The book considers the lot-sizing and scheduling problem for flexible flow line production facilities. Flexible flow lines are flow lines with parallel machines on some or all production stages. They can be found in a vast number of industries. A three-phased solution approach is presented that solves the integrated lot-sizing and scheduling problem in a hierarchical manner. The approach is able to handle several important features relevant in industrial practice, such as back-orders and setup carry-over. The developed solution procedures solve practically sized problems in a relatively short amount of time. One of the procedures is based on a novel mixed integer programming (MIP) model, which employs integer variables instead of binary variables. This makes it possible to find (near-)optimal solutions using standard algorithms such as CPLEX. Another procedure uses two nested Genetic Algorithms. An application of the framework in the semiconductor industry is given.
This book reviews the geochemical and petrological characteristics of potassic igneous rock complexes, and investigates the various tectonic settings in which these rocks occur. The authors provide an overview and classification of these rocks and elucidate the geochemical differences between barren and mineralized potassic igneous complexes. High-K rocks are genetically associated with a number of epithermal gold and porphyry copper-gold deposits. In recent years, there has also been growing recognition of an association of such rocks with iron-oxide copper-gold (IOCG) deposits, intrusion-related gold deposits (IRGDs) and Carlin-type gold deposits. This fifth updated and expanded edition incorporates new data and references from world-class copper and gold deposits worldwide. It also includes the latest publications on the petrogenesis of high-K magmatism and related mineral deposits. Numerous new representative ore photographs of the mineral deposits described are also included in the new edition. As such, the book offers a valuable guide not only for academic petrologists working on alkaline rocks, but also for exploration geologists prospecting for epithermal gold and/or porphyry copper-gold deposits in modern and ancient terrains.
The New York Times Best Historical Fiction of 2020 The Guardian's Best Fiction of 2020 Thrillist's Best Books of the Year Daniel Kehlmann transports the medieval legend of the trickster Tyll Ulenspiegel to the seventeenth century in an enchanting work of magical realism, macabre humor, and rollicking adventure. Tyll is a scrawny boy growing up in a quiet village until his father, a miller with a forbidden interest in alchemy and magic, is found out by the church. After Tyll flees with the baker’s daughter, he falls in with a traveling performer who teaches him his trade. As a juggler and a jester, Tyll forges his own path through a world devastated by the Thirty Years’ War, evading witch-hunters, escaping a collapsed mine outside a besieged city, and entertaining the exiled King and Queen of Bohemia along the way. The result is both a riveting story and a moving tribute to the power of art in the face of the senseless brutality of history. Translated from the German by Ross Benjamin
Metallic Mineral Resources: The Critical Components for a Sustainable Earth serves the increasing interest in metal resources, especially the critical and strategic metals which are essential commodities for the green energy transition. The opening chapters introduce the heterogeneous distribution of metal resources as well as the industrial use of metals. The main chapters then work systematically through abundant metal systems, scarce critical metal systems, rare critical metal systems, trace critical metal systems, and precious metal systems. The book wraps with a close examination of temporal distribution of mineral resources and an insightful discussion of the future of mineral resources. Researchers and engineers in economic geology and mining and exploration industries will find themselves returning to this key reference for years to come.• Describes how mineable and economic metal concentrations form and are preserved in the Earth's upper crust • Explores how they are discovered by systematic mineral exploration at a variety of scales • Discusses how to educate the public on the scarcity of natural metal resources and the issues concerning the nexus between the energy transition and potential exhaustion of critical metals
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. This extensive title, which combines scientific principles with up-to-date clinical procedures, has been thoroughly updated for the fourteenth edition. You’ll find in-depth material on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them.
This book investigates convex multistage stochastic programs whose objective and constraint functions exhibit a generalized nonconvex dependence on the random parameters. Although the classical Jensen and Edmundson-Madansky type bounds or their extensions are generally not available for such problems, tight bounds can systematically be constructed under mild regularity conditions. A distinct primal-dual symmetry property is revealed when the proposed bounding method is applied to linear stochastic programs. Exemplary applications are studied to assess the performance of the theoretical concepts in situations of practical relevance. It is shown how market power, lognormal stochastic processes, and risk-aversion can be properly handled in a stochastic programming framework. Numerical experiments show that the relative gap between the bounds can typically be reduced to a few percent at reasonable problem dimensions.
The book considers the lot-sizing and scheduling problem for flexible flow line production facilities. Flexible flow lines are flow lines with parallel machines on some or all production stages. They can be found in a vast number of industries. A three-phased solution approach is presented that solves the integrated lot-sizing and scheduling problem in a hierarchical manner. The approach is able to handle several important features relevant in industrial practice, such as back-orders and setup carry-over. The developed solution procedures solve practically sized problems in a relatively short amount of time. One of the procedures is based on a novel mixed integer programming (MIP) model, which employs integer variables instead of binary variables. This makes it possible to find (near-)optimal solutions using standard algorithms such as CPLEX. Another procedure uses two nested Genetic Algorithms. An application of the framework in the semiconductor industry is given.
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