This book introduces semantic representations of multiscale, multidomain physiological systems that link to qualitative reasoning and to quantitative analysis of biophysical processes in health and disease. Two major public health problems, diabetes and hypertension, serve as use-cases to illustrate the depth and rigor of such representations for logical inference and quantitative analysis. Central to this approach is the Ontology of Physics for Biology (OPB) that formally represents the foundations of classical physics and engineering system dynamics that are the basis for our understanding of biomedical entities, processes, and functional relationships. Furthermore, we introduce OPB-based software for annotating and abstracting available biosimulation models for reuse, recombination, and for archiving of physics-based biomedical knowledge. We have formalized and leveraged physics-based biological knowledge as a working view of physiology and biophysics from three distinct perspectives: (1) biologists and biomedical investigators, (2) biophysicists and bioengineers, and (3) biomedical ontologists and informaticists. We present a logical and intuitive semantics of classical physics as a tool for mediating and translating biophysical knowledge among biomedical domains. Daniel L. Cook, MD, PhD John H. Gennari, PhD Maxwell L. Neal, PhD
In 2005, beekeepers in the United States began observing a mysterious and disturbing phenomenon: once-healthy colonies of bees were suddenly collapsing, leaving behind empty hives full of honey and pollen. Over the following decade, widespread honeybee deaths—some of which have come to be called Colony Collapse Disorder (CCD)—have continued to bedevil beekeepers and threaten the agricultural industries that rely on bees for pollination. Scientists continue to debate the causes of CCD, yet there is no clear consensus on how to best solve the problem. Vanishing Bees takes us inside the debates over widespread honeybee deaths, introducing the various groups with a stake in solving the mystery of CCD, including beekeepers, entomologists, growers, agrichemical companies, and government regulators. Drawing from extensive interviews and first-hand observations, Sainath Suryanarayanan and Daniel Lee Kleinman examine how members of each group have acquired, disseminated, and evaluated knowledge about CCD. In addition, they explore the often-contentious interactions among different groups, detailing how they assert authority, gain trust, and build alliances. As it explores the contours of the CCD crisis, Vanishing Bees considers an equally urgent question: what happens when farmers, scientists, beekeepers, corporations, and federal agencies approach the problem from different vantage points and cannot see eye-to-eye? The answer may have profound consequences for every person who wants to keep fresh food on the table.
Master the latest medical and cosmetic procedures with Surgery of the Skin, the most comprehensive dermatological surgery resource available. Written from the surgeon's perspective, this medical reference book features step-by-step guidance on performing the most updated developments and cutting edge approaches across the entire spectrum of dermatologic surgery. - Improve surgical results and avoid pitfalls with expert, evidence-based guidance. - Stay on the cutting edge with in-depth step-by-step descriptions of tumescent vertical vector facelifts, blepharoplasty, composite grafts, Botox treatments, soft tissue augmentation, management of dysplastic nevi and melanoma, and more. - View immersive videos from an expanded library with more than 130 clips totaling over six hour's footage. - Explore brand-new chapters on rejuvenation of the female external genitalia; hidradenitis suppurativa; and photoaging-related mottled pigmentation. - Improve treatment outcomes for patients with skin of color and gain a truly global perspective of dermatologic surgery through an expanded contributor group of leading international experts. - Master how to perform cutting-edge techniques across the entire spectrum of dermatologic surgery, including botulinum toxins; fillers; cryosurgery; flaps; grafting; scar revisions; lasers; face-lift techniques; blepharoplasty techniques; Mohs surgery; and more. - Effectively manage a full range of complex disorders, such as vitiligo surgery, keloids, and leg ulcers, with a unique section devoted to these special procedures. - Easily visualize complex procedures and concepts with more than 1,000 illustrations, photos, and graphics. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
The aim of this work is to provide a fuller spectrum of information in a single source on enzyme-catalyzed reactions than is currently available in any published reference work or as part of any Internet database. The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods includes 20,000 review articles and seminal research papers. Additionally, it provides a novel treatment of so-called ATPase and GTPase reactions to account for the noncovalent substratelike and productlike states of molecular motors, elongation factors, transporters, DNA helicases, G-reulatory proteins, and other energases. - Includes a compendium of over 6,000 enzyme reactions (including enzyme commission numbers, alternative names, substrates, products, alternative substrates, and properties) - Covers over 900 chemical structures of key metabolites and cofactors - Index directs readers to the exact pages for over 9,500 enzyme names
In this study, Wu explores how the concepts honor, shame, and guilt function in the book of Ezekiel, as well as in the wider contexts of their general use in anthropological or social-scientific approaches to biblical studies. He frames Ezekiel’s key terms for honor (kabod), shame (bosh ), and guilt ('awah) within an analysis of a broad perspective on these terms in the body of the Old Testament as a way of forming the “concept spheres” within which the specific instances of each term in Ezekiel sit. Wu gleans insight from the dominant contemporary definitions of honor, shame, and guilt in the fields of psychology and anthropology and their application to biblical studies, and he reflects on how this broader context informs and is informed by his analysis of Ezekiel. The study concludes by drawing together the implications and contribution of the analysis of Ezekiel and applying them to the development of social-scientific models for the future.
Yahweh is the proper name of the biblical God. His early character is central to understanding the foundations of Jewish, Christian, and Islamic monotheism. As a deity, the name appears only in connection with the peoples of the Hebrew Bible, but long before Israel, the name is found in an Egyptian list as one group in the land of tent-dwellers, the Shasu. This is the starting-point for Daniel E. Fleming's sharply new approach to the god Yahweh. In his analysis, the Bible's 'people of Yahweh' serve as a clue to how one of the Bronze Age herding peoples of the inland Levant gave its name to a deity, initially outside of any relationship to Israel. For 150 years, the dominant paradigm for Yahweh's origin has envisioned borrowing from peoples of the desert south of Israel. Fleming argues in contrast that Yahweh was not taken from outsiders. Rather, this divine name is evidence for the diverse background of Israel itself.
Daniel W. McManigal provides a fresh analysis of the meaning of the baptism in the Holy Spirit and fire, and John's baptism as a prophetic sign-act. Expanding upon the sources, grammar and meaning of the Logion, analysing Old Testament and Second Temple texts, and discussing the prevalent theme of judgment in baptism, McManigal offers the first extended treatment of the baptism in the Holy Spirit in Matthew's gospel. As a backdrop for the prevalence of judgment in baptism, McManigal locates Matthew's eschatological judgment within the broader Old Testament and apocalyptic literature of the Second Temple, drawing upon texts such as Isaiah 11 and the Isaiah Targum, Malachi 3, Daniel 7, 1 Enoch and 4 Ezra. This volume's analysis aids deeper understanding of how the themes of the Old Testament are woven throughout Matthew's narrative, capitalizing on John's role as the last of the prophets sent to Israel; McManigal focuses in particular on Matthew's foretelling the coming of the Messiah, and his call for repentance in order to prepare people for the arrival of the kingdom of God. Drawing out the unique Matthean meaning of the baptism of the “coming one,” McManigal's study offers readers a new insight into the nature of repenting and prophetic baptism, whether through water, fire or Spirit.
The Legacy of Israel in Judah's Bible undertakes a comprehensive re-evaluation of the Bible's primary narrative in Genesis through Kings as it relates to history. It divides the core textual traditions along political lines that reveal deeply contrasting assumptions, an approach that places biblical controversies in dialogue with anthropologically informed archaeology. Starting from close study of selected biblical texts, the work moves toward historical issues that may be illuminated by both this material and a larger range of textual evidence. The result is a synthesis that breaks away from conventional lines of debate in matters relating to ancient Israel and the Bible, setting an agenda for future engagement of these fields with wider study of antiquity.
This book will help you to understand and appraise clinical research articles and guidelines and assess how they should influence your practice. Assuming no prior knowledge, Clinical Evidence Made Easy starts by explaining the theory of evidence-based practice, including: understanding the hierarchy of evidence how to recognize bias assessing research papers making sense of qualitative research making use of clinical guidelines what to do with evidence from pharmaceutical companies how to apply the evidence in real life. The book concludes with a section covering clinical evidence at work (completely updated for this new edition) which: provides you with simple appraisal tools that you can use to evaluate research papers and clinical guidance uses extracts from original journal articles to show how you can put the appraisal tools and theory into practice. This new edition has been thoroughly revised and updated, and now features ‘Test your understanding’ questions for each chapter, along with answers at the end of the book.
In 2010, U.S. special operations forces (SOF) in Afghanistan began a new and innovative program to fight the Taliban insurgency using the movement's structure and strategy against it. The Village Stability Operations/Afghan Local Police initiative consisted of U.S. Army Special Forces and U.S. Navy SEAL teams embedding with villagers to fight the Taliban holistically. By enlisting Afghans in their own defense, organizing the local populace, and addressing their grievances with the Afghan government, SOF was able to defeat the Taliban’s military as well as its political arm. Combining the traditions of U.S. Army Special Forces with the lessons learned in the broader SOF community from years of counterinsurgency work in Iraq and Afghanistan, this new approach fundamentally changed the terms of the conflict with the Taliban. However, little has been written about this initiative outside of the special operations community until now. In this first-hand account of how the Village Stability Operations program functioned, Daniel R. Green provides a long-term perspective on how SOF stabilized the southern Afghan province of Uruzgan, the site of the Pashtun uprising against the Taliban in 2001 led by Hamid Karzai, future president of Afghanistan. In the Warlords’ Shadow offers a comprehensive overview of how SOF adapted to the unique demands of the local insurgency and is a rare, inside look at how special operations confronted the Taliban by fighting a “better war” and in so doing fundamentally changed the course of the war in Afghanistan.
Aiming at building efficient radiology operations, this book walks the reader through the entire radiology workflow, from the moment that the examination is requested to the reporting of findings. Using their practical experience, the authors draw attention to the many elements that can go wrong at each step, and explain how critical analysis and objective metrics can be used to fix broken processes. Readers will learn how to measure the efficiency of their workflows, where to find relevant data, and how to use it in the most productive ways. The book also addresses how data can be turned into insightful operational information to produce organizational change. All aspects of radiology operations are considered including ordering, scheduling, protocols, checking-in, image acquisition, image interpretation, communication, and billing. The closing section provides a deeper dive into the advanced tools and techniques that are used to analyze operations, including queuing theory, process mining and artificial intelligence.
Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings. This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including: neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.
Topics in Behavioral Neurology and Neuropsychology provides information pertinent to neuropsychology and behavioral neurology. This book serves as a guide to those caring for patients with disorders of higher cortical function. Organized into 18 chapters, this book begins with an overview of the classes of disorders of higher cortical function according to major behavioral disturbance. This text then presents the various classification schemes for aphasic syndromes. Other chapters consider the multidimensional process of the analysis of various speech disorders, including dysprosody, dysarthria, hysteria, anomia, and aphasia. This book discusses as well the various forms of alexia, including pure alexia, alexia, alexia with agraphia, and frontal alexia. The final chapter deals with stroke and other brain disorders. This book is a valuable resource for neurologists, psychiatrists, neuroscientists, neuropsychologists, neurology residents, speech pathologists, and rehabilitation medicine specialists. Readers who are interested in the study of the disorders of the higher cortical function will also find this book useful.
The psychology of terrorism, in its most basic form, is about fear. The purposes of this book are to unpack the complexity of terrorism fears and to present a new paradigm for understanding the psychology of terrorism.
The world's leading reference in hematopathology returns with this completely updated second edition. Authored by international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant -- with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. Comprehensive in scope, it's a must-have resource for both residents and practicing pathologists alike. - Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue. - Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies. - Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images. - Boasts detailed, practical advice from world leaders in hematopathology. - Places an emphasis on pathologic diagnoses, including molecular and genetic testing. - Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and peripheral T-cell lymphomas. - Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. There's also a downloadable image bank, and Virtual Microscope Slides are featured in several chapters.
Biobased Surfactants: Synthesis, Properties, and Applications, Second Edition, covers biosurfactant synthesis and applications and demonstrates how to reduce manufacturing and purification costs, impurities, and by-products. Fully updated, this book covers surfactants in biomedical applications, detergents, personal care, food, pharmaceuticals, cosmetics, and nanotechnology. It reflects on the latest developments in biobased surfactant science and provides case scenarios to guide readers in efficient and effective biobased surfactant application, along with strategies for research into new applications. This book is written from a biorefinery-based perspective by an international team of experts and acts as a key text for researchers and practitioners involved in the synthesis, utilization, and development of biobased surfactants. - Describes new and emerging biobased surfactants and their synthesis and development - Showcases an interdisciplinary approach to the topic, featuring applications to chemistry, biotechnology, biomedicine, and other areas - Presents the entire lifecycle of biobased surfactants in detail
DIVThrough a study of industry publications over much of the century, shows how the U.S. children’s clothing industry produced increasingly refined categories of childhood./div
Many documentaries, articles, museum exhibits, books, and movies have now treated what became known as the Tuskegee Experiment involving the black pilots who gained fame during World War II as the Tuskegee Airmen. Most of these works have focused on the training of Americas first black fighter pilots and their subsequent accomplishments during combat. This publication goes further, using captioned photographs to trace the airmen through the stages of training, deployment, and combat actions in North Africa, Italy, and Germany, in an attractive coffee-table-book format. Included for the first time are depictions of the critical support roles of doctors, nurses, mechanics, navigators, weathermen, parachute riggers, and other personnel, all of whom contributed to the airmens success, and many of whom went on to help complete the establishment of the 477th Composite Group. The authors have told, in pictures and words, the full story of the Tuskegee Airmen and the environments in which they lived, worked, played, fought, and sometimes died.
H. Daniel Zacharias presents a literary-critical analysis of the Gospel of Matthew and its interaction with Davidic tradition and use of Davidic typology. Throughout the narrative, the evangelist makes pervasive use of Davidic tradition from the Old Testament in his portrayal of Jesus. This begins from the first verse and the declaration that Jesus is the Son of David, and culminates in Jesus' usage of Psalm 22's Davidic lament on the cross. Davidic material is present throughout Matthew, in allusion, in specific citations, in thematic material. In addition, Matthew makes use of Davidic typology numerous times, with David as type and Jesus as anti-type. Zacharias shows how the use of Davidic material presents to the reader a scripturally-grounded redefinition of what it means for Jesus to be the Son of David: not as a violent militant leader, as some expected, but as a physical descendant of David, a healing shepherd, and a humble king. Within the Gospel, Matthew utilizes Davidic typology to show how the Son of David even has similar experiences as his royal predecessor. Even David's own words from the psalms are utilized as testimony to the legitimacy of Jesus as the Davidic Messiah.
The eighth edition of The Evolution of Management Thought provides readers witha deep understanding of the origin and development of management ideas. Spanning an expansive time period, from the pre-industrial era to the modern age of globalization, this landmark volume examines the backgrounds, original work, and influences of major figures and their contributions to advances in management theory and practice. This fully-revised edition has been painstakingly reviewed and thoroughly updated to reflect areas of contemporary management such as job design, motivation, leadership, organization theory, technological change, and increased worker diversity. In this classic text, authors Daniel Wren and Arthur Bedeian examine the management challenges and perspectives of the Industrial Revolution, discuss the emergence of the management process and systematic management, trace the rise of scientific management, and much more. Organized around a chronological framework, the text places a comprehensive range of management theories in their historical context to clearly illustrate their evolution over time. The book’s four parts, each designed to be a self-contained unit of study, contain extensive cross-references to allow readers to connect earlier to later developments to the volume’s central unifying theme.
Metallic Mineral Resources: The Critical Components for a Sustainable Earth serves the increasing interest in metal resources, especially the critical and strategic metals which are essential commodities for the green energy transition. The opening chapters introduce the heterogeneous distribution of metal resources as well as the industrial use of metals. The main chapters then work systematically through abundant metal systems, scarce critical metal systems, rare critical metal systems, trace critical metal systems, and precious metal systems. The book wraps with a close examination of temporal distribution of mineral resources and an insightful discussion of the future of mineral resources. Researchers and engineers in economic geology and mining and exploration industries will find themselves returning to this key reference for years to come.• Describes how mineable and economic metal concentrations form and are preserved in the Earth's upper crust • Explores how they are discovered by systematic mineral exploration at a variety of scales • Discusses how to educate the public on the scarcity of natural metal resources and the issues concerning the nexus between the energy transition and potential exhaustion of critical metals
In Islands of Truth, Daniel Clayton examines a series of encounters with the Native peoples and territory of Vancouver Island in the late eighteenth and early nineteenth centuries. Although he focuses on a particular region and period, Clayton also meditates on how representations of land and people, and studies of the past, serve and shape specific interests, and how the dawn of Native-Western contact in this part of the world might be studied 200 years later, in the light of ongoing struggles between Natives and non-Natives over land and cultural status. Between the 1770s and 1850s, the Native people of Vancouver Island were engaged by three sets of forces that were of general importance in the history of Western overseas expansion: the West's scientific exploration of the world in the Age of Enlightenment; capitalist practices of exchange; and the geopolitics of nation-state rivalry. Islands of Truth discusses these developments, the geographies they worked through, and the stories about land, identity, and empire stemming from this period that have shaped understanding of British Columbia's past and present. Clayton questions premises underlying much of present B.C. historical writing, arguing that international literature offers more fruitful ways of framing local historical experiences. Islands of Truth is a timely, provocative, and vital contribution to post-colonial studies.
The evolution of the Canada–US borderland in the Pacific Northwest included the wholesale transformation of social organization and individual identities together with the redefinition and application of public power. Before and After the State examines the impact of those changes across a region that already harboured a vibrant, highly complex mélange of societies with dynamic local, regional, and global trade and kin networks. Allan McDougall, Lisa Philips, and Daniel Boxberger explore fundamental questions of state formation, social transformation, and the (re)construction of identity to expose the narratives and other devices of nation building, their impact on generations caught in the transition, and the reverberations of those national myths that continue to the present.
The genealogy of the French-speaking members of the Lewis and Clark expedition can often be traced back to the times where the fleur-de-lys was flying over New France. The terra incognita was explored to gratify Louis XIV's lust for the brown gold of the fur trade. By the time of the Lewis and Clark expedition, the French were well integrated into the North American population. These men were instrumental in the success of the Corps of Discovery. Observers from the Montreal North West Company spied on the expedition for fear of American encroachments. New Spain sent in vain a French adventurer to capture Meriwether Lewis. The legend of the West has both French and American heroes in common among the coureurs de bois (white Indians) and mountain men.
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