This scholarly work looks at the issue of politics and performance in America today with particular attention paid to performances produced by activists, the NEA Four, and "Miss Saigon".
Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Massive thrombosis or bleeding, hereditary angioedema, Alzheimer''s disease, diabetic angiopathy and tumor invasion are some of the human diseases associated with serpins. In addition, mutations that alter serpin conformations (the serpinopathies) lead to lung disease, cirrhosis and a form of familial dementia. The goal of this text is to present the current knowledge on the molecular and cellular basis of serpins and their diseases.
Rights advocacy has become a prominent facet of South Korea’s increasingly transnational motion picture output, especially following the 1998 presidential inauguration of Kim Dae-jung, a former political prisoner and victim of human rights abuses who received the Nobel Peace Prize in 2000. Today it is not unusual to see a big-budget production about the pursuit of social justice or the protection of civil liberties contending for the top spot at the box office. With that cultural shift has come a diversification of film subjects, which range from undocumented workers’ rights to the sexual harassment experienced by women to high-school bullying to the struggles among people with disabilities to gain inclusion within a society that has transformed significantly since winning democratic freedoms three decades ago. Combining in-depth textual analyses of films such as Bleak Night, Okja, Planet of Snail, Repatriation, and Silenced with broader historical contextualization, Movie Minorities offers the first English-language study of South Korean cinema’s role in helping to galvanize activist social movements across several identity-based categories.
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