This second edition offers an expanded and updated history of the field of fetal and neonatal development, allowing readers to gain a comprehensive understanding of the biological aspects that contribute to the wellbeing or pathophysiology of newborns. In this concluding opus of a long and prominent career as a clinical scientist, Dr. Longo has invited new contributions from noted colleagues with expertise in various fields to provide a historical perspective on the impact of how modern concepts emerged in the field of fetal physiology and contributed to the current attention paid to the fetal origins of diseases in adults. In addition to new chapters on maternal physiology and complications during pregnancy, others trace the history of the Society for Reproductive Investigation, governmental funding of perinatal research, and major initiatives to support training in the new discipline of maternal fetal medicine, including the Reproductive Scientist Development program. The extensive survey provided by the author, who personally knew most of the pioneers in the field, offers a unique guide for all clinical and basic scientists interested in the history of – and future approaches to diagnosing and treating – pathologies that represent the leading causes of neonatal mortality and, far too often, life-long morbidity.
This book presents the most comprehensive model yet for describing the structure and functioning of running freshwater ecosystems. Riverine Ecosystems Synthesis (RES) is a result of combining several theories published in recent decades, dealing with aquatic and terrestrial systems. New analyses are fused with a variety of new perspectives on how river network ecosystems are structured and function, and how they change along longitudinal, lateral, and temporal dimensions. Among these novel perspectives is a dramatically new view of the role of hydrogeomorphic forces in forming functional process zones from headwaters to the mouths of great rivers. Designed as a useful tool for aquatic scientists worldwide whether they work on small streams or great rivers and in forested or semi-arid regions, this book will provide a means for scientists to understand the fundamental and applied aspects of rivers in general and includes a practical guide and protocols for analyzing individual rivers. Specific examples of rivers in at least four continents (Africa, Australia, Europe and North America) serve to illustrate the power and utility of the RES concept. - Develops the classic, seminal article in River Research and Applications, "A Model of Biocomplexity in River Networks Across Space and Time" which introduced the RES concept for the first time - A guide to the practical analysis of individual rivers, extending its use from pristine ecosystems to modern, human-modified rivers - An essential aid both to the study fundamental and applied aspects of rivers, such as rehabilitation, management, monitoring, assessment, and flow manipulation of networks
The purpose of this book is to provide comprehensive coverage and an update of the major roles of eicosanoids in reproduction. It presents considerable evidence of the importance of lipoxygenase metabolites of arachidonic acid metabolism in reproductive processes. This interesting volume embraces a multidisciplinary approach to research in reproduction (biochemistry, endocrinology, physiology, pharmacology, etc.) at all levels, from whole animal studies through organ, cellular, and molecular approaches. This one-of-a-kind work provides several clinically relevant chapters and places emphasis on the relevance to human reproduction, when applicable. This text is an excellent update for researchers and clinicians on the current state of knowledge of the role of eicosanoids in mechanisms critical for successful reproductive function. This informative, easy-to-read resource is also useful to all those with a more specific interest in obstetrics, gynecology, clinical endocrinology, and the study of fertility.
Intended for cell biologists, biophysicists, biochemists, molecular biologists, physiologists, researchers in hemostatsis and thrombosis and pathologists, this book provides an insight into cell adhesion from three interdisciplinary perspectives: fundamental facts of adhesion; molecular biochemistry of adhesion and physiological aspects. It summarizes the basic aspects of surfaces in general and describes the theoretical and experimental tools necessary to investigate cell adhesion, including the basic biochemistry and molecular biology of adhesion. The book offers concise treatment of individual topics, features current material, and provides key references as a guide to further study.
In your practice, you require advanced knowledge of the obstetrical, medical, genetic and surgical complications of pregnancy and their effects on the mother and fetus. With both basic science and clinical information, six new chapters, and an updated color design, you need look no further than the 6th edition of this long-time best seller. Includes both basic science and clinical information to give you comprehensive knowledge of the biology of pregnancy. Acts as an excellent resource for OB/GYNs studying for their Maternal-Fetal Medicine boards — and for practitioners who need quick access to practical information. Provides an updated and focused reference list to keep you up to date on the standards of care in maternal-fetal medicine today. Keeps you current with a new section: Disorders at the Maternal-Fetal Interface...and 6 new chapters: Biology of Parturition, Developmental Origins of Health and Disease, Intrapartum Assessment of Fetal Health, Pathogenesis of Pre-term Birth, Maternal and Fetal Infectious Disorders, and Benign Gynecological Conditions of Pregnancy. Features over 50% new authorship with increased focus on international perspectives. Includes the following hot topics in Maternal-Fetal Medicine: o Biology of Parturition o Fetal Growth o Prenatal Genetic Screening and Diagnosis o Fetal Cardiac Malformations and Arrhythmias o Thyroid Disease and Pregnancy o Management of Depression and Psychoses during Pregnancy and the Puerperium Focuses on evidence based medicine, the current best practice in MFM for diagnosing and treating high risk pregnancies. Includes new illustrations and an updated, color design.
Comprehensive, user-friendly, and up to date, Chestnut's Obstetric Anesthesia: Principles and Practice, 6th Edition, provides the authoritative clinical information you need to provide optimal care to your patients. This substantially revised edition keeps you current on everything from basic science to anesthesia techniques to complications, including coverage of new research that is paving the way for improved patient outcomes. An expert editorial team ensures that this edition remains a must-have resource for obstetric anesthesiologists and obstetricians, nurse anesthetists and anesthesiology assistants, and anesthesiology and obstetric residents and students. - Presents the latest information on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy, emphasizing the treatment of the fetus and the mother as separate patients with distinct needs. - Contains new chapters on shared decision-making in obstetric anesthesia and chronic pain during and after pregnancy. - Features extensive revisions from cover to cover, including consolidated information on maternal infection and postoperative analgesia. - Covers key topics such as neonatal assessment and resuscitation, pharmacology during pregnancy and lactation, use of nitrous oxide for labor analgesia, programmed intermittent epidural bolus (PIEB) technique, epidural analgesia-associated fever, the role of gastric ultrasonography to assess the risk of aspiration, sugammadex in obstetric anesthesia, the role of video laryngoscopy and new supraglottic airway devices, spinal dysraphism, and cardiac arrest in obstetric patients. - Incorporates the latest guidelines on congenital heart disease and the management of sepsis, as well as difficult airway guidelines that are specific to obstetric anesthesia practice. - Offers abundant figures, tables, and boxes that illustrate the step-by-step management of a full range of clinical scenarios. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. - First edition won Best Book in Medical Science Award from the Association of American Publishers - Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias - A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references
Edited and authored by some of the most respected figures in the field, this newly revised book is your comprehensive guide to all areas of urogynecology, including urinary and fecal incontinence, urodynamic testing, management of genuine stress incontinence, pelvic organ prolapse, overactive bladder, and much more. Uniquely organized to reflect a physician's decision-making process, this practical, clinically oriented text moves from basic concepts through to clinical and urodynamic evaluation, management, and treatment. Inside, you'll find evidence-based assessments of appropriate therapies, along with algorithmic approaches to common complaints, and clear surgical illustrations. Exclusive to the third edition is a section addressing painful and irritative voiding disorders, including overactive bladder, as well as 20 new case presentations that offer opinions from the leading experts in urogynecology and urology. Features step-by-step instructions for urodynamic testing. Addresses all urogynecologic disorders, including genuine stress incontinence · pelvic organ prolapse · defecation disorders · painful and irritative voiding disorders · and specific conditions such as urinary tract infection. Presents vital information on urethral injections, covering the newest treatment options available. Examines the use of autologous materials and mesh in reconstructive pelvic surgery. Uses over 300 crisp illustrations to illuminate every detail. Contains a new section on painful and irritative voiding disorders, including a discussion of overactive bladder and the latest treatment options available. Discusses urodynamics and the most up-to-date testing available for urethral sphincteric function. Features 20 all new case presentations with expert commentary.
Knowledge of plant toxicity has always been important, but the information has not always been reliable. Now, increasing international trade is drawing attention to the inadequacy of regional information and highlighting the geographical fragmentation and notorious discrepancies of thinly documented information. The international community of safet
The past 50 years have seen an abundance of research on retirement planning and longevity risk. Reviewed here is the academic side of the research and its varied viewpoints and nuances. The evolution of retirement risk models, retirement portfolio problems and solutions, and annuities are some of the many topics covered.
Minimize complications with Creasy and Resnik's Maternal-Fetal Medicine. This medical reference book puts the most recent advances in basic science, clinical diagnosis, and management at your fingertips, equipping you with the up-to date evidence-based guidelines and knowledge you need to ensure the best possible outcomes in maternal-fetal medicine. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Apply today’s best practices in maternal-fetal medicine with an increased emphasis on evidence-based medicine. Find dependable, state-of-the-art answers to any clinical question with comprehensive coverage of maternal-fetal medicine from the foremost researchers and practitioners in obstetrics, gynecology and perinatology. Take advantage of the most recent diagnostic advances with a new section on Obstetrical Imaging, complemented by online ultrasound clips as well as cross references and links to genetic disorder databases. Stay on top of rapidly evolving maternal-fetal medicine through new chapters on Recurrent Spontaneous Abortion, Stillbirth, Patient Safety, Maternal Mortality, and Substance Abuse, as well as comprehensive updates on the biology of parturition, fetal DNA testing from maternal blood, fetal growth, prenatal genetic screening and diagnosis, fetal cardiac malformations and arrhythmias, thyroid disease and pregnancy, management of depression and psychoses during pregnancy and the puerperium, and much more. Access the complete contents online at Expert Consult.
Minimize complications with Creasy and Resnik's Maternal-Fetal Medicine.This medical reference book puts the most recent advances in basic science, clinical diagnosis, and management at your fingertips, equipping you with the up-to date evidence-based guidelines and knowledge you need to ensure the best possible outcomes in maternal-fetal medicine. "... Creasy & Resnik's Maternal-Fetal Medicine: Principles and Practice remains an authoritative reference book for clinical residents, fellows and practicing specialists in Maternal-Fetal Medicine." Reviewed by Ganesh Acharya , Feb 2015 Apply today's best practices in maternal-fetal medicine with an increased emphasis on evidence-based medicine. Find dependable, state-of-the-art answers to any clinical question with comprehensive coverage of maternal-fetal medicine from the foremost researchers and practitioners in obstetrics, gynecology and perinatology. Take advantage of the most recent diagnostic advances with a new section on Obstetrical Imaging, complemented by online ultrasound clips as well as cross references and links to genetic disorder databases. Stay on top of rapidly evolving maternal-fetal medicine through new chapters on Recurrent Spontaneous Abortion, Stillbirth, Patient Safety, Maternal Mortality, and Substance Abuse, as well as comprehensive updates on the biology of parturition, fetal DNA testing from maternal blood, fetal growth, prenatal genetic screening and diagnosis, fetal cardiac malformations and arrhythmias, thyroid disease and pregnancy, management of depression and psychoses during pregnancy and the puerperium, and much more. Access the complete contents online at Expert Consult. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
A single source of much of the information that doctors and other health care workers need in order to learn if a birth defect or genetic condition can be diagnosed prenatally." -- American Journal of Human Genetics
Explaining the practical implications of new discoveries in 'life-course biology', Nutrition and Lifestyle for Pregnancy and Breastfeeding is an informed resource on factors that affect offspring development. The impact of parental lifestyle and behavioural choices influence not only fetal development and birth outcomes, but also postnatal development, yet guidance on appropriate diet, behaviour, and exposures during pregnancy is often confusing and contradictory. With accessible explanations of the latest scientific research, and clear summaries and recommendations, this book is a valuable and authoritative guide for all levels of health care providers. The authors provide an overview of the background evidence, highlighting the importance of lifestyle choices prior to and during pregnancy. In-depth discussions of nutritional and lifestyle factors that impact on pregnancy and offspring outcomes are based on the latest research and exploration of key scientific studies. Nutrition and Lifestyle for Pregnancy and Breastfeeding is a manual offering both scientific and clinical evidence to empower health care providers and ensure they have the information necessary to confidently care for prospective and new parents.
From basic science to various anesthesia techniques to complications, the meticulously updated, fifth edition of Chestnut’s Obstetric Anesthesia: Principles and Practice, covers all you need to know about obstetric anesthesia. An editorial team of leading authorities presents the latest on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy. New chapters and rewritten versions of key chapters cover topics such as psychiatric disorders in the pregnant patient, neurologic disorders, and critical care of obstetric patients. It is an invaluable, comprehensive reference textbook for specialists in obstetric anesthesiology and obstetricians, as well as anesthesiology and obstetric residents. This book also serves as a clear, user-friendly guide for both anesthesiologists and obstetricians who are in clinical practice. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get all the accuracy, expertise, and dependability you could ask for from the most important names in the fields of obstetric anesthesia and maternal-fetal medicine. Master the current best practices you need to know for treating the fetus and the mother as separate patients—each with distinct needs. Search and retain difficult concepts easily with the help of key point summaries in each chapter. Stay current on the latest advancements and developments with sweeping updates and new chapters on topics such as patient safety and team approach, transthoracic echocardiography and noninvasive measurement of cardiac output in obstetric patients, psychiatric disorders during pregnancy, neurologic injuries, and more. Prevent and plan for potential complications associated with the advancing age of pregnant women. An extensive, state-of-the art discussion of "critical care of obstetric patients" equips you to address any special considerations for this increasing segment. Know exactly how to proceed. An abundance of tables and boxes illustrate the step-by-step management of a full range of clinical scenarios. Choose the best drugs available while adhering to the most recent guidelines for obstetric anesthesia.
Paleonutrition is the analysis of prehistoric human diets and the interpretation of dietary intake in relation to health and nutrition. As a field of study, it addresses prehistoric diets in order to determine the biological and cultural implications for individuals as well as for entire populations, placing archaeological interpretations into an anthropological context. Throughout history, and long before written records, human culture has been constantly in flux. The study of paleonutrition provides valuable insights into shifts and changes in human history, whatever their causes. This is the most comprehensive and up-to-date book on the topic. Intended for students and professionals, it describes the nature of paleonutrition studies, reviews the history of paleonutrition research, discusses methodological issues in the reconstruction of prehistoric diets, presents theoretical frameworks frequently used in paleonutrition research, and showcases examples in which paleonutritional analyses have been successfully conducted on prehistoric individuals, groups, and populations. It offers an integrative approach to understanding state-of-the-art anthropological dietary, health, and nutritional assessments. The most recent and innovative methods used to reconstruct prehistoric diets are discussed, along with the major ways in which paleonutrition data are recovered, analyzed, and interpreted. Paleonutrition includes five contemporary case studies that provide useful models of how to conduct paleonutrition research. Topics range from ancient diets in medieval Nubia to children’s health in the prehistoric American Southwest to honey use by an ethnographic group of East African foragers. As well as providing interesting examples of applying paleonutrition techniques, these case studies illustrate the mutually beneficial linkages between ethnography and archaeology.
Be prepared to diagnose and manage any condition you encounter in your practice! This bestselling reference gives you direct access to a complete range of full-color clinical images and patient radiographs that illustrate the differentiating characteristics of lesions in the oral and maxillofacial region. Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate osteonecrosis, the oral complications associated with methamphetamine abuse, solitary fibrous tumors, gene mutation, and plasminogen deficiency. - Over 1,300 clinical photos and radiographs, most in full color, facilitate identification and classification of lesions. - Current concepts of pathogenesis and disease management help you understand the diseases that affect the oral and maxillofacial structures, formulate an accurate diagnosis, and institute proper treatment. - Each chapter is logically organized by body system or disease group, enabling you to easily identify a specific condition. - A comprehensive appendix of differential diagnosis among oral and maxillofacial disease processes helps you rule out invalid diagnoses. - The bibliography divided by topic presented at the end of each chapter enables you to pursue supplemental literature. - Highly accomplished authors and contributors with a broad range of clinical and classroom teaching experience provide well-balanced coverage of the entire subject. - Chapter outlines at the beginning of each chapter allow immediate access to specific topics. - NEW cutting-edge content includes pathologies and conditions such as localized juvenile spongiotic gingival hyperplasia, oral lesions associated with cosmetic fillers, oropharyngeal carcinomas related to human papillomavirus (HPV), IgG4-related disease and mammary analogue secretory carcinomas, Globodontia, Lobodontia, Leishmaniasis, and Xanthelasma. - Over 130 NEW full-color photos and over 40 NEW radiographs bring common and uncommon disease states more clearly to life.
See how to identify and effectively manage oral diseases! Oral and Maxillofacial Pathology, 4th Edition provides state-of-the-art information on the wide variety of diseases that may affect the oral and maxillofacial region. Over 1,400 radiographs and full-color clinical photos - that's more than any other reference - bring pathologies and conditions to life. New to this edition is coverage of the latest advances in diagnosis and disease management, plus topics such as hereditary dental anomalies and oral lesions associated with cosmetic fillers. Written by well-known oral pathology educators Brad Neville, Douglas Damm, Carl Allen, and Angela Chi, this market leader is your go-to reference for the care of patients with oral disease! Comprehensive contemporary overview of oral and maxillofacial pathology includes a brief description of each individual lesion or pathologic condition and the kind of pathologic process that it represents, followed by a discussion of its clinical and/or radiographic presentation, histopathologic features, and its treatment and prognosis. Over 1,400 radiographs and full-color clinical photos facilitate the identification and classification of lesions and disease states. Up-to-date concepts of pathogenesis and disease management help you understand the diseases that affect oral and maxillofacial structures, formulate an accurate diagnosis, and institute proper treatment. Logical organization by body system or disease process makes it easy to look up specific conditions. Comprehensive appendix on differential diagnosis organizes disease entities according to their most prominent or identifiable clinical features, helping you find and formulate differential diagnoses. Information on forensic dentistry, methamphetamine, and gene mutations addresses some of today's leading topics in oral pathology research. Differential diagnosis case studies on the Evolve companion website include correct answers and rationales, offering more opportunities to improve your identification skills and diagnostic competency. NEW cutting-edge content includes pathologies and conditions such as localized juvenile spongiotic gingival hyperplasia, oral lesions associated with cosmetic fillers, oropharyngeal carcinomas related to human papillomavirus (HPV), IgG4-related disease and mammary analogue secretory carcinomas, Globodontia, Lobodontia, Leishmaniasis, and Xanthelasma. Over 130 NEW full-color photos and over 40 NEW radiographs bring common and uncommon disease states more clearly to life.
A history of the area that would become Walnut Station, then Walnut Grove from the earliest days to the present. It covers almost every aspect of community life in this small town in Minnesota.
In this comprehensive book, a naturopath explains why allergies occur and what works—and doesn't—to alleviate them. Millions of Americans suffer with allergies, yet medicine has yet to determine exactly what causes a person to be allergic. In this comprehensive book, naturopath Chris D. Meletis examines a wide-range of allergies, including those to foodstuffs, dust and other airborne allergens, and materials like latex and chemicals. He explores theories of why allergies occur and are rising, including the "hygiene hypothesis," which argues that overbathing and overuse of antibiotics and antibacterial agents means our immune systems never build up the necessary resistance to these substances when we are young.
Identify and effectively manage oral diseases with Oral and Maxillofacial Pathology! Comprehensive, stateof-the-art coverage includes a description of each individual lesion or pathologic condition, including a discussion of its clinical and/or radiographic presentation, histopathologic features, and its treatment and prognosis.• Over 1,400 radiographs and full-color clinical photos — that's more than any other reference — facilitate the identification and classification of lesions and disease states• Logical organization by body system or disease process makes it easy to look up specific conditions.• NEW cutting-edge content includes conditions and tumors such as localized juvenile spongiotic gingival hyperplasia, oral lesions associated with cosmetic fillers, HPV-related oropharyngeal carcinoma, IgG4-related disease, and mammary analogue secretory carcinoma• Coverage of oral pathology research topics includes current information on forensic dentistry, methamphetamine, and gene mutations• A comprehensive appendix organizes diseases according to their clinical features, helping you find and formulate differential diagnoses
The major cause of death in the Western world is some form of vascular disease; and principal among these forms is atherosclerotic heart disease (ASHD). Although much is known about the etiology and treatment of ASHD, there is, as yet, no specific means of prognosis of an impending coronary episode. There are, however, several indications of susceptibility to coronary disease, generally known as risk factors, the foremost of which is hyperlipidemia. Hyperlipidemia is more commonly designated as hypercholesteremia or triglyceridemia, depending upon which moiety is elevated, but since lipids are transported in the blood as members of a lipoprotein complex, the most descriptive general term would be hyperlipoproteinemia. This volume represents an effort to elucidate the origins and metabolic behavior of lipoproteins and their components, to describe aspects of the morphology, biochemistry and experimental induction of ASHD, and to describe modalities of treatment. The contributions to this book include descriptions of cholesterol synthesis and metabolism, as well as the metabolism of bile acids, the principal products of cholesterol metabolism. There are also chapters on the mechanisms of hyperlipidemia and on lipoprotein metabolism. The induction of experimental atherosclerosis and the aortic structural changes caused by this disease are discussed.
Since its inception, paleoanthropology has been closely wedded to the idea that big-game hunting by our hominin ancestors arose, first and foremost, as a means for acquiring energy and vital nutrients. This assumption has rarely been questioned, and seems intuitively obvious—meat is a nutrient-rich food with the ideal array of amino acids, and big animals provide meat in large, convenient packages. Through new research, the author of this volume provides a strong argument that the primary goals of big-game hunting were actually social and political—increasing hunter’s prestige and standing—and that the nutritional component was just an added bonus. Through a comprehensive, interdisciplinary research approach, the author examines the historical and current perceptions of protein as an important nutrient source, the biological impact of a high-protein diet and the evidence of this in the archaeological record, and provides a compelling reexamination of this long-held conclusion. This volume will be of interest to researchers in Archaeology, Evolutionary Biology, and Paleoanthropology, particularly those studying diet and nutrition.
Companion to Dental Anthropology presents a collection of original readings addressing all aspects and sub-disciplines of the field of dental anthropology—from its origins and evolution through to the latest scientific research. Represents the most comprehensive coverage of all sub-disciplines of dental anthropology available today Features individual chapters written by experts in their specific area of dental research Includes authors who also present results from their research through case studies or voiced opinions about their work Offers extensive coverage of topics relating to dental evolution, morphometric variation, and pathology
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