It’s an old question: Can a man and a woman just be colleagues, or friends, without taking it to the next level? It always starts innocently, an attraction that grows as they spend more time together. The couple enjoy each other’s company, and the connection builds and feelings develop. The anticipation grows, even if they are married. Decisions are made. What if the line is crossed? The excitement of being together is palatable. Sometimes temptation wins. Will couples stray and give up their promises to be with someone else? The big question is will it last, and was it worth the consequences? Are all the good ones taken? Do vows have an expiration date? Find out.
In companies that produce goods and services, productivity and efficiency improvements are a constant challenge. This book reviews the differences between productivity and efficiency. It proposes a new method and makes available a computational tool for implementation that contributes to facilitating the use of Data Envelopment Analysis (DEA). The book presents a discussion about productivity and efficiency, illustrating the potentials of use and conceptual differences. It covers the concepts and techniques for analysis of productivity and efficiency, analyzing critical benefits and limitations, explains in detail how to use DEA for analysis, provides innovative methods for using DEA, offers a free online computer tool with a direction guide, shows real empirical applications, and covers other techniques that can be used to complement the analysis performed. The book is for professionals, managers, consultants, students working and taking courses in productive systems of goods and services. Ancillary materials include a free online computer tool to operationalize the concepts and methods proposed in the book, a guide on how to use the method and the software developed for the DEA application. Solutions manual, instructor’s manual, PowerPoint slides, and figure slides also will be available upon qualified adoption.
New statistical methods and future directions of research in time series A Course in Time Series Analysis demonstrates how to build time series models for univariate and multivariate time series data. It brings together material previously available only in the professional literature and presents a unified view of the most advanced procedures available for time series model building. The authors begin with basic concepts in univariate time series, providing an up-to-date presentation of ARIMA models, including the Kalman filter, outlier analysis, automatic methods for building ARIMA models, and signal extraction. They then move on to advanced topics, focusing on heteroscedastic models, nonlinear time series models, Bayesian time series analysis, nonparametric time series analysis, and neural networks. Multivariate time series coverage includes presentations on vector ARMA models, cointegration, and multivariate linear systems. Special features include: Contributions from eleven of the worldâ??s leading figures in time series Shared balance between theory and application Exercise series sets Many real data examples Consistent style and clear, common notation in all contributions 60 helpful graphs and tables Requiring no previous knowledge of the subject, A Course in Time Series Analysis is an important reference and a highly useful resource for researchers and practitioners in statistics, economics, business, engineering, and environmental analysis. An Instructor's Manual presenting detailed solutions to all the problems in he book is available upon request from the Wiley editorial department.
Learn slang words, modern phrases, and curses they never taught you in German class with this handy and hilariously improper English-German phrasebook. You already know enough German to get by, but you want to be able to tell those inside jokes, greet your friends in a laid-back manner, and casually pick someone up at a bar. From “What’s up?” to “Wanna go home with me?” Dirty German will teach you how to speak like you're a regular on the streets of Berlin. But you’ll also discover material that goes beyond a traditional phrasebook, including: · Hilarious insults · Provocative facts · Explicit swear words · Themed German cocktails · And more Next time you’re traveling to Germany, pick up this book, drop the textbook formality, and get dirty!
The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.
Admiral Daniel V. Gallery boarded and captured a German U-Boat at sea in June, 1944—the first American officer to so capture an enemy warship since 1815! U-505 is Admiral Gallery’s own story of his extraordinary feat—and also a gripping narrative of the fierce Allied war against the German U-Boat fleet. “EXCELLENT.”—Chicago Tribune “Terrific...the first-hand story of Uncle Sam’s U-Boat killers.”—Chicago Daily News “Brimming with thrills.”—Philadelphia News “An engrossing tale...Pungent, entertaining, informative.”—Navy Times “A humdinger of a sea story...a highly readable book, trimmed from stem to stern with the writer’s irrepressible sense of humor.”—Chicago Sunday Times “Excellent in several ways: it provides a fine quick survey of the whole Atlantic war, it describes the operation of the German U-boat service, and, most dramatically, it tells how an American task force under Admiral Gallery achieved the unique feat of capturing a German submarine.”—Publishers’ Weekly “U-505 IS ONE OF THE WAR’S MOST EXCITING MEMOIRS.”—Chicago News “One of the best non-fiction books about World War II.”—Raleigh News & Observer “A first-rate adventure tale...suspense and excitement told with a seaman’s salty zest...excellent reading.”—Chicago Sunday Tribune “A masterful job that merits the attention of every lover of sea stories.”—Pittsburgh Press
Originally published in 1979, Solar Energy provides a tour of the world of solar energy and asks two key questions: is solar energy the key to the future of our energy needs, and what are the facts and potential of this source of renewable power. The book examines solar energy from the past, to modern plans for designing domestic solar housing, and looks at the sites and the technology applied to harness the Sun's power, such as the energy potential of windmills and the equatorial oceans. Behrman reports on the progress of scientists and manufacturers in making solar energy a viable competitor in the energy market, and studies the projections of a future energy crop for energy plantations.
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
Drinking a Hefeweizen at a Biergarten... Dancing at Berlin's hottest club... Cheering for the local soccer team at the Stadion... Drop the textbook formality and chat with the locals in Germany's everyday language. What's up? Wie geht's?; He/She is a real hottie. Er/Sie ist eine ganz hei±e Nummer.; What's on tap? Was gibt's vom Fass?; I ordered the Currywurst. Ich bin den Currywurst.; Do you wanna cuddle? Willst Du kuscheln?; Gooooooal! Toooooor!
The majority of empirical research in economics ignores the potential benefits of nonparametric methods, while the majority of advances in nonparametric theory ignores the problems faced in applied econometrics. This book helps bridge this gap between applied economists and theoretical nonparametric econometricians. It discusses in depth, and in terms that someone with only one year of graduate econometrics can understand, basic to advanced nonparametric methods. The analysis starts with density estimation and motivates the procedures through methods that should be familiar to the reader. It then moves on to kernel regression, estimation with discrete data, and advanced methods such as estimation with panel data and instrumental variables models. The book pays close attention to the issues that arise with programming, computing speed, and application. In each chapter, the methods discussed are applied to actual data, paying attention to presentation of results and potential pitfalls.
This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.
This text is intended for the sophomore level course in human variation/human biology taught in anthropology departments. It may also serve as a supplementary text in introductory physical anthropology courses. In addition to covering the standard topics for the course, it features contemporary topics in human biology such as the Human Genome Project, genetic engineering, the effects of stress, obesity and pollution.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. This extensive title, which combines scientific principles with up-to-date clinical procedures, has been thoroughly updated for the fourteenth edition. You’ll find in-depth material on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them.
A dense sheet of electrons accelerated to close to the speed of light can act as a tuneable mirror that can generate bright bursts of laser-like radiation in the short wavelength range simply via the reflection of a counter-propagating laser pulse. This thesis investigates the generation of such a relativistic electron mirror structure in a series of experiments accompanied by computer simulations. It is shown that such relativistic mirror can indeed be created from the interaction of a high-intensity laser pulse with a nanometer-scale, ultrathin foil. The reported work gives a intriguing insight into the complex dynamics of high-intensity laser-nanofoil interactions and constitutes a major step towards the development of a relativistic mirror, which could potentially generate bright burst of X-rays on a micro-scale.
GET D!RTY Next time you’re traveling or just chattin’ in German with your friends, drop the textbook formality and bust out with expressions they never teach you in school, including: •Cool slang •Funny insults •Explicit sex terms •Raw swear words Dirty German teaches the casual expressions heard every day on the streets of Germany: •What's up? Wie geht's? •I'm smashed. Ich bin total angeschickert. •Fuckin' Munich fans. Scheiß München Fans. •That shit reeks. Das riecht aber übel. •I wanna shag ass. Ich will abhauen. •What a complete asshole. Was für ein Arschloch. •Dude, you're built like Arnold! Mensch, du bist der Arnie!
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