I was asked to introduce this volume by examining "why a knowledge of ecosys tem functioning can contribute to understanding species activities, dynamics, and assemblages." I have found it surprisingly difficult to address this topic. On the one hand, the answer is very simple and general: because all species live in ecosystems, they are part of and dependent on ecosystem processes. It is impossible to understand the abundance and distribution of populations and the species diversity and composition of communities without a knowledge of their abiotic and biotic environments and of the fluxes of energy and mat ter through the ecosystems of which they are a part. But everyone knows this. It is what ecology is all about (e.g., Likens, 1992). It is why the discipline has retained its integrity and thrived, despite a sometimes distressing degree of bickering and chauvinism among its various subdisciplines: physiological, be havioral, population, community, and ecosystem ecology.
Ecology is an historical science in which theories can be as difficult to test as they are to devise. This volume, intended for ecologists and evolutionary biologists, reviews ecological theories, and how they are generated, evaluated, and categorized. Synthesizing a vast and sometimes labyrinthine literature, this book is a useful entry into the scientific philosophy of ecology and natural history. The need for integration of the contributions to theory made by different disciplines is a central theme of this book. The authors demonstrate that only through such integration will advances in ecological theory be possible. Ecologists, evolutionary biologists, and other serious students of natural history will want this book.
People with personality disorder who offend tend to be neglected by health services in most countries. In the UK, there has been renewed interest in the field since government initiatives in the end of the 1990s. Government proposals themselves are controversial, but there is growing recognition that it is unsafe, both for the general public and fo
Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been developed by select centers of excellence in industry and academia, and are continually being fine tuned in the race to identify the best antibody-based drug candidates and accelerate their paths to patients. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field and to offer specialized perspectives to established researchers. The chapters set into context the significance of key developments and important considerations for selecting different approaches, such as antibody humanization, isotype selection, lead candidate selection criteria and protein production. All contributors to this work are experts in their fields, and many have played pivotal roles in the creation of these technologies.
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