquired heart disease in the ICU. Their multidisciplinary approach encompasses every aspect of the relevant basic scientific principles, medical and pharmacologic treatments, and surgical techniques and equipment. From the extracardiac Fontan procedure, and the Ross procedure through new pharmacologic agents and the treatment of pulmonary hypertension to mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization—all of the developments that are affecting this rapidly advancing field are covered in depth. Employs well-documented tables, text boxes, and algorithms to make clinical information easy to access. Features chapters each written and reviewed by intensivists, surgeons, and cardiologists. Integrates the authors' extensive experiences with state-of-the-art knowledge from the literature. Offers four completely new chapters: Cardiac Trauma, Congenital Heart Disease in the Adult, Congenitally Corrected Transposition of the Great Arteries, and Outcome Evaluation. Describes the basic pharmacology and clinical applications of all of the new pharmacologic agents. Details important refinements and developments in surgical techniques, including the Ross pulmonary autograft replacement of the aortic valve, video-assisted fluoroscopy, and the extracardiac Fontan connection, and discusses their indications and potential complications. Explores the latest advances in the treatment of pulmonary hypertension, new developments in mechanical assist devices, heart and lung transplantation, and interventional cardiac catheterization. Examines issues affecting adults with congenital heart disease.
The second edition of this comprehensive textbook for students of Neuropsychology gives a thorough overview of the complex relationship between brain and behaviour. With an excellent blend of clinical, experimental and theoretical coverage, it draws on the latest research findings from neuroscience, cognitive neuroscience, neurochemistry, clinical neuropsychology and neuropsychology to provide students with new insights in this fast moving field. The book is organised around the main neuropsychological disorders in the areas of perception, executive dysfunction, attention, memory, cerebral asymmetry, language, emotion and consciousness. There is a clear emphasis on bridging the gap between theory and practice with links throughout to clinical issues of both assessment and rehabilitation to build a clear understanding of the application of the theoretical issues. The final section in each chapter illustrates the importance of a more systematic approach to intervention, which takes into account theoretical views of recovery from brain damage. New to this edition: A new chapter format that includes a "basic topic" section, which contains up-to-date essential knowledge of the topic and a "further topics" section for a more advanced treatment of the area. A new section on neuroscientific approaches to rehabilitation in each chapter to make links between scientific knowledge and clinical treatment. A brand new chapter on consciousness A new full colour layout with increased pedagogical features, including key terms, section summaries, ‘study questions’ and improved presentation of figures and brain diagrams A companion website including related weblinks, guidance on answering the ‘study questions’, and flashcards. This book will be invaluable for undergraduate students in Neuropsychology and students who wish to take the subject further to the various clinical fields.
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A "who’s who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers.
Addressing a key social policy problem, this book analyses modern voluntary organisations through the lens of a new theory of hybrid organisations, which is tested and developed in the context of a range of case studies. Essential reading for all interested in the future of the third sector.
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
Winner of the 2016 De Groot Prize from the International Society for Bayesian AnalysisNow in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied
Of interest to historians, classicists, media and digital theorists, literary scholars, museologists, and archivists, Media, Memory, and the First World War is a comparative study that shows how the dominant mode of communication in a popular culture - from oral traditions to digital media - shapes the structure of memory within that culture.
An up-to-date, comprehensive account of major issues in finitemixture modeling This volume provides an up-to-date account of the theory andapplications of modeling via finite mixture distributions. With anemphasis on the applications of mixture models in both mainstreamanalysis and other areas such as unsupervised pattern recognition,speech recognition, and medical imaging, the book describes theformulations of the finite mixture approach, details itsmethodology, discusses aspects of its implementation, andillustrates its application in many common statisticalcontexts. Major issues discussed in this book include identifiabilityproblems, actual fitting of finite mixtures through use of the EMalgorithm, properties of the maximum likelihood estimators soobtained, assessment of the number of components to be used in themixture, and the applicability of asymptotic theory in providing abasis for the solutions to some of these problems. The author alsoconsiders how the EM algorithm can be scaled to handle the fittingof mixture models to very large databases, as in data miningapplications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and patternrecognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied andtheoretical statisticians as well as for researchers in the manyareas in which finite mixture models can be used to analyze data.
Examines just how the important goals of educating for democracy can be achieved from the perspective of those working in teacher education and in P-12 schools.
This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1888 edition. Excerpt: ...apparel and sought and obtained employment as a teamster in the quartermasters department. Her features were very large, and so coarse and masculine was her general appearance that she would readily have passed as a man, and in her case the deception was no doubt easily practiced. Next day the "she dragoon " was caught, and proved to be a rather prepossessing young woman, and though necessarily bronzed and hardened by exposure, I doubt if, even with these marks of campaigning, she could have deceived as readily as did her companion. How the two got acquainted I never learned, and though they had joined the army independently of each other, yet an intimacy had sprung up between them long before the mishaps of the foraging expedition. They both were forwarded to army headquarters, and, when provided with clothing suited to their sex, sent back to Nashville, and thence beyond our lines to Louisville. On January 9, by an order from the War Department, the Army of the Cumberland had been divided into three corps, designated the Fourteenth, Twentieth, and Twenty-first. This order did not alter the composition of the former grand divisions, nor change the commanders, but the new nomenclature was a decided improvement over the clumsy designations Right Wing, Centre, and Left Wing, which were well calculated to lead to confusion sometimes. McCooks wing became the Twentieth Corps, and my division continued of the same organization, and held the same number as formerly--the Third Division, Twentieth Corps. My first brigade was now commanded by Brigadier-General William H. Lytle, the second by Colonel Bernard Laiboldt, and the third by Colonel Luther P. Bradley. On the 4th of March I was directed to move in light marching order toward Franklin and...
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.