Committee to Assess the Safety and Efficacy of the Anthrax Vaccine's Books

An Assessment of the CDC Anthrax Vaccine Safety and Efficacy Research Program

By: Committee to Review the CDC Anthrax Vaccine Safety and Efficacy Research Program,Medical Follow-Up Agency,Institute of Medicine

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An Assessment of the CDC Anthrax Vaccine Safety and Efficacy Research Program

By: Committee to Review the CDC Anthrax Vaccine Safety and Efficacy Research Program,Medical Follow-Up Agency,Institute of Medicine

In 1998, the Department of Defense (DoD) began a program of mandatory immunization against anthrax for all military personnel. As the program proceeded, however, some military personnel and their families raised concerns about the safety and efficacy of the anthrax vaccine. Acknowledging both the need to protect military personnel and the concerns about the anthrax vaccine, congress directed the Centers for Disease Control and Prevention (CDC) to carry out a research program on its safety and efficacy. To assist in the development of this program, CDC requested the Institute of Medicine (IOM) to convene a committee to review the completeness and appropriateness of the research program. In An Assessment of the CDC Anthrax Vaccine Safety and Efficacy Research Program, the committee makes an overall assessment of the CDD research plan and reviews the specific studies proposed by CDC in the three areas of efficacy, safety and acceptability. The committee also notes additional research needs that became evident following the bioterrorist events of 2001 and makes recommendations about the leadership of the research program.

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Page Count

179

Publisher

National Academies Press

Published Date

ISBN 10

0309168953

ISBN 13

9780309168953

The Anthrax Vaccine

Is It Safe? Does It Work?

By: Institute of Medicine,Medical Follow-up Agency,Committee to Assess the Safety and Efficacy of the Anthrax Vaccine

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The Anthrax Vaccine

Is It Safe? Does It Work?

By: Institute of Medicine,Medical Follow-up Agency,Committee to Assess the Safety and Efficacy of the Anthrax Vaccine

The vaccine used to protect humans against the anthrax disease, called Anthrax Vaccine Adsorbed (AVA), was licensed in 1970. It was initially used to protect people who might be exposed to anthrax where they worked, such as veterinarians and textile plant workers who process animal hair. When the U. S. military began to administer the vaccine, then extended a plan for the mandatory vaccination of all U. S. service members, some raised concerns about the safety and efficacy of AVA and the manufacture of the vaccine. In response to these and other concerns, Congress directed the Department of Defense to support an independent examination of AVA. The Anthrax Vaccine: Is It Safe? Does It Work? reports the study's conclusion that the vaccine is acceptably safe and effective in protecting humans against anthrax. The book also includes a description of advances needed in main areas: improving the way the vaccine is now used, expanding surveillance efforts to detect side effects from its use, and developing a better vaccine.

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