HIV infection involves all systems of our body and diseases manifest in atypical and severe forms leading to lot of morbidity and mortality. Skin being the largest organ of the body and with mucous membranes, it is the main portal of HIV infection. There is a lot of scope for research in the field of HIV and AIDS, and there is a need for an updated literature that would throw a light on the efficient diagnosis and management of cutaneous manifestations in HIV disease. Hence we are bringing out this eBook which is a comprehensive literature on HIV and its various cutaneous manifestations in its entirety. In this eBook we have provided extensive data and information on various skin related infections, papulosquamous disorders, disorders of vasculature, pruritic papular eruptions, neoplasias, adverse drug reactions and other hair, nail, oral and ocular associated disorders in HIV. The work has been sufficiently researched and contributed by experts in this field. Clinical photographs and extensive scientific literature will enhance the knowledge and confidence of the readers particularly clinicians and postgraduates to efficiently diagnose and manage cutaneous diseases in HIV infected patients. We acknowledge the work and sincere efforts of all the contributors who have made this project to happen. Sincere thanks to Dr. Eswari L and Dr. Shwetha S for their support and help in bringing out this edition. Thanks to my spouse and daughters for their encouragement and support and especially to the publishers without whom this work would go unnoticed. We hope that this conscious effort will benefit the readers and in turn the people living with HIV- AIDS at large.