Committee on Immunologically Compromised Rodents's Books

Immunodeficient Rodents

A Guide to Their Immunobiology, Husbandry, and Use

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Immunologically Compromised Rodents

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Immunodeficient Rodents

A Guide to Their Immunobiology, Husbandry, and Use

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Immunologically Compromised Rodents

This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.

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Page Count

257

Publisher

National Academies Press

Published Date

ISBN 10

0309092876

ISBN 13

9780309092876

Rodents

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Rodents

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Rodents

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Rodents

In the 15 years since the last Institute of Laboratory Animal Resources report on the general management of rodents was published, important advances in biomedical research and increased public awareness have created a new environment for animal research. Modern technology-such as insertion of functional genes from other species into mice or rats, elimination of a single selected gene or function in mice, and the re-creation of elements of the human immune system in mice-has greatly expanded the usefulness of rodents in drug development and as models of human diseases. The technologic requirements of such advanced systems have led to improved understanding and implementation of environmental requirements for the care and use of rodents in research. The intent of this report is to provide current information to laboratory animal scientists (including both animal-care technicians and veterinarians), investigators, research technicians, and administrators on general elements of rodent care and use that should be considered both for optimal design and conduct of research and to meet current standards of care and use.

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Page Count

180

Publisher

National Academies Press

Published Date

ISBN 10

0309049369

ISBN 13

9780309049368

Rodents

By: Committee on Rodents,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

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Rodents

By: Committee on Rodents,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council

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180

Publisher

National Academies Press

Published Date

ISBN 10

0309585775

ISBN 13

9780309585774

Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

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Infectious Diseases of Mice and Rats

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats

This new editionâ€"a must for all researchers who use these lab animalsâ€"provides practical suggestions for breeding, keeping, and identifying pathogen-free laboratory rodents. It contains three informative sections. The first, Principles of Rodent Disease Prevention, summarizes methods for eliminating infectious agents. It offers information on pathogen terminology; pathogen status of rodents; and breeding, transporting, isolating, testing, and diagnosing rodents. The second section, Individual Disease Agents and Their Effects on Research, describes the diagnosis and control of each infectious agent, and the last section, Diagnostic Indexes: Clinical Signs, Pathology, and Research Complications, contains informative tables covering all the diseases listed in the volume, arranged to help in the diagnosis of infected animals.

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Page Count

410

Publisher

National Academies Press

Published Date

ISBN 10

0309063329

ISBN 13

9780309063326

Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

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Guide for the Care and Use of Laboratory Animals

Eighth Edition

By: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

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Page Count

246

Publisher

National Academies Press

Published Date

ISBN 10

0309154006

ISBN 13

9780309154000

Laboratory Animal Management

Dogs

By: National Research Council,Institute of Laboratory Animal Resources,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Dogs

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Laboratory Animal Management

Dogs

By: National Research Council,Institute of Laboratory Animal Resources,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on Dogs

This newly revised edition incorporates the regulatory requirements and improved practices for laboratory animal care that have developed over the past two decades. The volume covers: Selection of dogs as research models. Design, construction, and maintenance of facilities. Temperature, humidity, food, water, bedding, sanitation, animal identification, record keeping, and transportation. General veterinary care, as well as special care of breeding animals and random-source animals. Laboratory Animal Management: Dogs examines controversies over proper cage sizes and interpretation of federal requirements for exercise and offers recommendations for researchers. Guidelines are provided on how to recognize and alleviate pain and distress in research dogs and on the sensitive topic of euthanasia. Laboratory Animal Management: Dogs discusses how to assemble a proper research protocol and how to handle conflicts. Outlined are procedures for institutional animal care and use and committee review. The volume also presents guidelines for handling aging dogs, use of radiation in experiments, and a wide range of other special circumstances. Thoroughly referenced, this guide will be indispensable to researchers, research administrators, review committees, and others concerned about laboratory dogs.

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Page Count

156

Publisher

National Academies Press

Published Date

ISBN 10

0309047447

ISBN 13

9780309047449

Immunodeficient Rodents

A Guide to Their Immunobiology, Husbandry, and Use

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Immunologically Compromised Rodents

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Immunodeficient Rodents

A Guide to Their Immunobiology, Husbandry, and Use

By: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Immunologically Compromised Rodents

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Page Count

257

Publisher

National Academies Press

Published Date

ISBN 10

0309037964

ISBN 13

9780309037969

Effects of Ionizing Radiation

UNSCEAR 2006 Report to the General Assembly, with Scientific Annexes

By: United Nations. Scientific Committee on the Effects of Atomic Radiation

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Effects of Ionizing Radiation

UNSCEAR 2006 Report to the General Assembly, with Scientific Annexes

By: United Nations. Scientific Committee on the Effects of Atomic Radiation

The purpose of this annex is to summarize the literature on non-targeted effects associated with exposure to ionizing radiation and, where possible, to evaluate how such effects may affect risks associated with radiation exposure, the understanding of radiation-induced carcinogenesis, and the mechanistic basis for interpreting epidemiological data on radiation effects.

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Page Count

344

Publisher

United Nations Publications

Published Date

ISBN 10

9211422701

ISBN 13

9789211422702

Book's by Committee on Immunologically Compromised Rodents

Immunodeficient Rodents

Immunodeficient Rodents

Rodents

Rodents

Rodents

Rodents

Infectious Diseases of Mice and Rats

Infectious Diseases of Mice and Rats

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Laboratory Animal Management

Laboratory Animal Management

Immunodeficient Rodents

Immunodeficient Rodents

Effects of Ionizing Radiation

Effects of Ionizing Radiation

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