The challenges facing humanity in the 21st century include climate change, population growth, overconsumption of resources, overproduction of waste and increasing energy demands. For construction practitioners, responding to these challenges means creating a built environment that provides accommodation and infrastructure with better whole-life performance using lower volumes of primary materials, less non-renewable energy, wasting less and causing fewer disturbances to the natural environment. Concrete is ubiquitous in the built environment. It is therefore essential that it is used in the most sustainable way so practitioners must become aware of the range of sustainable concrete solutions available for construction. While sustainable development has been embedded into engineering curricula, it can be difficult for students and academics to be fully aware of the innovations in sustainable construction that are developed by the industry. Sustainable Concrete Solutions serves as an introduction to and an overview of the latest developments in sustainable concrete construction. It provides useful guidance, with further references, to students, researchers, academics and practitioners of all construction disciplines who are faced with the challenge of designing, specifying and constructing with concrete.
This textbook explains the fundamental aspects of nanotechnology and fills the gap between bio-inspired nanotechnological systems and functionality of living organisms, introducing new insights to their physicochemical, biophysical and thermodynamic behaviour. Addressed to all those involved in recent advances in pharmaceutics, this book is divided in three major parts: Part A refers to the physicochemical and thermodynamics aspects of nanosystems, wherein their biophysical behaviour is correlated with that of the cells of living organisms; Part B refers to the application of nanotechnology in imaging, diagnostics and therapeutics; Part C is focused on issues regarding safety and nanotoxicity of nanosystems, and the regulatory framework that surrounds these. The text promotes the concept that biophysics, thermodynamics and nanotechnology are considered to be emerging tools that, when approached within regulatory boundaries, provide new and integrated knowledge for the production of new medicines. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.
Nanotechnology in Therapeutics Comprehensive reference delivering a framework to develop and assess nanosystems that provide unique advantages in biomedical applications Nanotechnology in Therapeutics explores the idea that by studying in depth the behavior of living organisms, especially the functionality of their cell membranes, we can develop and evaluate innovative bio-inspired nanosystems that are able to deliver small molecules, biomolecules like proteins, peptides, and other genetic material in terms of the production of new therapies and vaccines. The main concept promoted in this book is an integrated approach for producing new medicines following the nanotoxicity, biotoxicity, regulatory, and ethical guidelines, which are also covered in the book. The book is divided into three parts. Part A provides an introduction and a historical overview of nanotechnology. Part B delves deeper into issues relating to lipid and polymeric nanostructures in medicine. Part C presents the regulatory landscape around nanotechnology and nanomedicine, while highlighting the need to keep an eye on emerging technologies such as artificial intelligence and machine learning. Overall, this book opens up biomedical applications for previously challenging drugs and drug targets. Written by a highly qualified professor with significant pertinent research experience, Nanotechnology in Therapeutics includes discussion on: Eukaryotic cell membranes, their structural properties, and the thermodynamic payload of their lipid bilayers The DLVO (Derjaguin, Landau, Verwey and Overbeek) theory as a scientific tool for studying the stability and the behavior of nanoparticles Liposomes, lipid nanoparticles, and solid lipid nanoparticles, as well as polymeric nanoparticles, like micelles, polymersomes, and dendrimers Issues in the approval process of nanomedicines by the regulatory agencies, such as complexity, chaos, and nonlinear dynamics With comprehensive coverage of novel concepts that have the potential to transform how new medicines are designed and developed, Nanotechnology in Therapeutics is an essential resource on the subject for chemists in industry, as well as biomedical and pharmaceutical engineers.
The challenges facing humanity in the 21st century include climate change, population growth, overconsumption of resources, overproduction of waste and increasing energy demands. For construction practitioners, responding to these challenges means creating a built environment that provides accommodation and infrastructure with better whole-life performance using lower volumes of primary materials, less non-renewable energy, wasting less and causing fewer disturbances to the natural environment. Concrete is ubiquitous in the built environment. It is therefore essential that it is used in the most sustainable way so practitioners must become aware of the range of sustainable concrete solutions available for construction. While sustainable development has been embedded into engineering curricula, it can be difficult for students and academics to be fully aware of the innovations in sustainable construction that are developed by the industry. Sustainable Concrete Solutions serves as an introduction to and an overview of the latest developments in sustainable concrete construction. It provides useful guidance, with further references, to students, researchers, academics and practitioners of all construction disciplines who are faced with the challenge of designing, specifying and constructing with concrete.
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