Committee to Review Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick's Books

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

A Letter Report

By: National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee to Review Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

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Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

A Letter Report

Fort Detrick's Area B has been used for disposal of chemical, biological, and radiological material, storage of explosives, and research activities. The groundwater of Area B was contaminated by perchloroethylene (PCE) and trichloroethylene (TCE), which leaked from storage drums buried in Area B. Members of the public who live near Fort Detrick in Frederick County, Maryland, are concerned that the contaminated groundwater might have affected their health. This report reviews two investigations of potential health hazards: a 2009 public health assessment conducted by the Agency for Toxic Substances and Disease Registry and a cancer investigation in Frederick County by the Maryland Department of Health and Mental Hygiene and the Frederick County Health Department.

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National Academies Press

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ISBN 10

0309254892

ISBN 13

9780309254892

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

A Letter Report

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Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

A Letter Report

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ISBN 10

0309254892

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9780309254892

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Volume 17

By: National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Committee on Acute Exposure Guideline Levels

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Acute Exposure Guideline Levels for Selected Airborne Chemicals

Volume 17

By: National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Committee on Acute Exposure Guideline Levels

Extremely hazardous substances can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where these substances are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 17 identifies, reviews, and interprets relevant toxicologic and other scientific data for selected AEGL documents for acrylonitrile, carbon tetrachloride, cyanogen, epichlorohydrin, ethylene chlorohydrin, toluene, trimethylacetyl chloride, hydrogen bromide, and boron tribromide in order to develop acute exposure guideline levels (AEGLs) for these high-priority, acutely toxic chemicals. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels - AEGL-1, AEGL-2, and AEGL-3 - are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

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405

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National Academies Press

Published Date

ISBN 10

0309304792

ISBN 13

9780309304795

Acute Exposure Guideline Levels for Selected Airborne Chemicals

By: Committee on Acute Exposure Guideline Levels,Committee on Toxicology,Board on Environmental Studies and Toxicology,Division on Earth and Life Studies,National Research Council

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Acute Exposure Guideline Levels for Selected Airborne Chemicals

By: Committee on Acute Exposure Guideline Levels,Committee on Toxicology,Board on Environmental Studies and Toxicology,Division on Earth and Life Studies,National Research Council

Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 15 identifies, reviews, and interprets relevant toxicologic and other scientific data for ethyl mercaptan, methyl mercaptan, phenyl mercaptan, tert-octyl mercaptan, lewisite, methyl isothiocyanate, and selected monoisocyanates in order to develop acute exposure guideline levels (AEGLs) for these high-priority, acutely toxic chemicals. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three level--AEGL-1, AEGL-2, and AEGL-3--are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

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229

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National Academies Press

Published Date

ISBN 10

0309291232

ISBN 13

9780309291231

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Volume 20

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Committee on Acute Exposure Guideline Levels

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Acute Exposure Guideline Levels for Selected Airborne Chemicals

Volume 20

Extremely hazardous substances can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where these substances are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 20 reviews and updates the technical support document on acute exposure guideline levels (AEGLs) for selected chloroformates. This update focuses on establishing AEGL-3 values for n-propyl chloroformate and isopropyl chloroformate, but will also consider whether any new data are available that would affect the proposed values for the other 10 chloroformates. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels - AEGL-1, AEGL-2, and AEGL-3 - are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.

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195

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National Academies Press

Published Date

ISBN 10

0309449154

ISBN 13

9780309449151

Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites

By: National Research Council,Division on Earth and Life Studies,Water Science and Technology Board,Committee on Future Options for Management in the Nation's Subsurface Remediation Effort

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Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites

By: National Research Council,Division on Earth and Life Studies,Water Science and Technology Board,Committee on Future Options for Management in the Nation's Subsurface Remediation Effort

Across the United States, thousands of hazardous waste sites are contaminated with chemicals that prevent the underlying groundwater from meeting drinking water standards. These include Superfund sites and other facilities that handle and dispose of hazardous waste, active and inactive dry cleaners, and leaking underground storage tanks; many are at federal facilities such as military installations. While many sites have been closed over the past 30 years through cleanup programs run by the U.S. Department of Defense, the U.S. EPA, and other state and federal agencies, the remaining caseload is much more difficult to address because the nature of the contamination and subsurface conditions make it difficult to achieve drinking water standards in the affected groundwater. Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites estimates that at least 126,000 sites across the U.S. still have contaminated groundwater, and their closure is expected to cost at least $110 billion to $127 billion. About 10 percent of these sites are considered "complex," meaning restoration is unlikely to be achieved in the next 50 to 100 years due to technological limitations. At sites where contaminant concentrations have plateaued at levels above cleanup goals despite active efforts, the report recommends evaluating whether the sites should transition to long-term management, where risks would be monitored and harmful exposures prevented, but at reduced costs.

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423

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National Academies Press

Published Date

ISBN 10

0309278740

ISBN 13

9780309278744

Veterans and Agent Orange

Update 2000

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third Biennial Update)

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Veterans and Agent Orange

Update 2000

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third Biennial Update)

Veterans and Agent Orange: Update 2000 examines the state of the scientific evidence regarding associations between diseases and exposure to dioxin and other chemical compounds in herbicides used in Vietnam. It is the fourth in a series of comprehensive reviews of epidemiologic and toxicologic studies of the agents used as defoliants during the Vietnam War. Over forty health outcomes in veterans and their children are addressed. Among the report's conclusions is that there is sufficient evidence of a link between exposure and the development of soft-tissue sarcoma, non-Hodgkin's lymphoma, Hodgkin's disease, and chloracne in veterans. Additionally, it found that scientific studies offer "limited or suggestive" evidence of an association with other diseases in veteransâ€"including Type 2 diabetes, respiratory cancers, prostate cancer, multiple myeloma and some forms of transient peripheral neuropathyâ€"as well as the congenital birth defect spina bifida in veterans' children.

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622

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National Academies Press

Published Date

ISBN 10

0309171016

ISBN 13

9780309171014

Cities and Their Vital Systems

Infrastructure Past, Present, and Future

By: Advisory Committee on Technology and Society

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Cities and Their Vital Systems

Infrastructure Past, Present, and Future

By: Advisory Committee on Technology and Society

Cities and Their Vital Systems asks basic questions about the longevity, utility, and nature of urban infrastructures; analyzes how they grow, interact, and change; and asks how, when, and at what cost they should be replaced. Among the topics discussed are problems arising from increasing air travel and airport congestion; the adequacy of water supplies and waste treatment; the impact of new technologies on construction; urban real estate values; and the field of "telematics," the combination of computers and telecommunications that makes money machines and national newspapers possible.

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1298

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National Academies Press

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ISBN 10

0309037867

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9780309037860

Book's by Committee to Review Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

Review of Studies of Possible Toxic Effects from Past Environmental Contamination at Fort Detrick

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites

Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites

Veterans and Agent Orange

Veterans and Agent Orange

Cities and Their Vital Systems

Cities and Their Vital Systems

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