When originally published, A New History of Kentucky provided a comprehensive study of the Commonwealth, bringing it to life by revealing the many faces, deep traditions, and historical milestones of the state. With new discoveries and findings, the narrative continues to evolve, and so does the telling of Kentucky's rich history. In this second edition, authors James C. Klotter and Craig Thompson Friend provide significantly revised content with updated material on gender politics, African American history, and cultural history. This wide-ranging volume includes a full overview of the state and its economic, educational, environmental, racial, and religious histories. At its essence, Kentucky's story is about its people -- not just the notable and prominent figures but also lesser-known and sometimes overlooked personalities. The human spirit unfolds through the lives of individuals such as Shawnee peace chief Nonhelema Hokolesqua and suffrage leader Madge Breckinridge, early land promoter John Filson, author Wendell Berry, and Iwo Jima flag--raiser Private Franklin Sousley. They lived on a landscape defined by its topography as much as its political boundaries, from Appalachia in the east to the Jackson Purchase in the west, and from the Walker Line that forms the Commonwealth's southern boundary to the Ohio River that shapes its northern boundary. Along the journey are traces of Kentucky's past -- its literary and musical traditions, its state-level and national political leadership, and its basketball and bourbon. Yet this volume also faces forthrightly the Commonwealth's blemishes -- the displacement of Native Americans, African American enslavement, the legacy of violence, and failures to address poverty and poor health. A New History of Kentucky ranges throughout all parts of the Commonwealth to explore its special meaning to those who have called it home. It is a broadly interpretive, all-encompassing narrative that tells Kentucky's complex, extensive, and ever-changing story.
This is the Student Study Guide/Solutions Manual to accompany Organic Chemistry, 12th Edition. The 12th edition of Organic Chemistry continues Solomons, Fryhle & Snyder's tradition of excellence in teaching and preparing students for success in the organic classroom and beyond. A central theme of the authors' approach to organic chemistry is to emphasize the relationship between structure and reactivity. To accomplish this, the content is organized in a way that combines the most useful features of a functional group approach with one largely based on reaction mechanisms. The authors' philosophy is to emphasize mechanisms and their common aspects as often as possible, and at the same time, use the unifying features of functional groups as the basis for most chapters. The structural aspects of the authors' approach show students what organic chemistry is. Mechanistic aspects of their approach show students how it works. And wherever an opportunity arises, the authors' show students what it does in living systems and the physical world around us.
The enemy must not get the Messines Ridge at any price So read the orders to German troops defending the vital high ground south of Ypres. On 7 June 1917, the British Second Army launched its attack with an opening like no other. In the largest secret operation of the First World War, British and Commonwealth mining companies placed over a million pounds of explosive beneath the German front-line positions in 19 giant mines which erupted like a volcano. This was just the beginning. By the end of that brilliant summers day, one of the strongest positions on the Western Front had fallen in the greatest British victory in three long years of war. For the Anzacs, who comprised one third of the triumphant Second Army, it was their most significant achievement to that point; for the men of the New Zealand Division, it would be their finest hour.It is difficult to overstate the importance of Messines for the Australians, whose first two years of war had represented an almost unending catalogue of disaster. This was both the first real victory for the AIF and the first test in senior command for Major General John Monash, who commanded the newly formed 3rd Division. Messines was a baptism of fire for the 3rd Division which came into the line alongside the battle-scarred 4th Australian Division, badly mauled at Bullecourt just six weeks earlier. The fighting at Messines would descend into unimaginable savagery, a lethal and sometimes hand-to-hand affair of bayonets, clubs, bombs and incessant machine-gun fire, described by one Australian as 72 hours of Hell. After their string of bloody defeats over 1915 and 1916, Messines would prove the ultimate test for the Australians
Animal Welfare in a Pandemic explores the impact of COVID-19 on a wide array of animals, from those in the wild to companion and captive animals. During the height of the pandemic, a range of animals were infected, and many died, but this was hard to predict, even using up-to-date bioinformatics. Lockdowns around the world had, and continue to have, a major effect on animals’ welfare, influencing pet ownership and care, as well as impacting on the work of conservation institutes due to the lack of visitors and funding and lack of tourist presence in the wild which impacted on anti-poaching efforts. Some of the vast amount of personal protection equipment (PPE) that was distributed was discarded, creating both dangers and occasional opportunities for wild animals. With the rollout of human vaccines, some countries started developing animal vaccines, only some of which were deployed. In summary, the pandemic had a wide-ranging influence on animal welfare around the world. This is reviewed to highlight what can be learned to protect and enhance animal welfare in future epidemics/pandemics, and contribute to a genuinely One Health approach where the health and welfare of both humans and animals are considered holistically. This book is authored by members of the University of the West of England, Bristol, who span a range of expertise in Biological Sciences, Social Sciences, Animal Welfare, and Ethics.
Drawing on the authors’ experience in developing and implementing global mental health programs in crisis and development settings, A Guide to Global Mental Health Practice: Seeing the Unseen is designed for mental health, public health, and primary care professionals new to this emerging area. The guide is organized topically and divided into four sections that move from organizing and delivering global mental health services to clinical practice, and from various settings and populations likely to be encountered to special issues unique to global work. Case studies based around a central scene are threaded throughout the book to convey what global mental health work actually involves. Mental health professionals of all backgrounds, including social workers, nurses, nurse practitioners, psychologists, and psychiatrists, as well as public health professionals and community level medical professionals and mental health advocates will benefit from this engaging primer. It is the book for anyone committed to addressing mental health issues in a low resource or crisis-hit setting, whether international or domestic.
The dead and wounded of the 47th lay everywhere underfoot". With these words Charles Bean, Australia's Official War Historian, described the battlefield of Dernancourt on the morning of the 5th of April, 1918, strewn with the bodies of the Australian dead. It was the final tragic chapter in the story of the 47th Australian Infantry Battalion in the First World War. One of the shortest lived and most battle hardened of the 1st Australian Imperial Force's battalions, the 47th was formed in Egypt in 1916 and disbanded two years later having suffered one of the highest casualty rates of any Australian unit. Their story is remarkable for many reasons. Dogged by command and discipline troubles and bled white by the desperate attrition battles of 1916 and 1917, they fought on against a determined and skilful enemy in battles where the fortunes of war seemed stacked against them at every turn. Not only did they have the misfortune to be called into some of the A.I.F.'s most costly campaigns, chance often found them in the worst places within those battles. Though their story is one of almost unrelieved tragedy, it is also story of remarkable courage, endurance and heroism. It is the story of the 1st A.I.F. itself - punished, beaten, sometimes reviled for their indiscipline, they fought on - fewer, leaner and harder - until final victory was won. And at its end, in an extraordinary gesture of mateship, the remnants of the 47th Battalion reunited. Having been scattered to other units after their disbandment, the survivors gathered in Belgium for one last photo together. Only 73 remained.
This book provides a comprehensive overview of the nitrilimine 1,3-dipole, from its initial discovery in 1959 to the most recent publications. Covering topics such as the core properties of the dipole and the various methods of synthesis available, it particularly highlights the diverse reactivity profile of the nitrilimine and its numerous applications in bioorthogonal and materials chemistry. The book is of interest to academic and industrial researchers working in this area and to those new to the field.
Scotland was of grave strategic importance during the war because of its geographical position and its capital was the location of a significant number of important military and civil organizations. Edinburgh Castle became the HQ of the Scottish Home Forces whilst the Forth was a vitally important port and was heavily protected even before the start of the war. Its importance was marked by its attracting the first air raid of the war on mainland Britain when a force of German bombers was sent to attack naval shipping in the Forth on 16th October 1939. The raid was intercepted by the RAF which shot down at least two bombers and the entire action was witnessed by many civilians on the ground. The raid also caused the first civilian casualties when two women were injured in Edinburgh and two men machine-gunned in Portobello. Thousands lined the streets days later for the funeral of two of the Luftwaffe airmen.No member of the population of Edinburgh escaped the war, whether it was the huge numbers of men and women from the area who came forward for service in the military or in roles such as the Home Guard, ARP services, nursing, working in vital war industries, struggling to maintain a household under strict rationing and the stresses of wartime life, or children evacuated from the city to the rural areas of Scotland to escape the expected bombing campaign (even though the Archbishop of Edinburgh called for their return if there was insufficient provision of religious instruction in reception areas).Edinburgh was also home to a sizable Italian community which was badly affected by internment and the subsequent tight restrictions on movement and civil rights. The Italian community was also subjected to violent attacks when rioting mobs attacked Italian owned business throughout the city (although one family business was spared because one of the sons was known as a fanatical supporter of Hibs).Edinburgh at War 1939-1945 poignantly commemorates the efforts and achievements of Edinburgh: workers, fighters, families divided, all surviving astounding tests.
The Boy Scouts Association was just seven years old when war broke out in 1914. With its members brought up with a strong ethos of duty and loyalty, it was no surprise that many wanted to play the best role possible in the nation’s war effort. Many members were amongst those who rallied to the colors and enlisted in the heady days of the first weeks and months of the war. Some already belonged to either the Reserves or the Territorials and so found themselves immediately thrust into the front lines and casualty rates were high. Several of those who fought were decorated for their service, with a number even wining the Victoria Cross. On the Home Front, Boy Scouts served as messengers, printers, dispatch riders etc. in the War Office and other government offices, both locally and nationally. Scouts helped gather in the harvest, hunted for spies, aided the civil and military authorities, maintained watch during air raids, helped various wartime charities and sold old bottles to raise funds for recreational huts and ambulances for the front. Others found themselves mounting guard on the coasts and on vulnerable points such as the railway network, or aiding recruitment efforts across the country. The Boy Scout became a trusted and common sight on the streets of the country and the contribution they made was great indeed.
This laboratory manual is intended for a two-semester general chemistry course. The procedures are written with the goal of simplifying a complicated and often challenging subject for students by applying concepts to everyday life. This lab manual covers topics such as composition of compounds, reactivity, stoichiometry, limiting reactants, gas laws, calorimetry, periodic trends, molecular structure, spectroscopy, kinetics, equilibria, thermodynamics, electrochemistry, intermolecular forces, solutions, and coordination complexes. By the end of this course, you should have a solid understanding of the basic concepts of chemistry, which will give you confidence as you embark on your career in science.
“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.
A close-up look at the battle of Midway Island analyzes this crucial naval victory, which marked the turning point for the American fleet in the Pacific theater of World War II.
This new addition to the Urban Trails series of popular, close-to-home trails is designed for people of all fitness levels, from walkers to runners to cyclists, who want to get outside for fresh air and some exercise without a long drive or the need to do any planning. Urban Trails: Vancouvercovers all of Clark County (population approximately 500,000) from the Columbia River to the trails in the Yacolt Burn State Forest, as well as the Longview–Kelso and Kalama areas in neighboring Cowlitz County. Beyond the trails in Vancouver itself, it features hikes in Battle Ground, Ridgefield, La Center, Camas, and Washougal. Highlights include Lewis and Clark Expedition sites, American Indian sites, Fort Vancouver, and the city’s historic downtown.
Bacteria and Intracellularity clearly demonstrates that cellular microbiology as a field has reached maturity, extending beyond the strictly cellular level to infections of various organs and tissues. Decades of intense investigation into host-bacterial pathogen interactions have highlighted common concepts in intracellularity but also very diverse mechanisms underlying the various infections produced by bacteria. This book offers a wide-ranging look at the latest studies, including: foodborne pathogens, including how, when, and where bacteria interact with the gut and its microbiota infections of the urogenital tract, endothelial barriers, and the nervous system major advances in work with Mycobacterium tuberculosis and M. leprae subcellular microbiology, including metabolism of infected cells, nuclear biology, and microRNAs endosymbionts, in particular the latest work with Wolbachia and its effect on insect transmission of viral pathogens research into cell autonomous defense pathways that has led to major insights into immunology and innate immunity the latest developments in technology, for the next steps in the study of intracellularity All facets of cellular physiology, within the entire scope of cells and host tissues, can be targeted by pathogens. This book offers to researchers, students, and laboratorians a valuable overview of the state of current research into the cellular microbiology of host-pathogen interactions.
On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!
Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. It is an approach that reflects the challenge of teaching a subject that is in many ways unrecognizable from the molecular biology of the 20th century - a discipline in which our understanding has advanced immeasurably, but about which many intriguing questions remain to be answered. It is written with severalguiding themes in mind: - A focus on key principles provides a robust conceptual framework on which students can build a solid understanding of the discipline; - An emphasis on thecommonalities that exist between the three kingdoms of life, and the discussion of differences between the three kingdoms where such differences offer instructive insights into molecular processes and components, gives students an accurate depiction of our current understanding of the conserved nature of molecular biology, and the differences that underpin biological diversity; - An integrated approach demonstrates how certain molecular phenomena have diverse impacts on genomefunction by presenting them as themes that recur throughout the book, rather than as artificially separated topics At heart, molecular biology is an experimental science, and a centralelement to the understanding of molecular biology is an appreciation of the approaches taken to yield the information from which concepts and principles are deduced. Yet there is also the challenge of introducing the experimental evidence in a way that students can readily comprehend. Molecular Biology responds to this challenge with Experimental Approach panels, which branch off from the text in a clearly-signposted way. These panels describe pieces ofresearch that have been undertaken, and which have been particularly valuable in elucidating difference aspects of molecular biology. Each panel is carefully cross-referenced to the discussion of key molecular biologytools and techniques, which are presented in a dedicated chapter at the end of the book. Beyond this, Molecular Biology further enriches the learning experience with full-colour, custom-drawn artwork; end-of-chapter questions and summaries; relevant suggested further readings grouped by topic; and an extensive glossary of key terms. Among the students being taught today are the molecular biologists of tomorrow; these individuals will be ina position to ask fascinating questions about fields whose complexity and sophistication become more apparent with each year that passes. Molecular Biology: Principles of Genome Function is the perfectintroduction to this challenging, dynamic, but ultimately fascinating discipline.
Tackling environmental issues such as global warming, ozone depletion, acid rain, water pollution, and soil contamination requires an understanding of the underlying science and chemistry of these processes in real-world systems and situations. Chemistry for Environmental and Earth Sciences provides a student-friendly introduction to the bas
William Green, president of the American Federation of Labor from 1924 to 1952, was a controversial figure whom historians invariably depict as bumbling, incompetent, vain, and ignorant; the cheerful servant of selfish and reactionary craft uinionists, and the person most directly responsible for the split in organized labor in 1935. This biography provides a social and political context for Green's actions in an attempt to vindicate one of the last heirs of a religiously inspired trade unionism that sought cooperation between labor and capital on the basis of biblical precepts.
The gold standard resource in the field, Rehabilitation of the Spine: A Patient-Centered Approach provides a practical overview of all aspects of spinal rehabilitation. The 3rd Edition has been completely revised, with new information to bring you up to date. Comprehensive and easy to read, this reference is invaluable for chiropractors and physical therapists, as well as spine surgeons, physician assistants, and nurse practitioners involved in the care of patients with spine problems.
The NIV Application Commentary helps you communicate and apply biblical text effectively in today's context. To bring the ancient messages of the Bible into today's world, each passage is treated in three sections: Original Meaning. Concise exegesis to help readers understand the original meaning of the biblical text in its historical, literary, and cultural context. Bridging Contexts. A bridge between the world of the Bible and the world of today, built by discerning what is timeless in the timely pages of the Bible. Contemporary Significance. This section identifies comparable situations to those faced in the Bible and explores relevant application of the biblical messages. The author alerts the readers of problems they may encounter when seeking to apply the passage and helps them think through the issues involved. This unique, award-winning commentary is the ideal resource for today's preachers, teachers, and serious students of the Bible, giving them the tools, ideas, and insights they need to communicate God's Word with the same powerful impact it had when it was first written.
The enemy must not get the Messines Ridge at any price… So read the orders to German troops defending the vital high ground south of Ypres. On 7 June 1917, the British Second Army launched its attack with an opening like no other. In the largest secret operation of the First World War, British and Commonwealth mining companies placed over a million pounds of explosive beneath the German front-line positions in 19 giant mines which erupted like a volcano. This was just the beginning. By the end of that brilliant summer’s day, one of the strongest positions on the Western Front had fallen in the greatest British victory in three long years of war. For the ANZACs, who comprised one third of the triumphant Second Army, it was their most significant achievement to that point; for the men of the New Zealand Division, it would be their finest hour. It is difficult to overstate the importance of Messines for the Australians, whose first two years of war had represented an almost unending catalogue of disaster. This was both the first real victory for the AIF and the first test in senior command for Major General John Monash, who commanded the newly formed 3rd Division. Messines was a baptism of fire for the 3rd Division which came into the line alongside the battle-scarred 4th Australian Division, badly mauled at Bullecourt just six weeks earlier. The fighting at Messines would descend into unimaginable savagery, a lethal and sometimes hand-to-hand affair of bayonets, clubs, bombs and incessant machine-gun fire, described by one Australian as ‘72 hours of Hell’. After their string of bloody defeats over 1915 and 1916, Messines would prove the ultimate test for the Australians.
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