Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam's Books

Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam

Interim Findings and Recommendations

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam

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Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam

Interim Findings and Recommendations

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam

From 1962 to 1971, US military forces sprayed more than 19 million gallons of herbicides over Vietnam to strip the thick jungle canopy that helped conceal opposition forces, to destroy crops that enemy forces might depend on, and to clear tall grass and bushes from around the perimeters of US base camps and outlying fire-support bases. Most large-scale spraying operations were conducted from airplanes and helicopters, but herbicides were also sprayed from boats and ground vehicles, and by soldiers wearing back-mounted equipment. After a scientific report concluded that a contaminant of one of the primary chemicals used in the herbicide called Agent Orange could cause birth defects in laboratory animals, US forces suspended use of the herbicide; they subsequently halted all herbicide spraying in Vietnam in 1971. At the request of the Veteran's Administration, the Institute of Medicine established a committee to oversee the development and evaluation of models of herbicide exposure for use in studies of Vietnam veterans. That committee would develop and disseminate a request for proposals (RFP) consistent with the recommendations; evaluate the proposals received in response to the RFP and select one or more academic or other nongovernmental research groups to develop the exposure reconstruction model; provide scientific and administrative oversight of the work of the researchers; and evaluate the models developed by the researchers in a report to VA, which would be published for a broader audience. Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam is the IOM's report that evaluates models of herbicide reconstruction to develop and test models of herbicide exposure for use in studies of Vietnam veterans.

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ISBN 10

0309089433

ISBN 13

9780309089432

Veterans and Agent Orange

Update 2014

By: National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on the Health of Select Populations,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Tenth Biennial Update)

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Veterans and Agent Orange

Update 2014

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ISBN 10

0309380693

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9780309380690

The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans

By: Institute of Medicine,Board on Military and Veterans Health,Committee on Making Best Use of the Agent Orange Exposure Reconstruction Model

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The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans

By: Institute of Medicine,Board on Military and Veterans Health,Committee on Making Best Use of the Agent Orange Exposure Reconstruction Model

A fundamental challenge in past studies evaluating whether health problems experienced by Vietnam veterans might be linked to wartime use of Agent Orange or other herbicides has been a lack of information about the veterans' level of exposure to these herbicides. To address that problem, researchers developed a model to assess the opportunity for herbicide exposure among these veterans. The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans presents the conclusions and recommendations of an Institute of Medicine committee (IOM) that was convened to provide guidance to the Department of Veterans Affairs (VA) about the best use of a model to characterize exposure to the troops based on their proximity to herbicide spraying in Vietnam. This book's assessment is guided by four primary considerations: to be clear about what the assessment model does and does not claim to do; to gain understanding of the strengths and limitations of data on herbicide spraying, troop locations, and health outcomes; to consider whether the model locates spraying and troops accurately to consider the potential contributions and pitfalls of using it in epidemiologic studies. Of particular interest in these deliberations were the degree to which exposure classification might be improved if the model were to be used, and the appropriate interpretation of the results of any such studies. In light of the questions that remain concerning herbicide exposure and health among Vietnam veterans and the array of evidence that has thus far been brought to bear on that issue, The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans concludes that the application of this model offers a constructive approach to extending knowledge about the effects of herbicides on the health of these veterans and merits the initial steps recommended in our report.

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160

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ISBN 10

030917810X

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9780309178105

Veterans and Agent Orange

Update 2008

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Seventh Biennial Update)

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Veterans and Agent Orange

Update 2008

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Seventh Biennial Update)

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707

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ISBN 10

0309147921

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9780309147927

Impact of Revised Airborne Exposure Limits on Non-Stockpile Chemical Materiel Program Activities

By: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Review and Assessment of the Army Non-Stockpile Chemical Materiel Demilitarization Program: Workplace Monitoring

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Impact of Revised Airborne Exposure Limits on Non-Stockpile Chemical Materiel Program Activities

The U.S. Army's Non-Stockpile Chemical Materiel program is responsible for dismantling former chemical agent production facilities and destroying recovered chemical materiel. In response to congressional requirements, the Center for Disease Control (CDC), in 2003, recommended new airborne exposure limits (AELs) to protect workforce and public health during operations to destroy this materiel. To assist in meeting these recommended limits, the U.S. Army asked the NRC for a review of its implementation plans for destruction of production facilities at the Newport Chemical Depot and the operation of two types of mobile destruction systems. This report presents the results of that review. It provides recommendations on analytical methods, on airborne containment monitoring, on operational procedures, on the applicability of the Resource Conservation and Recovery Act, and on involvement of workers and the public in implementation of the new AELs.

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108

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ISBN 10

0309181577

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9780309181570

Assessing the Human Health Risks of Trichloroethylene

Key Scientific Issues

By: National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Health Risks of Trichloroethylene

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Assessing the Human Health Risks of Trichloroethylene

Key Scientific Issues

By: National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Health Risks of Trichloroethylene

Trichloroethylene is a chlorinated solvent widely used as a degreasing agent in industrial and manufacturing settings. It is also used as a chemical intermediate in making other chemicals and is a component of products such as typewriter correction fluid, paint removers, adhesives, and spot removers. In 2001, EPA issued a draft health risk assessment and proposed exposure standards for trichloroethylene. PA's Scientific Advisory Board (SAB) reviewed the draft and it was issued for public comment. A number of scientific issues were raised during the course of these reviews. Assessing the Human Health Risks of Trichloroethylene identifies and assesses the key scientific issues relevant to analyzing the human health risks of trichloroethylene, considering pertinent toxicologic, epidemiologic, population susceptibility, and other available information, including relevant published scientific literature, EPA's 2001 draft health risk assessment of trichloroethylene, scientific and technical comments received by EPA from public and private sources, and additional relevant information to be provided by the sponsoring agencies. This report highlights issues critical to the development of an objective, realistic, and scientifically balanced trichloroethylene health risk assessment. Guidance for hazard characterization of trichloroethylene is presented in Chapters 2 through 10. Chapter 2 provides guidance for evaluating large sets of epidemiologic data. In Chapter 3, the committee applies this guidance as an example in its evaluation of the epidemiologic data on trichloroethylene and kidney cancer, and this example should help guide evaluations of other cancer risks. Chapter 3 also assesses new information on the kidney toxicity of trichloroethylene and its metabolites and potential modes of action. Chapters 4, 5, 6, 7, and 8 evaluate the key issues regarding liver toxicity and cancer, reproductive and developmental toxicity, neurotoxicity, respiratory tract toxicity and cancer, and immunotoxicity, respectively. However, the committee's review focused on mode-of-action information to understand how trichloroethylene might affect certain processes differently in different species. Chapter 9 discusses susceptibility to trichloroethylene and its metabolites, and Chapter 10 describes important factors in considering trichloroethylene in mixtures. Physiologically based pharmacokinetic models are evaluated in Chapter 11, and guidance is provided on future directions for model development. Finally, Chapter 12 considers issues related to dose-response assessment and quantitative assessment of risk.

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449

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ISBN 10

0309102839

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9780309102834

Escherichia coli O157:H7 in Ground Beef

Review of a Draft Risk Assessment

By: Institute of Medicine,Food and Nutrition Board,Board on Health Promotion and Disease Prevention,Committee on the Review of the USDA E. coli O157:H7 Farm-to-Table Process Risk Assessment

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Escherichia coli O157:H7 in Ground Beef

Review of a Draft Risk Assessment

By: Institute of Medicine,Food and Nutrition Board,Board on Health Promotion and Disease Prevention,Committee on the Review of the USDA E. coli O157:H7 Farm-to-Table Process Risk Assessment

USDA's Food Safety and Inspection Service (FSIS) is formulating risk assessments to identify important foodborne hazards; evaluate potential strategies to prevent, reduce, or eliminate those hazards; assess the effects of different mitigation strategies; and identify research needs. These risk assessments, in brief, empirically characterize the determinants of the presence or level of microbial contamination in vulnerable foodstuffs at various points leading up to consumption. One of the initial efforts in the undertaking is a risk assessment of the public health impact of E. coli O157:H7 in ground beef. In addition to soliciting public input, FSIS asked the Institute of Medicine (IOM) to convene a committee of experts to review the draft and offer recommendations and suggestions for consideration as the agency finalizes the document. This report presents the results of that review.

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172

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National Academies Press

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ISBN 10

0309086272

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9780309086271

Disposition of the Air Force Health Study

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Disposition of the Air Force Health Study

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Disposition of the Air Force Health Study

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Disposition of the Air Force Health Study

The Vietnam War was fought in a jungle environment that provided cover to the enemy and made battlefield observations difficult, so military strategists used herbicides to remove foliage along key roads and waterways, defoliate areas surrounding enemy bases and supply and communications routes, and improve visibility in heavily canopied forests. The last three decades have seen an ongoing debate about the effects of this military use of herbicides and the potential adverse long-term health effects on those who may have been exposed to these herbicides. In response to these concerns, the Air Force Health Study (AFHS) was created to investigate the potential relationship between the herbicides used and the health problems of those exposed. Disposition of the Air Force Health Study assesses the scientific merit of the AFHS operations and procedures, and makes recommendations for improvement.

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277

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0309100992

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9780309100991

The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans

By: Institute of Medicine,Board on Military and Veterans Health,Committee on Making Best Use of the Agent Orange Exposure Reconstruction Model

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The Utility of Proximity-Based Herbicide Exposure Assessment in Epidemiologic Studies of Vietnam Veterans

By: Institute of Medicine,Board on Military and Veterans Health,Committee on Making Best Use of the Agent Orange Exposure Reconstruction Model

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160

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030917810X

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9780309178105

Disposal of Activated Carbon from Chemical Agent Disposal Facilities

By: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee to Examine the Disposal of Activated Carbon from the Heating, Ventilation, and Air Conditioning Systems at Chemical Agent Disposal Facilities

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Disposal of Activated Carbon from Chemical Agent Disposal Facilities

For the last two decades, the United States has been destroying its entire stockpile of chemical agents. At the facilities where these agents are being destroyed, effluent gas streams pass through large activated carbon filters before venting to ensure that any residual trace vapors of chemical agents and other pollutants do not escape into the atmosphere in exceedance of regulatory limits. All the carbon will have to be disposed of for final closure of these facilities to take place. In March 2008, the Chemical Materials Agency asked the National Research Council to study, evaluate, and recommend the best methods for proper and safe disposal of the used carbon from the operational disposal facilities. This volume examines various approaches to handling carbon waste streams from the four operating chemical agent disposal facilities. The approaches that will be used at each facility will ultimately be chosen bearing in mind local regulatory practices, facility design and operations, and the characteristics of agent inventories, along with other factors such as public involvement regarding facility operations.

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0309138183

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9780309138185

Review of Chemical Agent Secondary Waste Disposal and Regulatory Requirements

By: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Review of Chemical Agent Secondary Waste Disposal and Regulatory Requirements

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Review of Chemical Agent Secondary Waste Disposal and Regulatory Requirements

Under the direction of the U.S. Army's Chemical Materials Agency (CMA) and mandated by Congress, the nation is destroying its chemical weapons stockpile. Large quantities of secondary waste are being generated in the process, and managing these wastes safely and effectively is a critical part of CMA's weapons disposal program. To assist, the CMA asked the NRC to examine the environmental and regulatory requirements that secondary waste treatment is subject to, and to assess best practices by industry in meeting such requirements for similar facilities. This book presents an overview of secondary wastes from chemical agent disposal facilities (CDF), a comparison of CDF and industry experience, site-specific analysis of major secondary waste issues, an examination of closure wastes, and findings and recommendations.

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0309106109

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9780309106108

Veterans and Agent Orange

Update 1998

By: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Second Biennial Update),Institute of Medicine

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Veterans and Agent Orange

Update 1998

By: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Second Biennial Update),Institute of Medicine

Third in a series of six congressionally mandated studies occurring biennially, this book is an updated review and evaluation of the available scientific evidence regarding the statistical association between exposure to herbicides used in Vietnam and various adverse health outcomes suspected to be linked with such exposures. As part of the review, the committee convened a workshop at which issues surrounding the reanalysis and the combination of existing data on the health effects of herbicide and dioxin exposure were addressed. This book builds upon the information developed by the IOM committees responsible for the 1994 original report, Veterans and Agent Orange, and Veterans and Agent Orange: Update 1996, but will focus on scientific studies and other information developed since the release of these reports. The two previous volumes have noted that sufficient evidence exists to link soft tissue sarcoma, non-Hodgkin's lymphoma, Hodgkin's disease, and chloracne with exposure. The books also noted that there is "limited or suggestive" evidence to show an association with exposure and a neurological disorder in veterans and with the congenital birth defect spina bifida in veterans' children. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

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625

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0309524687

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9780309524681

Veterans and Agent Orange

Health Effects of Herbicides Used in Vietnam

By: Institute of Medicine,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

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Veterans and Agent Orange

Health Effects of Herbicides Used in Vietnam

By: Institute of Medicine,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents: What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

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833

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0309048877

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9780309048873

Veterans and Agent Orange

Update 11 (2018)

By: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Eleventh Biennial Update)

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Veterans and Agent Orange

Update 11 (2018)

From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.

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739

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ISBN 10

0309477166

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9780309477161

Veterans and Agent Orange

Herbicide/Dioxin Exposure and Type 2 Diabetes

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Review the Evidence Regarding the Link Between Exposure to Agent Orange and Diabetes

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Veterans and Agent Orange

Herbicide/Dioxin Exposure and Type 2 Diabetes

By: Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee to Review the Evidence Regarding the Link Between Exposure to Agent Orange and Diabetes

In response to the concerns voiced by Vietnam veterans and their families, Congress called upon the National Academy of Sciences (NAS) to review the scientific evidence on the possible health effects of exposure to Agent Orange and other herbicides. This call resulted in the creation of the first NAS Institute of Medicine Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides in 1992. The committee published its initial findings in the 1994 report Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam. This report is the result of a 1999 request from the Department of Veterans Affairs (DVA) under the aegis of the Veterans and Agent Orange research program. Specifically, DVA asked the committee to examine evidence regarding the association, if any, between Type 2 diabetes and exposure to dioxin and other chemical compounds in herbicides used in Vietnam. Veterans and Agent Orange: Herbicide/Dioxin Exposure and Type 2 Diabetes reviews the scientific evidence regarding the association, if any, between Type 2 diabetes1 and exposure to dioxin2 and other chemical compounds in herbicides used in Vietnam. This report examines, to the extent that available data permitted meaningful determinations, (1) whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiologic methods used to detect the association; (2) the increased risk of the disease among those exposed to herbicides during Vietnam service; and (3) whether there is a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease.

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ISBN 10

0309171490

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9780309171496

Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft

By: Institute of Medicine,Board on the Health of Select Populations,Committee to Evaluate the Potential Exposure to Agent Orange/TCDD Residue and Level of Risk of Adverse Health Effects for Aircrew of Post-Vietnam C-123 Aircraft

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Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft

From 1972 to 1982, approximately 1,500-2,100 US Air Force Reserve personnel trained and worked on C-123 aircraft that had formerly been used to spray herbicides in Vietnam as part of Operation Ranch Hand. After becoming aware that some of the aircraft on which they had worked had previously served this purpose, some of these AF Reservists applied to the US Department of Veterans Affairs (VA) for compensatory coverage under the Agent Orange Act of 1991. The Act provides health care and disability coverage for health conditions that have been deemed presumptively service-related for herbicide exposure during the Vietnam War. The VA denied the applications on the basis that these veterans were ineligible because as non-Vietnam-era veterans or as Vietnam-era veterans without "boots on the ground" service in Vietnam, they were not covered. However, with the knowledge that some air and wipe samples taken between 1979 and 2009 from some of the C-123s used in Operation Ranch Hand showed the presence of agent orange residues, representatives of the C-123 Veterans Association began a concerted effort to reverse VA's position and obtain coverage. At the request of the VA, Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft evaluates whether or not service in these C-123s could have plausibly resulted in exposures detrimental to the health of these Air Force Reservists. The Institute of Medicine assembled an expert committee to address this question qualitatively, but in a scientific and evidence-based fashion. This report evaluates the reliability of the available information for establishing exposure and addresses and places in context whether any documented residues represent potentially harmful exposure by characterizing the amounts available and the degree to which absorption might be expected. Post-Vietnam Dioxin Exposure rejects the idea that the dioxin residues detected on interior surfaces of the C-123s were immobile and effectively inaccessible to the Reservists as a source of exposure. Accordingly, this report states with confidence that the Air Force Reservists were exposed when working in the Operation Ranch Hand C-123s and so experienced some increase in their risk of a variety of adverse responses.

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110

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0309308933

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9780309308939

Veterans and Agent Orange

Update 2002

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update)

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Veterans and Agent Orange

Update 2002

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update)

This book updates and evaluates the available scientific evidence regarding statistical associations between diseases and exposure to dioxin and other chemical compounds in herbicides used in Vietnam, focusing on new scientific studies and literature.

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638

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ISBN 10

0309168562

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9780309168564

Veterans and Agent Orange

Update 2002

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update)

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Veterans and Agent Orange

Update 2002

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update)

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639

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ISBN 10

0309086167

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9780309086165

Blue Water Navy Vietnam Veterans and Agent Orange Exposure

By: Institute of Medicine,Board on the Health of Select Populations,Committee on Blue Water Navy Vietnam Veterans and Agent Orange Exposure

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Blue Water Navy Vietnam Veterans and Agent Orange Exposure

By: Institute of Medicine,Board on the Health of Select Populations,Committee on Blue Water Navy Vietnam Veterans and Agent Orange Exposure

Over 3 million U.S. military personnel were sent to Southeast Asia to fight in the Vietnam War. Since the end of the Vietnam War, veterans have reported numerous health effects. Herbicides used in Vietnam, in particular Agent Orange have been associated with a variety of cancers and other long term health problems from Parkinson's disease and type 2 diabetes to heart disease. Prior to 1997 laws safeguarded all service men and women deployed to Vietnam including members of the Blue Navy. Since then, the Department of Veteran Affairs (VA) has established that Vietnam veterans are automatically eligible for disability benefits should they develop any disease associated with Agent Orange exposure, however, veterans who served on deep sea vessels in Vietnam are not included. These "Blue Water Navy" veterans must prove they were exposed to Agent Orange before they can claim benefits. At the request of the VA, the Institute of Medicine (IOM) examined whether Blue Water Navy veterans had similar exposures to Agent Orange as other Vietnam veterans. Blue Water Navy Vietnam Veterans and Agent Orange Exposure comprehensively examines whether Vietnam veterans in the Blue Water Navy experienced exposures to herbicides and their contaminants by reviewing historical reports, relevant legislation, key personnel insights, and chemical analysis to resolve current debate on this issue.

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158

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0309216214

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9780309216210

Veterans and Agent Orange

Update 1998

By: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Second Biennial Update),Institute of Medicine

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Veterans and Agent Orange

Update 1998

By: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Second Biennial Update),Institute of Medicine

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625

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ISBN 10

0309524687

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9780309524681

Veterans and Agent Orange

Update 2014

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Veterans and Agent Orange

Update 2014

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1115

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ISBN 10

0309380693

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9780309380690

Veterans and Agent Orange

Length of Presumptive Period for Association Between Exposure and Respiratory Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

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Veterans and Agent Orange

Length of Presumptive Period for Association Between Exposure and Respiratory Cancer

By: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

From 1962 to 1971, US military forces sprayed herbicides over Vietnam to strip the thick jungle canopy that helped conceal opposition forces, to destroy crops that enemy forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the majority of the herbicides sprayed. Agent Orange was a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, one form of dioxin) was an unintended contaminant from the production of 2,4,5-T and was present in Agent Orange and some other formulations sprayed in Vietnam. In 1991, because of continuing uncertainty about the long-term health effects on Vietnam veterans of the herbicides sprayed, Congress passed Public Law 102-4, the Agent Orange Act of 1991. In response to the request from the VA, IOM extended the service of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides that was responsible for Update 2002 to address the question of presumptive period and respiratory cancer. The charge to the committee was to undertake a review and evaluation of the evidence regarding the period between cessation of exposure to herbicides used in Vietnam and their contaminants (2,4-D, 2,4,5-T and its contaminant TCDD, cacodylic acid, and picloram) and the occurrence of respiratory cancer.

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ISBN 10

0309091888

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9780309091886

Veterans and Agent Orange

Update 2006

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Sixth Biennial Update)

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Veterans and Agent Orange

Update 2006

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Sixth Biennial Update)

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Page Count

895

Publisher

National Academies Press

Published Date

ISBN 10

030914552X

ISBN 13

9780309145527

Veterans and Agent Orange

Update 2008

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Seventh Biennial Update)

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Veterans and Agent Orange

Update 2008

By: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Seventh Biennial Update)

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Page Count

707

Publisher

National Academies Press

Published Date

ISBN 10

0309147921

ISBN 13

9780309147927

Veterans and Agent Orange

Update 2012

By: Institute of Medicine,Board on the Health of Select Populations,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update)

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Veterans and Agent Orange

Update 2012

By: Institute of Medicine,Board on the Health of Select Populations,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update)

From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010-September 2012 and integrates this information with the previously established evidence database. This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease.

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Page Count

802

Publisher

National Academies Press

Published Date

ISBN 10

0309288894

ISBN 13

9780309288897

Book's by Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam

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