Committee to Study Priorities for Vaccine Development's Books

Vaccines for the 21st Century

A Tool for Decisionmaking

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development

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Vaccines for the 21st Century

A Tool for Decisionmaking

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development

Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

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473

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National Academies Press

Published Date

ISBN 10

0309056462

ISBN 13

9780309056465

Vaccines for the 21st Century

A Tool for Decisionmaking

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development

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Vaccines for the 21st Century

A Tool for Decisionmaking

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Study Priorities for Vaccine Development

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473

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National Academies Press

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ISBN 10

0309056462

ISBN 13

9780309056465

Ranking Vaccines

A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System

By: Committee on Identifying and Prioritizing New Preventive Vaccines for Development, Phase II,Board on Population Health and Public Health Practice,Board on Global Health,Institute of Medicine

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Ranking Vaccines

A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System

By: Committee on Identifying and Prioritizing New Preventive Vaccines for Development, Phase II,Board on Population Health and Public Health Practice,Board on Global Health,Institute of Medicine

SMART Vaccines--Strategic Multi-Attribute Ranking Tool for Vaccines--is a prioritization software tool developed by the Institute of Medicine that utilizes decision science and modeling to help inform choices among candidates for new vaccine development. A blueprint for this computer-based guide was presented in the 2012 report Ranking Vaccines: A Prioritization Framework: Phase I. Ranking Vaccines: A Prioritization Software Tool,Phase II extends the proof-of-concept presented in the Phase I report, which was based on multi-attribute utility theory. This report refines a beta version of the model developed in the Phase I report and presents its next iteration, SMART Vaccines 1.0. Ranking Vaccines: Phase II discusses the methods underlying the development, validation, and evaluation of SMART Vaccines 1.0. It also discusses how SMART Vaccines should--and, just as importantly, should not--be used. The report also offers ideas for future enhancements for SMART Vaccines as well as for ideas for expanded uses and considerations and possibilities for the future.

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156

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National Academies Press

Published Date

ISBN 10

0309266394

ISBN 13

9780309266390

The Children's Vaccine Initiative

Achieving the Vision

By: Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies

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The Children's Vaccine Initiative

Achieving the Vision

By: Institute of Medicine,Committee on the Children's Vaccine Initiative: Planning Alternative Strategies

The Children's Vaccine Initiative is an international endeavor to ensure that children throughout the world are immunized. This book notes that one of the best opportunities to address the growing problem of immunization in the United States and to improve the health of children in developing countries lies in marshaling the vaccine development and production efforts in the United States and abroad. The book contains information on the nature and status of vaccine development and production efforts in the United States and abroad, and it recommends ways to enhance participation in the International Children's Vaccine Initiative.

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238

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National Academies Press

Published Date

ISBN 10

0309049407

ISBN 13

9780309049405

Opportunities in Biotechnology for Future Army Applications

By: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications

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Opportunities in Biotechnology for Future Army Applications

By: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications

This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.

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118

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National Academies Press

Published Date

ISBN 10

0309170737

ISBN 13

9780309170734

The AIDS Research Program of the National Institutes of Health

By: Institute of Medicine,Committee to Study the AIDS Research Program of the National Institutes of Health

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The AIDS Research Program of the National Institutes of Health

By: Institute of Medicine,Committee to Study the AIDS Research Program of the National Institutes of Health

This book, written at the request of the National Institutes of Health (NIH) to assist its AIDS program office in planning future directions, contains a series of recommendations for ensuring that AIDS research is a well-organized, well-planned, and comprehensive long-range program leading to the control and eventual eradication of the disease. The recommendations are intended to strengthen the planning, evaluation, and coordination of AIDS research activities; ensure their quality and cost-effectiveness; stimulate further development of promising research areas; increase the level of support for AIDS research so that researchers can carry out a comprehensive program; and provide the personnel and facilities at NIH needed to conduct and manage an effective, efficient AIDS research program. The book also identifies barriers in the delivery and financing of health care that are outside NIH's responsibility, but that adversely affect its AIDS clinical research efforts, and urges federal action to eliminate them.

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Page Count

155

Publisher

National Academies Press

Published Date

ISBN 10

0309044367

ISBN 13

9780309044363

Ranking Vaccines

A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System

By: Institute of Medicine,Board on Global Health,Board on Population Health and Public Health Practice,Committee on Identifying and Prioritizing New Preventive Vaccines for Development, Phase II

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Ranking Vaccines

A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System

By: Institute of Medicine,Board on Global Health,Board on Population Health and Public Health Practice,Committee on Identifying and Prioritizing New Preventive Vaccines for Development, Phase II

SMART Vaccines-Strategic Multi-Attribute Ranking Tool for Vaccines-is a prioritization software tool developed by the Institute of Medicine that utilizes decision science and modeling to help inform choices among candidates for new vaccine development. A blueprint for this computer-based guide was presented in the 2012 report Ranking Vaccines: A Prioritization Framework: Phase I. Ranking Vaccines: A Prioritization Software Tool,Phase II extends the proof-of-concept presented in the Phase I report, which was based on multi-attribute utility theory. This report refines a beta version of the model developed in the Phase I report and presents its next iteration, SMART Vaccines 1.0. Ranking Vaccines: Phase II discusses the methods underlying the development, validation, and evaluation of SMART Vaccines 1.0. It also discusses how SMART Vaccines should-and, just as importantly, should not-be used. The report also offers ideas for future enhancements for SMART Vaccines as well as for ideas for expanded uses and considerations and possibilities for the future.

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156

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National Academies Press

Published Date

ISBN 10

0309266416

ISBN 13

9780309266413

Priorities for the National Vaccine Plan

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan

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Priorities for the National Vaccine Plan

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan

Vaccination is a fundamental component of preventive medicine and public health. The use of vaccines to prevent infectious diseases has resulted in dramatic decreases in disease, disability, and death in the United States and around the world. The current political, economic, and social environment presents both opportunities for and challenges to strengthening the U.S. system for developing, manufacturing, regulating, distributing, funding, and administering safe and effective vaccines for all people. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. The book makes recommendations about priority actions in the update to the National Vaccine Plan that are intended to achieve the objectives of disease prevention and enhancement of vaccine safety. It is centered on the plan's five goals in the areas of vaccine development, safety, communication, supply and use, and global health.

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Page Count

368

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National Academies Press

Published Date

ISBN 10

0309156203

ISBN 13

9780309156202

Priorities for the National Vaccine Plan

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan

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Priorities for the National Vaccine Plan

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Review of Priorities in the National Vaccine Plan

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Page Count

368

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National Academies Press

Published Date

ISBN 10

0309156203

ISBN 13

9780309156202

Initial Guidance for an Update of the National Vaccine Plan

A Letter Report to the National Vaccine Program Office

By: Committee on the Review of Priorities in the National Vaccine Plan,Board on Population Health and Public Health Practice,Institute of Medicine

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Initial Guidance for an Update of the National Vaccine Plan

A Letter Report to the National Vaccine Program Office

By: Committee on the Review of Priorities in the National Vaccine Plan,Board on Population Health and Public Health Practice,Institute of Medicine

This book is the Institute of Medicine's response to the first part of the statement of task asking for a review of the 1994 National Vaccine Plan. The Committee on the Review of Priorities in the National Vaccine Plan reviewed the goals, objectives, strategies, and anticipated outcomes presented in the plan; their findings are contained in this book. In the first section of the book, the committee examines what has changed in the broader social, policy, and economic context of vaccine development and immunization, and highlights several areas where noteworthy progress has been made, particularly by federal agencies. The committee acknowledges that progress in developing and delivering vaccines has benefited from essential contributions by other stakeholders, including researchers, manufacturers, state and local public health agencies, and health care providers. In the second section of the book, the committee uses what it learned from reviewing the 1994 plan and the process of preparing it to distill key elements. Based on these elements, the committee offers guidance to NVPO and its partners on developing the update to the national vaccine plan.

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National Academies Press

Published Date

ISBN 10

0309121981

ISBN 13

9780309121989

New Vaccine Development

Establishing Priorities: Volume II, Diseases of Importance in Developing Countries

By: Institute of Medicine,Board on Population Health and Public Health Practice,Division of Health Promotion and Disease Prevention,Division of International Health

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New Vaccine Development

Establishing Priorities: Volume II, Diseases of Importance in Developing Countries

By: Institute of Medicine,Board on Population Health and Public Health Practice,Division of Health Promotion and Disease Prevention,Division of International Health

Common diseases cost the developing world an enormous amount in terms of human life, health, and productivity, as well as lost economic potential. New and effective vaccines could not only improve the quality of life for millions of residents in developing countries, they could also contribute substantially to further economic development. Using data from the World Health Organization and other international agencies, this book analyzes disease burdens, pathogen descriptions, geographic distribution of diseases, probable vaccine target populations, alternative control measures and treatments, and future prospects for vaccine development. New Vaccine Development provides valuable insight into immunological and international health policy priorities.

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Page Count

452

Publisher

National Academies Press

Published Date

ISBN 10

0309036798

ISBN 13

9780309036795

Book's by Committee to Study Priorities for Vaccine Development

Vaccines for the 21st Century

Vaccines for the 21st Century

Vaccines for the 21st Century

Vaccines for the 21st Century

Ranking Vaccines

Ranking Vaccines

The Children's Vaccine Initiative

The Children's Vaccine Initiative

Opportunities in Biotechnology for Future Army Applications

Opportunities in Biotechnology for Future Army Applications

The AIDS Research Program of the National Institutes of Health

The AIDS Research Program of the National Institutes of Health

Ranking Vaccines

Ranking Vaccines

Priorities for the National Vaccine Plan

Priorities for the National Vaccine Plan

Priorities for the National Vaccine Plan

Priorities for the National Vaccine Plan

Initial Guidance for an Update of the National Vaccine Plan

Initial Guidance for an Update of the National Vaccine Plan

New Vaccine Development

New Vaccine Development

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