Driven by the advancement of industrial mathematics and the need for impact case studies, Inverse Problems with Applications in Science and Engineering thoroughly examines the state-of-the-art of some representative classes of inverse and ill-posed problems for partial differential equations (PDEs). The natural practical applications of this examination arise in heat transfer, electrostatics, porous media, acoustics, fluid and solid mechanics – all of which are addressed in this text. Features: Covers all types of PDEs — namely, elliptic (Laplace’s, Helmholtz, modified Helmholtz, biharmonic and Stokes), parabolic (heat, convection, reaction and diffusion) and hyperbolic (wave) Excellent reference for post-graduates and researchers in mathematics, engineering and any other scientific discipline that deals with inverse problems Contains both theory and numerical algorithms for solving all types of inverse and ill-posed problems
This book presents the use of efficient Evolutionary Computation (EC) algorithms for solving diverse real-world image processing and pattern recognition problems. It provides an overview of the different aspects of evolutionary methods in order to enable the reader in reaching a global understanding of the field and, in conducting studies on specific evolutionary techniques that are related to applications in image processing and pattern recognition. It explains the basic ideas of the proposed applications in a way that can also be understood by readers outside of the field. Image processing and pattern recognition practitioners who are not evolutionary computation researchers will appreciate the discussed techniques beyond simple theoretical tools since they have been adapted to solve significant problems that commonly arise on such areas. On the other hand, members of the evolutionary computation community can learn the way in which image processing and pattern recognition problems can be translated into an optimization task. The book has been structured so that each chapter can be read independently from the others. It can serve as reference book for students and researchers with basic knowledge in image processing and EC methods.
Metallic Mineral Resources: The Critical Components for a Sustainable Earth serves the increasing interest in metal resources, especially the critical and strategic metals which are essential commodities for the green energy transition. The opening chapters introduce the heterogeneous distribution of metal resources as well as the industrial use of metals. The main chapters then work systematically through abundant metal systems, scarce critical metal systems, rare critical metal systems, trace critical metal systems, and precious metal systems. The book wraps with a close examination of temporal distribution of mineral resources and an insightful discussion of the future of mineral resources. Researchers and engineers in economic geology and mining and exploration industries will find themselves returning to this key reference for years to come.• Describes how mineable and economic metal concentrations form and are preserved in the Earth's upper crust • Explores how they are discovered by systematic mineral exploration at a variety of scales • Discusses how to educate the public on the scarcity of natural metal resources and the issues concerning the nexus between the energy transition and potential exhaustion of critical metals
Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike. - Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification. - Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria. - Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. - Details the latest insights on the molecular biology of benign and malignant hematologic disorders. - Features more than 1,100 high-quality color images that mirror the findings you encounter in practice. - Uses an easy-to-navigate, templated format with standard headings in each chapter. - Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis. - Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.
Wastewater Treatment Residues as Resources for Biorefinery Products and Energy reviews wastewater treatment processes and the use of residues. The viability of end use processes for residues, such as incineration, cement additives, agricultural fertilizers, and methane production are reviewed and analyzed, as are new processes for the use of residues within a fuels production system, such as pyrolysis, hydrothermal liquefaction and syngas. Specialized chapters discuss fractionation of biomass, the production of compounds from volatile fatty acids that conceptually proceed from the anaerobic acidogenesis of residues, and a final analysis of the overall productivity and viability that can be expected from these production schemes. - Discusses processes for the production of high value-added products and energy development from sludge - Provides value-added technologies for resource utilization in wastewater systems - Outlines sustainability assessments and comparisons of technologies and processes
Manage and Automate Data Analysis with Pandas in Python Today, analysts must manage data characterized by extraordinary variety, velocity, and volume. Using the open source Pandas library, you can use Python to rapidly automate and perform virtually any data analysis task, no matter how large or complex. Pandas can help you ensure the veracity of your data, visualize it for effective decision-making, and reliably reproduce analyses across multiple data sets. Pandas for Everyone, 2nd Edition, brings together practical knowledge and insight for solving real problems with Pandas, even if you’re new to Python data analysis. Daniel Y. Chen introduces key concepts through simple but practical examples, incrementally building on them to solve more difficult, real-world data science problems such as using regularization to prevent data overfitting, or when to use unsupervised machine learning methods to find the underlying structure in a data set. New features to the second edition include: Extended coverage of plotting and the seaborn data visualization library Expanded examples and resources Updated Python 3.9 code and packages coverage, including statsmodels and scikit-learn libraries Online bonus material on geopandas, Dask, and creating interactive graphics with Altair Chen gives you a jumpstart on using Pandas with a realistic data set and covers combining data sets, handling missing data, and structuring data sets for easier analysis and visualization. He demonstrates powerful data cleaning techniques, from basic string manipulation to applying functions simultaneously across dataframes. Once your data is ready, Chen guides you through fitting models for prediction, clustering, inference, and exploration. He provides tips on performance and scalability and introduces you to the wider Python data analysis ecosystem. Work with DataFrames and Series, and import or export data Create plots with matplotlib, seaborn, and pandas Combine data sets and handle missing data Reshape, tidy, and clean data sets so they’re easier to work with Convert data types and manipulate text strings Apply functions to scale data manipulations Aggregate, transform, and filter large data sets with groupby Leverage Pandas’ advanced date and time capabilities Fit linear models using statsmodels and scikit-learn libraries Use generalized linear modeling to fit models with different response variables Compare multiple models to select the “best” one Regularize to overcome overfitting and improve performance Use clustering in unsupervised machine learning
The triggered release of functional compounds from such polymeric carriers as micelles, nanoparticles or nanogels is a rapidly developing and highly versatile concept which is expected to be one of the key approaches to future therapeutics. In his thesis, Daniel Klinger highlights the approach of stimuli-responsive microgels for such applications and discusses why especially light as a trigger has an outstanding position amongst the family of conventional stimuli. Based on these considerations, the author focuses on the design, synthesis and characterization of novel photo-sensitive microgels and nanoparticles as potential materials for the loading and light-triggered release/accessibility of functional compounds. Starting from the synthesis of photo-cleavable organic building blocks and their use in the preparation of polymeric nanoparticles, continuing to the examination of their loading and release profiles, and concluding with biological in vitro studies of the final materials, Daniel Klinger’s work is an excellent example of the multidisciplinary research needed for the successful development of new materials in this field and has led to a number of further publications in internationally respected journals.
State Estimation Strategies in Lithium-ion Battery Management Systems presents key technologies and methodologies in modeling and monitoring charge, energy, power and health of lithium-ion batteries. Sections introduce core state parameters of the lithium-ion battery, reviewing existing research and the significance of the prediction of core state parameters of the lithium-ion battery and analyzing the advantages and disadvantages of prediction methods of core state parameters. Characteristic analysis and aging characteristics are then discussed. Subsequent chapters elaborate, in detail, on modeling and parameter identification methods and advanced estimation techniques in different application scenarios. Offering a systematic approach supported by examples, process diagrams, flowcharts, algorithms, and other visual elements, this book is of interest to researchers, advanced students and scientists in energy storage, control, automation, electrical engineering, power systems, materials science and chemical engineering, as well as to engineers, R&D professionals, and other industry personnel. - Introduces lithium-ion batteries, characteristics and core state parameters - Examines battery equivalent modeling and provides advanced methods for battery state estimation - Analyzes current technology and future opportunities
In this book, the author focuses on the physics behind dew, breaths figures, and dropwise condensation phenomena to introduce scientists, engineers and students to the many original processes involved in condensation. Consisting of 15 Chapters, 18 Appendices and over 500 references, the reader learns the needed theoretical backgrounds and formulae to understand the complexity of dropwise condensation. Heat and mass transfer, nucleation and growth on various substrates are considered (solid, liquid, plastic, undergoing phase change or micro-patterned substrates). The particular role of thermal or geometrical discontinuities where growth can be enhanced or reduced, dynamical aspects of self-diffusion, problems related to drop collection by gravity and the optics of dropwise condensation are all discussed. Although the content mainly deals with condensation from humid air, it can readily be generalized to condensation of any substance. The specificities of pure vapor condensation (e.g. steam) are also examined. Numerous images are provided within the text to illustrate the physics. This book is meant for those studying or researching dew and dropwise condensation, but also for individuals wishing to develop their knowledge on the subject.
Recent years has seen a tremendous growth in interest for solid state batteries based on polymer electrolytes, with advantages of higher safety, energy density, and ease of processing. The book explains which polymer properties guide the performance of the solid-state device, and how these properties are best determined. It is an excellent guide for students, newcomers and experts in the area of solid polymer electrolytes.
El emprendimiento es un determinante fundamental del crecimiento y la creación de empleo. Pese a que los emprendedores abundan en América Latina y el Caribe, las empresas de la región son más pequeñas y menos propensas a crecer e innovar que las de otras regiones. El crecimiento de la productividad lleva décadas siendo mediocre y el reciente period de auge de las materias primas no ha supuesto una excepción. Así pues, la presencia de emprendedores dinámicos será necesaria para impulsar la creación de puestos de trabajo de calidad y la aceleración del crecimiento de la productividad en la región. En El emprendimiento en América Latina: muchas empresas y poca innovación se estudia el panorama del emprendimiento en América Latina y el Caribe. El libro recurre a nuevas bases de datos que abordan cuestiones como la creación de empresas, las dinámicas empresariales, las decisiones de exportar y el comportamiento de las corporaciones multinacionales y sintetiza los resultados de un análisis exhaustivo del estatus, las perspectivas y los retos del emprendimiento en la región. Asimismo, el libro suministra herramientas útiles e información para ayudar a los profesionales y responsables de las políticas a identificar los ámbitos de las mismas que los gobiernos pueden explorar para impulsar la innovación e incentivar el emprendimiento transformador con potencial de crecimiento elevado.
FOREST ECOLOGY Authoritative resource covering traditional plant ecology topics and contemporary components such as climate change, invasive species, ecosystem services, and more Forest Ecology provides comprehensive coverage of the field, focusing on traditional plant ecology topics of tree structure and growth, regeneration, effects of light and temperature on tree physiology, forest communities, succession, and diversity. The work also reviews abiotic factors of light, temperature, physiography (landforms and topography), soil, and disturbance (especially fire), and provides coverage of ecosystem-level topics including carbon storage and balance, nutrient cycling, and forest ecosystem productivity. The 5th edition of Forest Ecology retains the readability and accessibility of the previous editions and includes important additional topical material that has surfaced in the field. All topics are approached with a landscape ecosystem or geo-ecological view, which places biota (organisms and communities) in context as integral parts of whole ecosystems that also include air (atmosphere and climate), topography, soil, and water. As such, the book fills a niche utilized by no other forest ecology text on the market, helping students and researchers consider whole ecosystems at multiple scales. Sample topics covered in Forest Ecology include: Contemporary components of forest ecology, including climate change, invasive species, diversity, ecological forestry, landscape ecology, and ecosystem services. Characteristics of physiography important for forest ecosystems, including its effects on microclimate, disturbance, soil, and vegetation. Genetic diversity of woody plants and genecological differentiation of tree species, including the importance of hybridization, polyploidy, and epigenetics. Site quality estimation using tree height and ground flora, and multiple-factor approaches to forest site and ecosystem classification and mapping. Forest Ecology is a highly accessible text for students, but it also serves as an excellent reference for academics. In addition, practitioners of forest ecology can also harness the information within to gain better insight into the field for practical application of concepts.
Widely used by residents, fellows, and practicing pathologists around the world, Gattusso's Differential Diagnosis in Surgical Pathology provides a user-friendly road map to the main criteria to consider in order to differentiate between a variety of potential diagnoses that all have a very similar appearance. This comprehensive guide helps you make informed decisions for even your most complex and challenging cases, presenting a comprehensive differential diagnosis list and comparisons for every entity discussed. The 4th Edition brings you fully up to date with updated diagnostic techniques, new classifications, and new content throughout—perfect for quick reference at every microscope in the sign-out room. - Provides brief descriptions of both common and uncommon disorders, with an emphasis on differential diagnosis, along with excellent illustrative examples of the pathology and carefully selected references. - Streamlines the differential diagnosis process by offering a series of bullet point checklists that detail the respective features of the entities being considered. - Discusses a complete range of tumors and tumor-like conditions in all organ systems. - Contains updated information on personalized/precision medicine especially as it pertains to the immunotherapies; for example, PDL-1 targeted therapies in many cancers. - Includes new classification of neuroendocrine tumors, new classification and updates of follicular variant of papillary thyroid carcinoma, and a new section on the most common metastatic tumors and utilization of ancillary techniques for diagnosis and molecular studies. - Uses a reader friendly, outline format for each diagnosis that details clinical information, epidemiology, gross and microscopic findings, ancillary stains and tests, differential diagnoses, and pearls of wisdom. - Features 1,400 full-color macro- and micrographs that provide a realistic basis for comparison of what you see under the microscope. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
The field of Artificial Neural Networks is the fastest growing field in Information Technology and specifically, in Artificial Intelligence and Machine Learning.This must-have compendium presents the theory and case studies of artificial neural networks. The volume, with 4 new chapters, updates the earlier edition by highlighting recent developments in Deep-Learning Neural Networks, which are the recent leading approaches to neural networks. Uniquely, the book also includes case studies of applications of neural networks — demonstrating how such case studies are designed, executed and how their results are obtained.The title is written for a one-semester graduate or senior-level undergraduate course on artificial neural networks. It is also intended to be a self-study and a reference text for scientists, engineers and for researchers in medicine, finance and data mining.
Biobased Surfactants: Synthesis, Properties, and Applications, Second Edition, covers biosurfactant synthesis and applications and demonstrates how to reduce manufacturing and purification costs, impurities, and by-products. Fully updated, this book covers surfactants in biomedical applications, detergents, personal care, food, pharmaceuticals, cosmetics, and nanotechnology. It reflects on the latest developments in biobased surfactant science and provides case scenarios to guide readers in efficient and effective biobased surfactant application, along with strategies for research into new applications. This book is written from a biorefinery-based perspective by an international team of experts and acts as a key text for researchers and practitioners involved in the synthesis, utilization, and development of biobased surfactants. - Describes new and emerging biobased surfactants and their synthesis and development - Showcases an interdisciplinary approach to the topic, featuring applications to chemistry, biotechnology, biomedicine, and other areas - Presents the entire lifecycle of biobased surfactants in detail
Offering authoritative, comprehensive coverage of hip surgery, the 2nd Edition of Surgery of the Hip is the definitive guide to hip replacement, other open and arthroscopic surgical procedures, and surgical and nonsurgical management of the hip across the lifespan. Modeled after Insall & Scott Surgery of the Knee, it keeps you fully up to date with the latest research, techniques, tools, and implants, enabling you to offer both adults and children the best possible outcomes. Detailed guidance from expert surgeons assists you with your toughest clinical challenges, including total hip arthroplasty, pediatric hip surgery, trauma, and hip tumor surgery. - Discusses new topics such as direct anterior approach for total hip arthroplasty, hip pain in the young adult, and hip preservation surgery. - Contains new coverage of minimally invasive procedures, bearing surface selection, management of complications associated with metal and metal bearing surfaces, management of bone loss associated with revision THA, and more. - Provides expert, personal advice in "Author's Preferred Technique" sections. - Helps you make optimal use of the latest imaging techniques, surgical procedures, equipment, and implants available. - Covers tumors of the hip, hip instability and displacement in infants and young children, traumatic injuries, degenerative joint disorders, and rehabilitation considerations—all from both a basic science and practical clinical perspective.
I wrote this book urged by the overwhelming desire that arises towards the end of life to recapitulate the past. My goal was to summarize my experience of practicing science at the end of the 20th and early 21st centuries in Argentina, a country located far away from the world’s leading scientific centers. In the book, I summarize the intricacies of the pineal gland (“the stone of madness”) as historical, mystical and medical entity and its entry in contemporary medicine with the description of melatonin. I also reflect on how being associated with an unexplored subject at the beginning of his scientific career impacts the life of a scientist throughout their entire life. Today we know that in humans pineal melatonin is released every day late in the evening, and there is evidence that it is the trigger for the sleep process. But the most exciting aspect of melatonin is that it is a substance that is present in all living creatures, from unicellular organisms to plants and higher mammals, a fact that evinces its importance for life. Further, the neuroprotective action of melatonin promises to be crucial for the control of neurodegenerative diseases we face as a pandemic in this century. The discoverer of melatonin, Aaron Lerner, based its name on melano, the Greek word for black, because of its effect on the pigment cells of the skin. As in "La vie en rose", the immortal Edith Piaf song written in 1946, my lifelong work with melatonin could well be called "Ma vie en noir".
Never before has a holistic approach to sustainable agriculture and plant physiology been presented in one source. This book compiles a multi-authored and international perspective on the ways in which crop physiology could be integrated with other disciplines. With a focus on genetic improvement and agronomy, this book addresses the challenges of environmentally sound production of bulk and quality food, fodder, fiber and energy, which are of ongoing international concern. - Provides a view of crop physiology as an active source of methods, theories, ideas and tools for application in genetic improvement and agronomy - Written by leading scientists from around the world with publication records of demonstrable influence and impact - Combines environment-specific cropping systems and general principles of crop science to appeal to advanced students and scientists in agriculture-related disciplines, from molecular sciences to natural resources management
Water Pollution Calculations: Quantifying Pollutant Formation, Transport, Transformation, Fate and Risks provides a comprehensive collection of relevant, real-world water pollution calculations. The book's author explains, in detail, how to measure and assess risks to human populations and ecosystems exposed to water pollutants. The text covers water pollution from a multivariate, systems approach, bringing in hydrogeological, climatological, meteorological processes, health and ecological impacts, and water and wastewater treatment and prevention.After first reviewing the physics, chemistry, and biology of water pollution, the author explores both groundwater and surface waters. This is followed by an in-depth look at water quality indicators, measurements, models, and water engineering. Groundwater remediation, risk assessment, and green engineering round out the text with forward-thinking ideas towards sustainability. This invaluable reference offers a practical tool for those needing a precise and applicable understanding of different types of water pollution calculations. - Includes applications of theory to real-world problems with personalized and customized examples of calculations to prepare exams, guidance documents, and correspondence - Walkthroughs and derivation of equations enhance knowledge so that complex water pollution concepts can be more easily grasped - Explains processes and mechanisms, providing an understanding of how pollutants are formed, transported, transformed, deposited, and stored in the environment
The chemistry of nanomaterials has developed considerably in the past two decades, and concepts that have emerged from these developments are now well established. The surface modification of nanoparticles is a subject of intense research interest given its importance for many applications across a number of disciplines. This comprehensive guide is the first to be devoted to the surface chemistry of inorganic nanocrystals. Following an introduction to the physical chemistry of surfaces, chapters cover topics such as the surface modification of nanoparticles, water compatible, polymer-based, and inorganic nanocomposites, as well as relevant applications in catalysis, biotechnology and nanomedicine. Highlighting recent advances, Surface Chemistry of Colloidal Nanocrystals provides an integrated approach to chemical aspects related to the surface of nanocrystals. Written by prestigious scientists, this will be a useful resource for students and researchers working in surface science, nanoscience and materials science as well as those interested in the applications of the nanomaterials in areas such as health science, biology, and environmental engineering.
A comprehensive overview of nanomaterials that are inspired by or targeted at biology, including some of the latest breakthrough research. Throughout, valuable contributions from top-level scientists illustrate how bionanomaterials could lead to novel devices or structures with unique properties. The first and second part cover the most relevant synthetic and bioinspired nanomaterials, including surfaces with extreme wettability properties, functional materials with improved adhesion or structural and functional systems based on the complex and hierarchical organization of natural composites. These lessons from nature are explored in the last section where bioinspired materials are proposed for biomedical applications, showing their potential for future applications in drug delivery, theragnosis, and regenerative medicine. A navigational guide aimed at advanced and specialist readers, while equally relevant for readers in research, academia or private companies focused on high added-value contributions. Young researchers will also find this an indispensable guide in choosing or continuing to work in this stimulating area, which involves a wide range of disciplines, including chemistry, physics, materials science and engineering, biology, and medicine.
The 1992 Parallel Architectures and Languages Europe conference continues the tradition - of a wide and representative international meeting of specialists from academia and industry in theory, design, and application of parallel computer systems - set by the previous PARLE conferences held in Eindhoven in 1987, 1989, and 1991. This volume contains the 52 regular and 25 poster papers that were selected from 187 submitted papers for presentation and publication. In addition, five invited lectures areincluded. The regular papers are organized into sections on: implementation of parallel programs, graph theory, architecture, optimal algorithms, graph theory and performance, parallel software components, data base optimization and modeling, data parallelism, formal methods, systolic approach, functional programming, fine grain parallelism, Prolog, data flow systems, network efficiency, parallel algorithms, cache systems, implementation of parallel languages, parallel scheduling in data base systems, semantic models, parallel data base machines, and language semantics.
This highly influential work--now in a revised and expanded third edition incorporating major advances in the field--gives clinicians, educators, and students a new understanding of what the mind is, how it grows, and how to promote healthy development and resilience. Daniel J. Siegel synthesizes cutting-edge research from multiple disciplines, revealing the ways in which neural processes are fundamentally shaped by interpersonal relationships throughout life. And even when early experiences are not optimal, building deeper connections to other people and to one's own internal experience remains a powerful resource for growth. Professors praise the book’s utility in courses from developmental psychology and child development to neuroscience and counseling. New to This Edition *Incorporates findings from a huge body of recent research; over 1,000 citations added. *Revisits and refines the core hypotheses of interpersonal neurobiology. *Chapter on the experience of belonging and the development of identity. *New or expanded discussions of behavioral epigenetics, the default mode network of the brain, social neuroscience, cultural and gender issues, theory of mind, the Wheel of Awareness contemplative practice, the science of consciousness, and more.
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. - Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them - Focused chapters on toxin applications and common properties or general features of toxins
Fundamentals of In Vivo Magnetic Resonance Authoritative reference explaining why and how the most important, radiation-free technique for elucidating tissue properties in the body works In Vivo Magnetic Resonance helps readers develop an understanding of the fundamental physical processes that take place inside the body that can be probed by magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), uniquely bridging the gap between the physics of magnetic resonance (MR) image formation and the in vivo processes that influence the detected signals, thereby equipping the reader with the mathematical tools essential to study the spin interactions leading to various contrast mechanisms. With a focus on clinical relevance, this book equips readers with practical knowledge that can be directly applied in medical settings, enabling informed decision-making and advancements in the field of medical imaging. The material arises from the lecture notes for a Stanford University Department of Radiology course taught for over 15 years. Aided by clever illustrations, the book takes a step-by-step approach to explain complex concepts in a comprehensible manner. Readers can test their understanding by working on approximately 60 sample problems. Written by two highly qualified authors with significant experience in the field, In Vivo Magnetic Resonance includes information on: The fundamental imaging equations of MRI Quantum elements of magnetic resonance, including linear vector spaces, Dirac notation, Hilbert Space, Liouville Space, and associated mathematical concepts Nuclear spins, covering external and internal interactions, chemical shifts, dipolar coupling, J-coupling, the spin density operator, and the product operator formalism In vivo MR spectroscopy methods MR relaxation theory and the underlying sources of image contrast accessible via modern clinical MR imaging techniques With comprehensive yet accessible coverage of the subject and a wealth of learning resources included throughout, In Vivo Magnetic Resonance is an ideal text for graduate students in the fields of physics, biophysics, biomedical physics, and materials science, along with lecturers seeking classroom aids.
The past two decades have seen transformative advances in cosmology and string theory. Observations of the cosmic microwave background have revealed strong evidence for inflationary expansion in the very early universe, while new insights about compactifications of string theory have led to a deeper understanding of inflation in a framework that unifies quantum mechanics and general relativity. Written by two of the leading researchers in the field, this complete and accessible volume provides a modern treatment of inflationary cosmology and its connections to string theory and elementary particle theory. After an up-to-date experimental summary, the authors present the foundations of effective field theory, string theory, and string compactifications, setting the stage for a detailed examination of models of inflation in string theory. Three appendices contain background material in geometry and cosmological perturbation theory, making this a self-contained resource for graduate students and researchers in string theory, cosmology, and related fields.
Artificial intelligence has already enabled pivotal advances in diverse fields, yet its impact on computer architecture has only just begun. In particular, recent work has explored broader application to the design, optimization, and simulation of computer architecture. Notably, machine-learning-based strategies often surpass prior state-of-the-art analytical, heuristic, and human-expert approaches. This book reviews the application of machine learning in system-wide simulation and run-time optimization, and in many individual components such as caches/memories, branch predictors, networks-on-chip, and GPUs. The book further analyzes current practice to highlight useful design strategies and identify areas for future work, based on optimized implementation strategies, opportune extensions to existing work, and ambitious long term possibilities. Taken together, these strategies and techniques present a promising future for increasingly automated computer architecture designs.
The rise of the Internet of Things (IoT) and Artificial Intelligence (AI) leads to the emergence of edge computing systems that push the training and deployment of AI models to the edge of networks for reduced bandwidth cost, improved responsiveness, and better privacy protection, allowing for the ubiquitous AI that can happen anywhere and anytime. Motivated by the above trend, this book introduces a new computing paradigm, the Social Edge Computing (SEC), that empowers human-centric edge intelligent applications by revolutionizing the computing, intelligence, and the training of the AI models at the edge. The SEC paradigm introduces a set of critical human-centric challenges such as the rational nature of edge device owners, pronounced heterogeneity of the edge devices, real-time AI at the edge, human and AI interaction, and the privacy of the edge users. The book addresses these challenges by presenting a series of principled models and systems that enable the confluence of the computing capabilities of devices and the domain knowledge of the people, while explicitly addressing the unique concerns and constraints from humans. Compared to existing books in the field of edge computing, the vision of this book is unique: we focus on the social edge computing (SEC), an emerging paradigm at the intersection of edge computing, AI, and social computing. This book discusses the unique vision, challenges and applications in SEC. To our knowledge, keeping humans in the loop of edge intelligence has not been systematically reviewed and studied in an existing book. The SEC vision generalizes the current machine-to-machine interactions in edge computing (e.g., mobile edge computing literature), and machine-to-AI interactions (e.g., edge intelligence literature) into a holistic human-machine-AI ecosystem.
Designed to cater to the needs of both novice and seasoned writing instructors, this book provides a range of practical and adaptable strategies for integrating generative artificial intelligence (AI) into English writing curricula. Generative AI in the English Composition Classroom proposes strategic methodologies to ensure that AI is utilized as a facilitator of learning and creativity, rather than as a shortcut to academic success. With a particular emphasis on sophisticated large language models such as Claude, ChatGPT, and Gemini, this book critically addresses potential challenges, including concerns related to academic integrity. It includes case studies and practical strategies to exemplify how AI can enhance the writing process while emphasizing the continuing importance of a solid foundation in writing structure, processes, and rhetorical strategies. These case studies and strategies are designed for immediate application, offering educators and students practical tools to effectively navigate AI-augmented writing environments. Finally, the book looks to the future, discussing the evolving skillsets required in the workforce and how educators can equip students for a future in which AI is an integral component. A forward-thinking and invaluable guide, this book will be of interest to educators involved in teaching English Composition and writing.
The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.
Robust statistics is the study of designing estimators that perform well even when the dataset significantly deviates from the idealized modeling assumptions, such as in the presence of model misspecification or adversarial outliers in the dataset. The classical statistical theory, dating back to pioneering works by Tukey and Huber, characterizes the information-theoretic limits of robust estimation for most common problems. A recent line of work in computer science gave the first computationally efficient robust estimators in high dimensions for a range of learning tasks. This reference text for graduate students, researchers, and professionals in machine learning theory, provides an overview of recent developments in algorithmic high-dimensional robust statistics, presenting the underlying ideas in a clear and unified manner, while leveraging new perspectives on the developed techniques to provide streamlined proofs of these results. The most basic and illustrative results are analyzed in each chapter, while more tangential developments are explored in the exercises.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.