Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research's Books

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Workshop Report

By: National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Write a review Read reviews Take a Quiz Solve Book Puzzle

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Workshop Report

It is widely understood that stem cell treatments have the potential to revolutionize medicine. Because of this potential, in 2004 California voters approved Proposition 71 to set up a 10-year, $3 billion program to fund research on stem cells. Under the direction of the California Institute for Regenerative Medicine, this program will pay to build facilities for stem cell research and will fund doctors and scientists to carry out research with the ultimate goal of helping to develop therapies based on stem cells. For this research to move forward, however, will require a steady supply of stem cells, particularly human embryonic stem cells. Those stem cells are collected from developing human embryos created from eggs-or oocytes-harvested from the ovaries of female donors. Thus much of the promise of stem cells depends on women choosing to donate oocytes to the research effort. The oocyte donation process is not without risk, however. Donors are given doses of hormones to trigger the production of more eggs than would normally be produced, and this hormone treatment can have various side effects. Once the eggs have matured in the ovary, they must be retrieved via a surgical procedure that is typically performed under anesthesia, and both the surgery and the anesthesia carry their own risks. Furthermore, given the very personal nature of egg donation, the experience may carry psychological risks for some women as well. With this in mind, in 2006 the California Institute for Regenerative Medicine contracted with the National Academies to organize a workshop that would bring together experts from various areas to speak about the potential risks of oocyte donation and to summarize what is known and what needs to be known about this topic. The Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research was formed to plan the workshop, which was held in San Francisco on September 28, 2006. This report is a summary and synthesis of that workshop.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

112

Publisher

National Academies Press

Published Date

ISBN 10

030910355X

ISBN 13

9780309103558

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

By: National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology

Write a review Read reviews Take a Quiz Solve Book Puzzle

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

300

Publisher

National Academies Press

Published Date

ISBN 10

0309178894

ISBN 13

9780309178891

Veterans and Agent Orange

Update 2010

By: Institute of Medicine,Board on the Health of Select Populations,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Eighth Biennial Update)

Write a review Read reviews Take a Quiz Solve Book Puzzle

Veterans and Agent Orange

Update 2010

By: Institute of Medicine,Board on the Health of Select Populations,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Eighth Biennial Update)

Because of continuing uncertainty about the long-term health effects of the sprayed herbicides on Vietnam veterans, Congress passed the Agent Orange Act of 1991. The legislation directed the Secretary of Veterans Affairs (VA) to request the Institite of Medicine to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange and other herbicides used in Vietnam to be followed by biennial updates. The 2010 update recommends further research of links between Vietnam service and specific health outcomes, most importantly COPD, tonsil cancer, melanoma, brain cancer, Alzheimer's disease, and paternally transmitted effects to offspring.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

836

Publisher

National Academies Press

Published Date

ISBN 10

0309214475

ISBN 13

9780309214476

The California Institute for Regenerative Medicine

Science, Governance, and the Pursuit of Cures

By: Institute of Medicine,Board on Health Sciences Policy,Committee on a Review of the California Institute for Regenerative Medicine

Write a review Read reviews Take a Quiz Solve Book Puzzle

The California Institute for Regenerative Medicine

Science, Governance, and the Pursuit of Cures

By: Institute of Medicine,Board on Health Sciences Policy,Committee on a Review of the California Institute for Regenerative Medicine

The California Institute for Regenerative Medicine (CIRM) was created in 2005 by The California Stem Cell Research and Cures Act (Proposition 71) to distribute $3 billion in state funds for stem cell research. The passage of Proposition 71 by the voters of California occurred at a time when federal funding for research involving human embryonic stem cells was uncertain, given the ethical questions raised by such research. During its initial period of operations, CIRM has successfully and thoughtfully provided more than $1.3 billion in awards to 59 California institutions, consistent with its stated mission. As it transitions to a broadened portfolio of grants to stimulate progress toward its translational goals, the Institute should obtain cohesive, longitudinal, and integrated advice; restructure its grant application review process; and enhance industry epresentation in aspects of its operations. CIRM's unique governance structure, while seful in its initial stages, might diminish its effectiveness moving forward. The California Institute for Regenerative Medicine: Science, Governance, and the Pursuit of Cures recommends specific steps to enhance CIRM's organization and management, as well as its scientific policies and processes, as it transitions to the critical next stages of its research and development program.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

177

Publisher

National Academies Press

Published Date

ISBN 10

0309265908

ISBN 13

9780309265904

Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

Write a review Read reviews Take a Quiz Solve Book Puzzle

Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

In 2005, the National Academies released the book, Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national standards for research. In order to keep the Guidelines up to date, given the rapid pace of scientific and policy developments in the field of stem cell research, the Human Embryonic Stem Cell Research Advisory Committee was established in 2006 with support from The Ellison Medical Foundation, The Greenwall Foundation, and the Howard Hughes Medical Institute. As it did in 2007 and 2008, the Committee identified issues that warranted revision, and this book addresses those issues in a third and final set of amendments. Specifically, this book sets out an updated version of the National Academies' Guidelines, one that takes into account the new, expanded role of the NIH in overseeing hES cell research. It also identifies those avenues of continuing National Academies' involvement deemed most valuable by the research community and other significant stakeholders.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

Publisher

National Academies Press

Published Date

ISBN 10

0309156009

ISBN 13

9780309156004

Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research

Write a review Read reviews Take a Quiz Solve Book Puzzle

Guidelines for Human Embryonic Stem Cell Research

Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

224

Publisher

National Academies Press

Published Date

ISBN 10

0309096537

ISBN 13

9780309096539

2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

Write a review Read reviews Take a Quiz Solve Book Puzzle

2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

In 2005, the National Academies released the report Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national standards for research. In order to keep the Guidelines up to date, given the rapid pace of scientific developments in the field of stem cell research, the Human Embryonic Stem Cell Research Advisory Committee was established in 2006 with support from The Ellison Medical Foundation, The Greenwall Foundation, and the Howard Hughes Medical Institute. As it did in 2007, the Committee identified issues that warranted revision, and this book addresses those issues in a second set of amendments. Most importantly, this book addresses new scientific developments in reprogramming of somatic cells to pluripotency by adding a new section and revising other relevant sections of the Guidelines.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

Publisher

National Academies Press

Published Date

ISBN 10

0309122201

ISBN 13

9780309122207

2007 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

Write a review Read reviews Take a Quiz Solve Book Puzzle

2007 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

By: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Human Embryonic Stem Cell Research Advisory Committee

In 2005, the National Academies released the report Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national standards for research. In order to keep the Guidelines up to date, given the rapid pace of scientific developments in the field of stem cell research, the Human Embryonic Stem Cell Research Advisory Committee was established in 2006 with support from The Ellison Medical Foundation, The Greenwall Foundation, and the Howard Hughes Medical Institute. This letter report is the committee's first set of amendments to the Guidelines and clarifies earlier recommendations and conclusions, including the criteria for determining which stem cell lines it is acceptable to use. Future deliberations of the committee will address items for which additional information gathering and more extensive debate and discussion will be necessary.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

Publisher

National Academies Press

Published Date

ISBN 10

0309105595

ISBN 13

9780309105590

Book's by Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Veterans and Agent Orange

Veterans and Agent Orange

The California Institute for Regenerative Medicine

The California Institute for Regenerative Medicine

Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

Guidelines for Human Embryonic Stem Cell Research

Guidelines for Human Embryonic Stem Cell Research

2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

2007 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

2007 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

Username

Password

Username

Password

Password again

Birthday

Email