This work is based on the observation that further major advances in geochemistry, particularly in understanding the rules that govern the ways in which elements come together to form minerals and rocks, will require the application of the theories of quantum mechanics. The book therefore outlines this theoretical background and discusses the models used to describe bonding in geochemical systems. It is the first book to describe and critically review the application of quantum mechanical theories to minerals and geochemical systems. The book consolidates valuable findings from chemistry and materials science as well as mineralogy and geochemistry, and the presentation has relevance to professionals in a wide range of disciplines. Experimental techniques are surveyed, but the emphasis is on applying theoretical tools to various groups of minerals: the oxides, silicates, carbonates, borates, and sulfides. Other topics dealt with in depth include structure, stereochemistry, bond strengths and stabilities of minerals, various physical properties, and the overall geochemical distribution of the elements.
A major update of the highly popular second edition, with changes in the content and organisation that reflect advances in the subject. New and expanded topics include cytoskeleton, molecular motors, bioimaging, biomembranes, cell signalling, protein structure, and enzyme regulation. As with the first two editions, the third edition of Instant Notes in Biochemistry provides the essential facts of biochemistry with detailed explanations and clear illustrations.
Bound volume of black and white reproductions of all line art and tables from the text, allowing students to concentrate on the lecture instead of copying illustrations.
This introductory text highlights the most important aspects of a wide range of techniques used in the control of the quality of pharmaceuticals. Written with the needs of the student in mind, this clear, practical guide includes self-testing sections with arithmetical examples and tests to help students brush up on their arithmetical skills in an applied context.
In Organic Chemistry, 4th Edition, Dr. David Klein builds on the phenomenal success of the first three editions, with his skills-based approach to learning organic chemistry. The Klein program covers all the concepts typically covered in an organic chemistry course while placing a special emphasis on the skills development needed to support these concepts. Students in organic chemistry need to be able to bridge the gap between theory (concepts) and practice (problem-solving skills). Klein's SkillBuilder examples and activities offer extensive opportunities for students to develop proficiency in the key skills necessary to succeed in organic chemistry.
This book differs from other organic chemistry textbooks in that it is not focused purely on the needs of students studying premed, but rather for all students studying organic chemistry. It directs the reader to question present assumptions rather than to accept what is told, so the second chapter is largely devoted to spectroscopy (rather than finding it much later on as with most current organic chemistry textbooks). Additionally, after an introduction to spectroscopy, thermodynamics and kinetics, the presentation of structural information of compounds and organic families advances from hydrocarbons to alcohols to aldehydes and ketones and, finally, to carboxylic acids.
A Practical Guide to Geometric Regulation for Distributed Parameter Systems provides an introduction to geometric control design methodologies for asymptotic tracking and disturbance rejection of infinite-dimensional systems. The book also introduces several new control algorithms inspired by geometric invariance and asymptotic attraction for a wide range of dynamical control systems. The first part of the book is devoted to regulation of linear systems, beginning with the mathematical setup, general theory, and solution strategy for regulation problems with bounded input and output operators. The book then considers the more interesting case of unbounded control and sensing. Mathematically, this case is more complicated and general theorems in this area have become available only recently. The authors also provide a collection of interesting linear regulation examples from physics and engineering. The second part focuses on regulation for nonlinear systems. It begins with a discussion of theoretical results, characterizing solvability of nonlinear regulator problems with bounded input and output operators. The book progresses to problems for which the geometric theory based on center manifolds does not directly apply. The authors show how the idea of attractive invariance can be used to solve a series of increasingly complex regulation problems. The book concludes with the solutions of challenging nonlinear regulation examples from physics and engineering.
In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes: All-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis A completely updated categorized list of over 750 references Major advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques The latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics New coverage of mathematical modeling Expanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization
Success in organic chemistry requires mastery in two core aspects: fundamental concepts and the skills needed to apply those concepts and solve problems. With Organic Chemistry, Student Solution Manual and Study Guide, 4th Edition, students can learn to become proficient at approaching new situations methodically, based on a repertoire of skills. These skills are vital for successful problem solving in organic chemistry.
This text details the principal concepts and developments in wood science, chemistry and technology. It includes new chapters on the chemical synthesis of cellulose and its technology, preservation of wood resources and the conservation of waterlogged wood.
Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on electrochemical biosensors. New chapter on the quality control of biotechnologically produced drugs. Extended chapter on molecular emission spectroscopy. Now comes with an e-book on StudentConsult. Self-assessment is interactive in the accompanying online e-book. 65 online animations show concepts such as ionization partitioning of drug molecules etc. ~
Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals.The mathematics involved is notoriously difficult, but this much-praised and well established textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Worked calculation examples and self-assessment test questions aid continuous learning reinforcement throughout Frequent use of figures and diagrams clarify points made in the text Practical examples are used to show the application of techniques Key points boxes summarise the need to know information for each topic Focuses on the most relevant and frequently used techniques within the field
Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.
Living Chemistry is a 23-chapter textbook that provides a thorough, systematic coverage of the chemical information related to health. The opening chapters cover the basic concepts required for understanding the ""language"" and principles of chemistry. These chapters also introduce the International System of units followed by the studies of carbon compounds based on functional groups. The discussions then shift to the study of biologically important molecules, such as the chemistry of carbohydrates, lipids, and proteins, as well as the individual reaction steps for important complex metabolic pathways. The remaining chapters explore the chemistry of vitamins, hormones, body fluids, drugs and poisons. Optional topics, including a mathematics review, scientific notation, the unit-factor and proportion methods, metric conversion with practice problems, atomic orbitals, hybridization, metabolic pathways, and the cell, are provided in the supplementary texts. This book is of great value to undergraduate chemistry students.
Instant Notes in Biochemistry, 2/e provides an easy access to the fundamentals in this field. The book is a major update on the very successful first edition with expanded coverage of transcription, RNA processing and protein synthesis and many additional new topics. New illustrations have been added and much of the artwork has been enlarged or redrawn to aid comprehension.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
The field of biochemistry is entering an exciting era in which genomic information is being integrated into molecular-level descriptions of the physical processes that make life possible. The Molecules of Life is a new textbook that provides an integrated physical and biochemical foundation for undergraduate students majoring in biology or health s
The chemical study of insects has been growing for four decades, and with it an interest in how insects make their pheromones, hormones, defensive secretions, venoms, pigments and surface coverings. By investigating the biosynthesis of insects, one can gain a greater insight into the structure and function of insect compounds, into ways of disrupting biosynthetic reactions in pest species and how these pathways evolved. The first textbook of its kind, Biosynthesis in Insects amalgamates previously fragmented information and recent exciting developments in the field to provide a unique, concise chemical study of how insect substances are biosynthesised. This book provides a comprehensive introduction to the ways that have been investigated, by which a great variety of insects, and some related arthropods, make their so-called secondary metabolites. Simpler biosynthetic pathways are explored before considering the experimental methods by which these studies are conducted. Consideration is also given to some of the plant substances which insects store or metabolize to their own use. Abundantly illustrated with structures and reactions, and some beautiful photographs, Biosynthesis in Insects includes a series of problems and answers to facilitate and assess learning, making this unique look at biosynthesis in insects and their near relations ideal for students with some chemical background starting out on a study of insect substances. Researchers and academics will also welcome the amalgamation of previously scattered information. Including an index of compounds and species, and lists for further reading, this book provides a truly unique source for those working in the field.
The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm, however, we were unaware that we were toying with an idea that might enmesh us, that we were creating an entity with a life of its own, that we were letting loose a Golom who instead of being our servant would be our master. That we set up ideals for these books is obvious; they would be current guides to developments and information in the areas of mechanism of action and bio synthesis of antibiotics. For almost every subject, we wished to enlist the aid of an investigator who himself had played a part in determining the nature of the phenomena that were being discussed. One concept for the books was that they include only antibiotics for which a definitive, well-documented mechanism of action or biosynthetic pathway was known.
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross
Brain Gains: So, You Want to Be Your Child’s Learning Coach represents the final link to the first two books of the Brain Smart Trilogy. This third book recognizes the learning challenges children face each day in learning environments defined by mandated curriculums, mandated testing and shortened school years. For example, from kindergarten through high school your child will be responsible for assimilating and accommodating different school curriculums regardless that these mandated curriculums often do not take into account the many cognitive and emotional levels of each student. That is, problems can develop for those children who are not academically at the curriculum’s grade level due to multiple challenges and distractions, such as adapting to the peer group, family dynamics or disharmony (divorce, child abuse etc.), delayed physiological social development and cognitive delays that could cause a life time of learning difficulties. Finally, a major strength of this book is that it offers parents and teachers the opportunity to incorporate learning techniques used by myself and other successful learning coaches and learning specialists that readers can employ for specific student learning challenges. Most importantly, parents and teachers will not only have hands-on learning techniques but their students and/or child will receive knowledge catered to their learning needs they can employ for future learning challenges.
This is the Student Study Guide and Solutions Manual to accompany Organic Chemistry, 3e. Organic Chemistry, 3rd Edition is not merely a compilation of principles, but rather, it is a disciplined method of thought and analysis. Success in organic chemistry requires mastery in two core aspects: fundamental concepts and the skills needed to apply those concepts and solve problems. Readers must learn to become proficient at approaching new situations methodically, based on a repertoire of skills. These skills are vital for successful problem solving in organic chemistry. Existing textbooks provide extensive coverage of, the principles, but there is far less emphasis on the skills needed to actually solve problems.
Praised by faculty and students for more than two decades, Lippincott® Illustrated Reviews: Biochemistry is the long-established go-to resource for mastering the essentials of biochemistry. This best-selling text helps students quickly review, assimilate, and integrate large amounts of critical and complex information, with unparalleled illustrations that bring concepts to life. Like other titles in the popular Lippincott® Illustrated Review Series, this text follows an intuitive outline organization and boasts a wealth of study aids that clarify challenging information and strengthen retention and understanding. This updated and revised edition emphasizes clinical application and features new exercises, questions, and accompanying digital resources to ready students for success on exams and beyond.
First published over 40 years ago, this was the first text on the identification of organic compounds using spectroscopy. This text is now considered to be a classic. This text presents a unified approach to the structure determination of organic compounds based largely on mass spectrometry, infrared (IR) spectroscopy, and multinuclear and multidimensional nuclear magnetic resonance (NMR) spectroscopy. The key strength of this text is the extensive set of practice and real-data problems (in Chapters 7 and 8). Even professional chemists use these spectra as reference data. Spectrometric Identification of Organic Compounds is written by and for organic chemists, and emphasizes the synergistic effect resulting from the interplay of the spectra. This book is characterized by its problem-solving approach with extensive reference charts and tables. The 8th edition of this text maintains its student-friendly writing style - wording throughout has been updated for consistency and to be more reflective of modern usage and methods. Chapter 3 on proton NMR spectroscopy has been overhauled and updated. Also, new information on polymers and phosphorus functional groups has been added to Chapter 2 on IR spectroscopy.
As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.
This helpful tool consists of all the artwork from the textbook (more than 1,000 images), with ample space for note-taking. Because the notebook has already done the drawing, students can focus their attention on the concepts during lecture.
Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
Organic Chemistry provides a comprehensive discussion of the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. This book is written based on the premise that there are no shortcuts in organic chemistry, and that understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It lays emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall. This text covers topics ranging from structure and bonding in organic compounds to functional groups and their properties; identification of functional groups by infrared spectroscopy; organic reaction mechanisms; structures and reactions of alkanes and cycloalkanes; nucleophilic substitution and elimination reactions; conjugated alkenes and allylic systems; electrophilic aromatic substitution; carboxylic acids; and synthetic polymers. Throughout the book, principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications. There are extensive examples of biological relevance, along with a chapter on organometallic chemistry not found in other standard references. This book will be of interest to chemists, life scientists, food scientists, pharmacists, and students in the physical and life sciences. - Contains extensive examples of biological relevance - Includes an important chapter on organometallic chemistry not found in other standard references - Extended, illustrated glossary - Appendices on thermodynamics, kinetics, and transition state theory
Co-published by Sinauer Associates, Inc., and W. H. Freeman and Company. Visit the Life, Eighth Edition preview site. LIFE HAS EVOLVED. . . from its original publication to this dramatically revitalized Eighth Edition. LIFE has always shown students how biology works, offering an engaging and coherent presentation of the fundamentals of biology by describing the landmark experiments that revealed them. This edition builds on those strengths and introduces several innovations. As with previous editions, the Eighth Edition will also be available in three paperback volumes: • Volume I: The Cell and Heredity, Chapters 1-20 • Volume II: Evolution, Diversity and Ecology, Chapters 1, 21-33, 52-57 • Volume III: Plants and Animals, Chapters 1, 34-51
Plant cell culture is an essential methodology in plant sciences, with numerous variant techniques depending on the cell type and organism. Plant Cell Culture provides the reader with a concise overview of these techniques, including basic plant biology for cell culture, basic sterile technique and media preparation, specific techniques for various plant cell and tissue types including applications, tissue culture in agriculture, horticulture and forestry and culture for genetic engineering and biotechnology. This book will be an essential addition to any plant science laboratory's bookshelf.
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