Committee on Laboratory Security and Personnel Reliability Assurance Systems for Laboratories Conducting Research on Biological Select Agents and Toxins's Books

Responsible Research with Biological Select Agents and Toxins

By: National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Laboratory Security and Personnel Reliability Assurance Systems for Laboratories Conducting Research on Biological Select Agents and Toxins

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Responsible Research with Biological Select Agents and Toxins

The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

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188

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National Academies Press

Published Date

ISBN 10

030914535X

ISBN 13

9780309145350

Responsible Research with Biological Select Agents and Toxins

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Responsible Research with Biological Select Agents and Toxins

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188

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National Academies Press

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ISBN 10

030914535X

ISBN 13

9780309145350

Promoting Chemical Laboratory Safety and Security in Developing Countries

By: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Promoting Safe and Secure Chemical Management in Developing Countries

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Promoting Chemical Laboratory Safety and Security in Developing Countries

By: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Promoting Safe and Secure Chemical Management in Developing Countries

There is growing concern about the possible use of toxic industrial chemicals or other hazardous chemicals by those seeking to perpetrate acts of terrorism. The U.S. Chemical Security Engagement Program (CSP), funded by the U.S. Department of State and run by Sandia National Laboratories, seeks to develop and facilitate cooperative international activities that promote best practices in chemical security and safe management of toxic chemicals, including: Partnering with host governments, chemical professionals, and industry to assess and fill gaps in chemical security abroad. Providing technical expertise and training to improve best practices in security and safety among chemical professionals and industry. Increasing transparency and accountability for dangerous chemical materials, expertise, and technologies. Providing opportunities for collaboration with the international professional chemical community. The Department of State called on the National Academies to assist in the CSP's efforts to promote chemical safety and security in developing countries.

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137

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National Academies Press

Published Date

ISBN 10

0309161355

ISBN 13

9780309161350

Safe Science

Promoting a Culture of Safety in Academic Chemical Research

By: National Research Council,Division of Behavioral and Social Sciences and Education,Board on Human-Systems Integration,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Establishing and Promoting a Culture of Safety in Academic Laboratory Research

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Safe Science

Promoting a Culture of Safety in Academic Chemical Research

Recent serious and sometimes fatal accidents in chemical research laboratories at United States universities have driven government agencies, professional societies, industries, and universities themselves to examine the culture of safety in research laboratories. These incidents have triggered a broader discussion of how serious incidents can be prevented in the future and how best to train researchers and emergency personnel to respond appropriately when incidents do occur. As the priority placed on safety increases, many institutions have expressed a desire to go beyond simple compliance with regulations to work toward fostering a strong, positive safety culture: affirming a constant commitment to safety throughout their institutions, while integrating safety as an essential element in the daily work of laboratory researchers. Safe Science takes on this challenge. This report examines the culture of safety in research institutions and makes recommendations for university leadership, laboratory researchers, and environmental health and safety professionals to support safety as a core value of their institutions. The report discusses ways to fulfill that commitment through prioritizing funding for safety equipment and training, as well as making safety an ongoing operational priority. A strong, positive safety culture arises not because of a set of rules but because of a constant commitment to safety throughout an organization. Such a culture supports the free exchange of safety information, emphasizes learning and improvement, and assigns greater importance to solving problems than to placing blame. High importance is assigned to safety at all times, not just when it is convenient or does not threaten personal or institutional productivity goals. Safe Science will be a guide to make the changes needed at all levels to protect students, researchers, and staff.

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162

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National Academies Press

Published Date

ISBN 10

0309300940

ISBN 13

9780309300940

Chemical Laboratory Safety and Security

A Guide to Developing Standard Operating Procedures

By: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Chemical Management Toolkit Expansion: Standard Operating Procedures

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Chemical Laboratory Safety and Security

A Guide to Developing Standard Operating Procedures

The U.S. Department of State charged the Academies with the task of producing a protocol for development of standard operating procedures (SOPs) that would serve as a complement to the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and be included with the other materials in the 2010 toolkit. To accomplish this task, a committee with experience and knowledge in good chemical safety and security practices in academic and industrial laboratories with awareness of international standards and regulations was formed. The hope is that this toolkit expansion product will enhance the use of the previous reference book and the accompanying toolkit, especially in developing countries where safety resources are scarce and experience of operators and end-users may be limited.

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117

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National Academies Press

Published Date

ISBN 10

0309392233

ISBN 13

9780309392235

Prudent Practices in the Laboratory

Handling and Management of Chemical Hazards, Updated Version

By: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Prudent Practices in the Laboratory: An Update

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Prudent Practices in the Laboratory

Handling and Management of Chemical Hazards, Updated Version

By: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Prudent Practices in the Laboratory: An Update

Prudent Practices in the Laboratory-the book that has served for decades as the standard for chemical laboratory safety practice-now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students.

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360

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National Academies Press

Published Date

ISBN 10

0309138647

ISBN 13

9780309138642

Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

By: National Research Council,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Board on Life Sciences,Committee on the Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

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Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

Safeguarding U.S. agriculture from foreign animal diseases and protecting our food system require cutting-edge research and diagnostic capabilities. The Department of Homeland Security (DHS) and the U.S. Department of Agriculture (USDA) have embarked on an important mission to replace the aging Plum Island Animal Disease Center (PIADC) with a new facility, the National Bio- and Agro-Defense Facility (NBAF). When operational, this new facility would be the world's fourth biosafety level-4 laboratory capable of large animal research. It would serve as a critical world reference laboratory for identifying emerging and unknown disease threats, and would thus be a critical asset in securing the future health, wealth, and security of the nation. DHS selected Manhattan, Kansas, as the site for the new NBAF after an extensive site-selection process that involved an environmental impact statement. The Government Accountability Office (GAO) raised concerns about DHS's analysis of the potential spread of foot-and-mouth disease virus (FMDv), one of the most serious foreign animal disease threats. Congress directed DHS to conduct a site-specific risk assessment (SSRA) for the NBAF, instructed the National Research Council (NRC) to independently evaluate the SSRA, and prohibited obligation of NBAF construction funds until the NRC review was complete. Congress mandated that DHS revise its SSRA to address shortcomings of the 2010 SSRA, directed the NRC to evaluate the updated SSRA (uSSRA), and again prohibited obligation of construction funds until the completion of the second review. The scope for both of these SSRA reports addressed accidental release of pathogens from the NBAF in Manhattan, Kansas and excluded terrorist acts and malicious threats from its risk assessments. Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas is the evaluation of the final uSSRA.

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Page Count

132

Publisher

National Academies Press

Published Date

ISBN 10

0309257859

ISBN 13

9780309257855

Book's by Committee on Laboratory Security and Personnel Reliability Assurance Systems for Laboratories Conducting Research on Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins

Promoting Chemical Laboratory Safety and Security in Developing Countries

Promoting Chemical Laboratory Safety and Security in Developing Countries

Safe Science

Safe Science

Chemical Laboratory Safety and Security

Chemical Laboratory Safety and Security

Prudent Practices in the Laboratory

Prudent Practices in the Laboratory

Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

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