Computer-aided synthesis of digital circuits from behavioral level specifications offers an effective means to deal with increasing complexity of digital hardware design. High Level Synthesis of ASICs Under Timing and Synchronization Constraints addresses both theoretical and practical aspects in the design of a high-level synthesis system that transforms a behavioral level description of hardware to a synchronous logic-level implementation consisting of logic gates and registers. High Level Synthesis of ASICs Under Timing and Synchronization Constraints addresses specific issues in applying high-level synthesis techniques to the design of ASICs. This complements previous results achieved in synthesis of general-purpose and signal processors, where data-path design is of utmost importance. In contrast, ASIC designs are often characterized by complex control schemes, to support communication and synchronization with the environment. The combined design of efficient data-path control-unit is the major contribution of this book. Three requirements are important in modeling ASIC designs: concurrency, external synchronization, and detailed timing constraints. The objective of the research work presented here is to develop a hardware model incorporating these requirements as well as synthesis algorithms that operate on this hardware model. The contributions of this book address both the theory and the implementation of algorithm for hardware synthesis.
This book provides a comprehensive introduction to the theory of ordinary differential equations with a focus on mechanics and dynamical systems as important applications of the theory. The text is written to be used in the traditional way or in a more applied way. The accompanying CD contains Maple worksheets for the exercises, and special Maple code for performing various tasks. In addition to its use in a traditional one or two semester graduate course in mathematics, the book is organized to be used for interdisciplinary courses in applied mathematics, physics, and engineering.
Calixarenes was the first book to be published in the `Monographs in Supramolecular Chemistry' series and is also the first complete survey available of this rapidly developing field. It provides a fascinating and lively account of the history, development and applications of calixarenes, which are probably the world's most readily available synthetic molecular baskets. These basket shaped compounds possess the ability to hold metal ions, as well as molecules, in their interior and as a result of their extraordinarily easy synthesis from phenols and aldehydes are receiving increasingly wide attention. This book is a must for advanced undergraduates and post-graduates studying bio-organic and supramolecular chemistry.
This guide covers all aspects pertaining to the use of zebrafish including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. The zebrafish is now a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management. The new edition includes more figures, tables and bullet points, a wealth of new full-color images, major updates on health and welfare (including colony health surveillance and viruses), and a complete overhaul of the compliance section to address more international concerns.
The fifteen chapters of this book are arranged in a logical progression. The text begins with the more fundamental material on stress and strain transformations with elasticity theory for plane and axially symmetric bodies, followed by a full treatment of the theories of bending and torsion. Coverage of moment distribution, shear flow, struts and energy methods precede a chapter on finite elements. Thereafter, the book presents yield and strength criteria, plasticity, collapse, creep, visco-elasticity, fatigue and fracture mechanics. Appended is material on the properties of areas, matrices and stress concentrations. Each topic is illustrated by worked examples and supported by numerous exercises drawn from the author's teaching experience and professional institution examinations (CEI).This edition includes new material and an extended exercise section for each of the fifteen chapters, as well as three appendices. The broad text ensures its suitability for undergraduate and postgraduate courses in which the mechanics of solids and structures form a part including: mechanical, aeronautical, civil, design and materials engineering.
This volume is based on lectures on division algebras given at a conference held at Colorado State University. Although division algebras are a very classical object, this book presents this ""classical"" material in a new way, highlighting current approaches and new theorems, and illuminating the connections with a variety of areas in mathematics.
An accessible introduction to the practical aspects of satellite communications. Provides historical background of satellite communications and discusses the wide range of applications throughout the world. Includes descriptions of all the commercial satellite communications systems currently available and their applications in government, broadcasting, and business. Also covers the growing use of satellite communications by developing countries. Contains extensive appendices listing satellite equipment and organizations.
Calixarenes was the first book to be published in the `Monographs in Supramolecular Chemistry' series and is also the first complete survey available of this rapidly developing field. It provides a fascinating and lively account of the history, development and applications of calixarenes, which are probably the world's most readily available synthetic molecular baskets. These basket shaped compounds possess the ability to hold metal ions, as well as molecules, in their interior and as a result of their extraordinarily easy synthesis from phenols and aldehydes are receiving increasingly wide attention. This book is a must for advanced undergraduates and post-graduates studying bio-organic and supramolecular chemistry.
The book covers the research on economic inequality, including the social construction of racial categories, the uneven and stalled gender revolution, and the role of new educational forms and institutions in generating both equality and inequality.
Presents the concepts, technology, and role of satellite systems in support of personal applications, such as mobile and broadband communications, navigation, television, radio and multimedia broadcasting, safety of life services, etc. This book presents a novel perspective on satellite systems, reflecting the modern personal technology context, and hence a focus on the individual as end-user. The book begins by outlining key generic concepts before discussing techniques adopted in particular application areas; next, it exemplifies these techniques through discussion of state-of-art current and emerging satellite systems. The book concludes by contemplating the likely evolution of these systems, taking into consideration influences and trends in technology, in conjunction with growing user expectations. In addition to addressing satellite systems that directly interact with personal devices, the book additionally considers those indirect applications where there is an increasing interest by individuals - notably, in remote sensing. As such, the book uniquely encompasses the entire gamut of satellite-enabled personal / end-user applications. Key Features: Broad scope - views satellite systems generically with regards to their applicability across a wide range of personal application areas Strong foundation in underlying concepts State-of-the-art system examples Review of trends in relevant areas of satellite technology Revision questions at the end of each chapter The book is suited to individuals, engineers, scientists, service providers, system operators, application developers and managers interested or involved in the use of satellite technology for personal applications. It should also hold interest for use in research institutes interested in promoting inter-disciplinary cross-fertilization of ideas, as well as by financiers, policy makers, and strategists interested in gaining a better understanding of this technology.
In spite of the Challenger and Columbia disasters, the US Space Shuttle, which entered service in 1981, remains the most successful spacecraft ever developed. Conceived and designed as a reusable spacecraft to provide cheap access to low Earth orbit, and to supersede expendable launch vehicles, serving as the National Space Transportation System, it now coexists with a new range of commercial rockets. David Harland’s definitive work on the Space Shuttle explains the scientific contribution the Space Shuttle has made to the international space programme, detailing missions to Mir, Hubble and more recently its role in the assembly of the International Space Station. This substantial revision to existing chapters and extension of ‘The Space Shuttle’, following the loss of Columbia, will include a comprehensive account of the run-up to resumption of operations and conclude with a chapter beyond the Shuttle, looking at possible future concepts for a partly or totally reusable space vehicle which are being considered to replace the Shuttle.
The human urinary bladder is subject to a unique and extraordinarily diverse array of congenital, inflammatory, metaplastic, and neoplastic abnormalities. This book provides contemporary, comprehensive, and evidence-based practice information for pathologists, urologists, oncologists, and other medical professionals. In Bladder Pathology, a full spectrum of pathologic conditions that afflict the bladder and urothelium are described and lavishly illustrated. With its emphasis on diagnostic criteria and differential diagnoses, this book is of particular value to practicing pathologists—assisting in the pathologist’s recognition, understanding, and accurate interpretation of the light microscopic findings in bladder specimens. Features and benefits of this new volume include: • 1,741 high-quality, color illustrations and 112 tables to illustrate the wide range of pathologic and clinical features in the urinary tract • An evidence-based approach to diagnosis and patient management for infectious, nonneoplastic, and neoplastic conditions • Recent advances in the molecular genetics of the urinary bladder with discussion of their current or potential impact on diagnosis and personalized patient care • With emphasis on the scientific validation of current diagnostic methods and their direct application in clinical practice, Bladder Pathology is a cutting-edge resource that not only offers comprehensive research and clinical information for practicing surgical pathologists, urologists, oncologists, and their clinical colleagues, but also captures a genuine sense of excitement about recent advances in this vital, ever-evolving field.
This seminal work is the first fully to engage human security with power in the international system. It presents global governance not as impartial institutionalism, but as the calculated mismanagement of life, directing biopolitical neoliberal ideology through global networks, undermining the human security of millions. The book responds to recent critiques of the human security concept as incoherent by identifying and prioritizing transnational human populations facing life-ending contingencies en mass. Furthermore, it proposes a realignment of World Bank practices towards mobilizing indigenous provision of water and sanitation in areas with the highest rates of avoidable child mortality. Roberts demonstrates that mainstream IR's nihilistic domination of security thinking is directly responsible for blocking the realization of greater human security for countless people worldwide, whilst its assumptions and attendant policies perpetuate the dystopia its proponents claim is inevitable. Yet this book presents a viable means of achieving a form of human security so far denied to the most vulnerable people in the world.
Ideal text for undergraduate and graduate students in advanced cell biology courses Extraordinary technological advances in the last century have fundamentally altered the way we ask questions about biology, and undergraduate and graduate students must have the necessary tools to investigate the world of the cell. The ideal text for students in advanced cell biology courses, Lewin's CELLS, Third Edition continues to offer a comprehensive, rigorous overview of the structure, organization, growth, regulation, movements, and interactions of cells, with an emphasis on eukaryotic cells. The text provides students with a solid grounding in the concepts and mechanisms underlying cell structure and function, and will leave them with a firm foundation in cell biology as well as a "big picture" view of the world of the cell. Revised and updated to reflect the most recent research in cell biology, Lewin's CELLS, Third Edition includes expanded chapters on Nuclear Structure and Transport, Chromatin and Chromosomes, Apoptosis, Principles of Cell Signaling, The Extracellular Matrix and Cell Adhesion, Plant Cell Biology, and more. All-new design features and a chapter-by-chapter emphasis on key concepts enhance pedagogy and emphasize retention and application of new skills. Thorough, accessible, and essential, Lewin's CELLS, Third Edition, turns a new and sharper lens on the fundamental units of life
A long-awaited, updated introductory text by the world leaders in potential theory. This essential reference work covers all aspects of this major field of mathematical research, from basic theory and exercises to more advanced topological ideas. The largely self-contained presentation makes it basically accessible to graduate students.
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Profiling hundreds of space programmes and their different technologies, Jane's Space Directory enables you to identify thousands of different commercial and defence applications. Key objectives, developments and technical specifications of available vehicles and systems are reviewed, including the new generation of launch vehicles. Structured around the categorisation of functions and presented for quick comparison and evaluation, each entry comes with accompanying illustrations. Supplier and manufacturer listings help support your market research and procurement requirements. Key content includes: Government and non-government space programmes; Global space industry directory; Civilian operations; Orbital and suborbital launch vehicles; Propulsion; Commercial and military satellites; Planetary and space science; Human space flight; Launch listings; Contractors. For a complete listing of aerospace organisations and personnel around the globe see Jane's International ABC Aerospace Directory.
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you’ll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski’s Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need.
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you'll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski's Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. And, as an Expert Consult title, this thoroughly updated 7th edition comes with access to the complete contents online, fully searchable. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need. Provides access to the complete contents online, fully searchable, enabling you to consult it rapidly from any computer with an Internet connection. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Methods of solution for partial differential equations (PDEs) used in mathematics, science, and engineering are clarified in this self-contained source. The reader will learn how to use PDEs to predict system behaviour from an initial state of the system and from external influences, and enhance the success of endeavours involving reasonably smooth, predictable changes of measurable quantities. This text enables the reader to not only find solutions of many PDEs, but also to interpret and use these solutions. It offers 6000 exercises ranging from routine to challenging. The palatable, motivated proofs enhance understanding and retention of the material. Topics not usually found in books at this level include but examined in this text: the application of linear and nonlinear first-order PDEs to the evolution of population densities and to traffic shocks convergence of numerical solutions of PDEs and implementation on a computer convergence of Laplace series on spheres quantum mechanics of the hydrogen atom solving PDEs on manifolds The text requires some knowledge of calculus but none on differential equations or linear algebra.
In the first part of this thesis we established a maximal regularity result to the Stokes equations in exterior domains with moving boundary. This leads to existence of solutions to the Navier–Stokes equations globally in time for small data. Secondly, we consider Leray's problem on the decay of weak solutions to the Navier–Stokes equations in an exterior domain with non-homogeneous Dirichlet boundary data. It is shown that the solution decays polynomially.
Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of established agents has continued to expand, and has permitted rational drug design to play a significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.
This accessible text presents a detailed introduction to the use of a wide range of software tools and modeling environments for use in the biosciences, as well as the fundamental mathematical background. The practical constraints presented by each modeling technique are described in detail, enabling the researcher to determine which software package would be most useful for a particular problem. Features: introduces a basic array of techniques to formulate models of biological systems, and to solve them; discusses agent-based models, stochastic modeling techniques, differential equations, spatial simulations, and Gillespie’s stochastic simulation algorithm; provides exercises; describes such useful tools as the Maxima algebra system, the PRISM model checker, and the modeling environments Repast Simphony and Smoldyn; contains appendices on rules of differentiation and integration, Maxima and PRISM notation, and some additional mathematical concepts; offers supplementary material at an associated website.
This text details the principal concepts and developments in wood science, chemistry and technology. It includes new chapters on the chemical synthesis of cellulose and its technology, preservation of wood resources and the conservation of waterlogged wood.
Elementary Linear Algebra, Sixth Edition provides a solid introduction to both the computational and theoretical aspects of linear algebra, covering many important real-world applications, including graph theory, circuit theory, Markov chains, elementary coding theory, least-squares polynomials and least-squares solutions for inconsistent systems, differential equations, computer graphics and quadratic forms. In addition, many computational techniques in linear algebra are presented, including iterative methods for solving linear systems, LDU Decomposition, the Power Method for finding eigenvalues, QR Decomposition, and Singular Value Decomposition and its usefulness in digital imaging. - Prepares students with a thorough coverage of the fundamentals of introductory linear algebra - Presents each chapter as a coherent, organized theme, with clear explanations for each new concept - Builds a foundation for math majors in the reading and writing of elementary mathematical proofs
Advanced Calculus for Mathematical Modeling in Engineering and Physics introduces the principles and methods of advanced calculus for mathematical modeling, through a balance of theory and application using a state space approach with elementary functional analysis. This framework facilitates a deeper understanding of the nature of mathematical models and of the behavior of their solutions. The work provides a variety of advanced calculus models for mathematical, physical science, and engineering audiences, with discussion of how calculus-based models and their discrete analogies are generated. This valuable textbook offers scientific computations driven by Octave/MATLAB script, in recognition of the rising importance of associated numerical models. - Adopts a state space/functional analysis approach to advanced calculus-based models to provide a better understanding of the development of models and the behaviors of their solutions - Uniquely includes discrete analogies to calculus-based models, as well as the derivation of many advanced calculus models of physics and engineering– instead of only seeking solutions to the models - Offers online teaching support for qualified instructors (for selected solutions) and study materials for students (MATLAB/Octave scripts)
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