Elgar Advanced Introductions are stimulating and thoughtful introductions to major fields in the social sciences and law, expertly written by the world’s leading scholars. This authoritative introduction provides a detailed overview of the complexities of the international intellectual property regime and the ways in which it operates. The authors cover the key international institutions and agreements that regulate and inform intellectual property at an international level such as the TRIPS Agreement, WIPO, WTO, the Paris Convention and the Berne Convention. The book serves as a platform to understand and contextualize policy discussions on topics such as public health, Internet regulation, as well as regional and bilateral trade treaties. Key features include: • Accessible and carefully summarized overview of the field • Comprehensive and up-to-date review of all major international intellectual property institutions and instruments • Introduces current issues within international IP negotiations • Provides tools to analyze the history and possible future development of international IP norms. Students, researchers, policy makers and practitioners of intellectual property will find this book to be an invaluable resource in gaining an understanding of the international rules and context in which both domestic and international IP policy issues should be understood.
Cognitive Narratives Thematics proposes a new way in which narrative works organise their thematic material. It rehabilitates the study of what books are about by providing a cognitive narrative thematic model (CNT). Part I presents CNT by combining different approaches to narrative, such as evolutionary theory, semiotics, possible worlds theory, or rhetorical criticism. Part II applies CNT to a variety of well-known narratives in different modalities, such as Robert Browning’s "My Last Duchess", Julia Donaldson’s The Gruffalo, Maurice Sendak’s Where the Wild Things Are, Frank Miller’s 300, or Mike Mignola’s Hellboy. It also considers literary histories and digital humanities. Daniel Candel shows that CNT deserves greater attention and that thematics generates its own forms and adds to the aesthetic pleasure of the text. Candel illustrates that CNT improves the established interpretations of the narrative works it studies. This innovative study reveals how CNT offers readers a deeper understanding, and how readers and critics are often using CNT intuitively without being aware of it. It is an invaluable resource for students and scholars of narrative theory.
Enables readers to understand applications of attribute-based encryption schemes in cloud computing with the support of blockchain technology With a focus on blockchain technology, Attribute-based Encryption (ABE) provides insight into the application of attribute-based encryption (ABE) schemes with blockchain, discussing types of blockchains, fundamentals of blockchain, and how blockchains are constructed. Comprised of 16 chapters, the text provides readers with an overview of the components that go into creating a dual ABE system of encryption proofs within the following: composite bilinear groups, dual pairing vector space framework, matrix pairing framework, framework for matrix pairing, and the application of cryptographic scheme on blockchain. The team of authors discuss the basic construction components of ABE and share the security models, including the selective and semi-adaptive security models, applying these to either prime order or composite order groups. This book also discusses the tools used for converting a composite order ABE scheme to prime order and an adaptive secure ABE scheme based on prime order. In Attribute-based Encryption (ABE), readers can expect to find information on: Mathematical background of ABE, covering group and cyclic group, elliptic curves, curve selection, supersingular curves, ordinary curves, and weil and tate pairing Basic construction components of ABE, covering access structure, monotone boolean formula, linear secret-sharing scheme, and ordered binary decision diagram Tools for converting composite order ABE schemes to prime order, covering security assumptions and conversion based on vectors for preliminaries, scheme construction, and security proof technique Foundations of blockchain technology, covering blocks, miners, hash functions, and public key cryptography Attribute-based Encryption (ABE) is an essential resource for professionals working in the field of design and cybersecurity who wish to understand how to use blockchain and the ABE scheme to provide fine-grained access control in outsourced data on third-party cloud servers.
The evolution of the Canada–US borderland in the Pacific Northwest included the wholesale transformation of social organization and individual identities together with the redefinition and application of public power. Before and After the State examines the impact of those changes across a region that already harboured a vibrant, highly complex mélange of societies with dynamic local, regional, and global trade and kin networks. Allan McDougall, Lisa Philips, and Daniel Boxberger explore fundamental questions of state formation, social transformation, and the (re)construction of identity to expose the narratives and other devices of nation building, their impact on generations caught in the transition, and the reverberations of those national myths that continue to the present.
These lecture notes deal with the problem of collective coordinates in many-body systems, which are treated as gauge systems in (0+1) dimensions. The resulting classical Dirac brackets are discussed, as well as the structure of the quantal space of wavefunctions. Emphasis is made on the application of the BRST formalism. Several systems displaying an approximate breakdown of symmetries are treated. Many-body physicists may find attractive both a rigorous formulation of the problem of collective coordinates and being introduced to the BRST formalism, which has become a fundamental tool in gauge theories. Field-theorists may find illuminating the applications to simpler mechanical examples. The notes are self-contained. In particular, they do not require a previous knowledge of either the BRST formalism or of collective transformations.
Environmental Systems Science: Theory and Practical Applications looks at pollution and environmental quality from a systems perspective. Credible human and ecological risk estimation and prediction methods are described, including life cycle assessment, feasibility studies, pollution control decision tools, and approaches to determine adverse outcome pathways, fate and transport, sampling and analysis, and cost-effectiveness. The book brings translational science to environmental quality, applying groundbreaking methodologies like informatics, data mining, and applications of secondary data systems. Multiple human and ecological variables are introduced and integrated to support calculations that aid environmental and public health decision making. The book bridges the perspectives of scientists, engineers, and other professionals working in numerous environmental and public health fields addressing problems like toxic substances, deforestation, climate change, and loss of biological diversity, recommending sustainable solutions to these and other seemingly intractable environmental problems. The causal agents discussed include physical, chemical, and biological agents, such as per- and polyfluoroalkyl substances (PFAS), SARS-CoV-2 (the COVID-19 virus), and other emerging contaminants. - Provides an optimistic and interdisciplinary approach, underpinned by scientific first principles and theory to evaluate pollutant sources and sinks, applying biochemodynamic methods, measurements and models - Deconstructs prior initiatives in environmental assessment and management using an interdisciplinary approach to evaluate what has worked and why - Lays out a holistic understanding of the real impact of human activities on the current state of pollution, linking the physical sciences and engineering with socioeconomic, cultural perspectives, and environmental justice - Takes a life cycle view of human and ecological systems, from the molecular to the planetary scale, integrating theories and tools from various disciplines to assess the current and projected states of environmental quality - Explains the elements of risk, reliability and resilience of built and natural systems, including discussions of toxicology, sustainability, and human-pollutant interactions based on spatial, biological, and human activity information, i.e. the exposome
Cet ouvrage rassemble les contributions consacrées au droit d’auteur à l’ère du numérique et présentées lors de la Journée de Droit de la Propriété Intellectuelle (www.jdpi.ch) organisée le 22 février 2017 à l’Université de Genève. Ces contributions sont: Blocage de sites web en droit suisse : des injonctions civiles et administratives de blocage au séquestre pénal (Yaniv Benhamou) ; Website Blocking Injunctions-a decade of development (Jo Oliver/Elena Blobel) ; Le marché numérique européen : enseignements de la jurisprudence de la Cour de justice et perspectives règlementaires (Jean-Michel Bruguière) ; User-generated Content and Other Digital Copyright Challenges: A North American Perspective (Ysolde Gendreau) ; Copyright in the Digital Age: A view from Asia (Wenwei Guan) ; Deep Copyright: Up - and Downstream Questions Related to Artificial Intelligence (AI) and Machine Learning (ML) (Daniel Schoenberger).
In this first book-length treatment of Descartes' important and influential natural philosophy, Daniel Garber is principally concerned with Descartes' accounts of matter and motion—the joint between Descartes' philosophical and scientific interests. These accounts constitute the point at which the metaphysical doctrines on God, the soul, and body, developed in writings like the Meditations, give rise to physical conclusions regarding atoms, vacua, and the laws that matter in motion must obey. Garber achieves a philosophically rigorous reading of Descartes that is sensitive to the historical and intellectual context in which he wrote. What emerges is a novel view of this familiar figure, at once unexpected and truer to the historical Descartes. The book begins with a discussion of Descartes' intellectual development and the larger project that frames his natural philosophy, the complete reform of all the sciences. After this introduction Garber thoroughly examines various aspects of Descartes' physics: the notion of body and its identification with extension; Descartes' rejection of the substantial forms of the scholastics; his relation to the atomistic tradition of atoms and the void; the concept of motion and the laws of motion, including Descartes' conservation principle, his laws of the persistence of motion, and his collision law; and the grounding of his laws in God.
Now more streamlined and focused than ever before, the 6th edition of CT and MRI of the Whole Body is a definitive reference that provides you with an enhanced understanding of advances in CT and MR imaging, delivered by a new team of international associate editors. Perfect for radiologists who need a comprehensive reference while working on difficult cases, it presents a complete yet concise overview of imaging applications, findings, and interpretation in every anatomic area. The new edition of this classic reference — released in its 40th year in print — is a must-have resource, now brought fully up to date for today's radiology practice. - Includes both MR and CT imaging applications, allowing you to view correlated images for all areas of the body. - Coverage of interventional procedures helps you apply image-guided techniques. - Includes clinical manifestations of each disease with cancer staging integrated throughout. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. - Over 5,200 high quality CT, MR, and hybrid technology images in one definitive reference. - For the radiologist who needs information on the latest cutting-edge techniques in rapidly changing imaging technologies, such as CT, MRI, and PET/CT, and for the resident who needs a comprehensive resource that gives a broad overview of CT and MRI capabilities. - Brand-new team of new international associate editors provides a unique global perspective on the use of CT and MRI across the world. - Completely revised in a new, more succinct presentation without redundancies for faster access to critical content. - Vastly expanded section on new MRI and CT technology keeps you current with continuously evolving innovations.
Employing a lively and accessible writing style, author Daniel W. Barrett integrates up-to-date coverage of social psychology’s core theories, concepts, and research with a discussion of emerging developments in the field—including social neuroscience and the social psychology of happiness, religion, and sustainability. Social Psychology: Core Concepts and Emerging Trends presents engaging examples, Applying Social Psychology sections, and a wealth of pedagogical features to help readers cultivate a deep understanding of the causes of social behavior.
Proceedings of the European Association for the Study of the Liver, Paris, September 1993. This conference was attended by leading world specialists, who gave papers on the advances made in the treatment of hepatitis B and C, benign tumours of the liver, lesions produced by medical treatment, and liver transplants. This book, which has a strong clinical focus, gives hepatologists and gastroenterologists the opportunity to provide a rapid overview of the most innovative work described by the major international research teams.
A comprehensive overview of nanomaterials that are inspired by or targeted at biology, including some of the latest breakthrough research. Throughout, valuable contributions from top-level scientists illustrate how bionanomaterials could lead to novel devices or structures with unique properties. The first and second part cover the most relevant synthetic and bioinspired nanomaterials, including surfaces with extreme wettability properties, functional materials with improved adhesion or structural and functional systems based on the complex and hierarchical organization of natural composites. These lessons from nature are explored in the last section where bioinspired materials are proposed for biomedical applications, showing their potential for future applications in drug delivery, theragnosis, and regenerative medicine. A navigational guide aimed at advanced and specialist readers, while equally relevant for readers in research, academia or private companies focused on high added-value contributions. Young researchers will also find this an indispensable guide in choosing or continuing to work in this stimulating area, which involves a wide range of disciplines, including chemistry, physics, materials science and engineering, biology, and medicine.
Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.
This book addresses the challenge of understanding human life. It compares our life experience with the attempts to grasp it by astrologers, eugenicists, psychologists, neuroscientists, social scientists, and philosophers. The main opposition among these specialties lies between understanding and misunderstanding. The book also addresses the central methodological difficulty of capturing a human life. It is first examined how certain approaches may lead to a misunderstanding of human life. The book contrasts the example of astrology—an accepted practice in ancient civilizations, but now classified among the pseudosciences—with astronomy, a full-fledged science since Galileo’s time. Another, more recent approach regards human life as predetermined by genes: the methods used by eugenicists, and later by political regimes under the name of hereditarianism, came to compete with genetics. A broader analysis shows how astrology and eugenicism are not truly scientific approaches. Next, the book looks at the ways of capturing an imaginary or real human life story. A comprehensive approach will try to fully understand their complexity, while a more explanatory approach considers only certain specific phenomena of human life. For example, demography studies only births, deaths, and migration. Another crucial factor in the collection of life histories is memory and its transmission. Psychology and psychoanalysis have developed different schools to try to explain them. The book concludes with a detailed discussion of the concepts and tools that have been proposed in more recent times for understanding the various aspects of life stories: mechanisms, systems, hermeneutics, and autonomy.
This issue of Hematology/Oncology Clinics will focus on lung cancer; specifically, Genomics in lung cancer; Neoadjuvant and adjuvant therapy for NSCLC; Treatment of locally advanced NSCLC; First line systemic therapy for NSCLC; Second line chemotherapy and beyond for NSCLC; Treatment of EGFR mutant tumors; Treatment of ALK positive tumors; New targets in NSCLC; Immunotherapy; Advances in Small cell lung cancer; and many more!
The world's leading reference in hematopathology returns with this completely updated second edition. Authored by international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant -- with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. Comprehensive in scope, it's a must-have resource for both residents and practicing pathologists alike. - Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue. - Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies. - Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images. - Boasts detailed, practical advice from world leaders in hematopathology. - Places an emphasis on pathologic diagnoses, including molecular and genetic testing. - Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and peripheral T-cell lymphomas. - Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. There's also a downloadable image bank, and Virtual Microscope Slides are featured in several chapters.
Child and Adolescent Development for Educators covers development from early childhood through high school. This text provides authentic, research-based strategies and guidelines for the classroom, helping future teachers to create an environment that promotes optimal development in children. The authors apply child development concepts to topics of high interest and relevance to teachers, including classroom discipline, constructivism, social-emotional development, and many others. Child and Adolescent Development for Educators combines the core theory with practical implications for educational contexts, and shows how child development links to the Australian Professional Standards for Graduate Teachers. Case studies and real-world vignettes further bridge the distance between research and the classroom. Along with strong coverage of key local research such as the Longitudinal Study of Australian Children and Longitudinal Study of Indigenous children.
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. - Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them - Focused chapters on toxin applications and common properties or general features of toxins
Once there were princes and peasants and very few between. The extremes of wealth and poverty are still with us, but that shouldn't blind us to the fact our societies have been utterly transformed for the better over the past century. As Daniel Waldenström makes clear in this authoritative account of wealth accumulation and inequality in the modern west, we are today both significantly richer and more equal. Using cutting-edge research and new, sometimes surprising, data, Waldenström shows that what stands out since the late 1800s is a massive rise in the size of the middle class and its share of society’s total wealth. Unfettered capitalism, it seems, doesn’t have to lead to boundless inequality. The key to progress was political and institutional change that enabled citizens to become educated, better paid, and to amass wealth through housing and pension savings. Waldenström asks how we can consolidate these gains while encouraging the creation of new capital. The answer, he argues, is to pursue tax and social policies that raise the wealth of people in the bottom and middle rather than cutting wealth of entrepreneurs at the top. Richer and More Equal is a benchmark account of one of the most profound and encouraging social changes in human history and a blueprint for continued progress.
Explores the pivotal Stones River Campaign of 1862-1863, detailing the intense battles and firsthand accounts that turned the tide for the Union Army. The waning days of 1862 marked a nadir in the fortunes of the Union. After major defeats at Fredericksburg in Virginia and Chickasaw Bayou in Mississippi, it fell to Maj. Gen. William S. Rosecrans and his Army of the Cumberland to secure a victory that would give military teeth to the Emancipation Proclamation set to take effect on January 1, 1863. Rosecrans moved his army out of Nashville on the day after Christmas to Murfreesboro, met Gen. Braxton Bragg’s Army of Tennessee, and fought one of the largest and bloodiest battles of the war. The full campaign, with extensive new material and coverage, is the subject of Daniel Masters’ new Hell by the Acre: A Narrative History of the Stones River Campaign, November 1862-January 1863. The opposing armies, 44,000 men under Rosecrans and 37,000 under Bragg, locked bayonets on December 31, 1862, in some of the hardest fighting of the war. Bragg’s initial attack drove the Federals back nearly three miles, captured 29 cannons, and thousands of prisoners. Somehow the Union lines held firm during the critical fighting along the Nashville Pike that afternoon against repeated determined attacks that left both armies bloodied and exhausted. The decisive moment came two days later when, in the fading afternoon of January 2, 1863, Bragg launched an assault on an isolated Union division on the east bank of Stones River. Once again, the Confederates enjoyed initial success only to be repulsed by 58 Union guns arrayed along the west bank and a daring counterattack. This repulse broke Bragg’s hold on Murfreesboro. He retreated the following night, leaving Rosecrans and his army victors of the field. Stones River was the quintessential soldiers’ battle. Prior books focus more on the generalship and high-level commands than the often-forgotten men in the ranks. Masters constructed his study from the ground up by focusing on the experiences of the front-line troops through hundreds of archival and firsthand accounts, many of which have never been published. Hell by the Acre is an unparalleled soldier’s view of Civil War combat and tactical command. Stones River marked a turning point for Federal fortunes in the Western Theater, and this fresh and original study sets forth the hefty cost of securing that victory for the Union.
This book introduces students to cultural anthropology with an emphasis on environmental and evolutionary approaches, focusing on how humans adapt to their environment and how the environment shapes culture. It shows how cultures evolve within the context of people’s strategies for surviving and thriving in their environments.This approach is widely used among scholars as a cross-disciplinary tool that rewards students with valuable insights into contemporary developments. Drawing on anthropological case studies, the authors address immediate human concerns such as the costs and consequences of human energy requirements, environmental change and degradation, population pressure, social and economic equity, and planned and unplanned change. Impacts of increasingly rapid climatic change on equitable access to resources and issues of human rights are discussed throughout. Towards the end of the book the student is drawn into a challenging thought experiment addressing the possible impacts of climatic warming on Middle America in the year 2040. All chapters conclude with "Summary," "Key Terms," and "Suggested Readings." This book is an ideal text for students of introductory anthropology and archaeology, environmental studies, world history, and human and cultural ecology courses.
This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Controversies in Oral and Maxillofacial Surgery, and is edited by Drs. Luis Vega and Daniel Meara. Articles will include: Controversies in Dentoalveolar and Preprosthetic Surgery; Controversies in Maxillofacial Trauma; Controversies in Traditional Maxillofacial Reconstruction; Controversies in Microvascular Maxillofacial Reconstruction; Controversies in TMJ Surgery; Controversies in Orthognathic Surgery; Controversies in Facial Cosmetics; Controversies in Cleft/Craniofacial Surgery; Controversies in Oral and Maxillofacial Infections; Controversies in Oral and Maxillofacial Pathology; Controversies in Oral and Maxillofacial Oncology; Controversies in Obstructive Sleep Apnea Surgery; Controversies in Oral and Maxillofacial Anesthesia; Controversies in Dental Implant Surgery; and more!
With the 13th edition, Wintrobe’s Clinical Hematology once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the peripheral blood smear, bone marrow, lymph nodes, and other tissues. With the knowledge about gene therapy and immunotherapy expanding, new, up-to-date information about the process and application of these therapies is included. Likewise, the editors have completely revised material on stem cell transplantation in regards to both malignant and benign disorders, graft versus host disease, and the importance of long-term follow-up of transplantation survivors.
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