Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans's Books

Chronic Multisymptom Illness in Gulf War Veterans:

Case Definitions Reexamined

By: Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans,Board on the Health of Select Populations,Institute of Medicine

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Chronic Multisymptom Illness in Gulf War Veterans:

Case Definitions Reexamined

By: Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans,Board on the Health of Select Populations,Institute of Medicine

More than 2 decades have passed since the 1990-1991 conflict in the Persian Gulf. During the intervening years, many Gulf War veterans have experienced various unexplained symptoms that many associate with service in the gulf region, but no specific exposure has been definitively associated with symptoms. Numerous researchers have described the pattern of signs and symptoms found in deployed Gulf War veterans and noted that they report unexplained symptoms at higher rates than nondeployed veterans or veterans deployed elsewhere during the same period. Gulf War veterans have consistently shown a higher level of morbidity than the nondeployed, in some cases with severe and debilitating consequences. However, efforts to define a unique illness or syndrome in Gulf War veterans have failed, as have attempts to develop a uniformly accepted case definition. Chronic Multisymptom Illness in Gulf War Veterans is a comprehensive review of the available scientific and medical literature regarding symptoms for chronic multisymptom illness (CMI) among the 1991 Gulf War Veterans. This report evaluates and summarizes the literature in an effort to identify appropriate terminology to use in referring to CMI in Gulf War Veterans. While the report does not recommend one specific case definition over another, Chronic Multisymptom Illness in Gulf War Veterans does recommend the consideration of two case definitions on the basis of their concordance with the evidence and their ability to identify specific symptoms commonly reported by Gulf War veterans. This report recommends that the Department of Veterans Affairs use the term Gulf War illness rather than CMI. The report recommends that that the Department of Veterans Affairs, to the extent possible, systematically assess existing data to identify additional features of Gulf War illness, such as onset, duration, severity, frequency of symptoms, and exclusionary criteria to produce a more robust case definition.

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National Academies Press

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ISBN 10

0309387639

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9780309387637

Chronic Multisymptom Illness in Gulf War Veterans

Case Definitions Reexamined

By: Institute of Medicine,Board on the Health of Select Populations,Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans

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Chronic Multisymptom Illness in Gulf War Veterans

Case Definitions Reexamined

By: Institute of Medicine,Board on the Health of Select Populations,Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans

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131

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National Academies Press

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ISBN 10

0309298768

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9780309298766

Gulf War and Health

Volume 10: Update of Health Effects of Serving in the Gulf War, 2016

By: National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on the Health of Select Populations,Committee on Gulf War and Health, Volume 10: Update of Health Effects of Serving in the Gulf War

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Gulf War and Health

Volume 10: Update of Health Effects of Serving in the Gulf War, 2016

For the United States, the 1991 Persian Gulf War was a brief and successful military operation with few injuries and deaths. However, soon after returning from duty, a large number of veterans began reporting health problems they believed were associated with their service in the Gulf. At the request of Congress, the Institute of Medicine (IOM) has been conducting an ongoing review of the evidence to determine veterans' long-term health problems and potential causes. The fourth volume in the series, released in 2006, summarizes the long-term health problems seen in Gulf War veterans. In 2010, the IOM released an update that focuses on existing health problems and identifies possible new ones, considering evidence collected since the initial summary. Gulf War and Health: Volume 10 is an update of the scientific and medical literature on the health effects associated with deployment to the Gulf War that were identified in Volumes 4 and 8. This report reviews and evaluates the associations between illness and exposure to toxic agents, environmental or wartime hazards, or preventive measures and vaccines associated with Gulf War service, and provides recommendations for future research efforts on Gulf War veterans.

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293

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National Academies Press

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ISBN 10

0309380448

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9780309380447

The Air Force Health Study Assets Research Program

By: Institute of Medicine,Board on the Health of Select Populations,Committee on the Management of the Air Force Health Study Data and Specimens--Report to Congress

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The Air Force Health Study Assets Research Program

By: Institute of Medicine,Board on the Health of Select Populations,Committee on the Management of the Air Force Health Study Data and Specimens--Report to Congress

The Air Force Health Study (AFHS) is a longitudinal, prospective epidemiologic study of more than 2,700 men followed for approximately 20 years. This cohort participated in up to six intensive physical examinations with high rates of compliance. In addition to a complete record of clinical measurements and observations collected at these exams, serum and other biological samples were obtained and preserved. Extensive questionnaires addressing health, lifestyle, and socioeconomic status were administered during each exam, and other information was obtained about the participants' employment, families and offspring, and potential sources of environmental exposures. While the study was completed in 2006, the extensive health data linked to several types of longitudinally collected biologic specimens - some 91,000 serum, whole blood, urine, semen, and adipose tissue specimens - remain a resource for additional research. The AFHS assets are exceptional in the sheer multitude and range of types of information available for each participant. The longitudinal nature of the AFHS - with its extended follow-up, high rates of retention, and repeat biological samples - provides a valuable opportunity for research beyond the original aims of the study. Currently, the Institute of Medicine is the custodian of these assets. The Air Force Health Study Assets Research Program outlines the feasibility and advisability of maintaining the biospecimens based on interest generated from the general scientific community and results of pilot projects and other research projects using the AFHS assets. According to this report, sustaining access to the AFHS biospecimens and data benefits the veterans community and the public at large, who will gain from the information derived from studies of the assets. . This report discusses the scientific value of the AFHS data and biospecimens and the lessons learned in managing access to the assets.

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202

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National Academies Press

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ISBN 10

0309339170

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9780309339179

Gulf War and Health

Volume 4: Health Effects of Serving in the Gulf War

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Gulf War and Health: A Review of the Medical Literature Relative to the Gulf War Veterans' Health

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Gulf War and Health

Volume 4: Health Effects of Serving in the Gulf War

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Gulf War and Health: A Review of the Medical Literature Relative to the Gulf War Veterans' Health

In 1998, in response to the growing concerns that many returning Gulf War veterans began reporting numerous health problems that they believed to be associated with their service in the Persian Gulf, Congress passed two laws which directed the Secretary of Veterans Affairs to enter into a contract with the National Academy of Sciences. They were tasked to review and evaluate the scientific and medical literature regarding associations between illness and exposure to toxic agents, environmental or wartime hazards, and preventive medicines or vaccines associated with Gulf War service. In addition, the Institute of Medicine of the National Academy of Sciences provided conclusions to these studies that were considered when making decisions about compensation to veterans. Gulf War and Health Volume 4: Health Effects of Serving in the Gulf War summarizes in one place the current status of health effects in veterans deployed to the Persian Gulf irrespective of exposure information. This book reviews, evaluates, and summarizes both peer-reviewed scientific and medical literature addressing the health status of Gulf War veterans.

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292

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National Academies Press

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ISBN 10

0309164567

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9780309164566

Gulf War and Health

Volume 8: Update of Health Effects of Serving in the Gulf War

By: Institute of Medicine,Board on the Health of Select Populations,Committee on Gulf War and Health: Health Effects of Serving in the Gulf War, Update 2009

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Gulf War and Health

Volume 8: Update of Health Effects of Serving in the Gulf War

By: Institute of Medicine,Board on the Health of Select Populations,Committee on Gulf War and Health: Health Effects of Serving in the Gulf War, Update 2009

For the United States, the 1991 Persian Gulf War was a brief and successful military operation with few injuries and deaths. However, soon after returning from duty, a large number of veterans began reporting health problems they believed were associated with their service in the Gulf. At the request of Congress, the IOM is conducting an ongoing review of the evidence to determine veterans' long-term health problems and what might be causing those problems. The fourth volume in the series, released in 2006, summarizes the long-term health problems seen in Gulf War veterans. In 2008, the IOM began an update to look at existing health problems and identify possible new ones, considering evidence collected since the initial summary. In this report, the IOM determines that Gulf War service causes post-traumatic stress disorder (PTSD) and that service is associated with multisymptom illness; gastrointestinal disorders such as irritable bowel syndrome; alcohol and other substance abuse; and anxiety disorders and other psychiatric disorders. To ensure that our veterans receive the best possible care, now and in the future, the government should continue to monitor their health and conduct research to identify the best treatments to assist Gulf War veterans still suffering from persistent, unexplained illnesses.

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319

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National Academies Press

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ISBN 10

030915765X

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9780309157650

Gulf War and Health

Updated Literature Review of Sarin

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on Gulf War and Health: Updated Literature Review of Sarin

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Gulf War and Health

Updated Literature Review of Sarin

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on Gulf War and Health: Updated Literature Review of Sarin

The Gulf War in 1990-1991 was considered a brief and successful military operation, with few injuries or deaths of US troops. The war began in August 1990, and the last US ground troops returned home by June 1991. Although most Gulf War veterans resumed their normal activities, many soon began reporting a variety of nonexplained health problems that they attributed to their participation in the Gulf War, including chronic fatigue, muscle and joint pain, loss of concentration, forgetfulness, headache, and rash. Because of concerns about the veterans' health problems, the Department of Veterans Affairs (VA) requested that the Institute of Medicine (IOM) review the scientific and medical literature on the long-term adverse health effects of agents to which the Gulf War veterans may have been exposed. This report is a broad overview of the toxicology of sarin and cyclosarin. It assesses the biologic plausibility with respect to the compounds in question and health effects.

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132

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National Academies Press

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ISBN 10

0309165776

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9780309165778

Health Consequences of Service During the Persian Gulf War

Recommendations for Research and Information Systems

By: Institute of Medicine,Medical Follow-up Agency,Committee to Review the Health Consequences of Service During the Persian Gulf War

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Health Consequences of Service During the Persian Gulf War

Recommendations for Research and Information Systems

By: Institute of Medicine,Medical Follow-up Agency,Committee to Review the Health Consequences of Service During the Persian Gulf War

In January 1995 the Institute of Medicine released a preliminary report containing initial findings and recommendations on the federal government's response to reports by some veterans and their families that they were suffering from illnesses related to military service in the Persian Gulf War. The committee was asked to review the government's means of collecting and maintaining information for assessing the health consequences of military service and to recommend improvements and epidemiological studies if warranted. This new volume reflects an additional year of study by the committee and the full results of its three-year effort.

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212

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ISBN 10

0309055369

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9780309055369

Book's by Committee on the Development of a Consensus Case Definition for Chronic Multisymptom Illness in 1990-1991 Gulf War Veterans

Chronic Multisymptom Illness in Gulf War Veterans:

Chronic Multisymptom Illness in Gulf War Veterans:

Chronic Multisymptom Illness in Gulf War Veterans

Chronic Multisymptom Illness in Gulf War Veterans

Gulf War and Health

Gulf War and Health

The Air Force Health Study Assets Research Program

The Air Force Health Study Assets Research Program

Gulf War and Health

Gulf War and Health

Gulf War and Health

Gulf War and Health

Gulf War and Health

Gulf War and Health

Health Consequences of Service During the Persian Gulf War

Health Consequences of Service During the Persian Gulf War

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