David A. Hopwood's Books

Streptomyces in Nature and Medicine

The Antibiotic Makers

By: David A. Hopwood

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Streptomyces in Nature and Medicine

The Antibiotic Makers

By: David A. Hopwood

This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.

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Page Count

261

Publisher

Oxford University Press

Published Date

ISBN 10

0199722285

ISBN 13

9780199722280

Principles and Practice of Lung Cancer

The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC)

By: Harvey I. Pass,David P. Carbone,David H. Johnson,John D. Minna,Giorgio V. Scagliotti,Andrew T. Turrisi

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Principles and Practice of Lung Cancer

The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC)

By: Harvey I. Pass,David P. Carbone,David H. Johnson,John D. Minna,Giorgio V. Scagliotti,Andrew T. Turrisi

Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.

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Page Count

1056

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1451152965

ISBN 13

9781451152968

A Good American Family

The Red Scare and My Father

By: David Maraniss

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A Good American Family

The Red Scare and My Father

By: David Maraniss

Pulitzer Prize–winning author and “one of our most talented biographers and historians” (The New York Times) David Maraniss delivers a “thoughtful, poignant, and historically valuable story of the Red Scare of the 1950s” (The Wall Street Journal) through the chilling yet affirming story of his family’s ordeal, from blacklisting to vindication. Elliott Maraniss, David’s father, a WWII veteran who had commanded an all-black company in the Pacific, was spied on by the FBI, named as a communist by an informant, called before the House Un-American Activities Committee in 1952, fired from his newspaper job, and blacklisted for five years. Yet he never lost faith in America and emerged on the other side with his family and optimism intact. In a sweeping drama that moves from the Depression and Spanish Civil War to the HUAC hearings and end of the McCarthy era, Maraniss weaves his father’s story through the lives of his inquisitors and defenders as they struggle with the vital 20th-century issues of race, fascism, communism, and first amendment freedoms. “Remarkably balanced, forthright, and unwavering in its search for the truth” (The New York Times), A Good American Family evokes the political dysfunctions of the 1950s while underscoring what it really means to be an American. It is “clear-eyed and empathetic” (Publishers Weekly, starred review) tribute from a brilliant writer to his father and the family he protected in dangerous times.

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Page Count

432

Publisher

Simon & Schuster

Published Date

ISBN 10

1501178393

ISBN 13

9781501178399

A Social Critique of Corporate Reporting

Semiotics and Web-based Integrated Reporting

By: David Crowther

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A Social Critique of Corporate Reporting

Semiotics and Web-based Integrated Reporting

By: David Crowther

In the critically acclaimed first edition of A Social Critique of Corporate Reporting, David Crowther examined the perceived dialectic around traditional and environmental reporting to show it to be a false dialectic. Corporate reporting continues to change rapidly to incorporate more detail and especially environmental and social information. At the same time the mechanism for reporting has changed and the internet now enables more information to be provided to an ever wider range of stakeholders and interest groups. The perceived conflict between financial performance representing the needs of investors and other dimensions of performance representing the needs of other stakeholders still however continues to exist. In this updated edition, this perceived conflict is re-examined along with the wider purposes of corporate reporting. These are examined in the context of web based reporting and a greater concern for all stakeholders. The conclusion is that, although recent developments have produced changes, the essential conflict is still professed to exist, but remains a largely imaginary one. The analysis in this book makes use of both statistics and semiotics and in so doing develops a semiology of corporate reporting that offers an alternative to other research that is largely based on econometrics. Researchers, higher level students and others with an interest in or responsibility for corporate reporting, corporate social responsibility, accounting research, or semiotics will find this book essential reading.

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Page Count

339

Publisher

Routledge

Published Date

ISBN 10

1317186788

ISBN 13

9781317186786

A Social Critique of Corporate Reporting: A Semiotic Analysis of Corporate Financial and Environmental Reporting

A Semiotic Analysis of Corporate Financial and Environmental Reporting

By: David Crowther

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A Social Critique of Corporate Reporting: A Semiotic Analysis of Corporate Financial and Environmental Reporting

A Semiotic Analysis of Corporate Financial and Environmental Reporting

By: David Crowther

This title was first published in 2002: This text is concerned with the role of corporate reporting in UK public limited companies. It is a common assumption that the most significant part of any corporate report is the accounting information contained within. This book, however, takes a different view. The central argument is that the purpose of corporate reporting has changed from one primarily of stewardship and accountability to shareholders to a more outward- and forward-looking perspective. The author argues that one of the driving forces for this change in orientation is the discourse of environmental accounting, along with other forces. The book is essentially explorative. The author is concerned with looking at different aspects of the changes in corporate reporting and taking different perspectives in the development of the argument.

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Page Count

347

Publisher

Routledge

Published Date

ISBN 10

1351735926

ISBN 13

9781351735926

Yearbook of Science and the Future

By: David Calhoun

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Yearbook of Science and the Future

By: David Calhoun

This yearbook presents and interprets current trends and discoveries in a review of the science year. The yearbook includes feature articles on science fiction, the Voyager space probe and scientific discoveries. It also features a Britannica science update section.

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Page Count

520

Published Date

ISBN 10

0852295251

ISBN 13

9780852295250

Handbook of Section 1983 Litigation, 2012 Edition

By: David W. Lee

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Handbook of Section 1983 Litigation, 2012 Edition

By: David W. Lee

If you need the short answer to a Section 1983 question, and you can't afford to waste time running down the wrong research path, turn to the Handbook of Section 1983 Litigation, 2012 Edition. This essential guide is designed as the practitioner's desk book. It provides quick and concise answers to issues that frequently arise in Section 1983 cases, from police misconduct to affirmative actions to gender and race discrimination. It is organized to help you quickly find the specific information you need whether you're counsel for the plaintiff or defendant. You will find a clear, concise statement of the law governing every aspect of a Section 1983 claim, extensive citation to legal authority, every major Supreme Court ruling on Section 1983, as well as key opinions in every circuit, and a detailed overview of case law. The Handbook of Section 1983 Litigation, 2012 Edition is written by David Lee, a practicing expert with 20 years of litigation experience. He has lectured on civil rights topics before thousands of litigators during his career, and argued four cases before the United States Supreme Court, as well as numerous cases before the Tenth Circuit Court of Appeals. This new updated 2012 Edition features coverage of recent important Section 1983 U.S. Supreme Court cases including: Skinner v. Switzer Arizona Christian School Tuition Organization v. Winn Camreta v. Greene NASA v. Nelson Connick v. Thompson Brown v. Plata Swarthout v. Cook Turner v. Rogers Duryea v. Guarnieri Arizona Free Enterprise Club's Freedom Club PAC v. Bennett Brown v. Entertainment Merchants Association Ortiz v. Jordan Fox v. Vice This is the one reference to keep at your fingertips at a hearing, trial, or deposition when dealing with Section 1983 cases.

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Page Count

1368

Publisher

Wolters Kluwer

Published Date

ISBN 10

145480985X

ISBN 13

9781454809852

Words to Measure a War

Nine American Poets of World War II

By: David K. Vaughan

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Words to Measure a War

Nine American Poets of World War II

By: David K. Vaughan

This is a study of the war poetry of nine American men who served in World War II. The efforts of those who had established themselves as poets prior to or during the war (Karl Shapiro, Randall Jarrell, John Ciardi, and William Meredith) are compared with those whose poetic careers began after the war (Louis Simpson, James Dickey, Richard Hugo, Howard Nemerov, and Lincoln Kirstein). The military careers of these soldiers illuminate how their experiences affected the content as well as style of their poems. Each man's poetry directly related to his involvement with the combat environment: the closer the combat experience, the more personal the poetry; the more distant the experience, the more detached the poetry.

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Page Count

205

Publisher

McFarland

Published Date

ISBN 10

0786443065

ISBN 13

9780786443062

Book's by David A. Hopwood

Streptomyces in Nature and Medicine

Streptomyces in Nature and Medicine

Principles and Practice of Lung Cancer

Principles and Practice of Lung Cancer

A Good American Family

A Good American Family

A Social Critique of Corporate Reporting

A Social Critique of Corporate Reporting

A Social Critique of Corporate Reporting: A Semiotic Analysis of Corporate Financial and Environmental Reporting

A Social Critique of Corporate Reporting: A Semiotic Analysis of Corporate Financial and Environmental Reporting

Yearbook of Science and the Future

Yearbook of Science and the Future

Handbook of Section 1983 Litigation, 2012 Edition

Handbook of Section 1983 Litigation, 2012 Edition

Words to Measure a War

Words to Measure a War

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