The rapid progress in genomics and related technologies has increased interest in genetically modified organisms (GMOs). This book equips you with information about what genes are, how they work, and how they can be modified and used in biotechnology. On environmental genetics, it also considers the risks of releasing agricultural GM plants.
The first five chapters of this book form an introductory course in piece wise-linear topology in which no assumptions are made other than basic topological notions. This course would be suitable as a second course in topology with a geometric flavour, to follow a first course in point-set topology, andi)erhaps to be given as a final year undergraduate course. The whole book gives an account of handle theory in a piecewise linear setting and could be the basis of a first year postgraduate lecture or reading course. Some results from algebraic topology are needed for handle theory and these are collected in an appendix. In a second appen dix are listed the properties of Whitehead torsion which are used in the s-cobordism theorem. These appendices should enable a reader with only basic knowledge to complete the book. The book is also intended to form an introduction to modern geo metric topology as a research subject, a bibliography of research papers being included. We have omitted acknowledgements and references from the main text and have collected these in a set of "historical notes" to be found after the appendices.
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