David Bartolini's Books

Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

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Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

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Page Count

719

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118210778

ISBN 13

9781118210772

Hypereides

The Forensic Speeches

By: Hyperides,David Whitehead

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Hypereides

The Forensic Speeches

By: Hyperides,David Whitehead

Professor Whitehead has provided a new translation of the five surviving forensic speeches of the Athenian lawyer-politician Hypereides (390/89-322 BC). Hypereides' importance lies not only in his speeches, but also in his centrality in the political life of ancient Athens, as a contemporary of Demosthenes, and one of the canonical Ten Attic Orators. This book, which includes a general introduction and lavish historical and literary commentary, represents the first complete collection of Hypereides' works in any language.

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558

Publisher

Oxford University Press, USA

Published Date

ISBN 10

0198152183

ISBN 13

9780198152187

Left-brain Lutherie

Using Physics and Engineering Concepts for Building Guitar Family Instruments : an Introductory Guide to Their Practical Application

By: David C. Hurd

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Left-brain Lutherie

Using Physics and Engineering Concepts for Building Guitar Family Instruments : an Introductory Guide to Their Practical Application

By: David C. Hurd

This book gives the builder of guitar family instruments much greater understanding and control over the instrument building process. Predictive models and spreadsheets for many of the building steps allow the user to make intelligent choices for instrument materials and dimensions without sacrificing esthetics.

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218

Published Date

ISBN 10

0976088304

ISBN 13

9780976088301

A Call to Mission - A History of the Jesuits in China 1842-1954

Volume 2: The Wider European and American Adventure

By: David Strong

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A Call to Mission - A History of the Jesuits in China 1842-1954

Volume 2: The Wider European and American Adventure

By: David Strong

China has bulked large in the imagination of the Catholic Church for 500 years. It had been central to the missionary dream of the Jesuits for almost as long. However, only with this book's appearance has the detailed focus of attention shifted to the substantial and neglected period of catholic and Jesuit engagement with china - the almost 120 years from the second arrival of the Jesuits. Matteo Ricci the polymath, Ferdinand Verbeist and Adam Schall von Bell the astronomers and the exquisite painter who influenced Chinese painting beyond measure, Giuseppe Castiglione, have been written about, made ls of and been the heart and soul of the first stage of Jesuit impact on China - in the 17th and 18th Centuries. They brought Western learning and art to China and took Chinese language and literature to Europe. The Jesuits were the first multinational to be welcomed in China and they came with a specific method of engagement - to make friends build relationships and share their gifts before anything else was transacted, including conversations about Christianity. It remains an unsurpassed method of engagement with a rich and ancient people. But the second arrival - from the 1840's - was very different. It was made possible by the arrival of European governments and traders, many of whom came not just for financial gain but to spread their "superior" religion. This work by David Strong in two volumes is the first major treatment of the period from the arrival of the European and eventually American Jesuit missionaries under the protection of the so called Unequal Treaties through to their expulsion after the Communist victory in the long running civil war in 1949. Volume II- The Wider European Adventure- covers the commitments, places and activities of missions undertaken by the Spaniards, Austrian, Hungarians, Italians, French Canadians, and lastly in the 1930s, the Americans from California.

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Page Count

483

Publisher

ATF Press

Published Date

ISBN 10

1925643646

ISBN 13

9781925643640

Playing with Fire

European Terracotta Models, 1740-1840

By: James David Draper,Guilhem Scherf,Metropolitan Museum of Art (New York, N.Y.)

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Playing with Fire

European Terracotta Models, 1740-1840

By: James David Draper,Guilhem Scherf,Metropolitan Museum of Art (New York, N.Y.)

European sculptors of the Neoclassical period often modelled their works in clay before producing finished pieces in marble. This book offers a comprehensive overview of Neoclassical terracotta models by European artists, featuring the works of0. Pajou, Houdon, and Canova, among many others.

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342

Publisher

Metropolitan Museum of Art

Published Date

ISBN 10

1588390993

ISBN 13

9781588390998

Cesare Zavattinis Neo-realism and the Afterlife of an Idea

An Intellectual Biography

By: David Brancaleone

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Cesare Zavattinis Neo-realism and the Afterlife of an Idea

An Intellectual Biography

By: David Brancaleone

How many Zavattinis are there? During a life spanning most of the twentieth century, the screenwriter who wrote Sciuscià, Bicycle Thieves, Miracle in Milan, and Umberto D. was also a pioneering magazine publisher in 1930s Milan, a public intellectual, a theorist, a tireless campaigner for change within the film industry, a man of letters, a painter and a poet. This intellectual biography is built on the premise that in order to understand Zavattini's idea of cinema and his legacy of ethical and political cinema (including guerrilla cinema), we must also tease out the multi-faceted strands of his interventions and their interplay over time. The book is for general readers, students and film historians, and anyone with an interest in cinema and its fate.

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464

Publisher

Bloomsbury Publishing USA

Published Date

ISBN 10

1501316982

ISBN 13

9781501316982

Pharmacology for Pharmacy and the Health Sciences

A Patient-centred Approach

By: Michael Boarder,Michael R. Boarder,C. Jane Dixon,David Newby,Phyllis Navti,Tyra Zetterström

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Pharmacology for Pharmacy and the Health Sciences

A Patient-centred Approach

By: Michael Boarder,Michael R. Boarder,C. Jane Dixon,David Newby,Phyllis Navti,Tyra Zetterström

This book adopts a novel patient-centred approach to introduce drug action at the cellular and molecular level while developing clinical topics in the context of individual patients and their experience of illness. In so doing, it takes the important step of relating the scientific basis of pharmacology to real-life pharmacy practice.

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725

Publisher

Oxford University Press

Published Date

ISBN 10

0198728832

ISBN 13

9780198728832

Public Drinking in the Early Modern World Vol 3

Voices from the Tavern, 1500-1800

By: Thomas E Brennan,B Ann Tlusty,Beat Kumin,David Hancock,Michelle McDonald

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Public Drinking in the Early Modern World Vol 3

Voices from the Tavern, 1500-1800

By: Thomas E Brennan,B Ann Tlusty,Beat Kumin,David Hancock,Michelle McDonald

This four-volume reset edition presents a wide-ranging collection of primary sources which uncover the language and behaviour of local and state authorities, of peasants and town-dwellers, and of drinking companions and irate wives.

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403

Publisher

Taylor & Francis

Published Date

ISBN 10

104025117X

ISBN 13

9781040251171

What's the Economy For, Anyway?

Why It's Time to Stop Chasing Growth and Start Pursuing Happiness

By: John de Graaf,David K. Batker

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What's the Economy For, Anyway?

Why It's Time to Stop Chasing Growth and Start Pursuing Happiness

By: John de Graaf,David K. Batker

An irreverent and provocative analysis of the economy, based on the popular film by the same name, considers 13 core issues rooted in such American ideals as teamwork, pragmatism and equality to argue that we must work in tandem with markets and an active government to make the economy work for people. 30,000 first printing. Movie tie-in.

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304

Publisher

Bloomsbury Publishing USA

Published Date

ISBN 10

1608195104

ISBN 13

9781608195107

The Red Flag

A History of Communism

By: David Priestland

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The Red Flag

A History of Communism

By: David Priestland

“The best and the most accessible one-volume history of communism now available . . . A far-reaching, vividly written account.” —Foreign Affairs In The Red Flag, Oxford professor David Priestland tells the epic story of a movement that has taken root in dozens of countries across two hundred years, from its birth after the French Revolution to its ideological maturity in nineteenth-century Germany to its rise to dominance (and subsequent fall) in the twentieth century. Beginning with the first modern Communists in the age of Robespierre, Priestland examines the motives of thinkers and leaders including Marx, Engels, Lenin, Stalin, Castro, Che Guevara, Mao, Ho Chi Minh, Gorbachev, and many others. Priestland also shows how Communism, in all its varieties, appealed to different societies for different reasons, in some as a response to inequalities and in others more out of a desire to catch up with the West. But paradoxically, while destroying one web of inequality, Communist leaders were simultaneously weaving another. It was this dynamic, together with widespread economic failure and an escalating loss of faith in the system, that ultimately destroyed Soviet Communism itself. At a time when global capitalism is in crisis and powerful new political forces have arisen to confront Western democracy, The Red Flag is essential reading if we are to apply the lessons of the past to navigating the future. “Detailed and scholarly but written in lively prose, this is a rich, satisfying account of the most successful utopian political movement in history.” —Publishers Weekly, starred review

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567

Publisher

Open Road + Grove/Atlantic

Published Date

ISBN 10

0802189792

ISBN 13

9780802189790

Chestnut's Obstetric Anesthesia: Principles and Practice

By: David H. Chestnut,Linda S Polley,Cynthia A Wong,Lawrence C Tsen

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Chestnut's Obstetric Anesthesia: Principles and Practice

By: David H. Chestnut,Linda S Polley,Cynthia A Wong,Lawrence C Tsen

The updated fourth edition of this comprehensive, highly respected reference covers all you need to know about obstetric anesthesia-from basic science to various anesthesia techniques to complications. The editorial team of leading authorities in the field now features Drs. Linda S. Polley, Lawrence C. Tsen, and Cynthia A. Wong and presents the latest on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy. This edition features two new chapters and rewritten versions of key chapters such as Epidural and Spinal Analgesia and Anesthesia. Emphasizes the treatment of the fetus and the mother as separate patients with distinct needs to ensure the application of modern principles of care. Delivers contributions from many leaders in the fields of obstetric anesthesia and maternal-fetal medicine from all over the world. Offers abundant figures, tables, and boxes that illustrate the step-by-step management of a full range of clinical scenarios. Presents key point summaries in each chapter for quick, convenient reference. Features new chapters on Patient Safety and Maternal Mortality to address the latest developments in the field and keep you current. Presents completely rewritten chapters on Epidural and Spinal Analgesia and Anesthesia, Anesthesia for Cesarean Section, and Hypertension Disorders, updated by new members of the editorial team-Drs. Linda S. Polley, Lawrence C. Tsen, and Cynthia A. Wong, for state-of-the-art coverage of key topics and new insights. Covers all the latest guidelines and protocols for safe and effective practice so you can offer your patients the very best.

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4357

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323076548

ISBN 13

9780323076548

Advances in E-Engineering and Digital Enterprise Technology

Proceedings of the 4th International Conference on E-Engineering and Digital Enterprise

By: Kai Cheng,David Webb,Rodney Marsh

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Advances in E-Engineering and Digital Enterprise Technology

Proceedings of the 4th International Conference on E-Engineering and Digital Enterprise

By: Kai Cheng,David Webb,Rodney Marsh

e-Engineering and digital enterprise technology are becoming the catalysts and prime enablers for the most radical changes in industry since the industrial revolution. Advances in e-Engineering and Digital Enterprise Technology includes international papers from experts and practitioners in industry and academia providing an information exchange on all aspects of engineering and management. Providing significant contributions from practitioners , researchers, educators, and end-users, the reader will find information on the latest innovations and techniques, including, e-Engineering systems e-supply chains and e-logistics Web based CAD/CAM/CAPP Virtual and collaborative engineering Web based modelling and simulations Mass customization and customer driven engineering Tele-operation and tele-robotics. On-line education and industrial training Vital reading for leading-edge system developers, researchers, innovators, and early adopters within industry, government, and academia who are in search of excellence.

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638

Publisher

John Wiley & Sons

Published Date

ISBN 10

1860584675

ISBN 13

9781860584671

Pharmacology of Pain

By: Pierre Beaulieu,David Lussier,Frank Porreca,Anthony Dickenson

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Pharmacology of Pain

By: Pierre Beaulieu,David Lussier,Frank Porreca,Anthony Dickenson

Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain. Who should buy this book? Pharmacology of Pain is a particularly useful resource for: Basic researchers and clinicians, including physicians, dentists, pharmacists, nurses, and physical therapists Other professionals in the field of pain research and treatment Students and trainees

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978

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496331915

ISBN 13

9781496331915

Proof in Mathematics Education

Research, Learning and Teaching

By: David A. Reid,Christine Knipping

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Proof in Mathematics Education

Research, Learning and Teaching

By: David A. Reid,Christine Knipping

Research on teaching and learning proof and proving has expanded in recent decades. This reflects the growth of mathematics education research in general, but also an increased emphasis on proof in mathematics education.

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265

Publisher

BRILL

Published Date

ISBN 10

946091246X

ISBN 13

9789460912467

The Rest Principle

A Neurophysiological Theory of Behavior

By: John David Sinclair

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The Rest Principle

A Neurophysiological Theory of Behavior

By: John David Sinclair

First published in 1982. The human brain is the most complex object on Earth that can be studied scientifically: a collection of over 100 billion neurons squeezed into a space about the size of a grapefruit, which somehow is able to control all that you feel, do, and know. There still is little understanding of the most important and interesting functions of the brain, such as what really happens up there when you learn something, when you are thinking, or when you are feeling happy. In this book the author attempts to organize nearly the entire field of psychology within a single new theory, based upon only one very simple assumption about neuronal functioning.

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241

Publisher

Psychology Press

Published Date

ISBN 10

1317757858

ISBN 13

9781317757856

Pensions in Europe, European Pensions

The Evolution of Pension Policy at National and Supranational Level

By: David Natali

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Pensions in Europe, European Pensions

The Evolution of Pension Policy at National and Supranational Level

By: David Natali

This title gives scholars, students and policy-makers a comprehensive description of national retirement programmes as well as theoretical analysis of the reform politics, output and outcomes with a focus on national and European dynamics.

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294

Publisher

Peter Lang

Published Date

ISBN 10

9052014604

ISBN 13

9789052014609

Copper and Bronze in Art

Corrosion, Colorants, Conservation

By: David A. Scott

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Copper and Bronze in Art

Corrosion, Colorants, Conservation

By: David A. Scott

This is a review of 190 years of literature on copper and its alloys. It integrates information on pigments, corrosion and minerals, and discusses environmental conditions, conservation methods, ancient and historical technologies.

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536

Publisher

Getty Publications

Published Date

ISBN 10

0892366389

ISBN 13

9780892366385

The Ruin of the Eternal City

Antiquity and Preservation in Renaissance Rome

By: David Karmon

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The Ruin of the Eternal City

Antiquity and Preservation in Renaissance Rome

By: David Karmon

The Ruin of the Eternal City provides the first systematic analysis of the preservation practices of the popes, civic magistrates, and ordinary citizens of Renaissance Rome. This study offers a new understanding of historic preservation as it occurred during the extraordinary rebuilding of a great European capital city.

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336

Publisher

Oxford University Press

Published Date

ISBN 10

0199877467

ISBN 13

9780199877461

Disenfranchising Democracy

Constructing the Electorate in the United States, the United Kingdom, and France

By: David A. Bateman

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Disenfranchising Democracy

Constructing the Electorate in the United States, the United Kingdom, and France

By: David A. Bateman

The first wave of democratization in the United States - the removal of property and taxpaying qualifications for the right to vote - was accompanied by the disenfranchisement of African American men, with the political actors most supportive of the former also the most insistent upon the latter. The United States is not unique in this respect: other canonical cases of democratization also saw simultaneous expansions and restrictions of political rights, yet this pattern has never been fully detailed or explained. Through case studies of the USA, the UK, and France, Disenfranchising Democracy offers the first cross-national account of the relationship between democratization and disenfranchisement. It develops a political institutional perspective to explain their co-occurrence, focusing on the politics of coalition-building and the visions of political community coalitions advance in support of their goals. Bateman sheds new light on democratization, connecting it to the construction of citizenship and cultural identities.

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369

Publisher

Cambridge University Press

Published Date

ISBN 10

1108601286

ISBN 13

9781108601283

The Political Influence of Business in the European Union

By: Andreas Dur,David Marshall,Patrick Bernhagen

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The Political Influence of Business in the European Union

By: Andreas Dur,David Marshall,Patrick Bernhagen

Many citizens, politicians, and political activists voice concern about the political influence of business in the European Union. But do business interests really pull the strings in Brussels? Contrary to expectations, this book shows that business interests are no more influential than other interests in shaping contemporary EU policies. Andreas Dür, David Marshall, and Patrick Bernhagen present an original argument that stresses the role of public actors in facilitating or impeding interest groups’ lobbying success. Novel data on a large number of legislative proposals on the EU’s agenda and three case studies present strong support for this argument. The Political Influence of Business in the European Union offers new insights into how lobbying success depends on the demand and supply of information, as well as new ideas on how to measure lobbying success. The book advances a fresh perspective on the question of business power and shows why business interests often lose in the policy struggle.

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221

Publisher

University of Michigan Press

Published Date

ISBN 10

0472124641

ISBN 13

9780472124640

Paleobiology of the Polycystine Radiolaria

By: David Lazarus,Noritoshi Suzuki,Yoshiyuki Ishitani,Kozo Takahashi

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Paleobiology of the Polycystine Radiolaria

By: David Lazarus,Noritoshi Suzuki,Yoshiyuki Ishitani,Kozo Takahashi

Polycystine radiolaria are exclusively marine protists and are found in all ocean waters, from polar regions to the tropics, and at all water depths. There are approximately 600 distinct described living species and several thousand fossil species of polycystines. Radiolarians in general, and polycystines in particular, have recently been shown to be a major component of the living plankton and important to the oceanic carbon cycle. As fossils radiolarians are also fairly common, and often occur in sediments where other types of fossils are absent. This has made them very valuable for certain types of geologic research, particularly estimating the geologic age of the sediments containing them, and as guides to past oceanic water conditions. As our current understanding of the biology, and even taxonomy of the living fauna is still very incomplete, evolutionary studies based on living polycystines are still rare. However, the common occurrence of numerous specimens for many species, and in a wide variety of oceanic environments, provides an excellent opportunity to study the processes of biologic evolution in the fossil record. Paleobiology of the Polycystine Radiolaria is the first major book on radiolarians to appear in the western literature since 2001. Focusing on living and fossil siliceous shelled radiolarians, it is notable for its emphasis not upon morphologic or taxonomic detail but on concepts and applications. The book attempts to provide a balanced, critical review of what is known of the biology, ecology, and fossil record of the group, as well as their use in evolutionary, biostratigraphic and paleoceanographic research. Full chapters on the history of study, and molecular biology, are the first ever in book form. Written for an audience of advanced undergraduate to doctoral students, as well as for a broad range of professionals in the biological and Earth sciences, Paleobiology of the Polycystine Radiolaria summarizes current understanding of the marine planktonic protist group polycystine radiolaria, both in living and fossil form.

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528

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470671440

ISBN 13

9780470671443

A Bed for the Night

Humanitarianism in Crisis

By: David Rieff

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A Bed for the Night

Humanitarianism in Crisis

By: David Rieff

Timely and controversial, A Bed for the Night reveals how humanitarian organizations trying to bring relief in an ever more violent and dangerous world are often betrayed and misused, and have increasingly lost sight of their purpose. Humanitarian relief workers, writes David Rieff, are the last of the just. And in the Bosnias, the Rwandas, and the Afghanistans of this world, humanitarianism remains the vocation of helping people when they most desperately need help, when they have lost or stand at risk of losing everything they have, including their lives. Although humanitarianism's accomplishments have been tremendous, including saving countless lives, the lesson of the past ten years of civil wars and ethnic cleansing is that it can do only so much to alleviate suffering. Aid workers have discovered that while trying to do good, their efforts may also cause harm. Drawing on firsthand reporting from hot war zones around the world -- Bosnia, Rwanda, Congo, Kosovo, Sudan, and most recently Afghanistan -- Rieff describes how the International Committee of the Red Cross, Doctors Without Borders, the International Rescue Committee, CARE, Oxfam, and other humanitarian organizations have moved from their founding principle of political neutrality, which gave them access to victims of wars, to encouraging the international community to take action to stop civil wars and ethnic cleansing. This advocacy has come at a high price. By calling for intervention -- whether by the United Nations or by "coalitions of the willing" -- humanitarian organizations risk being seen as taking sides in a conflict and thus jeopardizing their access to victims. And by overreaching, the humanitarian movement has allowed itself to be hijacked by the major powers, at times becoming a fig leaf for actions those powers wish to take for their own interests, or for the major powers' inaction. Rieff concludes that if humanitarian organizations are to do what they do best -- alleviate suffering -- they must reclaim their independence. Except for relief workers themselves, no one has looked at humanitarian action as seriously or as unflinchingly, or has had such unparalleled access to its inner workings, as Rieff, who has traveled and lived with aid workers over many years and four continents. A cogent, hard-hitting report from the front lines, A Bed for the Night shows what international aid organizations must do if they are to continue to care for the victims of humanitarian disasters.

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402

Publisher

Simon and Schuster

Published Date

ISBN 10

074325211X

ISBN 13

9780743252119

Plants and the Human Brain

By: David O. Kennedy

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Plants and the Human Brain

By: David O. Kennedy

Discusses how plant-based chemicals affect and interact with the human brain and its evolution.

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395

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Oxford University Press

Published Date

ISBN 10

019991401X

ISBN 13

9780199914012

Italy and the Potato: A History, 1550-2000

By: David Gentilcore

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Italy and the Potato: A History, 1550-2000

By: David Gentilcore

Italy, like the rest of Europe, owes a lot to the 'Columbian exchange'. As a result of this process, in addition to potatoes, Europe acquired maize, tomatoes and most types of beans. All are basic elements of European diet and cookery today. The international importance of the potato today as the world's most cultivated vegetable highlights its place in the Columbian exchange. While the history of the potato in the United States, Ireland, Britain and other parts of northern Europe is quite well known, little is known about the slow rise and eventual fall of the potato in Italy. This book aims to fill that gap, arguing why the potato's 'Italian' history is important. It is both a social and cultural history of the potato in Italy and a history of agriculture in marginal areas. David Gentilcore examines the developing presence of the potato in elite and peasant culture, its place in the difficult mountain environment, in family recipe notebooks and kitchen accounts, in travellers' descriptions, agronomical treatises, cookery books, and in Italian literature.

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Page Count

273

Publisher

Bloomsbury Publishing

Published Date

ISBN 10

1441176268

ISBN 13

9781441176264

Book's by David Bartolini

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